Sophora japonica Extract

Sophora japonica Extract


  • Specifications:30%~98%
  • Appearance:Yellow fine powder
  • Extraction Source:The fruit of Sophora japonicus
  • Test Method:HPLC
  • Extraction Solvent: Ethanol/Water
  • CAS Number:520-18-3


Kaempferol is an organic substance, belonging to the flavonoid class, which is extracted from the dried ripe fruit of Sophora flavescens. Kaempferol is slightly soluble in water, soluble in hot ethanol, ether and DMSO and other organic solvents.Mainly used for anti-cancer, anti-fertility, anti-epileptic, anti-inflammatory, anti-oxidant, antispasmodic, anti-ulcer, choleretic and diuretic, antitussive.

Product Name Kaempferol
Specifications 30%~98%
Appearance Yellow fine powder
Extraction Source The fruit of Sophora japonicus
Test Method HPLC
Product Alias Tetrahydroflavonoids, Kaempferol-3
Extraction Solvent  Ethanol/Water
CAS Number 520-18-3
Molecular Formula C15H10O6
Molecular Weight 286.23
Physical Properties Melting point 276℃-278℃. Kaempferol is slightly soluble in water, soluble in hot ethanol, ether and alkali.
Particle Size 100% over 80 mesh
Recommended Addition Amount The amount of propolis added is 0.12%-0.2%

Recommended dosage of health care products: 15mg

Kaempferol Benefits

  • Anti-cancer

Kaempferol mainly regulates the transcription of cyclooxygenase-2, inhibits the function and expression of P-glycoprotein, inhibits interleukin-4 against cell proliferation, induces apoptosis, interferes with cell signal transduction and enhances tumor suppressor genes It has anti-cancer effects in terms of activity and inhibition of oncogene expression. Among them, it inhibits tumor cell proliferation by inducing tumor cell apoptosis.

  • Antioxidant

Kaempferol has the function of inhibiting the formation of AGE (Advanced glycation endproducts) and eliminating free radicals. It also has a strong antioxidant effect in preventing intracellular lipids and DNA oxidative damage. It can also regulate the levels of NO and NOS, and protect endothelial cells from oxidative damage by inhibiting the degradation of NO.

 Anti-fertility, anti-osteoporosis

Kaempferol has obvious anti-fertility effects on animals and exhibits estrogen-like activity. Estrogen has a direct proliferation effect on osteoblasts, and it also has a significant promotion effect on the differentiation of osteoblasts after proliferation, so it is clinically used to prevent and treat osteoporosis.

  • Hypoglycemic effect

Kaempferol can improve diabetic endothelial dysfunction, improve the ability of microvascular lumen, effectively prevent type 2 diabetic cardiomyopathy and diabetic blood vessels, and is expected to become a new generation of insulin sensitizer.


It has inhibitory effect on Staphylococcus aureus, Pseudomonas aeruginosa, Typhoid bacillus and Shigella bacillus.

 Kaempferol Applications

  • food
  • functional food
  • health products
  • medicine
  • nutritional supplements

Kaempferol  Advantages

FocusHerb has focused on producing Sophora Japonica extract for more than ten years,We can control the quality and stability of raw materials from the source. From incoming raw materials to final products, we strictly follow GMP requirements to ensure the product quality of Kaempferol.

The company has advanced imported testing equipment to ensure traceability testing from raw materials to production.The professional technical team strictly controls the quality and quality.Low pesticide residues, low solvent residues and high purity are the basis of our products.

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