Spermidine, a polyamine widely distributed in living organisms, has attracted widespread attention in the field of scientific research in recent years. Scientists have found that spermidine plays an important role in promoting longevity, providing new ideas for healthy longevity by regulating cellular autophagy, inhibiting oxidative stress and other mechanisms.
First, spermidine can promote cellular autophagy. Autophagy is an important mechanism by which cells renew and repair themselves by breaking down their damaged or excess organelles and proteins in response to stress or aging. Spermine can induce the transcription of autophagy-related genes, thus enhancing cellular autophagy. This action not only helps to remove toxins and harmful substances accumulated in cells, but also maintains the normal function of cells and slows down the process of cellular aging.
Secondly, Spermidine can inhibit oxidative stress. Oxidative stress refers to the imbalance of redox reactions in cells, leading to excessive accumulation of reactive oxygen radicals (ROS) and other oxidative substances, which in turn cause damage to cells. Spermidine has an antioxidant effect, which can scavenge intracellular ROS and reduce the damage to cells caused by oxidative stress. At the same time, spermidine can also improve the antioxidant capacity of cells and enhance the resistance of cells to oxidative stress, thereby protecting cells from damage.
In addition, spermidine has anti-cancer effects. Several studies have shown that supplementation with spermidine can reduce the risk of tumour development and slow down the growth of tumours. Spermidine can inhibit the proliferation and invasion of tumour cells and induce apoptosis, thus exerting anti-cancer effects. At the same time, spermidine can also enhance anti-tumour immune response and improve the body’s resistance to tumours.
In addition to the above effects, spermidine can also maintain gene stability. Genetic stability is the basis for normal cell function, and spermidine can bind and precipitate DNA, preventing DNA damage and mutation. This action helps maintain the genetic stability of cells and reduces the occurrence of genetic mutations and diseases.
So how can you increase the level of spermidine in your body? One way is to increase your intake of foods rich in spermidine. Foods such as wheat and whole grains, broccoli and cauliflower, mushrooms, peas, mangoes, soya beans and soya products are good sources of spermidine. By combining these foods wisely, we can provide our body with enough spermidine to fulfil its role in promoting longevity.
In addition, spermidine supplements are also a way to increase the level of spermidine in the body. However, it should be noted that further research and validation on the safety and effectiveness of spermidine supplements is needed. Therefore, before using spermidine supplements, it is recommended to consult a professional doctor or dietitian to ensure its safety and reasonableness.
In conclusion, as an important bioactive substance, spermidine plays an important role in promoting longevity. By promoting cellular autophagy, inhibiting oxidative stress, anti-cancer and other mechanisms, spermidine helps to maintain normal cellular function and slow down the process of cellular aging. By increasing the intake of foods rich in Spermidine or using spermidine supplements, we can increase the level of spermidine in our body and thus enjoy the health benefits it brings. However, when using spermidine supplements, we also need to be careful to ensure their safety and reasonableness.
