Diosgenin

Diosgenin is a plant steroid classified as a sapogenin. It is extracted from the roots of Dioscorea wild yam and is commonly used as a precursor in the formulation of synthetic steroid compounds such as progesterone and cortisone.

Studies have shown that diosgenin has antioxidant, anti-vascular calcification, anti-tumor, anti-inflammatory, anti-allergic, anti-viral and anti-shock effects.

Diosgenin Function

How does Diosgenin work?

As a steroidal compound, Diosgenin plays several active roles in the human body for improved wellness. Foremost, the compound is a phytoestrogen that is chemically converted into biologically identical progesterone as that of the naturally occurring form of the hormone. As such, Diosgenin is claimed to promote progesterone levels and help maintain its normal levels in the body.

According to studies, the compound effectively modulates multiple signaling events and patterns in cells involved in proliferation, differentiation, and apoptosis. This mechanism is essential in understanding claims that the compound may possess anti-proliferative and anti-cancer properties. Diosgenin also works as an antioxidant, thereby reducing oxidative stress and damage in healthy living cells.

The compound is also found to possess protective properties against metabolic conditions as it effectively helps prevent adipose tissue inflammation and promote adipocyte differentiation.

Health Benefits of Diosgenin

• It supports women’s health

Diosgenin helps prevent hormonal imbalances and prevent rapid distortion in estrogen and progesterone levels.

• It soothes occasional gastrointestinal discomfort

Diosgenin supplementation may provide gastroprotective benefits against gastric mucosal injury through the suppression of certain actions of some enzymes.

• It may help promote breast enlargement

It is claimed that the use of Diosgenin supplements may help promote breast enlargement as the compound effectively enhances hormonal levels.

Uses of diosgenin

Dioscorea saponin is a precursor for the synthesis of steroid hormone drugs, and is used to synthesize various steroid drugs such as hydrocortisone, prednisone, norethisterone, fucoidan, and dexamethasone.

Diosgenin dosage and bioavailability

The recommended dosage for Diosgenin supplementation depends on the individual user’s age, weight, and overall physical condition.

The bioavailability of the compound may be enhanced through the combination of β-Cyclodextin and liquid crystal Diosgenin.