Black Seed Extract
Thymoquinone
Thymoquinone (TQ) is the core bioactive compound extracted from Nigella Sativa (Black Cumin Seed). As a professional herbal extract manufacturer Focusherb, we supply standardized thymoquinone powder (5%,10%,20%) and high purity 98% thymoquinone crystal monomer, tested by GC-FID method for stable potency.
We support bulk wholesale, private label OEM, customized purity compound formula and full third-party GC lab testing. Our TQ raw materials are widely supplied to global dietary supplement factories, cosmetic brands, pet nutrition manufacturers and functional food producers. Please contact us for get thymoquinone cost per kg for tiered wholesale price reference.
Halal Kosher
USDA Organic Seed Source
Full Batch GC COA
Heavy Metal Free
PRODUCT INTRODUCTION
| Product Name | Thymoquinone / Nigella Sativa Extract |
| CAS Number | 490-91-5 L |
| Part Used | Seed of devil-in-the-bush |
| Raw Material | Dried Nigella Sativa Black Cumin Seed |
| Appearance | Orange fine powder (5%/10%/20%); Orange crystalline solid (98%) |
| Standard Purity Options | 5%, 10%, 20% Thymoquinone Powder; 98% High Purity Monomer |
| Bulk Packing | 1kg aluminum foil bag, 25kg food grade fiber drum; neutral export packaging available |
| Certifications | ISO22000, GMP, USDA Organic Seed Source, Halal, Kosher, Third-party GC COA |
| MOQ | 1kg bulk powder / 100g high purity crystal sample |
| Shelf Life | 24 months sealed cool dark storage, avoid light & oxidation |
Low-Temp Cold Extraction & Molecular Purification Process
We adopt full low-temperature closed extraction line to prevent thymoquinone oxidation and activity loss, strictly GMP clean workshop production, multi-stage purification remove free fatty acid and plant impurities to guarantee stable TQ content.
- Organic black cumin seed screening & impurity removal
Low-temperature cold oil extraction to lock natural thymoquinone - Vacuum negative pressure distillation concentration
- Molecular distillation separate TQ from oil impurities
- Low temp recrystallization for 98% high purity crystal
- Aseptic drying, sifting & light-proof sealed bulk packaging
Our low-temp purification technology keeps stable anti-inflammatory & antioxidant activity.

Factory Qualification, Annual Output & Stable Ready Stock
Our herbal extract production plant passes ISO22000 & GMP global food safety audit, self-owned organic Nigella Sativa planting base to guarantee stable raw material supply, every batch complete GC detection for thymoquinone content, heavy metal and microbial limit test.
Stable Production Capacity & Warehouse Ready Stock
- Total annual output: 80 tons standardized thymoquinone extract powder, 5 tons 98% high purity crystal monomer
- Permanent warehouse ready stock: 6–12 tons mixed purity powder, fast shipment within 3–7 working days
- Independent light-proof cold storage warehouse to avoid TQ oxidation discoloration
- Dual parallel extraction & purification lines, support seasonal large bulk rush order
- ISO22000 Global Food Safety Management System
- GMP Standard Clean Herbal Extract Workshop
- USDA Organic Nigella Sativa Planting Certificate
- Halal & Kosher Global Export Religious Certification
- Independent third-party GC lab full batch testing system
Every shipment attaches official batch COA, GC chromatogram test data, heavy metal report and SDS safety specification sheet.



GC Test Batch COA Report
Core Biological Functions & Active Benefits
Powerful Anti-Inflammatory Activity
Inhibit COX & LOX inflammatory pathways, relieve joint, respiratory and skin inflammatory reactions, widely used in joint health supplements.
Strong Natural Antioxidant
Neutralize body free radicals, reduce oxidative stress, delay cell aging, core raw material for anti-aging skincare & wellness blends.
Liver & Cardiovascular Protection
Protect liver cells from oxidative damage, assist lipid regulation, support heart & liver health oral capsule formulas.
Immune Modulation Support
Regulate immune cell activity, enhance body self-defense, ideal ingredient for daily immune support supplements.
Broad-Spectrum Antibacterial & Antifungal
Inhibit staphylococcus aureus and skin fungi, added in acne, scalp care & anti-dandruff cosmetic formulas.
Pet Functional Nutrition Additive
Relieve pet skin inflammation, improve coat condition, boost pet immunity for dog & cat supplement oil/powder.
Have any questions?Let’s get in touch!
Contact us if your are thinking of purchasing highquality ingredients, develop new products, or justsolving a manufacturing challenge in your rawmaterials.
Main Application Fields
Human Dietary Supplement Capsule
Joint health, liver care, immune support softgel & tablet OEM raw material
Anti-Inflammatory Cosmetic Raw Material
Acne serum, anti-dandruff shampoo, sensitive skin repair cream additive
Pet Functional Nutrition Raw Material
Pet skin care powder, immunity boost supplementary oil additive
Functional Food & Meal Blend Powder
Anti-oxidant compound meal powder, functional solid drink raw material
Strict Quality Inspection & Batch COA Document
Each batch thymoquinone completes comprehensive lab detection: GC-FID thymoquinone content assay, moisture, loss on drying, heavy metal (Pb, As, Hg, Cd), residual solvent, total aerobic bacteria, yeast & mold count.
We provide independent third-party GC COA, full chromatogram file, SDS safety data sheet and technical specification sheet upon customer request for customs clearance and brand registration.
Full Batch Traceable QC System
Every bulk order matches exclusive batch number & complete lab test record
OEM & Private Label Custom Service
Full Custom Support Range
- Purity customization: 5%/10%/20% standard powder, 98% high purity crystal monomer
- Compound blended formula: mix with black seed oil, vitamin, herbal extracts
- Finished capsule OEM: hard/soft capsule filled with thymoquinone powder
- Private label aluminum bag, fiber drum packaging label design & printing
- Neutral export bulk packing without Focusherb logo for global distributors
For customized bulk order cost budget, please contact us to get price reference.

Thymoquinone Function
-
Anti-cancer
Thymoquinone has been shown to affect many different signaling pathways in various types of cancer, including P53, P73, TWIST1, nf-κb, MAPK, PI3K/AKT, PTEN, STAT3, peroxisome proliferator-activated receptor gamma (ppar-γ ) and reactive oxygen species (Ros). This makes it a promising candidate for an anticancer small molecule.
Thymoquinone has been shown to induce apoptosis in cervical cancer (Siha and C33a), leukemia (HL60), human sarcoma(MG63 and MNNG/HOS), skin squamous cell carcinoma, and gastric cancer (HGC-27).
-
Antioxidation
Over one hundred diseases have been linked to an overabundance of free radicals, or the body’s inability to properly eliminate them. Free radicals freely travel through the body, attacking cells and causing damage to proteins, enzymes, DNA, and cell mutations. This can lead to degenerative diseases such as weakened blood vessels, aging brain cells, weakened immune systems, and osteoarthritis.
However, thymoquinone has been shown to delay the auto-oxidation process of oil, and its antioxidant effect increases with concentration. Therefore, thymoquinone has a significant antioxidant effect and the ability to eliminate free radicals.
-
Liver protection
Thymoquinone has a hepatoprotective effect by blocking caspase activation, MAPK signaling pathway, and activating AMPK signaling pathway. Thymoquinone inhibits alcoholic liver disease by activating AMPK and SIRT1 protein expression, thereby improving ethanol-induced triglyceride accumulation.
In conclusion, thymoquinone has a significant protective effect on acute liver injury and has potential pharmacological therapeutic value.
Why Choose FocusHerb Thymoquinone?
FocusHerb has been dedicated to the cultivation and research of devil’s tears for a number of years. We offer Fruits and Vegetable at a reasonable cost.
They go through an intense independent examination to make sure that they are safe for consumption globally.
How to buy Thymoquinone?
Just send an email to admin@xafhbio.com, or submit your needs at the bottom, we’re here for you!
Related Products
Have any questions?
Let's get in touch!
Contact us if your are thinking of purchasing highquality ingredients, develop new products, or justsolving a manufacturing challenge in your rawmaterials.



















