{"id":2771,"date":"2025-10-11T05:59:50","date_gmt":"2025-10-11T05:59:50","guid":{"rendered":"https:\/\/www.focusherb.com\/kr\/?post_type=blog&p=2771"},"modified":"2025-10-11T06:02:18","modified_gmt":"2025-10-11T06:02:18","slug":"pqq-%ec%82%b6%ea%b3%bc-%ea%b1%b4%ea%b0%95%ec%9d%98-%ec%95%94%ed%98%b8%eb%a5%bc-%ed%92%80%ec%96%b4%ec%a3%bc%eb%8a%94-%eb%a7%88%eb%b2%95%ec%9d%98-%eb%ac%bc%ec%a7%88","status":"publish","type":"blog","link":"https:\/\/www.focusherb.com\/kr\/blog\/pqq-%ec%82%b6%ea%b3%bc-%ea%b1%b4%ea%b0%95%ec%9d%98-%ec%95%94%ed%98%b8%eb%a5%bc-%ed%92%80%ec%96%b4%ec%a3%bc%eb%8a%94-%eb%a7%88%eb%b2%95%ec%9d%98-%eb%ac%bc%ec%a7%88\/","title":{"rendered":"PQQ: \uc0b6\uacfc \uac74\uac15\uc758 \uc554\ud638\ub97c \ud480\uc5b4\uc8fc\ub294 \ub9c8\ubc95\uc758 \ubb3c\uc9c8"},"content":{"rendered":"

\ucd5c\uadfc \uba87 \ub144 \ub3d9\uc548 PQQ(\ud53c\ub864\ub85c\ud034\ub180\ub9b0\ud034\ub17c)\ub77c\ub294 \ubb3c\uc9c8\uc774 \uac74\uac15 \ubd84\uc57c\uc5d0\uc11c \ube60\ub974\uac8c \uc778\uae30\ub97c \uc5bb\uc73c\uba70 \uac74\uac15 \uc804\ubb38\uac00\uc640 \uc5f0\uad6c\uc790\ub4e4\uc758 \uc8fc\ubaa9\uc744 \ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ub9ce\uc740 \uc0ac\ub78c\ub4e4\uc774 PQQ\ub97c \uac74\uac15\uc758 \ube44\ubc00\uc744 \ubc1d\ud600\uc8fc\ub294 “\ub9c8\ubc95\uc758 \uc5f4\uc1e0”\ub85c \uc5ec\uae41\ub2c8\ub2e4. \ub2e4\ub978 \uc218\ub9ce\uc740 \uc601\uc591 \uc131\ubd84\ub4e4 \uc911\uc5d0\uc11c\ub3c4 PQQ\uac00 \ub3cb\ubcf4\uc774\ub294 \uc774\uc720\ub294 \ubb34\uc5c7\uc77c\uae4c\uc694? \ub2e8\uc21c\ud55c \uacfc\ub300\uad11\uace0\uc77c\uae4c\uc694, \uc544\ub2c8\uba74 \uc815\ub9d0 \uae30\uc801\uc801\uc778 \ud6a8\ub2a5\uc744 \uac00\uc9c4 \uac83\uc77c\uae4c\uc694? PQQ\uc758 \uc2e0\ube44\ub97c \ud480\uace0 \uadf8 \ub4a4\uc5d0 \uc228\uaca8\uc9c4 \uacfc\ud559\uc801 \ube44\ubc00\uc744 \uc0b4\ud3b4\ubcf4\uaca0\uc2b5\ub2c8\ub2e4.\"\"<\/p>\n

PQQ\ub780 \ubb34\uc5c7\uc77c\uae4c\uc694?<\/h2>\n

(I) \ub3c5\ud2b9\ud55c \ud654\ud559 \uad6c\uc870<\/h3>\n

PQQ\ub294 \ud53c\ub864\ub85c\ud034\ub180\ub9b0\ud034\ub17c\uc73c\ub85c\ub3c4 \uc54c\ub824\uc838 \uc788\uc73c\uba70, \uc77c\ubc18\uc801\uc73c\ub85c \ubd89\uc740\uc0c9 \uacb0\uc815\uc9c8 \ubd84\ub9d0 \ud615\ud0dc\ub85c \ub098\ud0c0\ub0a9\ub2c8\ub2e4. \uc774 \ub3c5\ud2b9\ud55c \ud654\ud559 \uad6c\uc870\ub294 PQQ<\/strong><\/a>\uc5d0 \ub180\ub77c\uc6b4 \uc0dd\ubb3c\ud559\uc801 \ud65c\uc131\uc744 \ubd80\uc5ec\ud558\uba70, \uc218\ub9ce\uc740 \uc0dd\ub9ac \uacfc\uc815\uc5d0\uc11c \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. PQQ \ubd84\uc790 \ub0b4\uc758 \ud53c\ub864 \uace0\ub9ac, \ud034\ub180\ub9b0 \uace0\ub9ac, \uadf8\ub9ac\uace0 \ud034\ub17c \uad6c\uc870\ub294 \ud568\uaed8 \uc548\uc815\uc801\uc774\uace0 \ub192\uc740 \ud65c\uc131\uc744 \uac00\uc9c4 \ud654\ud559 \uc2dc\uc2a4\ud15c\uc744 \ud615\uc131\ud569\ub2c8\ub2e4. \ud654\ud559 \ubc18\uc751\uc5d0\uc11c PQQ\uc758 \ud034\ub17c \uad6c\uc870\ub294 \uc804\uc790\ub97c \ubc1b\uc544\ub4e4\uc774\uace0 \ub0b4\uc8fc\uba70 \uc0b0\ud654\ud658\uc6d0 \ubc18\uc751\uc5d0 \ucc38\uc5ec\ud558\uc5ec \ud6a8\uc728\uc801\uc778 \uc804\uc790 \uc804\ub2ec “\uc804\ub2ec\uc18c” \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud2b9\uc131\uc73c\ub85c \uc778\ud574 PQQ\ub294 \uc138\ud3ec \uc5d0\ub108\uc9c0 \ub300\uc0ac\uc5d0 \ud544\uc218\uc801\uc778 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uc138\ud3ec \ud638\ud761 \uacfc\uc815\uc5d0\uc11c PQQ\ub294 \uc804\uc790 \uc804\ub2ec\uacc4\uc5d0 \ucc38\uc5ec\ud558\uc5ec \uc138\ud3ec\uac00 \uc601\uc591\uc18c\ub97c \uc5d0\ub108\uc9c0\ub85c \ub354 \ud6a8\uc728\uc801\uc73c\ub85c \uc804\ud658\ud558\ub3c4\ub85d \ub3d5\uace0, \ub2e4\uc591\ud55c \uc138\ud3ec \ud65c\ub3d9\uc5d0 \ucda9\ubd84\ud55c \uc5d0\ub108\uc9c0\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \ub610\ud55c, PQQ\uc758 \ub3c5\ud2b9\ud55c \ubd84\uc790 \uad6c\uc870\ub294 \ub2e8\ubc31\uc9c8\uc774\ub098 \ud6a8\uc18c\uc640 \uac19\uc740 \ud2b9\uc815 \uc0dd\uccb4 \uace0\ubd84\uc790\uc640 \uc0c1\ud638 \uc791\uc6a9\ud560 \uc218 \uc788\ub3c4\ub85d \ud569\ub2c8\ub2e4. \uc815\ud655\ud55c \ubd84\uc790 \uc778\uc2dd\uc744 \ud1b5\ud574 \uad00\ub828 \uc0dd\ubb3c\ud559\uc801 \uacfc\uc815\uc744 \ud65c\uc131\ud654\ud558\uac70\ub098 \uc870\uc808\ud558\uc5ec \uc138\ud3ec\uc758 \uc131\uc7a5, \ubc1c\ub2ec, \ubd84\ud654\uc5d0 \uc9c0\ub300\ud55c \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4.<\/p>\n

(II) \ucc9c\uc5f0\uc758 \ubcf4\uace0<\/h3>\n

PQQ\ub294 \uc790\uc5f0\uacc4\uc758 \ub2e4\uc591\ud55c \uc2dd\ud488\uc5d0\uc11c \ub110\ub9ac \ubc1c\uacac\ub429\ub2c8\ub2e4. \ub18d\ub3c4\ub294 \ub2e4\uc591\ud558\uc9c0\ub9cc \ubd84\ud3ec \ubc94\uc704\ub294 \uad11\ubc94\uc704\ud569\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc778 \uc2dd\ud488 \uc911 \uc2dc\uae08\uce58\uc640 \ube0c\ub85c\ucf5c\ub9ac\uc640 \uac19\uc740 \ub179\uc0c9 \ucc44\uc18c\ub294 PQQ\uc758 “\ucc9c\uc5f0 \uc800\uc7a5\uc18c”\uc785\ub2c8\ub2e4. \uc2dc\uae08\uce58\uc5d0\ub294 100g\ub2f9 \uc57d 23.7\u03bcg\uc758 PQQ\uac00 \ud568\uc720\ub418\uc5b4 \uc788\uc73c\uba70, \ube0c\ub85c\ucf5c\ub9ac\uc5d0\ub3c4 100g\ub2f9 \uc57d 18.9\u03bcg\uc758 \uc0c1\ub2f9\ud55c \uc591\uc774 \ud568\uc720\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4. \uacfc\uc77c \uc911 \ud0a4\uc704\ub294 PQQ\uc758 \ubcf4\uace0\ub85c, \uacfc\uc721 100g\ub2f9 \uc57d 11.3\u03bcg\uc758 PQQ\ub97c \ud568\uc720\ud558\uace0 \uc788\uc5b4 \uacfc\uc77c \uc560\ud638\uac00\ub4e4\uc5d0\uac8c \ucc9c\uc5f0 PQQ \uacf5\uae09\uc6d0\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc721\ub958 \ubc0f \uc720\uc81c\ud488\uacfc \uac19\uc740 \ub3d9\ubb3c\uc131 \uc2dd\ud488\uc5d0\ub3c4 \uc77c\uc815\ub7c9\uc758 PQQ\uac00 \ud568\uc720\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4. \uc18c\uace0\uae30\uc5d0\ub294 100g\ub2f9 \uc57d 10.8\u03bcg\uc758 PQQ\uac00 \ud568\uc720\ub418\uc5b4 \uc788\uc73c\uba70, \uc6b0\uc720\ub294 \ube44\uad50\uc801 \uc801\uc740 \uc591\uc774\uc9c0\ub9cc \uc0c1\ub2f9\ud55c \uc591\uc758 PQQ\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \ub0ab\ud1a0\uc640 \uac19\uc740 \ubc1c\ud6a8 \uc2dd\ud488\uc740 PQQ\uc758 \ud6cc\ub96d\ud55c \uacf5\uae09\uc6d0\uc774\uba70, 100g\ub2f9 \ucd5c\ub300 61.0\u03bcg\uc758 PQQ \ud568\ub7c9\uc744 \uc790\ub791\ud558\uc5ec \uc77c\ubc18 \uc2dd\ud488 \uc911\uc5d0\uc11c\ub3c4 \uc911\uc694\ud55c \uacf5\uae09\uc6d0\uc785\ub2c8\ub2e4.<\/p>\n

\uc548\ud0c0\uae5d\uac8c\ub3c4 \uc778\uccb4\ub294 PQQ\ub97c \uc2a4\uc2a4\ub85c \ud569\uc131\ud560 \uc218 \uc5c6\uae30 \ub54c\ubb38\uc5d0 \uc774 \ud544\uc218 \ubb3c\uc9c8\uc744 \uc678\ubd80\uc5d0\uc11c \uacf5\uae09\ubc1b\uc544\uc57c \ud569\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc2dd\ud488 \ub0b4 PQQ \ud568\ub7c9\uc774 \uc77c\ubc18\uc801\uc73c\ub85c \ub0ae\uae30 \ub54c\ubb38\uc5d0 \uc2dd\ub2e8\ub9cc\uc73c\ub85c\ub294 \uc2e0\uccb4\uac00 \ud544\uc694\ub85c \ud558\ub294 PQQ\ub97c \ucda9\ubd84\ud788 \ucda9\uc871\ud558\uae30 \uc5b4\ub835\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uc5f0\uad6c\uc5d0\uc11c \uc77c\ubc18\uc801\uc73c\ub85c \uc0ac\uc6a9\ub418\ub294 10~20mg\uc758 PQQ \ubcf4\ucda9\uc81c \ubcf5\uc6a9\ub7c9\uc744 \uae30\uc900\uc73c\ub85c, \uc2dc\uae08\uce58\ub9cc\uc73c\ub85c \uc774 \uc815\ub3c4\uc758 PQQ\ub97c \uc5bb\uc73c\ub824\uba74 \ud558\ub8e8\uc5d0 \uc57d 422~844kg\uc758 \uc2dc\uae08\uce58\ub97c \uc12d\ucde8\ud574\uc57c \ud558\ub294\ub370, \uc774\ub294 \ubd84\uba85\ud788 \ube44\ud604\uc2e4\uc801\uc785\ub2c8\ub2e4. \ub530\ub77c\uc11c PQQ\uc758 \uac74\uac15\uc0c1\uc758 \uc774\uc810\uc744 \ucd5c\ub300\ud55c \ud65c\uc6a9\ud558\uace0\uc790 \ud558\ub294 \uc0ac\ub78c\ub4e4\uc5d0\uac8c\ub294 \uc801\uc808\ud55c \uc601\uc591 \ubcf4\ucda9\uc81c \uc12d\ucde8\uac00 \ud569\ub9ac\uc801\uc774\uace0 \ud6a8\uacfc\uc801\uc778 \uc120\ud0dd\uc785\ub2c8\ub2e4.<\/p>\n

PQQ\uc758 \ud0c1\uc6d4\ud55c \ud6a8\ub2a5<\/h2>\n

\"\"<\/p>\n

(I) \ud56d\uc0b0\ud654 \uae30\ub2a5\uc758 \uc120\uad6c\uc790<\/h3>\n

\uc778\uccb4\uc758 \ub300\uc0ac \uacfc\uc815\uc5d0\uc11c \ud65c\uc131\uc0b0\uc18c\ub294 \ub04a\uc784\uc5c6\uc774 \uc0dd\uc131\ub429\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud65c\uc131\uc0b0\uc18c\ub294 \ub9c8\uce58 \ub04a\uc784\uc5c6\uc774 \ubb38\uc81c\ub97c \uc77c\uc73c\ud0a4\ub294 “\ubb38\uc81c \uc720\ubc1c \ubb3c\uc9c8”\ucc98\ub7fc \ubc18\uc751\uc131\uc774 \ub9e4\uc6b0 \ub192\uc544 \uc138\ud3ec \uac74\uac15\uc744 \ub04a\uc784\uc5c6\uc774 \uc704\ud611\ud569\ub2c8\ub2e4. \ud65c\uc131\uc0b0\uc18c \uc0dd\uc131\ub7c9\uc774 \uc2e0\uccb4\uc758 \uc81c\uac70 \ub2a5\ub825\uc744 \ucd08\uacfc\ud558\uba74 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uac00 \ubc1c\uc0dd\ud558\ub294\ub370, \uc774\ub294 DNA, \ub2e8\ubc31\uc9c8, \uc9c0\uc9c8\uacfc \uac19\uc740 \uc138\ud3ec \ub0b4 \ub2e4\uc591\ud55c \u200b\u200b\uc0dd\uccb4 \ubd84\uc790\ub97c \uacf5\uaca9\ud558\ub294 “\uc0b0\ud654 \ud3ed\ud48d”\uacfc \uac19\uc740 \ud604\uc0c1\uc73c\ub85c, \uc138\ud3ec \uad6c\uc870\uc640 \uae30\ub2a5\uc744 \uc190\uc0c1\uc2dc\ud0a4\uace0 \ub178\ud654, \uc2ec\ud608\uad00 \uc9c8\ud658, \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658\uc744 \ud3ec\ud568\ud55c \ub2e4\uc591\ud55c \uac74\uac15 \ubb38\uc81c\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4.<\/p>\n

PQQ\ub294 \ud65c\uc131\uc0b0\uc18c\uc640 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc5d0 \ub9de\uc11c \uc2f8\uc6b0\ub294 “\uc288\ud37c\ud788\uc5b4\ub85c”\uc785\ub2c8\ub2e4. PQQ\uc758 \ubd84\uc790 \uad6c\uc870\ub294 \uac15\ub825\ud55c \ud56d\uc0b0\ud654 \ud2b9\uc131\uc744 \ubd80\uc5ec\ud558\uc5ec “\uc804\uc790 \uc2a4\ud380\uc9c0”\ucc98\ub7fc \ud65c\uc131\uc0b0\uc18c\ub97c \uc9c1\uc811 \ud3ec\ud68d\ud558\uace0 \uc911\ud654\uc2dc\ucf1c \uc774\ub7ec\ud55c \uc704\ud5d8\ud55c “\ubb38\uc81c \uc720\ubc1c \ubb3c\uc9c8”\uc744 \uc548\uc815\ub41c \ubb3c\uc9c8\ub85c \uc804\ud658\uc2dc\ucf1c \uc138\ud3ec\uc5d0 \ub300\ud55c \uacf5\uaca9\uacfc \uc190\uc0c1\uc744 \uc904\uc785\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 PQQ\ub294 \ud65c\uc131\uc0b0\uc18c \uc81c\uac70\uc5d0 \ub9e4\uc6b0 \ud6a8\uacfc\uc801\uc785\ub2c8\ub2e4. \ud2b9\uc815 \uc2e4\ud5d8 \uc870\uac74\uc5d0\uc11c, PQQ\ub294 \uc288\ud37c\uc625\uc0ac\uc774\ub4dc \uc74c\uc774\uc628 \ub77c\ub514\uce7c\uacfc \ud558\uc774\ub4dc\ub85d\uc2e4 \ub77c\ub514\uce7c\uacfc \uac19\uc740 \uc77c\ubc18\uc801\uc778 \uc790\uc720 \ub77c\ub514\uce7c\uc744 \uc81c\uac70\ud558\ub294 \ub2a5\ub825\uc774 \ube44\ud0c0\ubbfc C\uc640 \ube44\ud0c0\ubbfc E\uc640 \uac19\uc740 \uae30\uc874 \ud56d\uc0b0\ud654\uc81c\ubcf4\ub2e4 \ub6f0\uc5b4\ub0a9\ub2c8\ub2e4. PQQ\ub294 \uc790\uc720 \ub77c\ub514\uce7c\uc744 \uc9c1\uc811 \uc81c\uac70\ud558\ub294 \uac83 \uc678\uc5d0\ub3c4 \uc138\ud3ec \ub0b4 \ud56d\uc0b0\ud654 \ubc29\uc5b4 \uc2dc\uc2a4\ud15c\uc744 \ud65c\uc131\ud654\ud558\uc5ec \uc138\ud3ec\uc758 \ud56d\uc0b0\ud654 \ub2a5\ub825\uc744 \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. “\uc9c0\ud718\uad00”\ucc98\ub7fc \uc791\uc6a9\ud558\uc5ec Nrf2\/ARE \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \ud65c\uc131\ud654\ud558\uace0 \uc288\ud37c\uc625\uc0ac\uc774\ub4dc \ub514\uc2a4\ubba4\ud0c0\uc544\uc81c(SOD)\uc640 \uae00\ub8e8\ud0c0\ud2f0\uc628 \ud37c\uc625\uc2dc\ub2e4\uc544\uc81c(GPx)\uc640 \uac19\uc740 \ud56d\uc0b0\ud654 \ud6a8\uc18c\uc758 \ud65c\uc131\uc744 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud56d\uc0b0\ud654 \ud6a8\uc18c\ub294 \uc138\ud3ec\uc758 “\ubc29\uc5b4\ub9c9” \uc5ed\ud560\uc744 \ud558\uba70, \uc790\uc720 \ub77c\ub514\uce7c \uc190\uc0c1\uc744 \ub9c9\uae30 \uc704\ud574 \uc2dc\ub108\uc9c0 \ud6a8\uacfc\ub97c \ubc1c\ud718\ud569\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, SOD\ub294 \uc288\ud37c\uc625\uc0ac\uc774\ub4dc \uc74c\uc774\uc628 \ub77c\ub514\uce7c\uc744 \uacfc\uc0b0\ud654\uc218\uc18c\ub85c \uc804\ud658\ud558\uace0, GPx\ub294 \uacfc\uc0b0\ud654\uc218\uc18c\ub97c \ubb3c\ub85c \ud658\uc6d0\uc2dc\ucf1c \uc790\uc720 \ub77c\ub514\uce7c\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uc81c\uac70\ud558\uace0 \uc138\ud3ec \ub0b4 \uc0b0\ud654\ud658\uc6d0 \uade0\ud615\uc744 \uc720\uc9c0\ud569\ub2c8\ub2e4. \uc0dd\uc950\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \uc5f0\uad6c\uc5d0\uc11c PQQ \ubcf4\ucda9\uc740 SOD\uc640 GPx \ud65c\uc131\uc744 \uc720\uc758\ubbf8\ud558\uac8c \uc99d\uac00\uc2dc\ud0a4\uace0 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \uc9c0\ud45c\uc778 \ub9d0\ub860\ub514\uc54c\ub370\ud788\ub4dc(MDA) \uc218\uce58\ub97c \uc720\uc758\ubbf8\ud558\uac8c \uac10\uc18c\uc2dc\ucf1c PQQ\uac00 \ud56d\uc0b0\ud654 \ubc29\uc5b4 \uccb4\uacc4\ub97c \uac15\ud654\ud558\ub294 \ub370 \ud0c1\uc6d4\ud55c \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0c4\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

(II) \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc758 \uc218\ud638\uc790<\/h3>\n

\uc138\ud3ec\uc758 “\uc5d0\ub108\uc9c0 \uacf5\uc7a5”\uc73c\ub85c \uc54c\ub824\uc9c4 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 \uc138\ud3ec \uc0dd\ud65c\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 \uc77c\ub828\uc758 \ubcf5\uc7a1\ud55c \uc0dd\ud654\ud559 \ubc18\uc751\uc744 \ud1b5\ud574 \uc74c\uc2dd\uc758 \ud654\ud559 \uc5d0\ub108\uc9c0\ub97c \uc138\ud3ec\uac00 \uc9c1\uc811 \ud65c\uc6a9\ud560 \uc218 \uc788\ub294 \uc5d0\ub108\uc9c0 \ud615\ud0dc\uc778 \uc544\ub370\ub178\uc2e0 \uc0bc\uc778\uc0b0(ATP)\uc73c\ub85c \uc804\ud658\ud569\ub2c8\ub2e4. \uc774\ub294 \uc138\ud3ec \uc131\uc7a5, \ubd84\uc5f4, \uc6b4\ub3d9\uc744 \ud3ec\ud568\ud55c \ub2e4\uc591\ud55c \uc0dd\ub9ac \ud65c\ub3d9\uc5d0 \uc9c0\uc18d\uc801\uc778 \uc5d0\ub108\uc9c0\uc6d0\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \ub610\ud55c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 \uc138\ud3ec\uc790\uba78\uc0ac \ubc0f \ub300\uc0ac \uc870\uc808\uacfc \uac19\uc740 \uc911\uc694\ud55c \uacfc\uc815\uc5d0 \ucc38\uc5ec\ud558\uc5ec \uc815\uc0c1\uc801\uc778 \uc138\ud3ec \uae30\ub2a5\uacfc \ub0b4\ubd80 \ud658\uacbd \uc548\uc815\uc131\uc744 \uc720\uc9c0\ud558\ub294 \ub370 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4.
\nPQQ\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc758 \uc131\uc7a5 \ubc0f \ubc1c\ub2ec\uc744 \ucd09\uc9c4\ud558\uace0 \uc5d0\ub108\uc9c0 \ub300\uc0ac\ub97c \ud5a5\uc0c1\uc2dc\ud0a4\ub294 \ub370 \uc788\uc5b4 \ub300\uccb4 \ubd88\uac00\ub2a5\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. PGC-1\u03b1(peroxisome proliferator-activated receptor \u03b3 coactivator 1\u03b1)\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc0dd\ud569\uc131\uc758 “\ub9c8\uc2a4\ud130 \uc2a4\uc704\uce58”\ub85c \uc54c\ub824\uc9c4 \ud575\uc2ec \ub2e8\ubc31\uc9c8\uc785\ub2c8\ub2e4. PGC-1\u03b1\uac00 \ud65c\uc131\ud654\ub418\uba74 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc0dd\ud569\uc131\uc744 \ucd09\uc9c4\ud558\ub294 \uc77c\ub828\uc758 \uc720\uc804\uc790\ub97c \ud65c\uc131\ud654\uc2dc\ucf1c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 “\uc0dd\uc0b0 \uacf5\uc7a5”\uc744 \uac00\ub3d9\ud569\ub2c8\ub2e4. \uc774\ub294 \uc138\ud3ec \ub0b4 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc758 \uc218\uc640 \uc9c8\uc744 \uc99d\uac00\uc2dc\ucf1c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 PQQ\ub97c \ubcf4\ucda9\ud558\uba74 \uc138\ud3ec \ub0b4 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ubc00\ub3c4\uc640 ATP \uc0dd\uc131\uc774 \ud06c\uac8c \uc99d\uac00\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uac04\uc138\ud3ec \uc2e4\ud5d8\uc5d0\uc11c PQQ\ub97c \ud22c\uc5ec\ud558\uba74 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc218\uac00 \uc57d 30% \uc99d\uac00\ud558\uace0 ATP \uc0dd\uc131\uc774 1.5\ubc30 \uc99d\uac00\ud558\uc5ec \uc138\ud3ec \uc5d0\ub108\uc9c0 \ub300\uc0ac \ud6a8\uc728\uc774 \ud06c\uac8c \ud5a5\uc0c1\ub418\uc5c8\uc74c\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4. PQQ\ub294 \ub610\ud55c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc804\uc790 \uc804\ub2ec\uacc4\uc758 \uae30\ub2a5\uc744 \ucd5c\uc801\ud654\ud569\ub2c8\ub2e4. \uc804\uc790 \uc804\ub2ec\uacc4\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 ATP \uc0dd\uc131\uc758 \ud575\uc2ec \ub2e8\uacc4\uc774\uba70, \ud6a8\uc728\uc801\uc778 “\uc5d0\ub108\uc9c0 \uc0dd\uc0b0 \ub77c\uc778” \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc816\uc0b0 \ud0c8\uc218\uc18c\ud6a8\uc18c(LDH)\uc640 \uac19\uc740 \ud6a8\uc18c\uc758 \ubcf4\uc870 \ud6a8\uc18c\uc778 PQQ\ub294 \uc804\uc790 \uc804\ub2ec \uacfc\uc815\uc5d0 \ucc38\uc5ec\ud558\uc5ec NADH(\ud658\uc6d0\ub41c \ubcf4\uc870 \ud6a8\uc18c I)\uc758 NAD\u207a(\uc0b0\ud654\ub41c \ubcf4\uc870 \ud6a8\uc18c I)\ub85c\uc758 \uc804\ud658\uc744 \ucd09\uc9c4\ud558\uace0, \ud53c\ub8e8\ube0c\uc0b0 \uc0dd\uc131\uc744 \ucd09\uc9c4\ud558\uc5ec \ud3ec\ub3c4\ub2f9 \ub300\uc0ac \ud6a8\uc728\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \uc774\ub97c \ud1b5\ud574 \uc804\uc790 \uc804\ub2ec\uacc4\uac00 \ub354\uc6b1 \uc6d0\ud65c\ud558\uac8c \uc791\ub3d9\ud558\uace0 ATP \uc0dd\uc131 \ud6a8\uc728\uc774 \uc99d\uac00\ud569\ub2c8\ub2e4. \ubc15\ud14c\ub9ac\uc544 \ubaa8\ub378\uc5d0\uc11c PQQ\ub294 \uc804\uc790 \uc804\ub2ec\uacc4\uc758 \ud575\uc2ec \ubcf4\uc870 \uc778\uc790\ub85c \uc791\uc6a9\ud558\uc5ec \ubc15\ud14c\ub9ac\uc544\uc758 \uc5d0\ub108\uc9c0 \ub300\uc0ac\ub97c \uc720\uc9c0\ud558\ub294 \ub370 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc778\uac04 \uc138\ud3ec\uc5d0\uc11c\ub3c4 PQQ\ub294 \uc804\uc790 \uc804\ub2ec\uacc4\uc758 \uae30\ub2a5\uc744 \ucd5c\uc801\ud654\ud558\uc5ec \uc138\ud3ec\uc5d0 \ub354 \ub9ce\uc740 \uc5d0\ub108\uc9c0\ub97c \uacf5\uae09\ud558\uace0 \uc815\uc0c1\uc801\uc778 \uc138\ud3ec \ud65c\ub3d9\uc744 \ubcf4\uc7a5\ud569\ub2c8\ub2e4.<\/p>\n

(III) \ub2e4\uba74\uc801 \uac74\uac15 \uc9c0\uc6d0<\/h3>\n

1. \uc2ec\ud608\uad00\uacc4\uc758 \ub4e0\ub4e0\ud55c \ubc29\ud328<\/h4>\n

\uc2ec\ud608\uad00\uacc4\ub294 \uc778\uccb4\uc758 “\uc6b4\uc1a1\ub9dd”\uacfc \uac19\uc2b5\ub2c8\ub2e4. \uc2ec\uc7a5\uc740 \uc774 \ub124\ud2b8\uc6cc\ud06c\uc758 “\ud30c\uc6cc \ud38c\ud504”\uc774\uace0 \ud608\uad00\uc740 \uc2e0\uccb4\uc758 \ubaa8\ub4e0 \uc870\uc9c1\uacfc \uae30\uad00\uc5d0 \uc0b0\uc18c\uc640 \uc601\uc591\uc18c\ub97c \uc6b4\ubc18\ud558\uace0 \ud608\uc561\uc744 \uc720\uc9c0\ud558\ub294 \uc5ed\ud560\uc744 \ud558\ub294 \uad50\ucc28\ud558\ub294 “\ub3c4\ub85c”\uc785\ub2c8\ub2e4 \uc815\uc0c1\uc801\uc778 \uc0dd\ub9ac \uae30\ub2a5\uc744 \uc800\ud558\uc2dc\ud0b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uace0\uc5fc, \uace0\uc9c0\ubc29 \uc2dd\ub2e8, \uc6b4\ub3d9 \ubd80\uc871, \ub9cc\uc131\uc801\uc778 \uc815\uc2e0\uc801 \uc2a4\ud2b8\ub808\uc2a4, \ub178\ud654\uc640 \uac19\uc740 \ud604\ub300 \uc0dd\ud65c\uc758 \uac74\uac15\uc5d0 \ud574\ub85c\uc6b4 \uc2b5\uad00\uc740 \uc2ec\ud608\uad00\uacc4\ub97c \uc190\uc0c1\uc2dc\ucf1c \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\uc99d, \uad00\uc0c1\ub3d9\ub9e5 \uc2ec\uc7a5 \uc9c8\ud658, \uace0\ud608\uc555\uacfc \uac19\uc740 \uc77c\ub828\uc758 \uc2ec\ud608\uad00 \uc9c8\ud658\uc744 \uc720\ubc1c\ud558\uc5ec \uc0ac\ub78c\ub4e4\uc758 \uac74\uac15\uacfc \uc0dd\uba85\uc744 \uc2ec\uac01\ud558\uac8c \uc704\ud611\ud569\ub2c8\ub2e4.<\/p>\n

PQQ\ub294 \ub2e4\uc591\ud55c \uc791\uc6a9 \uae30\uc804\uc744 \ud1b5\ud574 \uc2ec\ud608\uad00 \uac74\uac15\uc744 \ubcf4\ud638\ud558\ub294 \ub370 \ud0c1\uc6d4\ud569\ub2c8\ub2e4. \uccab\uc9f8, PQQ\uc758 \uac15\ub825\ud55c \ud56d\uc0b0\ud654 \ub2a5\ub825\uc740 \ud608\uad00 \ub0b4 \ud65c\uc131\uc0b0\uc18c\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \uc81c\uac70\ud558\uc5ec \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub85c \uc778\ud55c \ub0b4\ud53c \uc138\ud3ec \uc190\uc0c1\uc744 \uc904\uc785\ub2c8\ub2e4. \ub0b4\ud53c \uc138\ud3ec\ub294 \ud608\uad00\uc744 \ubcf4\ud638\ud558\ub294 \ub9c9\uacfc \uac19\uc740 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc190\uc0c1\ub418\uba74 \ud608\uad00 \ud22c\uacfc\uc131\uc774 \uc99d\uac00\ud558\uc5ec \ud608\uc561 \ub0b4 \uc9c0\uc9c8\uc774 \ud608\uad00 \ubcbd\uc5d0 \uce68\ucc29\ub418\uc5b4 \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\ubc18\uc744 \ud615\uc131\ud558\uae30 \uc27d\uc2b5\ub2c8\ub2e4. PQQ\ub294 \ud65c\uc131\uc0b0\uc18c\ub97c \uc81c\uac70\ud558\uace0, \uc0b0\ud654\ub41c \uc800\ubc00\ub3c4 \uc9c0\ub2e8\ubc31\uc9c8(LDL)\uc758 \uc0b0\ud654\ub97c \uc904\uc774\uba70, \uc9c0\uc9c8 \uacfc\uc0b0\ud654\ub97c \uc5b5\uc81c\ud558\uc5ec \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\uc99d\uc758 \uc704\ud5d8\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \uc2dc\ud5d8\uad00 \ub0b4 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 PQQ\ub294 LDL\uc758 \uc0b0\ud654\uc801 \ubcc0\ud615\uc744 \ud604\uc800\ud788 \uac10\uc18c\uc2dc\ud0a4\uace0 \uc0b0\ud654\ub41c LDL\uc774 \ud608\uad00 \ub0b4\ud53c \uc138\ud3ec\uc5d0 \uc190\uc0c1\uc744 \uc785\ud788\ub294 \uac83\uc744 \uc5b5\uc81c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

PQQ\ub294 \ub610\ud55c \ud56d\uc5fc\uc99d \ud2b9\uc131\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc5fc\uc99d\uc740 \uc2ec\ud608\uad00 \uc9c8\ud658 \ubc1c\uc0dd\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc5fc\uc99d\uc740 \ud608\uad00\ubcbd\uc758 \uc5fc\uc99d \uc138\ud3ec \uce68\uc724\uc744 \uc720\ub3c4\ud558\uace0, \uc8fd\uc0c1\uacbd\ud654\ubc18\uc758 \ud615\uc131 \ubc0f \uc9c4\ud589\uc744 \ucd09\uc9c4\ud558\uba70, \uc8fd\uc0c1\uacbd\ud654\ubc18 \ud30c\uc5f4 \uc704\ud5d8\uc744 \uc99d\uac00\uc2dc\ud0a4\uace0, \uad81\uadf9\uc801\uc73c\ub85c \uae09\uc131 \uc2ec\ud608\uad00 \uc9c8\ud658\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4. PQQ\ub294 \uc885\uc591\uad34\uc0ac\uc778\uc790-\u03b1(TNF-\u03b1) \ubc0f \uc778\ud130\ub8e8\ud0a8-6(IL-6)\uacfc \uac19\uc740 \uc5fc\uc99d \uc778\uc790\uc758 \uc0dd\uc131\uc744 \uc5b5\uc81c\ud558\uc5ec \ub9cc\uc131 \uc5fc\uc99d\uc744 \uc644\ud654\ud558\uace0 \uc2ec\ud608\uad00 \uc870\uc9c1\uc744 \uc5fc\uc99d \uc190\uc0c1\uc73c\ub85c\ubd80\ud130 \ubcf4\ud638\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc784\uc0c1 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 PQQ \ubcf4\ucda9\uc81c\ub294 \ub9cc\uc131 \uc5fc\uc99d \ud658\uc790\uc758 IL-6 \uc218\uce58\ub97c \uc57d 27% \uac10\uc18c\uc2dc\ucf1c \uc5fc\uc99d \uac10\uc18c\uc5d0 \uc0c1\ub2f9\ud55c \ud6a8\uacfc\ub97c \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \ub610\ud55c, PQQ\ub294 \uc2ec\uadfc\uc138\ud3ec \ub0b4 \uc5d0\ub108\uc9c0 \ub300\uc0ac\ub97c \uac1c\uc120\ud558\uace0 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ub9c9 \uc804\uc704\ub97c \uc870\uc808\ud558\uace0, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ud638\ud761 \uc0ac\uc2ac \ud6a8\uc18c\uc758 \ud65c\uc131\uc744 \ucd09\uc9c4\ud558\uba70, \uae30\ud0c0 \uacbd\ub85c\ub97c \ud1b5\ud574 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub85c \uc778\ud55c \uc2ec\uadfc\uc138\ud3ec \uc190\uc0c1\uc744 \uc644\ud654\ud558\uace0 \uc2ec\uc7a5 \uae30\ub2a5\uc744 \ubcf4\ud638\ud568\uc73c\ub85c\uc368 \uc2ec\uadfc\uc138\ud3ec\uc758 \ud56d\uc0b0\ud654 \ub2a5\ub825\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \ub3d9\ubb3c \uc5f0\uad6c\uc5d0\uc11c PQQ \ud22c\uc5ec\ub294 \uc2ec\uc7a5 \uc555\ub825 \uacfc\ubd80\ud558\ub85c \uc778\ud55c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc7a5\uc560\ub97c \uc608\ubc29\ud558\uace0, \uc2ec\uc7a5 \ub9ac\ubaa8\ub378\ub9c1 \ubc0f \uc138\ud3ec \ube44\ub300\ub97c \uac1c\uc120\ud558\uba70, \uc2ec\uadfc\uacbd\uc0c9\uc758 \ud06c\uae30\ub97c \uac10\uc18c\uc2dc\ud0a4\uace0, \ub9cc\uc131 \uc2ec\ubd80\uc804 \ubc1c\uc0dd\uc744 \uc608\ubc29\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n

2. \uc2e0\uacbd\uacc4\ub97c \uc704\ud55c \ubd80\ub4dc\ub7ec\uc6b4 \ubcf4\ud638<\/h4>\n

\uc2e0\uacbd\uacc4\ub294 \ub2e4\uc591\ud55c \uc815\ubcf4\ub97c \uc218\uc2e0, \ucc98\ub9ac \ubc0f \uc804\ub2ec\ud558\uace0, \uc0dd\ub9ac \ud65c\ub3d9\uacfc \ud589\ub3d9\uc744 \uc870\uc808\ud558\ub294 \uc2e0\uccb4\uc758 “\uc9c0\ud718 \uc13c\ud130”\uc785\ub2c8\ub2e4. \uc2e0\uacbd\uacc4\uc758 \uae30\ubcf8 \uad6c\uc131 \uc694\uc18c\uc778 \ub274\ub7f0\uc740 \ub9e4\uc6b0 \ucde8\uc57d\ud558\uba70 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \ubc0f \uc5fc\uc99d\uacfc \uac19\uc740 \uc694\uc778\uc73c\ub85c \uc778\ud574 \uc190\uc0c1\ub418\uae30 \uc27d\uc2b5\ub2c8\ub2e4. \uc2e0\uacbd \uc138\ud3ec \uc190\uc0c1\uc740 \uc2e0\uacbd \uae30\ub2a5 \uc7a5\uc560\uc640 \uc54c\uce20\ud558\uc774\uba38\ubcd1, \ud30c\ud0a8\uc2a8\ubcd1, \uc6b0\uc6b8\uc99d\uacfc \uac19\uc740 \ub2e4\uc591\ud55c \uc2e0\uacbd \uc9c8\ud658\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc73c\uba70, \uc774\ub294 \ud658\uc790\uc758 \uc0b6\uc758 \uc9c8\uc5d0 \uc911\ub300\ud55c \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4.<\/p>\n

PQQ\ub294 \uc2e0\uacbd\uacc4\uc5d0 \ud3ec\uad04\uc801\uc778 \ubcf4\ud638 \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \uac15\ub825\ud55c \ud56d\uc0b0\ud654 \ubc0f \ud56d\uc5fc\uc99d \ud6a8\uacfc\ub294 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc640 \uc5fc\uc99d\uc73c\ub85c \uc778\ud55c \uc2e0\uacbd \uc138\ud3ec \uc190\uc0c1\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658\uc758 \ubc1c\ubcd1 \uacfc\uc815\uc5d0\uc11c \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc640 \uc5fc\uc99d\uc740 \uc2e0\uacbd \uc138\ud3ec \ub0b4 \ub2e8\ubc31\uc9c8\uc758 \uc624\uc811\ud798\uacfc \uc751\uc9d1\uc744 \uc720\ubc1c\ud558\uc5ec \uc2e0\uacbd\uc12c\uc720 \uc5c9\ud0b4\uacfc \uc544\ubc00\ub85c\uc774\ub4dc \ud50c\ub77c\ud06c\ub97c \ud615\uc131\ud558\uace0, \uad81\uadf9\uc801\uc73c\ub85c \uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78\uc744 \ucd08\ub798\ud569\ub2c8\ub2e4. PQQ\ub294 \uc790\uc720 \ub77c\ub514\uce7c\uc744 \uc81c\uac70\ud558\uace0 \uc5fc\uc99d \uc778\uc790 \uc0dd\uc131\uc744 \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc774\ub7ec\ud55c \ubcd1\ub9ac\ud559\uc801 \ubcc0\ud654\ub97c \uc644\ud654\ud558\uc5ec \uc2e0\uacbd \uc138\ud3ec\ub97c \uc190\uc0c1\uc73c\ub85c\ubd80\ud130 \ubcf4\ud638\ud569\ub2c8\ub2e4. \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ubaa8\ub378\uc5d0\uc11c PQQ\ub294 \uc0dd\uc950 \ub1cc\uc758 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \uc9c0\ud45c\uc778 MDA \uc218\uce58\ub97c \uac10\uc18c\uc2dc\ud0a4\uace0, \uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78\uc744 \uac10\uc18c\uc2dc\ud0a4\uba70, \uacf5\uac04 \uae30\uc5b5\ub825\uc744 \ud5a5\uc0c1\uc2dc\ucf30\uc2b5\ub2c8\ub2e4.<\/p>\n

PQQ\ub294 \ub610\ud55c \uc2e0\uacbd \uc131\uc7a5 \uc778\uc790(NGF)\uc758 \ud569\uc131\uacfc \ubd84\ube44\ub97c \ucd09\uc9c4\ud569\ub2c8\ub2e4. NGF\ub294 \ub274\ub7f0\uc758 \uc131\uc7a5, \ubc1c\ub2ec, \uc0dd\uc874 \ubc0f \uae30\ub2a5\uc5d0 \ud544\uc218\uc801\uc778 \ub2e8\ubc31\uc9c8\uc785\ub2c8\ub2e4. \ub274\ub7f0\uc758 “\uc601\uc591\uc18c” \uc5ed\ud560\uc744 \ud558\uc5ec \uc131\uc7a5, \ubd84\ud654 \ubc0f \ubcf5\uad6c\ub97c \ucd09\uc9c4\ud558\uace0 \ub274\ub7f0 \uac04 \uc5f0\uacb0 \ubc0f \uc2e0\ud638 \uc804\ub2ec\uc744 \uac15\ud654\ud569\ub2c8\ub2e4. PQQ\ub294 \uc131\uc0c1\uc138\ud3ec\uc640 \uc12c\uc720\uc544\uc138\ud3ec\uc5d0\uc11c NGF\uc758 \ud569\uc131 \ubc0f \ubd84\ube44\ub97c \uc790\uadf9\ud558\uc5ec \uc138\ud3ec \ub3c5\uc131 \uc5c6\uc774 NGF \uc0dd\uc131\uc744 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4. \uc784\uc0c1 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc77c\uc815 \uc6a9\ub7c9\uc758 PQQ\ub97c \uc77c\uc815 \uae30\uac04 \ub3d9\uc548 \ub9e4\uc77c \uacbd\uad6c \ud22c\uc5ec\ud558\uba74 \ud53c\ub85c, \ubd88\uc548, \uc6b0\uc6b8\uc99d, \ubd84\ub178, \ud63c\ub780\uacfc \uac19\uc740 \ucc38\uac00\uc790\uc758 \uc815\uc2e0 \uc0c1\ud0dc\ub97c \uac1c\uc120\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub420 \ubfd0\ub9cc \uc544\ub2c8\ub77c \uc218\uba74 \uc2dc\uac04\uacfc \uac01\uc131 \uc0c1\ud0dc\ub97c \uac1c\uc120\ud558\uc5ec \uc218\uba74\uc758 \uc9c8\uc744 \ud06c\uac8c \ud5a5\uc0c1\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc774\ub294 PQQ\uac00 NGF \uc0dd\uc131\uc744 \ucd09\uc9c4\ud558\uace0 \uc2e0\uacbd\uacc4 \uae30\ub2a5\uc744 \uac1c\uc120\ud558\ub294 \ub2a5\ub825\uacfc \uad00\ub828\uc774 \uc788\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

3. \ub300\uc0ac \uc870\uc808\uc5d0 \uac15\ub825\ud55c \ub3c4\uc6c0<\/h4>\n

\ud604\ub300 \uc0ac\ud68c\uc5d0\uc11c\ub294 \uace0\uce7c\ub85c\ub9ac \uc2dd\ub2e8\uacfc \uc2e0\uccb4 \ud65c\ub3d9 \uac10\uc18c\uc640 \uac19\uc740 \uc0dd\ud65c \uc2b5\uad00 \ubcc0\ud654\ub85c \uc778\ud574 \ub300\uc0ac \uc9c8\ud658 \ubc1c\uc0dd\ub960\uc774 \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4 \ube44\ub9cc\uacfc \ub2f9\ub1e8\ubcd1\uacfc \uac19\uc740 \ub300\uc0ac \uc9c8\ud658\uc774 \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc9c8\ud658\uc740 \ud658\uc790\uc758 \uc2e0\uccb4 \uac74\uac15\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \ubfd0\ub9cc \uc544\ub2c8\ub77c \uc2ec\ud608\uad00 \uc9c8\ud658, \uc2e0\uc7a5 \uc9c8\ud658\uacfc \uac19\uc740 \ud569\ubcd1\uc99d \uc704\ud5d8\uc744 \uc99d\uac00\uc2dc\ucf1c \uac1c\uc778\uacfc \uc0ac\ud68c\uc5d0 \ud070 \ubd80\ub2f4\uc744 \uc8fc\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

PQQ\ub294 \uc2e0\uc9c4\ub300\uc0ac \uc870\uc808\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\uba70 \ube44\ub9cc\uacfc \ub2f9\ub1e8\ubcd1\uacfc \uac19\uc740 \ub300\uc0ac \uc9c8\ud658 \uac1c\uc120\uc5d0 \uae0d\uc815\uc801\uc778 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ube44\ub9cc\uacfc \uad00\ub828\ud558\uc5ec, PQQ\ub294 \ub2e4\uc591\ud55c \uba54\ucee4\ub2c8\uc998\uc744 \ud1b5\ud574 \uccb4\uc9c0\ubc29 \ucd95\uc801\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uccab\uc9f8, PQQ\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5\uc744 \ud06c\uac8c \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \uc9c0\uc9c8 \ub300\uc0ac \uacfc\uc815\uc778 \ubca0\ud0c0 \uc0b0\ud654\ub97c \uac1c\uc120\ud558\uc5ec \uc9c0\ubc29\uc744 \uc5d0\ub108\uc9c0\ub85c \ub354\uc6b1 \ud6a8\uc728\uc801\uc73c\ub85c \ubd84\ud574\ud560 \uc218 \uc788\ub3c4\ub85d \ud569\ub2c8\ub2e4. \uc774\ub294 \uc9c0\ubc29 \uc0dd\uc131\uc744 \uc5b5\uc81c\ud558\uace0 \uccb4\uc9c0\ubc29 \ucd95\uc801\uc744 \uac10\uc18c\uc2dc\ud0a4\uba70, \ud2b9\ud788 \uac04 \uc9c0\ubc29\uacfc \uac19\uc740 \ub0b4\uc7a5 \uc9c0\ubc29\uc758 \ucd95\uc801\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ube44\ub9cc \ub9c8\uc6b0\uc2a4 \ubaa8\ub378\uc5d0\uc11c PQQ \ubcf4\ucda9\uc740 \uccb4\uc911, \ub0b4\uc7a5 \uc9c0\ubc29 \ud568\ub7c9, \uc9c0\ubc29\uc138\ud3ec \ud06c\uae30\ub97c \ud604\uc800\ud788 \uac10\uc18c\uc2dc\ucf30\uc2b5\ub2c8\ub2e4.<\/p>\n

PQQ\ub294 \ub610\ud55c \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uccd0 \uc2e0\uc9c4\ub300\uc0ac\ub97c \uc870\uc808\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70 \uad6c\uc131\uc740 \ube44\ub9cc \uc704\ud5d8\uacfc \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. PQQ\ub294 \ud2b9\uc815 \uc720\uc775\uade0\uc758 \uc591\uc744 \ub298\ub9ac\uace0, \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\ucd1d\uc744 \uac1c\uc120\ud558\uba70, \ube44\ub9cc \uad00\ub828 \uc5fc\uc99d \uc9c0\ud45c\ub97c \uac10\uc18c\uc2dc\ucf1c \ube44\ub9cc \uc704\ud5d8\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c, PQQ\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc7a5\uc560\uc640 \uc5fc\uc99d\uc744 \uc644\ud654\ud558\uace0, \ube44\uc54c\ucf54\uc62c\uc131 \uc9c0\ubc29\uac04\uc5fc, \ub9cc\uc131 \uc2e0\uc7a5 \uc9c8\ud658, \uc81c2\ud615 \ub2f9\ub1e8\ubcd1\uc744 \ud3ec\ud568\ud55c \ube44\ub9cc \uad00\ub828 \ub300\uc0ac \uc9c8\ud658\uc758 \uc9c4\ud589\uc744 \uac1c\uc120\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc81c2\ud615 \ub2f9\ub1e8\ubcd1 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c PQQ\ub294 \uc778\uc290\ub9b0 \ubbfc\uac10\uc131\uc744 \uac1c\uc120\ud558\uace0, \ud608\ub2f9 \uc218\uce58\ub97c \ub0ae\ucd94\uba70, \ube44\uc815\uc0c1\uc801\uc778 \ud3ec\ub3c4\ub2f9 \ub300\uc0ac\ub97c \uac1c\uc120\ud558\ub294 \ud6a8\uacfc\uac00 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c \ub2f9\ub1e8\ubcd1\uc73c\ub85c \uc778\ud55c \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc640 \uc5fc\uc99d\uc744 \uc904\uc774\uace0, \ucdcc\uc7a5 \ubca0\ud0c0 \uc138\ud3ec \uae30\ub2a5\uc744 \ubcf4\ud638\ud558\uba70, \ub2f9\ub1e8\ubcd1 \ud569\ubcd1\uc99d\uc758 \ubc1c\ubcd1\uc744 \uc9c0\uc5f0\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

4. \uba74\uc5ed \uccb4\uacc4 \uac15\ud654<\/h4>\n

\uba74\uc5ed \uccb4\uacc4\ub294 \uce68\uc785\ud558\ub294 \ubcd1\uc6d0\uade0\uc5d0 \ub300\ud55c \uc2e0\uccb4\uc758 \ubc29\uc5b4\ub825\uc785\ub2c8\ub2e4. \uba74\uc5ed \uae30\uad00, \uba74\uc5ed \uc138\ud3ec, \uba74\uc5ed \ubd84\uc790\ub85c \uad6c\uc131\ub41c \uba74\uc5ed \uccb4\uacc4\ub294 \ubc15\ud14c\ub9ac\uc544, \ubc14\uc774\ub7ec\uc2a4, \uacf0\ud321\uc774\uc640 \uac19\uc740 \uc678\ubd80 \ubcd1\uc6d0\uade0\uacfc \uccb4\ub0b4 \ub3cc\uc5f0\ubcc0\uc774 \uc138\ud3ec\ub97c \uc2dd\ubcc4\ud558\uace0 \uc81c\uac70\ud558\uc5ec \uac74\uac15\uc744 \uc720\uc9c0\ud569\ub2c8\ub2e4. \uba74\uc5ed \uccb4\uacc4\uac00 \uc57d\ud654\ub418\uba74 \uc2e0\uccb4\ub294 \ub2e4\uc591\ud55c \ubcd1\uc6d0\uade0\uc5d0 \ucde8\uc57d\ud574\uc838 \uac10\uc5fc\uc131 \uc9c8\ud658\uacfc \uc7a5\uae30\uac04\uc758 \ud68c\ubcf5\uc73c\ub85c \uc774\uc5b4\uc9d1\ub2c8\ub2e4.<\/p>\n

PQQ\ub294 \uc5ec\ub7ec \uc218\uc900\uc5d0\uc11c \uba74\uc5ed\ub825\uc744 \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc138\ud3ec \uc218\uc900\uc5d0\uc11c PQQ\ub294 \uba74\uc5ed \uc138\ud3ec\uc758 \uc99d\uc2dd\uacfc \ubd84\ud654\ub97c \ucd09\uc9c4\ud558\uc5ec \ud65c\uc131\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, T \ub9bc\ud504\uad6c\uc640 B \ub9bc\ud504\uad6c\uc758 \uc99d\uc2dd\uc744 \uc790\uadf9\ud558\uc5ec \uba74\uc5ed \ubc29\uc5b4 \uae30\ub2a5\uc744 \ub354\uc6b1 \ud6a8\uacfc\uc801\uc73c\ub85c \uc218\ud589\ud560 \uc218 \uc788\ub3c4\ub85d \ud569\ub2c8\ub2e4. T \ub9bc\ud504\uad6c\ub294 \uc138\ud3ec \uba74\uc5ed\uc5d0\uc11c \ud575\uc2ec\uc801\uc778 \uc5ed\ud560\uc744 \ud558\uba70, \ubcd1\uc6d0\uade0\uc5d0 \uac10\uc5fc\ub41c \uc138\ud3ec\uc640 \uc885\uc591 \uc138\ud3ec\ub97c \uc778\uc2dd\ud558\uace0 \uc0ac\uba78\uc2dc\ud0b5\ub2c8\ub2e4. B \ub9bc\ud504\uad6c\ub294 \uc8fc\ub85c \uccb4\uc561 \uba74\uc5ed\uc5d0 \uad00\uc5ec\ud558\uc5ec \ubcd1\uc6d0\uade0\uacfc \uadf8 \ub3c5\uc18c\ub97c \uc911\ud654\ud558\ub294 \ud56d\uccb4\ub97c \uc0dd\uc131\ud569\ub2c8\ub2e4. PQQ\ub294 T \ub9bc\ud504\uad6c\uc640 B \ub9bc\ud504\uad6c\uc758 \uae30\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0b4\uc73c\ub85c\uc368 \uc138\ud3ec \uba74\uc5ed\uacfc \uccb4\uc561 \uba74\uc5ed\uc744 \ubaa8\ub450 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \ub610\ud55c PQQ\ub294 \uba74\uc5ed \uc138\ud3ec \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc870\uc808\ud558\uace0 \uae30\ub2a5\uc744 \ucd5c\uc801\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uba74\uc5ed \uc138\ud3ec\uac00 \ubcd1\uc6d0\uade0\uc744 \uc778\uc2dd\ud558\uba74 \ubcf5\uc7a1\ud55c \uc77c\ub828\uc758 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \ud65c\uc131\ud654\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub294 \uc138\ud3ec \ub0b4\uc5d0\uc11c “\uc2e0\ud638 \uace0\uc18d\ub3c4\ub85c”\ucc98\ub7fc \uc791\uc6a9\ud558\uc5ec \uba74\uc5ed \uc2e0\ud638\ub97c \uc804\ub2ec\ud558\uace0 \uba74\uc5ed \uc138\ud3ec\uc758 \ud65c\uc131\ud654, \uc99d\uc2dd \ubc0f \ud6a8\uacfc\uae30 \uae30\ub2a5\uc744 \uc870\uc808\ud569\ub2c8\ub2e4. PQQ\ub294 NF-\u03baB(\ud575\uc778\uc790 \u03baB)\uc640 \uac19\uc740 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc758 \ud575\uc2ec \ubd84\uc790\ub97c \u200b\u200b\uc870\uc808\ud558\uc5ec \uba74\uc5ed \uc138\ud3ec\uac00 \ubcd1\uc6d0\uade0\uc5d0 \ub354\uc6b1 \uc815\ud655\ud558\uace0 \ud6a8\uacfc\uc801\uc73c\ub85c \ubc18\uc751\ud558\ub3c4\ub85d \ud558\uc5ec \uba74\uc5ed \ubc29\uc5b4\ub825\uc744 \uac15\ud654\ud569\ub2c8\ub2e4. \uc784\uc0c1 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 PQQ \ubcf4\ucda9\uc81c\ub294 \uba74\uc5ed \uccb4\uacc4\uac00 \uc57d\ud654\ub41c \uc77c\ubd80 \uc0ac\ub78c\ub4e4\uc5d0\uac8c\uc11c \uac10\uae30\ub098 \ub3c5\uac10\uacfc \uac19\uc740 \uac10\uc5fc\uc131 \uc9c8\ud658\uc758 \ubc1c\ubcd1\ub960\uc744 \ud604\uc800\ud788 \uac10\uc18c\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc9c8\ubcd1 \ud6c4 \uc99d\uc0c1\ub3c4 \uc644\ud654\ub418\uace0 \ud68c\ubcf5 \uae30\uac04\ub3c4 \ub2e8\ucd95\ub418\uc5b4 PQQ\uc758 \uba74\uc5ed\ub825 \uc99d\uac15 \ud6a8\uacfc\ub97c \uc785\uc99d\ud569\ub2c8\ub2e4.<\/p>\n

PQQ\uc758 \uc5f0\uad6c \uc9c4\ud589 \uc0c1\ud669 \ubc0f \uc751\uc6a9 \ubd84\uc57c<\/h2>\n

\"\"<\/p>\n

(I) \uc0c8\ub85c\uc6b4 \uacfc\ud559\uc801 \ub3cc\ud30c\uad6c<\/h3>\n

\ucd5c\uadfc \uba87 \ub144 \ub3d9\uc548 PQQ\ub294 \uacfc\ud559 \uc5f0\uad6c\uc5d0\uc11c \uc218\ub9ce\uc740 \ub180\ub77c\uc6b4 \uc131\uacfc\ub97c \uac70\ub450\uba70 \uadf8 \ud6a8\ub2a5\uacfc \uc751\uc6a9 \ubd84\uc57c\uc5d0 \ub300\ud55c \uc6b0\ub9ac\uc758 \uc774\ud574\ub97c \ub4b7\ubc1b\uce68\ud558\ub294 \uacfc\ud559\uc801 \uc99d\uac70\ub97c \uc81c\uc2dc\ud588\uc2b5\ub2c8\ub2e4. \ub178\ud654 \ubc29\uc9c0\uc640 \uad00\ub828\ud558\uc5ec, By-Health\uc640 \uc911\uad6d\uacfc\ud559\uc6d0 \uc0c1\ud558\uc774 \uc601\uc591\uac74\uac15\uc5f0\uad6c\uc18c\uac00 \uacf5\ub3d9\uc73c\ub85c \uc218\ud589\ud558\uc5ec \uad6d\uc81c\uc801\uc73c\ub85c \uc778\uc815\ubc1b\ub294 \ud559\uc220\uc9c0\uc778 Aging Cell\uc5d0 \uac8c\uc7ac\ub41c \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74, PQQ\ub294 “\ub0b4\uc778\uc131 \ub178\ud654”\uc5d0 \uae30\uc5ec\ud558\ub294 \uc720\ud574 \uc694\uc778\uc778 \ub178\ud654 \uad00\ub828 \ubd84\ube44 \ud45c\ud604\ud615(SASP)\uc744 \uac10\uc18c\uc2dc\ud0a4\uace0, \ub178\ud654 \uc138\ud3ec \ub0b4 \uc790\uc720 \ub77c\ub514\uce7c\uc744 \ud604\uc800\ud788 \uac10\uc18c\uc2dc\ud0a4\uba70, \ub178\ud654 \ub9c8\uc6b0\uc2a4\uc758 \uc5ec\ub7ec \uc7a5\uae30\uc5d0\uc11c \ub9cc\uc131 \uc5fc\uc99d\uc744 \uc644\ud654\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc774 \uc5f0\uad6c\ub294 PQQ\uac00 \ub178\ud654\ub97c \uc9c0\uc5f0\uc2dc\ud0a4\uace0 \uc804\ubc18\uc801\uc778 \uac74\uac15\uc744 \uc720\uc9c0\ud558\ub294 \ub370 \ud6a8\uacfc\uc801\uc778 \uc131\ubd84\uc784\uc744 \uac15\ub825\ud558\uac8c \uc785\uc99d\ud558\uba70, \uc548\uc804\ud558\uace0 \ud6a8\uacfc\uc801\uc778 \ucc9c\uc5f0 \ub178\ud654 \ubc29\uc9c0 \ubb3c\uc9c8\uc5d0 \ub300\ud55c \ubbf8\ub798 \uc5f0\uad6c\ub97c \uc704\ud55c \uc0c8\ub85c\uc6b4 \uae38\uc744 \uc5f4\uc5b4\uc90d\ub2c8\ub2e4.<\/p>\n

\uc778\uc9c0 \uae30\ub2a5 \ud5a5\uc0c1\uacfc \uad00\ub828\ud558\uc5ec, \uc77c\ubcf8 \uc5f0\uad6c\uc9c4\uc774 2023\ub144 2\uc6d4 Food & Function \ud559\uc220\uc9c0\uc5d0 \ubc1c\ud45c\ud55c \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 PQQ\ub294 \uc80a\uc740 \uc77c\ubcf8\uc778\uacfc \ub178\ub144 \uc77c\ubcf8\uc778 \ubaa8\ub450\uc758 \uc778\uc9c0 \uae30\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0a8\ub2e4\ub294 \uac83\uc774 \uc785\uc99d\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774 \uc774\uc911\ub9f9\uac80, \uc704\uc57d\ub300\uc870, \ubb34\uc791\uc704 \ubc30\uc815 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\ub294 20\uc138\uc5d0\uc11c 65\uc138 \uc0ac\uc774\uc758 \uac74\uac15\ud55c \ub0a8\ub140 62\uba85\uc774 \ucc38\uc5ec\ud588\uc2b5\ub2c8\ub2e4. \ucc38\uac00\uc790\ub4e4\uc740 12\uc8fc \ub3d9\uc548 \ub9e4\uc77c 20mg\uc758 PQQ\ub97c \uacbd\uad6c \ubcf5\uc6a9\ud558\uac70\ub098 \uc704\uc57d \ucea1\uc290\uc744 \ubcf5\uc6a9\ud588\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c \uacb0\uacfc, PQQ \uc12d\ucde8\ub294 \uc77c\ubc18 \uc778\uad6c\uc640 \ub178\uc778 \ubaa8\ub450\uc5d0\uc11c \ubcf5\ud569 \uae30\uc5b5\ub825 \ubc0f \uc5b8\uc5b4 \uae30\uc5b5\ub825 \uc810\uc218\ub97c \ud5a5\uc0c1\uc2dc\ucf30\uc73c\uba70, \uc80a\uc740 \ucc38\uac00\uc790\ub4e4\uc740 \uc778\uc9c0 \uc720\uc5f0\uc131, \ucc98\ub9ac \uc18d\ub3c4, \uc2e4\ud589 \uc18d\ub3c4\uc5d0\uc11c\ub3c4 \ud5a5\uc0c1\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uac19\uc740 \ud574 3\uc6d4, \uad6d\uc81c\uc801\uc73c\ub85c \uc800\uba85\ud55c \ud559\uc220\uc9c0\uc778 Food & Function\uc5d0 \uac8c\uc7ac\ub41c \ub610 \ub2e4\ub978 \uc5f0\uad6c\uc5d0\uc11c\ub294 PQQ\uac00 \ubaa8\ub4e0 \uc5f0\ub839\ub300\uc758 \uc778\uc9c0 \uae30\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \ucd94\uac00\ub85c \uc785\uc99d\ud588\uc73c\uba70, \uc774\ub294 \ub178\uc778\uc744 \ub118\uc5b4 \ubaa8\ub4e0 \uc5f0\ub839\ub300\ub85c \uae30\ub2a5\uc131 \uc2dd\ud488\uc73c\ub85c\uc11c\uc758 \ud65c\uc6a9\uc744 \ud655\ub300\ud560 \uc218 \uc788\ub294 \uc7a0\uc7ac\ub825\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

PQQ\ub294 \uc9c8\ubcd1 \uc608\ubc29\uc5d0\ub3c4 \uc0c1\ub2f9\ud55c \uc7a0\uc7ac\ub825\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. 2023\ub144 9\uc6d4, Aging Cell\uc5d0 \uc628\ub77c\uc778\uc73c\ub85c \uac8c\uc7ac\ub41c \ud55c \uc5f0\uad6c\uc5d0\uc11c\ub294 \ub9c8\uc6b0\uc2a4 \uc2e4\ud5d8\uc744 \ud1b5\ud574 \uc2dd\uc774 PQQ \ubcf4\ucda9\uc81c\uac00 \uc790\uc5f0 \ub178\ud654\uc640 \uad00\ub828\ub41c \uc9c8\ud658\uc778 \uace8\ub2e4\uacf5\uc99d\uc744 \uc608\ubc29\ud560 \uc218 \uc788\uc74c\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 PQQ\ub294 \uc870\uace8\uc138\ud3ec\uc5d0\uc11c MCM3-Keap1-Nrf2 \uc2e0\ud638\uc804\ub2ec\uc744 \ud65c\uc131\ud654\ud558\uc5ec \ud56d\uc0b0\ud654 \uc720\uc804\uc790\uc640 Fbn1 \uc720\uc804\uc790\uc758 \ubc1c\ud604\uc744 \uc804\uc0ac\uc801\uc73c\ub85c \uc0c1\ud5a5\uc870\uc808\ud558\uace0, \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc640 \ud30c\uace8\uc138\ud3ec\uc758 \uace8 \ud761\uc218\ub97c \uc5b5\uc81c\ud558\uba70, \uc870\uace8\uc138\ud3ec\uc758 \uace8 \ud615\uc131\uc744 \ucd09\uc9c4\ud558\uc5ec \uc5f0\ub839 \uad00\ub828 \uace8\ub2e4\uacf5\uc99d \uc608\ubc29\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uac19\uc740 \ub2ec, \uc720\ub7fd\uc758 \ud55c \uc720\uba85 \uc758\uacfc\ub300\ud559\uc5d0\uc11c Acta Neuropathol Commun \uc800\ub110\uc5d0 \ubc1c\ud45c\ud55c \uc5f0\uad6c\uc5d0\uc11c\ub294 PQQ\uac00 \ub9dd\ub9c9 \uc2e0\uacbd\uc808 \uc138\ud3ec(RGC)\uc5d0 \ub300\ud55c \ubcf4\ud638 \ud6a8\uacfc\ub97c \uc785\uc99d\ud588\uc2b5\ub2c8\ub2e4. \uc0c8\ub85c\uc6b4 \uc2e0\uacbd \ubcf4\ud638\uc81c\ub85c\uc11c PQQ\ub294 \ub9dd\ub9c9 \uc2e0\uacbd\uc808 \uc138\ud3ec\uc790\uba78\uc0ac\ub97c \uc5b5\uc81c\ud558\ub294 \ub370 \ud070 \uc7a0\uc7ac\ub825\uc744 \uac00\uc9c0\uace0 \uc788\uc73c\uba70, \uc774\ub294 PQQ\uac00 \uc0c8\ub85c\uc6b4 \uc2dc\uac01 \uc2e0\uacbd \ubcf4\ud638\uc81c\ub85c\uc11c \ub9dd\ub9c9 \uc2e0\uacbd\uc808 \uc138\ud3ec \ud68c\ubcf5\ub825\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \uc7a0\uc7ac\uc801 \ubd80\uc791\uc6a9 \uc704\ud5d8\uc744 \uc904\uc774\ub294 \ub370 \uae30\uc5ec\ud560 \uc218 \uc788\uc74c\uc744 \ub4b7\ubc1b\uce68\ud569\ub2c8\ub2e4. 2023\ub144 12\uc6d4, \ub3d9\uc9c0\ub300\ud559\uad50 \uc758\uacfc\ub300\ud559 \uc0c1\ud558\uc774 \ubd80\uc18d \uc81c10\uc778\ubbfc\ubcd1\uc6d0 \uc5f0\uad6c\ud300\uc740 PQQ \ubcf4\ucda9\uc81c\uac00 \uc7a5\ub0b4 \uc138\uade0\ucd1d\uc744 \uc870\uc808\ud558\uace0, \uc7a5 \uc190\uc0c1\uc744 \uc644\ud654\ud558\uba70, \uac11\uc0c1\uc120 \uae30\ub2a5\uc744 \uac1c\uc120\ud560 \uc218 \uc788\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\ub97c Pol J Microbiol \uc800\ub110\uc5d0 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

(II) \uc751\uc6a9 \ubd84\uc57c \ud655\ub300<\/h3>\n

PQQ\uc5d0 \ub300\ud55c \uc5f0\uad6c\uac00 \uc9c0\uc18d\uc801\uc73c\ub85c \uc2ec\ud654\ub428\uc5d0 \ub530\ub77c \ub2e4\uc591\ud55c \ubd84\uc57c\uc5d0\uc11c PQQ\uc758 \uc751\uc6a9 \ubd84\uc57c\uac00 \uc810\ucc28 \ud655\ub300\ub418\uc5b4 \uad11\ubc94\uc704\ud55c \uac1c\ubc1c \uc804\ub9dd\uc744 \ubcf4\uc5ec\uc8fc\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc2dd\ud488 \ubd84\uc57c\uc5d0\uc11c\ub294 2022\ub144\uacfc 2023\ub144\uc5d0 \uad6d\uac00\uc704\uc0dd\uac74\uac15\uc704\uc6d0\ud68c\uac00 \ud654\ud559 \ud569\uc131 \ubc0f \ubc1c\ud6a8\ub97c \ud1b5\ud574 \uc0dd\uc0b0\ub41c PQQ \uc774\ub098\ud2b8\ub968\uc5fc\uc744 \uac01\uac01 \uc0c8\ub85c\uc6b4 \uc2dd\ud488 \uc6d0\ub8cc\ub85c \uc2b9\uc778\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc2dd\ud488\uc5d0\uc11c PQQ \uc0ac\uc6a9\uc5d0 \ub300\ud55c \ud569\ubc95\uc801\uc774\uace0 \uaddc\uc815\uc744 \uc900\uc218\ud558\ub294 \uc99d\uac70\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \ud604\uc7ac PQQ\ub294 \uc74c\ub8cc \ubc0f \uae30\ud0c0 \uc2dd\ud488\uc5d0 \uc0ac\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uace0\ud615 \uc74c\ub8cc\uc758 \uacbd\uc6b0, \uc7ac\uad6c\uc131 \ud6c4 \uc561\uccb4\uc758 \ubb34\uac8c\ub97c \uae30\uc900\uc73c\ub85c \uacc4\uc0b0\ud55c \uc77c\uc77c \uc12d\ucde8\ub7c9\uc740 20mg\uc744 \ucd08\uacfc\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4. \ub2e8, \uc601\uc720\uc544, \uc784\uc0b0\ubd80 \ubc0f \ubaa8\uc720 \uc218\uc720 \uc911\uc778 \uc5ec\uc131\uc5d0\uac8c\ub294 \uc801\ud569\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ub2e4\uc591\ud55c \uac74\uac15 \ud6a8\ub2a5\uc744 \uc9c0\ub2cc \uc131\ubd84\uc73c\ub85c\uc11c PQQ\ub294 \uc2dd\ud488 \uc0b0\uc5c5\uc5d0 \uae30\ub2a5\uc131 \uc2dd\ud488 \uac1c\ubc1c\uc5d0 \uc0c8\ub85c\uc6b4 \uac00\ub2a5\uc131\uc744 \uc81c\uc2dc\ud569\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uc77c\ubd80 \ube0c\ub79c\ub4dc\ub294 \uc5d0\ub108\uc9c0 \uc218\uce58\ub97c \ub192\uc774\uace0 \ud53c\ub85c\ub97c \uc644\ud654\ud558\uba70 \uac74\uac15\ud558\uace0 \ud3b8\ub9ac\ud55c \uc2dd\ud488\uc5d0 \ub300\ud55c \ud604\ub300 \uc18c\ube44\uc790\ub4e4\uc758 \uc218\uc694\ub97c \ucda9\uc871\uc2dc\ud0a8\ub2e4\ub294 PQQ\uac00 \ud568\uc720\ub41c \uc5d0\ub108\uc9c0 \ub4dc\ub9c1\ud06c\ub97c \ucd9c\uc2dc\ud588\uc2b5\ub2c8\ub2e4. \uc55e\uc73c\ub85c \uac74\uac15\uc2dd\ud488\uc5d0 \ub300\ud55c \uc218\uc694\uac00 \uacc4\uc18d \uc99d\uac00\ud568\uc5d0 \ub530\ub77c \uc2dd\ud488 \uc0b0\uc5c5\uc5d0\uc11c PQQ\uc758 \ud65c\uc6a9 \ubc94\uc704\ub294 \ub354\uc6b1 \ud655\ub300\ub420 \uac83\uc73c\ub85c \uc608\uc0c1\ub418\uba70, \uae30\ub2a5\uc131 \uc2a4\ub0b5\uc774\ub098 \uc601\uc591 \ubc14 \ub4f1 \ub354 \ub2e4\uc591\ud55c \uc2dd\ud488 \uce74\ud14c\uace0\ub9ac\ub85c \ud655\uc7a5\ub420 \uac00\ub2a5\uc131\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uac74\uac15 \ubcf4\uc870 \uc2dd\ud488 \ubd84\uc57c\uc5d0\uc11c PQQ\ub294 \uc624\ub7ab\ub3d9\uc548 \uc778\uae30 \uc788\ub294 \uc8fc\uc694 \uc131\ubd84\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \uac15\ub825\ud55c \ud56d\uc0b0\ud654, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc99d\uc9c4, \uba74\uc5ed \uac15\ud654 \ud6a8\uacfc \ub355\ubd84\uc5d0 PQQ\ub294 \ub2e4\uc591\ud55c \uac74\uac15 \ubcf4\uc870 \uc2dd\ud488\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\uace0 \uc788\uc73c\uba70, \ud2b9\ud788 \ub178\ud654 \ubc29\uc9c0, \ub1cc \uae30\ub2a5, \uba74\uc5ed \uac15\ud654\ub97c \uc704\ud55c \uac74\uac15 \ubcf4\uc870 \uc2dd\ud488\uc5d0 \ub9ce\uc774 \uc0ac\uc6a9\ub429\ub2c8\ub2e4. \ub9ce\uc740 \uc18c\ube44\uc790\ub4e4\uc774 \uc2e0\uccb4 \uae30\ub2a5 \ud5a5\uc0c1 \ubc0f \ub178\ud654 \uc9c0\uc5f0\uc744 \uc704\ud574 PQQ \ubcf4\ucda9\uc81c\ub97c \uc77c\uc0c1\uc801\uc778 \uac74\uac15 \uad00\ub9ac \uc635\uc158\uc73c\ub85c \ud65c\uc6a9\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc77c\ubd80 \uc720\uba85 \uac74\uac15 \ubcf4\uc870 \uc2dd\ud488 \ube0c\ub79c\ub4dc\uc5d0\uc11c \ucd9c\uc2dc\ud55c PQQ \uc81c\ud488\uc740 \ub192\uc740 \ub9e4\ucd9c\uc744 \uae30\ub85d\ud558\uba70 \uc18c\ube44\uc790\ub4e4\uc758 \uc778\uc9c0\ub3c4\ub97c \ub192\uc774\uace0 \uc788\uc2b5\ub2c8\uc804 \uc138\uacc4\uc801\uc73c\ub85c \uace0\ub839 \uc778\uad6c\uac00 \uc99d\uac00\ud558\uace0 \uac74\uac15\uacfc \ub178\ud654 \ubc29\uc9c0\uc5d0 \ub300\ud55c \uad00\uc2ec\uc774 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c PQQ \uac74\uac15 \ubcf4\uc870 \uc2dd\ud488 \uc2dc\uc7a5\uc740 \uc9c0\uc18d\uc801\uc73c\ub85c \uc131\uc7a5\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4. \uc55e\uc73c\ub85c \uac74\uac15 \ubcf4\uc870 \uc2dd\ud488 \ud68c\uc0ac\ub4e4\uc740 PQQ \uc81c\ud488\uc5d0 \ub300\ud55c R&D \ubc0f \ud601\uc2e0 \ub178\ub825\uc744 \ub354\uc6b1 \uac15\ud654\ud558\uc5ec \ub2e4\uc591\ud55c \uc18c\ube44\uc790\uce35\uc758 \ub2c8\uc988\ub97c \ucda9\uc871\ud558\ub294 \ub354\uc6b1 \uc9d1\uc911\uc801\uc774\uace0 \ud6a8\uacfc\uc801\uc778 \uc81c\ud488\uc744 \uac1c\ubc1c\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.<\/p>\n

PQQ\ub294 \ud654\uc7a5\ud488 \ubd84\uc57c\uc5d0\uc11c\ub3c4 \ub3c5\ubcf4\uc801\uc778 \uc7a0\uc7ac\ub825\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \ud56d\uc0b0\ud654 \ubc0f \ud56d\uc5fc\uc99d \ud6a8\uacfc\ub97c \ud1b5\ud574 \ud53c\ubd80 \ub178\ud654 \ubc29\uc9c0, \ud53c\ubd80 \uc5fc\uc99d \uac1c\uc120, \ud53c\ubd80 \uc790\uac00 \ud68c\ubcf5 \ub2a5\ub825 \ud5a5\uc0c1\uc5d0 \ud6a8\uacfc\uc801\uc785\ub2c8\ub2e4. \ud6c4\ub09c\uc218\uc774\uc591\uc0dd\ubb3c\uae30\uc220(\uc8fc)\uc758 PQQ \uc774\ub098\ud2b8\ub968\uc5fc\uc740 \uad6d\uac00\uc57d\ud488\uac10\ub3c5\uad00\ub9ac\ucd1d\uad6d(NMPA)\uc758 \ud654\uc7a5\ud488 \uc2e0\uc6d0\ub8cc\ub85c \ub4f1\ub85d \uc2b9\uc778\uc744 \ubc1b\uc558\uc73c\uba70 \ud604\uc7ac \ubaa8\ub2c8\ud130\ub9c1 \uc911\uc785\ub2c8\ub2e4. \uc77c\ubd80 \ud654\uc7a5\ud488 \ube0c\ub79c\ub4dc\ub294 PQQ\ub97c \uc2a4\ud0a8\ucf00\uc5b4 \uc81c\ud488\uc5d0 \ud1b5\ud569\ud558\uc5ec \ud56d\uc0b0\ud654, \ud53c\ubd80 \ud0c4\ub825 \uac15\ud654, \uc8fc\ub984 \uac1c\uc120 \ud6a8\uacfc\ub97c \uac00\uc9c4 \uc81c\ud488\uc744 \ucd9c\uc2dc\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc81c\ud488\ub4e4\uc740 \ud53c\ubd80 \uc9c8\uc744 \uac1c\uc120\ud558\uc5ec \ud53c\ubd80\ub97c \ub354\uc6b1 \ub9e4\ub044\ub7fd\uace0 \ud0c4\ub825 \uc788\uac8c \uac00\uafd4\uc900\ub2e4\uace0 \uc8fc\uc7a5\ud569\ub2c8\ub2e4. \uae30\ub2a5\uc131 \uc2a4\ud0a8\ucf00\uc5b4 \uc81c\ud488\uc5d0 \ub300\ud55c \uc18c\ube44\uc790 \uc218\uc694\uac00 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c PQQ\ub294 \ud654\uc7a5\ud488 \ubd84\uc57c\uc5d0\uc11c \ud070 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc8fc\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc55e\uc73c\ub85c \ud654\uc7a5\ud488 \uc5c5\uacc4\ub294 PQQ\ub97c \uc911\uc2ec\uc73c\ub85c \ub354 \ub9ce\uc740 \uc5f0\uad6c\uc640 \ud601\uc2e0\uc744 \ucd94\uc9c4\ud558\uc5ec \uc18c\ube44\uc790\ub4e4\uc758 \uc544\ub984\ub2e4\uc6c0\uacfc \uac74\uac15 \ucd94\uad6c\ub97c \ucda9\uc871\ud558\ub294 \uace0\ud488\uc9c8, \uace0\uc131\ub2a5 PQQ \ud654\uc7a5\ud488\uc744 \uac1c\ubc1c\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4.<\/p>\n

\uc758\ub8cc \ubd84\uc57c\uc5d0\uc11c PQQ\ub294 \uc544\uc9c1 \uc784\uc0c1 \uce58\ub8cc\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\uc9c0\ub294 \uc54a\uc558\uc9c0\ub9cc, \uc218\ub9ce\uc740 \uc5f0\uad6c \uacb0\uacfc\ub97c \ud1b5\ud574 PQQ \uac1c\ubc1c\uc758 \ud0c4\ud0c4\ud55c \ud1a0\ub300\ub97c \ub9c8\ub828\ud588\uc2b5\ub2c8\ub2e4. \uc2ec\ud608\uad00, \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658, \ub300\uc0ac \uc9c8\ud658\uc5d0 \ub300\ud55c PQQ\uc758 \uc7a0\uc7ac\uc801 \uce58\ub8cc \ud6a8\uacfc\ub294 \uc218\ub9ce\uc740 \uc81c\uc57d \ud68c\uc0ac\uc640 \uc5f0\uad6c \uae30\uad00\uc758 \uad00\uc2ec\uc744 \ub04c\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc77c\ubd80 \uc5f0\uad6c\uc5d0\uc11c\ub294 \ud3d0\ub3d9\ub9e5 \uace0\ud608\uc555\uc774\ub098 \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658\uacfc \uac19\uc740 \ud2b9\uc815 \uc9c8\ud658\uc758 \ubcf4\uc870 \uc694\ubc95 \ub610\ub294 \ub2e8\ub3c5 \uc694\ubc95\uc73c\ub85c\uc11c PQQ\uc758 \uc7a0\uc7ac\ub825\uc744 \ud0d0\uad6c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc55e\uc73c\ub85c PQQ\uac00 \uc758\ub8cc \ubd84\uc57c\uc5d0\uc11c \ub354 \ud070 \ub3cc\ud30c\uad6c\ub97c \ucc3e\uace0 \uc784\uc0c1 \uce58\ub8cc\uc5d0 \uc131\uacf5\uc801\uc73c\ub85c \uc801\uc6a9\ub420 \uc218 \uc788\ub2e4\uba74, \ub9ce\uc740 \ud658\uc790\ub4e4\uc5d0\uac8c \uc0c8\ub85c\uc6b4 \uce58\ub8cc \uc635\uc158\uacfc \ud76c\ub9dd\uc744 \uac00\uc838\ub2e4\uc904 \uac83\uc774\uba70, \uadf8 \uc2dc\uc7a5 \uac00\uce58\ub294 \ud5e4\uc544\ub9b4 \uc218 \uc5c6\uc744 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

\ud569\ub9ac\uc801\uc778 PQQ \ubcf4\ucda9\uc81c<\/h2>\n

\"\"<\/p>\n

(I) \ubcf4\ucda9\uc81c\uc758 \ud544\uc694\uc131
\nPQQ\uc758 \ud544\uc694\uc131\uc740 \uc778\uad6c \uc9d1\ub2e8\ub9c8\ub2e4 \uc0c1\ub2f9\ud788 \ub2e4\ub974\uae30 \ub54c\ubb38\uc5d0 PQQ \ubcf4\ucda9\uc740 \ub9e4\uc6b0 \uc2e4\uc6a9\uc801\uc73c\ub85c \uc911\uc694\ud569\ub2c8\ub2e4. \uc911\ub144 \ubc0f \ub178\ub144\uce35\uc758 \uacbd\uc6b0, \ub098\uc774\uac00 \ub4e4\uba74\uc11c \uc7a5\uae30 \uae30\ub2a5\uc774 \uc810\ucc28 \uac10\uc18c\ud558\uace0 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5\ub3c4 \uc800\ud558\ub418\uba70, \uc790\uc720 \ub77c\ub514\uce7c \uc0dd\uc131\uc774 \uc99d\uac00\ud558\uace0 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uac00 \uc2ec\ud654\ub418\uc5b4 \uc2e0\uccb4\uac00 \ub2e4\uc591\ud55c \uc9c8\ubcd1\uc5d0 \ub354 \ucde8\uc57d\ud574\uc9d1\ub2c8\ub2e4. \ub530\ub77c\uc11c PQQ \ubcf4\ucda9\uc740 \ud2b9\ud788 \uc911\uc694\ud569\ub2c8\ub2e4. PQQ\uc758 \uac15\ub825\ud55c \ud56d\uc0b0\ud654 \ub2a5\ub825\uc740 \uccb4\ub0b4 \uacfc\ub3c4\ud55c \uc790\uc720 \ub77c\ub514\uce7c\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uc81c\uac70\ud558\uc5ec \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub85c \uc778\ud55c \uc138\ud3ec \uc190\uc0c1\uc744 \uc904\uc774\uace0 \ub178\ud654 \uacfc\uc815\uc744 \ub2a6\ucda5\ub2c8\ub2e4. \ub610\ud55c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc758 \uc0dd\ud569\uc131\uacfc \uae30\ub2a5\uc744 \ucd09\uc9c4\ud558\uc5ec \uc138\ud3ec\uc5d0 \ub354 \ub9ce\uc740 \uc5d0\ub108\uc9c0\ub97c \uc81c\uacf5\ud558\uace0 \ub2e4\uc591\ud55c \uc7a5\uae30\uc758 \uc815\uc0c1\uc801\uc778 \uae30\ub2a5\uc744 \uc720\uc9c0\ud569\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc911\ub144 \ubc0f \ub178\ub144\uce35\uc5d0\uc11c \uc801\ub2f9\ud55c \uc591\uc758 PQQ \ubcf4\ucda9\uc740 \ud53c\ub85c\ub97c \ud604\uc800\ud788 \uac10\uc18c\uc2dc\ud0a4\uace0 \uba74\uc5ed\ub825\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uba70 \uc218\uba74\uc758 \uc9c8\uc744 \uac1c\uc120\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n

PQQ \ubcf4\ucda9\uc740 \uc7a5\uae30\uac04 \uace0\uac15\ub3c4 \ub178\ub3d9\uacfc \ub192\uc740 \uc815\uc2e0\uc801 \uc2a4\ud2b8\ub808\uc2a4\ub97c \uacaa\ub294 \uc0ac\ub78c\ub4e4\uc5d0\uac8c\ub3c4 \ud544\uc218\uc801\uc785\ub2c8\ub2e4. \ub192\uc740 \uc2a4\ud2b8\ub808\uc2a4 \uc0c1\ud669\uc5d0\uc11c\ub294 \uc2e0\uccb4\uac00 \ub2e4\ub7c9\uc758 \uc2a4\ud2b8\ub808\uc2a4 \ud638\ub974\ubaac\uc744 \uc0dd\uc131\ud558\ub294\ub370, \uc774\ub294 \uc2e0\uc9c4\ub300\uc0ac\ub97c \ucd09\uc9c4\ud558\uace0, \ud65c\uc131\uc0b0\uc18c \uc0dd\uc131\uc744 \uc99d\uac00\uc2dc\ud0a4\uba70, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. PQQ\ub294 \uc2e0\uccb4\uc758 \uc2a4\ud2b8\ub808\uc2a4 \ubc18\uc751\uc744 \uc870\uc808\ud558\uace0, \ud65c\uc131\uc0b0\uc18c \uc0dd\uc131\uc744 \uc904\uc774\uba70, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc190\uc0c1\uc744 \ubc29\uc9c0\ud569\ub2c8\ub2e4. \ub610\ud55c \uc2e0\uacbd \uc131\uc7a5 \uc778\uc790\uc758 \ud569\uc131\uacfc \ubd84\ube44\ub97c \ucd09\uc9c4\ud558\uc5ec \uc2a4\ud2b8\ub808\uc2a4\ub97c \uc644\ud654\ud558\uace0 \ubd88\uc548, \uc6b0\uc6b8\uc99d, \uae30\ud0c0 \ubd80\uc815\uc801\uc778 \uac10\uc815\uc744 \uac1c\uc120\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c \uc778\uc9c0 \uae30\ub2a5\uacfc \uc5c5\ubb34 \ud6a8\uc728\uc131\uc744 \ud5a5\uc0c1\uc2dc\ucf1c \uac74\uac15\ud55c \uc2e0\uccb4\uc801, \uc815\uc2e0\uc801 \uc0c1\ud0dc\ub97c \uc720\uc9c0\ud558\uace0 \uc9c1\uc7a5\uacfc \uc0b6\uc758 \uc5b4\ub824\uc6c0\uc5d0 \ub354 \uc798 \ub300\ucc98\ud558\ub3c4\ub85d \ub3d5\uc2b5\ub2c8\ub2e4.<\/p>\n

\uac10\uae30\uc5d0 \uc790\uc8fc \uac78\ub9ac\uac70\ub098 \uac10\uc5fc\uc5d0 \ucde8\uc57d\ud55c \ub4f1 \uba74\uc5ed \uccb4\uacc4\uac00 \uc57d\ud654\ub41c \uc0ac\ub78c\ub4e4\uc5d0\uac8c PQQ \ubcf4\ucda9\uc81c\ub294 \uc5ec\ub7ec \uce21\uba74\uc5d0\uc11c \uba74\uc5ed\ub825\uc744 \uac15\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uba74\uc5ed \uc138\ud3ec\uc758 \uc99d\uc2dd\uacfc \ubd84\ud654\ub97c \ucd09\uc9c4\ud558\uace0, \uba74\uc5ed \uc138\ud3ec \ud65c\ub3d9\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uba70, \uba74\uc5ed \uc138\ud3ec \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc870\uc808\ud558\uc5ec \uba74\uc5ed \uccb4\uacc4\uac00 \ubcd1\uc6d0\uccb4\ub97c \ub354\uc6b1 \ud6a8\uacfc\uc801\uc73c\ub85c \uc2dd\ubcc4\ud558\uace0 \uc81c\uac70\ud560 \uc218 \uc788\ub3c4\ub85d \ud569\ub2c8\ub2e4. \uc774\ub97c \ud1b5\ud574 \uac10\uc5fc\uc131 \uc9c8\ud658\uc758 \uc704\ud5d8\uc744 \uc904\uc774\uace0, \uc2e0\uccb4\uc758 \uc800\ud56d\ub825\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uba70, \uc9c8\ubcd1\uc5d0 \ub300\ud55c \uc800\ud56d\ub825\uc744 \uac15\ud654\ud569\ub2c8\ub2e4.<\/p>\n

(II) \uacfc\ud559\uc801 \ubcf4\ucda9\uc81c \uad8c\uc7a5 \uc0ac\ud56d
\nPQQ \ubcf4\ucda9\uc81c\ub97c \uc120\ud0dd\ud560 \ub54c \uace0\ub824\ud574\uc57c \ud560 \uba87 \uac00\uc9c0 \ud575\uc2ec \uc0ac\ud56d\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uccab\uc9f8, \uc81c\uc870\uc5c5\uccb4\uc758 \ud3c9\ud310\uc774 \uc911\uc694\ud569\ub2c8\ub2e4. \uc88b\uc740 \ud3c9\ud310, \uc88b\uc740 \ud3c9\ud310, \uadf8\ub9ac\uace0 \uc790\uaca9\uc744 \uac16\ucd98 \uc81c\uc870\uc5c5\uccb4\ub97c \uc120\ud0dd\ud558\uba74 \ucd5c\uace0\uc758 \ud488\uc9c8\uacfc \uc548\uc804\uc131\uc744 \ubcf4\uc7a5\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc81c\uc870\uc5c5\uccb4\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \uc5c4\uaca9\ud55c \uc0dd\uc0b0 \uae30\uc900\uacfc \ud488\uc9c8 \uad00\ub9ac \uc2dc\uc2a4\ud15c\uc744 \uac16\ucd94\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc6d0\uc790\uc7ac \uc870\ub2ec\ubd80\ud130 \uc0dd\uc0b0 \ubc0f \uac00\uacf5, \uc644\uc81c\ud488 \ud14c\uc2a4\ud2b8\uc5d0 \uc774\ub974\uae30\uae4c\uc9c0 \ubaa8\ub4e0 \ub2e8\uacc4\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \ubaa8\ub2c8\ud130\ub9c1\ud558\uc5ec \uc81c\ud488\uc774 \uad00\ub828 \ud488\uc9c8 \ubc0f \uc548\uc804 \uae30\uc900\uc744 \ucda9\uc871\ud558\ub294\uc9c0 \ud655\uc778\ud569\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uc77c\ubd80 \uc720\uba85 PQQ \ubcf4\ucda9\uc81c \ube0c\ub79c\ub4dc\ub294 \uc624\ub79c \ud310\ub9e4 \uc5ed\uc0ac\ub97c \uac00\uc9c0\uace0 \uc788\uc73c\uba70 \uc18c\ube44\uc790\ub4e4\uc5d0\uac8c \uad11\ubc94\uc704\ud55c \ud14c\uc2a4\ud2b8\ub97c \uac70\uccd0 \ud488\uc9c8\uacfc \ud6a8\ub2a5\uc5d0 \ub300\ud55c \ud3ed\ub113\uc740 \uc778\uc815\uc744 \ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub458\uc9f8, \uc81c\ud488\uc758 \uc131\ubd84\uacfc \uc21c\ub3c4\uac00 \uc911\uc694\ud569\ub2c8\ub2e4. \uace0\ud488\uc9c8 PQQ \ubcf4\ucda9\uc81c\ub294 \uc21c\ub3c4\uac00 \ub192\uace0 \uc720\ud574\ud55c \ucca8\uac00\ubb3c\uacfc \ubd88\uc21c\ubb3c\uc774 \uc5c6\uc5b4\uc57c \ud569\ub2c8\ub2e4. \uace0\uc21c\ub3c4 PQQ \ubcf4\ucda9\uc81c\ub294 \ucda9\ubd84\ud55c \uc591\uc758 \ud65c\uc131 \uc131\ubd84\uc744 \ud568\uc720\ud558\uc5ec \ucd5c\uc801\uc758 \ud6a8\ub2a5\uc744 \ubcf4\uc7a5\ud569\ub2c8\ub2e4. \uc81c\ud488 \ub77c\ubca8\uc744 \uac80\ud1a0\ud560 \ub54c PQQ \ud568\ub7c9\uacfc \uc21c\ub3c4\ub97c \uc2e0\uc911\ud558\uac8c \ud655\uc778\ud558\uc2ed\uc2dc\uc624. \uc77c\ubc18\uc801\uc73c\ub85c \uc21c\ub3c4\uac00 \ub192\uc744\uc218\ub85d \uc81c\ud488\uc758 \ud488\uc9c8\uc774 \uc88b\uc2b5\ub2c8\ub2e4. \ub610\ud55c, \uacfc\ub3c4\ud55c \uc591\uc758 \uc778\uacf5 \uc0c9\uc18c, \ud5a5\ub8cc, \ubc29\ubd80\uc81c \ubc0f \uae30\ud0c0 \ucca8\uac00\ubb3c\uc774 \ud568\uc720\ub41c \uc81c\ud488\uc740 \ud53c\ud558\uc2ed\uc2dc\uc624. \uc774\ub7ec\ud55c \uc81c\ud488\uc740 \uc7a0\uc7ac\uc801\uc73c\ub85c \uac74\uac15\uc5d0 \uc545\uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

PQQ \ubcf4\ucda9\uc81c\uc758 \ubcf5\uc6a9\ub7c9 \ub610\ud55c \uc2e0\uc911\ud558\uac8c \uc870\uc808\ud574\uc57c \ud569\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c \uc131\uc778\uc758 PQQ \uad8c\uc7a5 \uc77c\uc77c \uc12d\ucde8\ub7c9\uc740 10~20mg\uc774\uc9c0\ub9cc, \uac1c\uc778\uc758 \uc2e0\uccb4 \uc0c1\ud0dc, \uc5f0\ub839 \ubc0f \uac74\uac15 \uc0c1\ud0dc\uc5d0 \ub530\ub77c \uad6c\uccb4\uc801\uc778 \ubcf5\uc6a9\ub7c9\uc744 \uc870\uc808\ud574\uc57c \ud569\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uba74\uc5ed\ub825 \uac15\ud654\uac00 \ud544\uc694\ud55c \uccb4\uc9c8\uc740 \ub354 \ub192\uc740 \ubcf5\uc6a9\ub7c9\uc774 \ud544\uc694\ud560 \uc218 \uc788\uc73c\uba70, \uac74\uac15 \uc0c1\ud0dc\uac00 \uc591\ud638\ud55c \uc0ac\ub78c\uc740 \uc77c\uc0c1\uc801\uc778 \uac74\uac15\uc744 \uc704\ud574 \ub354 \ub0ae\uc740 \ubcf5\uc6a9\ub7c9\uc744 \uc120\ud0dd\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. PQQ \ubcf4\ucda9\uc81c\ub97c \uc0ac\uc6a9\ud558\uae30 \uc804\uc5d0 \uc758\uc0ac \ub610\ub294 \uc601\uc591\uc0ac\uc640 \uc0c1\ub2f4\ud558\ub294 \uac83\uc774 \uac00\uc7a5 \uc88b\uc2b5\ub2c8\ub2e4. \uc758\uc0ac \ub610\ub294 \uc601\uc591\uc0ac\ub294 \uac1c\uc778\uc758 \uc0c1\ud669\uc5d0 \ub9de\ub294 \ubcf5\uc6a9\ub7c9 \uad8c\uc7a5 \uc0ac\ud56d\uc744 \uc81c\uacf5\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub610\ud55c, PQQ\uc640 \uc57d\ubb3c\uc758 \uc0c1\ud638\uc791\uc6a9\uc5d0 \uc720\uc758\ud558\uc2ed\uc2dc\uc624. PQQ\uc640 \uc57d\ubb3c \uc0c1\ud638\uc791\uc6a9\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub294 \ube44\uad50\uc801 \uc81c\ud55c\uc801\uc774\uc9c0\ub9cc, \uc77c\ubd80 \uc5f0\uad6c\uc5d0\uc11c\ub294 PQQ\uac00 \ud2b9\uc815 \uc57d\ubb3c\uacfc \uc0c1\ud638\uc791\uc6a9\ud558\uc5ec \uc57d\ubb3c\uc758 \ud6a8\uacfc\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\uac70\ub098 \ubd80\uc791\uc6a9 \uc704\ud5d8\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\ub2e4\uace0 \uc2dc\uc0ac\ud569\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, PQQ\ub294 \ud56d\uc751\uace0\uc81c\uc758 \ud6a8\uacfc\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\uace0 \ucd9c\ud608 \uc704\ud5d8\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc815\uc2e0\uacfc \uc57d\ubb3c\uacfc \ubcd1\uc6a9 \ud22c\uc5ec \uc2dc \ud604\uae30\uc99d, \uc878\uc74c, \uae30\ud0c0 \ubd88\ud3b8\ud568\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \ub2e4\ub978 \uc57d\ubb3c\uc744 \ubcf5\uc6a9 \uc911\uc778 \ubd84\uc740 PQQ \ubcf4\ucda9\uc81c \ubcf5\uc6a9 \uc804\uc5d0 \uc758\uc0ac\uc640 \uc0c1\ub2f4\ud558\uc2ed\uc2dc\uc624. \uc758\uc0ac\ub294 \uc57d\ubb3c \uc885\ub958\uc640 \uac1c\uc778 \uac74\uac15 \uc0c1\ud0dc\uc5d0 \ub530\ub77c PQQ \ubcf4\ucda9\uc81c\uc758 \uc801\ud569\uc131\uc744 \ud3c9\uac00\ud558\uace0 \uc801\uc808\ud55c \uad8c\uc7a5 \uc0ac\ud56d\uc744 \uc81c\uacf5\ud560 \uac83\uc785\ub2c8\ub2e4. PQQ \ubcf5\uc6a9 \uc911 \ubd88\ud3b8\ud568\uc774 \ubc1c\uc0dd\ud558\uba74 \uc989\uc2dc \ubcf5\uc6a9\uc744 \uc911\ub2e8\ud558\uace0\uc758\uc0ac\uc758 \uc9c4\ub8cc\ub97c \ubc1b<\/p>\n

PQQ \ubcf4\ucda9\uc81c\ub294 \ubaa8\ub4e0 \uc0ac\ub78c\uc5d0\uac8c \uc801\ud569\ud55c \uac83\uc740 \uc544\ub2d9\ub2c8\ub2e4. \uc5b4\ub9b0\uc774\ub294 \uc131\uc7a5\uacfc \ubc1c\ub2ec\uc5d0 \uc911\uc694\ud55c \uc2dc\uae30\ub97c \uacaa\uace0 \uc788\uc73c\uba70, \uc2e0\uccb4\ub294 \uc131\uc778\uacfc\ub294 \ub2e4\ub978 \ubc29\uc2dd\uc73c\ub85c \ub2e4\uc591\ud55c \ubb3c\uc9c8\uc744 \ub300\uc0ac\ud558\uace0 \uc801\uc751\ud569\ub2c8\ub2e4. \ud604\uc7ac PQQ\uac00 \uc5b4\ub9b0\uc774\uc758 \uc131\uc7a5\uacfc \ubc1c\ub2ec\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub294 \ubd80\uc871\ud558\ubbc0\ub85c \uc5b4\ub9b0\uc774\uc5d0\uac8c PQQ\ub97c \uc77c\uc0c1\uc801\uc73c\ub85c \uc12d\ucde8\ud558\ub294 \uac83\uc740 \uad8c\uc7a5\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc784\uc0b0\ubd80\uc640 \uc218\uc720\ubd80\ub294 \ud2b9\ubcc4\ud55c \uc2e0\uccb4\uc801 \uc870\uac74\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub4e4\uc758 \uc2dd\ub2e8\uacfc \uc601\uc591 \uc12d\ucde8\ub294 \ubcf8\uc778\uc758 \uac74\uac15\ubfd0\ub9cc \uc544\ub2c8\ub77c \ud0dc\uc544 \ub610\ub294 \uc601\uc544\uc758 \uc131\uc7a5\uacfc \ubc1c\ub2ec\uc5d0\ub3c4 \uc9c1\uc811\uc801\uc778 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uc784\uc0b0\ubd80\uc640 \uc218\uc720\ubd80\uc5d0 \ub300\ud55c PQQ\uc758 \uc548\uc804\uc131\uc744 \uc785\uc99d\ud558\ub294 \ucda9\ubd84\ud55c \uc5f0\uad6c \uc790\ub8cc\uac00 \uc5c6\uc73c\ubbc0\ub85c, \uc774 \ub450 \uadf8\ub8f9\uc740 \uc7a0\uc7ac\uc801 \uc704\ud5d8\uc744 \ud53c\ud558\uae30 \uc704\ud574 PQQ \ubcf4\ucda9\uc81c\ub97c \uc2e0\uc911\ud558\uac8c \uc0ac\uc6a9\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

 <\/p>\n

PQQ\ub97c \ubc1b\uc544\ub4e4\uc774\uace0 \uac74\uac15\ud55c \ubbf8\ub798\ub97c \ub9de\uc774\ud558\uc138\uc694<\/h2>\n

\uc790\uc5f0\uc5d0\uc11c \ub110\ub9ac \ubc1c\uacac\ub418\uc9c0\ub9cc \uc885\uc885 \uac04\uacfc\ub418\ub294 \ubb3c\uc9c8\uc778 PQQ\ub294 \ud56d\uc0b0\ud654, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ubcf4\ud638, \ub300\uc0ac \uc870\uc808, \uba74\uc5ed \uc99d\uac15 \ub4f1 \ub3c5\ud2b9\ud55c \ud654\ud559 \uad6c\uc870\ub97c \ud1b5\ud574 \uc778\uac04 \uac74\uac15\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. PQQ\ub294 \uac74\uac15 \uc720\uc9c0\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc138\ud3ec \uc5d0\ub108\uc9c0 \ub300\uc0ac\ubd80\ud130 \uac70\uc2dc\uc0dd\ub9ac\ud559\uc801 \uc870\uc808\uc5d0 \uc774\ub974\uae30\uae4c\uc9c0 PQQ\ub294 \ud0c1\uc6d4\ud55c \uac00\uce58\ub97c \uc785\uc99d\ud558\uba70 \ud604\ub300 \uc0ac\ud68c\uc758 \ub2e4\uc591\ud55c \uac74\uac15 \ubb38\uc81c\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \ud574\uacb0\ucc45\uc744 \uc81c\uc2dc\ud569\ub2c8\ub2e4.<\/p>\n

\uacfc\ud559 \uc5f0\uad6c\uc758 \uc9c0\uc18d\uc801\uc778 \ubc1c\uc804\uacfc \ub354\ubd88\uc5b4 \ub178\ud654 \uc9c0\uc5f0, \uc778\uc9c0 \uae30\ub2a5 \ud5a5\uc0c1, \uc9c8\ubcd1 \uc608\ubc29 \ubd84\uc57c\uc5d0\uc11c PQQ\uc758 \ud65c\uc6a9\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \ub3cc\ud30c\uad6c\uac00 \ub9c8\ub828\ub418\uba74\uc11c PQQ\uc758 \uac74\uac15 \uc7a0\uc7ac\ub825\uc5d0 \ub300\ud55c \ub354\uc6b1 \ud3ec\uad04\uc801\uc774\uace0 \uc2ec\uce35\uc801\uc778 \uc774\ud574\uac00 \uac00\ub2a5\ud574\uc84c\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc5f0\uad6c \uacb0\uacfc\ub294 \uc2dd\ud488, \uac74\uac15 \ubcf4\uc870 \uc2dd\ud488, \ud654\uc7a5\ud488, \uc758\uc57d\ud488 \ubd84\uc57c\uc5d0\uc11c PQQ\ub97c \uc801\uc6a9\ud558\ub294 \ub370 \uc788\uc5b4 \ud0c4\ud0c4\ud55c \uc774\ub860\uc801 \ud1a0\ub300\ub97c \uc81c\uacf5\ud560 \ubfd0\ub9cc \uc544\ub2c8\ub77c, \uc0b6\uc758 \uc9c8 \ud5a5\uc0c1\uacfc \uac74\uac15 \uc99d\uc9c4\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \ud76c\ub9dd\uc744 \uc81c\uc2dc\ud569\ub2c8\ub2e4.<\/p>\n

\uc55e\uc73c\ub85c \uac74\uac15\uc5d0 \ub300\ud55c \uc0ac\ub78c\ub4e4\uc758 \uc778\uc2dd\uc774 \ub192\uc544\uc9c0\uace0 PQQ \uc5f0\uad6c \ubc0f \ud65c\uc6a9\uc774 \ud655\ub300\ub428\uc5d0 \ub530\ub77c, PQQ\ub294 \uac74\uac15 \ubd84\uc57c\uc5d0\uc11c \ub354\uc6b1 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \uc218\ud589\ud558\uace0 \uc778\ub958 \uac74\uac15\uc5d0 \ub354\uc6b1 \ud06c\uac8c \uae30\uc5ec\ud560 \uac83\uc73c\ub85c \ubbff\uc2b5\ub2c8\ub2e4. PQQ\ub294 \uc6b0\ub9ac\uc758 \uc77c\uc0c1\uc801\uc778 \uac74\uac15 \uad00\ub9ac\uc5d0 \uc5c6\uc5b4\uc11c\ub294 \uc548 \ub420 \ubd80\ubd84\uc774 \ub418\uc5b4 \ub178\ud654\uc640 \uc9c8\ubcd1\uacfc \uac19\uc740 \uc5b4\ub824\uc6c0\uc5d0 \ub354 \uc798 \ub300\ucc98\ud558\uace0 \ub354\uc6b1 \uac74\uac15\ud558\uace0 \ub9cc\uc871\uc2a4\ub7ec\uc6b4 \uc0b6\uc744 \uc601\uc704\ud558\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc904 \uac83\uc785\ub2c8\ub2e4. \uacfc\ud559\uc758 \ubc1c\uc804 \uc18d\ub3c4\uc5d0 \ubc1c\ub9de\ucdb0, \uac74\uac15\uc758 \ubcf4\ubb3c\uc778 PQQ\ub97c \ud569\ub9ac\uc801\uc73c\ub85c \ud65c\uc6a9\ud558\uc5ec \uc790\uc2e0\uacfc \uac00\uc871\uc758 \uac74\uac15\uc744 \uc9c0\ucf1c\ub098\uac00\ub3c4\ub85d \ud569\uc2dc\ub2e4.<\/p>\n","protected":false},"excerpt":{"rendered":"

\ucd5c\uadfc \uba87 \ub144 \ub3d9\uc548 PQQ(\ud53c\ub864\ub85c\ud034\ub180\ub9b0\ud034\ub17c)\ub77c\ub294 \ubb3c\uc9c8\uc774 \uac74\uac15 \ubd84\uc57c\uc5d0\uc11c \ube60\ub974\uac8c \uc778\uae30\ub97c \uc5bb\uc73c\uba70 \uac74\uac15 \uc804\ubb38\uac00\uc640 \uc5f0\uad6c\uc790\ub4e4\uc758 \uc8fc\ubaa9\uc744 \ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ub9ce\uc740 \uc0ac\ub78c\ub4e4\uc774 PQQ\ub97c \uac74\uac15\uc758 \ube44\ubc00\uc744 \ubc1d\ud600\uc8fc\ub294 “\ub9c8\ubc95\uc758 \uc5f4\uc1e0”\ub85c \uc5ec\uae41\ub2c8\ub2e4. \ub2e4\ub978 \uc218\ub9ce\uc740 \uc601\uc591 \uc131\ubd84\ub4e4 \uc911\uc5d0\uc11c\ub3c4 PQQ\uac00 \ub3cb\ubcf4\uc774\ub294 \uc774\uc720\ub294 \ubb34\uc5c7\uc77c\uae4c\uc694? \ub2e8\uc21c\ud55c \uacfc\ub300\uad11\uace0\uc77c\uae4c\uc694, \uc544\ub2c8\uba74 \uc815\ub9d0 \uae30\uc801\uc801\uc778 \ud6a8\ub2a5\uc744 \uac00\uc9c4 \uac83\uc77c\uae4c\uc694? PQQ\uc758 \uc2e0\ube44\ub97c \ud480\uace0 \uadf8 \ub4a4\uc5d0 \uc228\uaca8\uc9c4 \uacfc\ud559\uc801 \ube44\ubc00\uc744 \uc0b4\ud3b4\ubcf4\uaca0\uc2b5\ub2c8\ub2e4. PQQ\ub780 \ubb34\uc5c7\uc77c\uae4c\uc694? (I) … Continue reading PQQ: \uc0b6\uacfc \uac74\uac15\uc758 \uc554\ud638\ub97c \ud480\uc5b4\uc8fc\ub294 \ub9c8\ubc95\uc758 \ubb3c\uc9c8<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":2772,"parent":0,"menu_order":38,"comment_status":"open","ping_status":"open","template":"","format":"standard","meta":{"footnotes":""},"class_list":["post-2771","blog","type-blog","status-publish","format-standard","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog\/2771","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog"}],"about":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/types\/blog"}],"author":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/comments?post=2771"}],"version-history":[{"count":0,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog\/2771\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/media\/2772"}],"wp:attachment":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/media?parent=2771"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}