{"id":2815,"date":"2025-10-16T02:06:52","date_gmt":"2025-10-16T02:06:52","guid":{"rendered":"https:\/\/www.focusherb.com\/kr\/?post_type=blog&p=2815"},"modified":"2025-10-16T02:06:52","modified_gmt":"2025-10-16T02:06:52","slug":"nmn-%eb%b6%84%ec%9e%90-%eb%a9%94%ec%bb%a4%eb%8b%88%ec%a6%98%eb%b6%80%ed%84%b0-%ed%95%ad%eb%85%b8%ed%99%94-%ec%8b%a4%ec%b2%9c%ea%b9%8c%ec%a7%80-%ea%b3%bc%ed%95%99%ec%a0%81-%eb%b6%84%ec%84%9d","status":"publish","type":"blog","link":"https:\/\/www.focusherb.com\/kr\/blog\/nmn-%eb%b6%84%ec%9e%90-%eb%a9%94%ec%bb%a4%eb%8b%88%ec%a6%98%eb%b6%80%ed%84%b0-%ed%95%ad%eb%85%b8%ed%99%94-%ec%8b%a4%ec%b2%9c%ea%b9%8c%ec%a7%80-%ea%b3%bc%ed%95%99%ec%a0%81-%eb%b6%84%ec%84%9d\/","title":{"rendered":"NMN: \ubd84\uc790 \uba54\ucee4\ub2c8\uc998\ubd80\ud130 \ud56d\ub178\ud654 \uc2e4\ucc9c\uae4c\uc9c0 \uacfc\ud559\uc801 \ubd84\uc11d"},"content":{"rendered":"

NMN \ub610\ub294 \u03b2-\ub2c8\ucf54\ud2f4\uc544\ubbf8\ub4dc \ubaa8\ub178\ub274\ud074\ub808\uc624\ud0c0\uc774\ub4dc\ub294 NAD+\uc758 \uc9c1\uc811\uc801\uc778 \uc804\uad6c\uccb4\uc774\uba70 \uc778\uccb4\uc5d0\uc11c \uc790\uc5f0\uc801\uc73c\ub85c \uc0dd\uc131\ub418\ub294 \uc0dd\ub9ac\ud65c\uc131 \ub274\ud074\ub808\uc624\ud0c0\uc774\ub4dc\uc785\ub2c8\ub2e4. \ubd84\uc790 \uad6c\uc870\ub294 \ub2c8\ucf54\ud2f4\uc544\ubbf8\ub4dc\uae30, \ub9ac\ubcf4\uc2a4\ub2f9, \uadf8\ub9ac\uace0 \uc778\uc0b0\uae30\ub85c \uad6c\uc131\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4. \u03b2-\uc774\uc131\uc9c8\uccb4\ub9cc\uc774 \uc0dd\ubb3c\ud559\uc801 \ud65c\uc131\uc744 \uac16\uc2b5\ub2c8\ub2e4. \ubb3c\uc5d0 \uc798 \ub179\uace0 \uc57d\uc0b0\uc131(pH 3-4)\uc774\ubbc0\ub85c \ud65c\uc131\uc744 \uc720\uc9c0\ud558\ub824\uba74 \ube5b\uacfc \ubb3c\uc744 \ud53c\ud574 \ubcf4\uad00\ud574\uc57c \ud569\ub2c8\ub2e4. NMN\uc740 \uc544\ubcf4\uce74\ub3c4\ub098 \uc5d0\ub2e4\ub9c8\uba54\uc640 \uac19\uc740 \uacfc\uc77c\uacfc \ucc44\uc18c\uc5d0 \ud48d\ubd80\ud558\uac8c \ud568\uc720\ub418\uc5b4 \uc788\uc73c\uba70, \uc778\uccb4\uc5d0\uc11c\ub3c4 \ud569\uc131\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ub178\ud654\uac00 \uc9c4\ud589\ub428\uc5d0 \ub530\ub77c \uc2e0\uccb4\uc758 NMN \ud569\uc131 \ub2a5\ub825\uc774 \uac10\uc18c\ud558\uc5ec NMN \uc218\uce58\uac00 \uac10\uc18c\ud569\ub2c8\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \ub2e4\uc591\ud55c \uc5f0\ub839\ub300\uc758 \uc0ac\ub78c\ub4e4\uc758 NMN \uc218\uce58\ub97c \uc815\ud655\ud558\uac8c \uce21\uc815\ud558\uae30 \uc704\ud574 \ucca8\ub2e8 \uac80\ucd9c \uae30\uc220\uc744 \uc0ac\uc6a9\ud588\uace0, \ub178\ud654\uc640 \uba85\ud655\ud55c \uc74c\uc758 \uc0c1\uad00\uad00\uacc4\ub97c \ubc1c\uacac\ud558\uc5ec NMN \ubcf4\ucda9\uc81c \uc12d\ucde8\uc640 \ud56d\ub178\ud654\uc758 \uad00\uacc4\uc5d0 \ub300\ud55c \ucd94\uac00 \uc5f0\uad6c\uc758 \ud1a0\ub300\ub97c \ub9c8\ub828\ud588\uc2b5\ub2c8\ub2e4.\"\"<\/p>\n

\uc0dd\ubb3c\ud559\uc801 \ub300\uc0ac \uacbd\ub85c \ubd84\uc11d<\/h2>\n

NMN<\/strong><\/a>\uc740 \uc138\ud3ec \ub0b4\uc5d0\uc11c NAD+\ub85c \ube60\ub974\uac8c \uc804\ud658\ub418\uc5b4 300\uac00\uc9c0 \uc774\uc0c1\uc758 \uc0dd\ud654\ud559 \ubc18\uc751\uc5d0 \ucc38\uc5ec\ud558\uba70, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc5d0\ub108\uc9c0 \ub300\uc0ac \ubc0f DNA \ubcf5\uad6c \uacbd\ub85c\uc5d0\uc11c \ud575\uc2ec\uc801\uc778 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc138\ud3ec\uc758 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc5d0\uc11c NAD+\ub294 \ud575\uc2ec \uc870\ud6a8\uc18c \uc5ed\ud560\uc744 \ud558\uba70, \ud2b8\ub9ac\uce74\ub974\ubcf5\uc2e4\uc0b0 \ud68c\ub85c \ubc0f \uc0b0\ud654\uc801 \uc778\uc0b0\ud654\uc640 \uac19\uc740 \uc911\uc694\ud55c \uc5d0\ub108\uc9c0 \ub300\uc0ac \uacfc\uc815\uc5d0 \ucc38\uc5ec\ud558\uc5ec \uc138\ud3ec \uc0dd\uba85\uc5d0 \uc9c0\uc18d\uc801\uc778 \uc5d0\ub108\uc9c0\ub97c \uacf5\uae09\ud569\ub2c8\ub2e4. DNA \ubcf5\uad6c\uc640 \uad00\ub828\ud558\uc5ec, \uc138\ud3ec\uac00 \uc790\uc678\uc120, \ud654\ud559 \ubb3c\uc9c8 \ub610\ub294 \uae30\ud0c0 \uc694\uc778\uc5d0 \uc758\ud574 \uc190\uc0c1\ub418\uba74 NAD+ \uc758\uc874\uc131 \ubcf5\uad6c \ud6a8\uc18c\uac00 \ud65c\uc131\ud654\ub418\uc5b4 \uc190\uc0c1\ub41c DNA\ub97c \ubcf5\uad6c\ud558\uace0 \uc720\uc804\uc801 \uc548\uc815\uc131\uc744 \uc720\uc9c0\ud569\ub2c8\ub2e4.<\/p>\n

\ub178\ud654\uac00 \uc9c4\ud589\ub428\uc5d0 \ub530\ub77c NAD+ \uc218\uce58\ub294 20\ub144\ub9c8\ub2e4 \uc57d 50%\uc529 \uac10\uc18c\ud558\uc5ec \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc800\ud558\uc640 DNA \uc190\uc0c1 \ucd95\uc801\uc73c\ub85c \uc774\uc5b4\uc838 \ub178\ud654 \ubc0f \uad00\ub828 \uc9c8\ubcd1\uc758 \uc8fc\uc694 \uc6d0\uc778\uc774 \ub429\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud604\uc0c1\uc740 \uc218\ub9ce\uc740 \ub3d9\ubb3c \uc2e4\ud5d8\uacfc \uc784\uc0c1 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc785\uc99d\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \ub178\ub839 \uc950\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \uc5f0\uad6c\uc5d0\uc11c\ub294 NAD+ \uc218\uce58\uac00 \uc80a\uc740 \uc950\ubcf4\ub2e4 \ud604\uc800\ud788 \ub0ae\uc544 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc5d0\ub108\uc9c0 \uc0dd\uc0b0 \ud6a8\uc728\uc774 \ud06c\uac8c \uac10\uc18c\ud558\uace0 DNA \uc190\uc0c1 \ubd80\uc704\uac00 \ud06c\uac8c \uc99d\uac00\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ud770\uba38\ub9ac \ubc0f \uc6b4\ub3d9 \uae30\ub2a5 \uc800\ud558\uc640 \uac19\uc740 \ub178\ud654 \uad00\ub828 \uc99d\uc0c1\uc774 \ub098\ud0c0\ub098\ub294 \uc6d0\uc778\uc785\ub2c8\ub2e4.<\/p>\n

NMN\uc758 \ud575\uc2ec \ud6a8\ub2a5: \uacfc\ud559\uc801 \uac80\uc99d\uc744 \uae30\ubc18\uc73c\ub85c \ud55c \ub2e4\ucc28\uc6d0\uc801 \uac74\uac15 \ud6a8\ub2a5<\/h2>\n

\"\"<\/p>\n

(I) \ub178\ud654 \ubc29\uc9c0 \ubc0f \uc138\ud3ec \uc7ac\uc0dd<\/h3>\n

NMN\uc758 \ud575\uc2ec \ud6a8\ub2a5\uc740 \uc138\ud3ec \uc218\uc900\uc5d0\uc11c \ub178\ud654\ub97c \uc870\uc808\ud558\ub294 \ub370 \uc911\uc810\uc744 \ub450\uace0 \uc788\uc73c\uba70, \uadf8 \ud575\uc2ec\uc740 \uc7a5\uc218 \ub2e8\ubc31\uc9c8\uc778 \uc2dc\ub974\ud22c\uc778 \uacc4\uc5f4\uc758 \ud65c\uc131\ud654\uc785\ub2c8\ub2e4. \uc774 \ub2e8\ubc31\uc9c8 \uacc4\uc5f4\uc740 \uc138\ud3ec \ub178\ud654 \uacfc\uc815\uc744 \uc870\uc808\ud558\ub294 \ub370 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\uba70, \ub2e4\uc591\ud55c \uba54\ucee4\ub2c8\uc998\uc744 \ud1b5\ud574 \uc138\ud3ec \ub178\ud654\ub97c \uc9c0\uc5f0\uc2dc\ud0b5\ub2c8\ub2e4. DNA \uc190\uc0c1 \ubcf5\uad6c\uc640 \uad00\ub828\ud558\uc5ec, \ub178\ud654\uc640 \uc678\ubd80 \ud658\uacbd \uc694\uc778\uc758 \uc601\ud5a5\uc73c\ub85c \uc138\ud3ec DNA\ub294 \uc190\uc0c1\uc774 \ucd95\uc801\ub429\ub2c8\ub2e4. NMN\uc774 NAD+ \uc218\uce58\ub97c \uc99d\uac00\uc2dc\ud0a4\uba74, \ud65c\uc131\ud654\ub41c \uc2dc\ub974\ud22c\uc778\uc740 \uad00\ub828 DNA \ubcf5\uad6c \ud6a8\uc18c\ub97c \ud65c\uc131\ud654\ud558\uc5ec \uc190\uc0c1\ub41c DNA \uc870\uac01\uc744 \uc815\ud655\ud558\uac8c \ucc3e\uc544\ub0b4 \ubcf5\uad6c\ud558\uace0, \uc720\uc804 \uc815\ubcf4\uc758 \uc815\ud655\ud55c \uc804\ub2ec\uc744 \ubcf4\uc7a5\ud558\uba70 \uc815\uc0c1\uc801\uc778 \uc138\ud3ec \uae30\ub2a5\uc744 \uc720\uc9c0\ud569\ub2c8\ub2e4.<\/p>\n

\uc138\ud3ec\uc758 “\uc5d0\ub108\uc9c0 \uacf5\uc7a5”\uc778 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 \uc138\ud3ec\uc758 \ud65c\ub825\uc744 \uc9c1\uc811\uc801\uc73c\ub85c \uacb0\uc815\ud569\ub2c8\ub2e4. NMN\uc740 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ud638\ud761 \uc0ac\uc2ac\uc758 \ud6a8\uc728\uc131\uc744 \ud5a5\uc0c1\uc2dc\ucf1c \ud2b8\ub9ac\uce74\ub974\ubcf5\uc2e4\uc0b0 \ud68c\ub85c\ub97c \ub354\uc6b1 \uc6d0\ud65c\ud558\uac8c \ud558\uace0 \ub354 \ub9ce\uc740 ATP\ub97c \uc0dd\uc131\ud558\uc5ec \uc138\ud3ec\uc5d0 \ucda9\ubd84\ud55c \uc5d0\ub108\uc9c0\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \ub354\uc6b1\uc774 NMN\uc740 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc758 \ud56d\uc0b0\ud654 \ubc29\uc5b4 \uc2dc\uc2a4\ud15c\uc744 \uac15\ud654\ud558\uc5ec \ud65c\uc131 \uc0b0\uc18c(ROS) \ucd95\uc801\uc744 \uc904\uc774\uace0 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc640 \uc138\ud3ec\uc758 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4. \ud558\ubc84\ub4dc \uc758\ub300\uc5d0\uc11c \uc2e4\uc2dc\ud55c \uace0\uc804\uc801\uc778 \uc2e4\ud5d8\uc5d0\uc11c, \ub178\ub839 \ub9c8\uc6b0\uc2a4\uc5d0\uac8c \uc9c0\uc18d\uc801\uc778 NMN \ubcf4\ucda9\uc740 \uadfc\uc9c0\uad6c\ub825\uc744 \ub180\ub78d\uac8c \ud5a5\uc0c1\uc2dc\ucf30\uc2b5\ub2c8\ub2e4. \ud2b8\ub808\ub4dc\ubc00 \uc2e4\ud5d8\uc5d0\uc11c, \ub9c8\uc6b0\uc2a4\uc758 \uc6b4\ub3d9 \uc2dc\uac04\uacfc \uac70\ub9ac\ub294 \ub300\uc870\uad70\uc5d0 \ube44\ud574 \uc720\uc758\ubbf8\ud558\uac8c \uc99d\uac00\ud588\uc2b5\ub2c8\ub2e4. \ud53c\ubd80 \ud0c4\ub825 \ub610\ud55c \uc720\uc758\ubbf8\ud558\uac8c \uac1c\uc120\ub418\uc5c8\uc73c\uba70, \ucf5c\ub77c\uac90 \ud568\ub7c9\uc774 \uc99d\uac00\ud558\uace0 \uc8fc\ub984\uc774 \uac10\uc18c\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc9c0\ud45c\uc5d0 \ub300\ud55c \uc885\ud569\uc801\uc778 \ud3c9\uac00 \uacb0\uacfc, \ub9c8\uc6b0\uc2a4\uc758 \ub178\ud654 \uacfc\uc815\uc774 20% \uc5ed\uc804\ub418\uc5c8\uc73c\uba70, \uc774\ub294 \ud56d\ub178\ud654 \ubd84\uc57c\uc5d0\uc11c NMN\uc758 \ub180\ub77c\uc6b4 \ud6a8\ub2a5\uc744 \uac15\ub825\ud558\uac8c \uc785\uc99d\ud569\ub2c8\ub2e4. \ubd84\uc790\uc801 \uc5f0\uad6c \uacb0\uacfc, NMN\uc740 \uc55e\uc11c \uc5b8\uae09\ud55c \uacbd\ub85c\ub97c \ud1b5\ud574 \uc138\ud3ec \ub178\ud654 \uacfc\uc815\uc5d0 \uc9c1\uc811\uc801\uc778 \uc601\ud5a5\uc744 \ubbf8\uce60 \ubfd0\ub9cc \uc544\ub2c8\ub77c \ud154\ub85c\ubbf8\uc5b4 \ubcf4\ud638 \ubc0f \uc624\ud1a0\ud30c\uc9c0 \ud65c\uc131\ud654\uc640 \uac19\uc740 \uc5ec\ub7ec \ud575\uc2ec \ub178\ud654 \uac1c\uc785 \ud45c\uc801\uc5d0\ub3c4 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc5fc\uc0c9\uccb4 \ub9d0\ub2e8\uc758 \ubcf4\ud638 \ucea1\uc778 \ud154\ub85c\ubbf8\uc5b4\ub294 \uc138\ud3ec \ubd84\uc5f4\uacfc \ud568\uaed8 \ub2e8\ucd95\ub429\ub2c8\ub2e4. \ud154\ub85c\ubbf8\uc5b4\uac00 \uc77c\uc815 \uc218\uc900\uae4c\uc9c0 \uc9e7\uc544\uc9c0\uba74 \uc138\ud3ec\ub294 \ub178\ud654 \ub610\ub294 \uc138\ud3ec\uc790\uba78\uc0ac \uc0c1\ud0dc\uc5d0 \ub4e4\uc5b4\uac11\ub2c8\ub2e4. NMN\uc740 \uad00\ub828 \ud154\ub85c\uba38\ub77c\uc81c\ub97c \ud65c\uc131\ud654\ud558\uc5ec \ud154\ub85c\ubbf8\uc5b4 \uae38\uc774\ub97c \uc720\uc9c0\ud558\uace0 \uc138\ud3ec \ub178\ud654\ub97c \uc9c0\uc5f0\uc2dc\ud0b5\ub2c8\ub2e4. \uc790\uac00\ud3ec\uc2dd\uacfc \uad00\ub828\ud558\uc5ec, NMN\uc5d0 \uc758\ud574 \u200b\u200b\ud65c\uc131\ud654\ub418\ub294 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub294 \uc138\ud3ec\uac00 \uc190\uc0c1\ub41c \uc138\ud3ec\uc18c\uae30\uad00\uacfc \ub2e8\ubc31\uc9c8 \uc751\uc9d1\uccb4\ub97c \uc2e0\uc18d\ud558\uac8c \uc81c\uac70\ud558\ub3c4\ub85d \ucd09\uc9c4\ud558\uc5ec \uae68\ub057\ud558\uace0 \ud56d\uc0c1\uc131\uc744 \uc720\uc9c0\ud558\ub294 \uc138\ud3ec \ub0b4 \ud658\uacbd\uc744 \uc720\uc9c0\ud558\uace0 \uc138\ud3ec \uc7ac\uc0dd\uc5d0 \uae30\uc5ec\ud569\ub2c8\ub2e4.<\/p>\n

(II) \ub300\uc0ac \ubc0f \uc7a5\uae30 \uae30\ub2a5 \uc870\uc808<\/h3>\n

\ub300\uc0ac \uac74\uac15:<\/strong> NMN\uc740 \ub300\uc0ac \uac74\uac15 \uc870\uc808\uc5d0 \uc0c1\ub2f9\ud55c \ud6a8\uacfc\ub97c \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uc624\uc0ac\uce74 \ub300\ud559\uad50\uc5d0\uc11c \uc2e4\uc2dc\ud55c \ub300\ud45c\uc801\uc778 \uc784\uc0c1 \uc5f0\uad6c\uc5d0\ub294 \ube44\uc815\uc0c1\uc801\uc778 \ub300\uc0ac \uc9c0\ud45c\ub97c \uac00\uc9c4 \uc5ec\ub7ec \ud53c\ud5d8\uc790\ub4e4\uc5d0\uac8c 3\uac1c\uc6d4 \ub3d9\uc548 \ub9e4\uc77c 250mg\uc758 NMN \ubcf4\ucda9\uc81c\ub97c \ud22c\uc5ec\ud588\uc2b5\ub2c8\ub2e4. \uadf8 \uacb0\uacfc\ub294 \ub180\ub77c\uc6e0\uc2b5\ub2c8\ub2e4. \ud53c\ud5d8\uc790\ub4e4\uc758 \uc778\uc290\ub9b0 \ubbfc\uac10\ub3c4\uac00 19% \ud06c\uac8c \uc99d\uac00\ud588\ub294\ub370, \uc774\ub294 \uc138\ud3ec\uac00 \uc778\uc290\ub9b0\uc5d0 \ub354 \uc798 \ubc18\uc751\ud558\uace0 \ud608\uc911 \ud3ec\ub3c4\ub2f9\uc744 \ub354 \ud6a8\uc728\uc801\uc73c\ub85c \ud761\uc218\ud558\uace0 \ud65c\uc6a9\ud568\uc73c\ub85c\uc368 \ud608\ub2f9 \uc218\uce58\ub97c \uc548\uc815\ud654\uc2dc\ud0a4\uace0 \ub2f9\ub1e8\ubcd1\uacfc \uac19\uc740 \ub300\uc0ac \uc9c8\ud658\uc758 \uc704\ud5d8\uc744 \uac10\uc18c\uc2dc\ucf30\uc74c\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. \uc911\uc131\uc9c0\ubc29 \uc218\uce58 \ub610\ud55c 15% \uac10\uc18c\ud588\uc2b5\ub2c8\ub2e4. \ud608\uc911 \uc9c0\uc9c8\uc758 \ud575\uc2ec \uc131\ubd84\uc778 \uc911\uc131\uc9c0\ubc29 \uac10\uc18c\ub294 \uc9c0\uc9c8 \ub300\uc0ac \uc7a5\uc560\ub97c \uac1c\uc120\ud558\uace0 \uc9c0\ubc29\uac04 \ubc0f \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\uc99d\uacfc \uac19\uc740 \uc9c8\ubcd1\uc758 \uc704\ud5d8\uc744 \uac10\uc18c\uc2dc\ud0a4\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub300\uc0ac \uacbd\ub85c \uad00\uc810\uc5d0\uc11c, NMN\uc740 NAD+ \uc218\uce58\ub97c \uc99d\uac00\uc2dc\ucf1c \ud3ec\ub3c4\ub2f9 \ubc0f \uc9c0\uc9c8 \ub300\uc0ac\uc5d0 \uad00\uc5ec\ud558\ub294 \uc77c\ub828\uc758 \ud575\uc2ec \ud6a8\uc18c\uc640 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \ud65c\uc131\ud654\ud569\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uac04\uc5d0\uc11c \uc9c0\ubc29\uc0b0 \uc0b0\ud654 \ud6a8\uc18c\uc758 \ud65c\uc131\uc744 \uc99d\uac00\uc2dc\ucf1c \uc9c0\ubc29 \ubd84\ud574\ub97c \ucd09\uc9c4\ud558\uace0 \uc9c0\ubc29 \ucd95\uc801\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \ub610\ud55c \uc778\uc290\ub9b0 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc870\uc808\ud558\uc5ec \uc778\uc290\ub9b0 \ud6a8\uacfc\ub97c \ub192\uc774\uace0 \ud608\ub2f9 \ub300\uc0ac\ub97c \ucd5c\uc801\ud654\ud569\ub2c8\ub2e4. \uc2ec\ud608\uad00 \ubcf4\ud638: NMN\uc740 \uc2ec\ud608\uad00\uacc4\uc5d0 \ub300\ud55c \ub2e4\uc591\ud558\uace0 \uc2ec\uce35\uc801\uc778 \ubcf4\ud638 \uc791\uc6a9 \uae30\uc804\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ub0b4\ud53c \uae30\ub2a5 \uac1c\uc120\uacfc \uad00\ub828\ud558\uc5ec, \ub0b4\ud53c \uc138\ud3ec\uc5d0\uc11c \uc77c\uc0b0\ud654\uc9c8\uc18c(NO) \ubc29\ucd9c\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4. NO\ub294 \ud608\uad00 \ud3c9\ud65c\uadfc\uc744 \uc774\uc644\uc2dc\ud0a4\uace0 \ud608\uad00\uc744 \ud655\uc7a5\uc2dc\ud0a4\ub294 \uac15\ub825\ud55c \ud608\uad00 \ud655\uc7a5\uc81c\ub85c, \ud608\uc555\uc744 \ub0ae\ucd94\uace0 \ud608\uad00 \ud0c4\ub825\uc131\uc744 \uc99d\uac00\uc2dc\ud0a4\uba70 \uc2ec\ud608\uad00 \uc9c8\ud658\uc758 \uc704\ud5d8\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 NMN \ubcf4\ucda9\uc81c\ub294 \ub0b4\ud53c\uc138\ud3ec\uc5d0\uc11c \uc77c\uc0b0\ud654\uc9c8\uc18c \ud569\uc131\ud6a8\uc18c(eNOS)\uc758 \ud65c\uc131\uc744 \uc99d\uac00\uc2dc\ud0a4\uace0 \uc77c\uc0b0\ud654\uc9c8\uc18c(NO) \uc0dd\uc131\uc744 \uc720\uc758\ubbf8\ud558\uac8c \uc99d\uac00\uc2dc\ucf1c \ub0b4\ud53c\uc138\ud3ec \uae30\ub2a5 \uc7a5\uc560\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \uac1c\uc120\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\uc99d\uc740 \uc2ec\ud608\uad00 \uc9c8\ud658\uc758 \uc8fc\uc694 \ubcd1\ub9ac\ud559\uc801 \uc6d0\uc778\uc785\ub2c8\ub2e4. NMN\uc740 \uc5fc\uc99d\uc744 \uc5b5\uc81c\ud558\uace0 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub97c \uac10\uc18c\uc2dc\ucf1c \ub3d9\ub9e5\uacbd\ud654\uc99d \uc9c0\uc218\ub97c \uc720\uc758\ubbf8\ud558\uac8c \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \ub3d9\ubb3c \uc5f0\uad6c\uc5d0\uc11c, \ub178\ub839 \ub9c8\uc6b0\uc2a4\uc5d0\uac8c NMN \ubcf4\ucda9\uc81c\ub97c \ud22c\uc5ec\ud55c \uacb0\uacfc \ud608\uad00\ubcbd\uc758 \uc5fc\uc99d \uc138\ud3ec \uce68\uc724\uc774 \uac10\uc18c\ud558\uace0, \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \uc9c0\ud45c \uc218\uce58\uac00 \ub0ae\uc544\uc84c\uc73c\uba70, \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\ubc18 \ud615\uc131\uc774 \ud6a8\uacfc\uc801\uc73c\ub85c \uc5b5\uc81c\ub418\uc5c8\uace0, \ud608\uad00\ubcbd\uc758 \ud0c4\ub825\uc131\uacfc \uc720\uc5f0\uc131\uc774 \uc720\uc758\ubbf8\ud558\uac8c \uac1c\uc120\ub418\uc5c8\uc2b5\ub2c8\ub2e4. 2023\ub144 Scientific Reports\uc5d0 \ubc1c\ud45c\ub41c \uc5f0\uad6c\uc5d0\uc11c\ub294 NMN\uc774 \ud608\uad00 \ub0b4\ubcbd\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc744 \uc9c1\uc811\uc801\uc73c\ub85c \ud655\uc778\ud588\uc2b5\ub2c8\ub2e4 \uc815\uc0c1 \ud608\uc555\uc740 \uc911\uac15\ub3c4 \uc6b4\ub3d9\uacfc \uc720\uc0ac\ud569\ub2c8\ub2e4. \uc774 \ubc1c\uacac\uc740 \uc2e0\uccb4\uc801 \uc81c\uc57d\uc73c\ub85c \uaddc\uce59\uc801\uc778 \uc6b4\ub3d9\uc744 \ud558\uae30 \uc5b4\ub824\uc6b4 \uc0ac\ub78c\ub4e4\uc5d0\uac8c \uc2ec\ud608\uad00 \uac74\uac15 \uc720\uc9c0\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \uc811\uadfc\ubc95\uc744 \uc81c\uc2dc\ud569\ub2c8\ub2e4. NMN \ubcf4\ucda9\uc81c\ub294 \ud608\uc555 \uac15\ud558 \ubc0f \ud608\uad00 \uae30\ub2a5 \uac1c\uc120\uacfc \uac19\uc774 \uc6b4\ub3d9\uacfc \uc720\uc0ac\ud55c \uc2ec\ud608\uad00\uc801 \ud6a8\uacfc\ub97c \uc5bb\uc744 \uc218 \uc788\ub294 \uc7a0\uc7ac\ub825\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc2ec\ud608\uad00 \uc9c8\ud658\uc758 \uc608\ubc29 \ubc0f \ubcf4\uc870 \uce58\ub8cc\uc5d0 \uc0c8\ub85c\uc6b4 \uae38\uc744 \uc5f4\uc5b4\uc90d\ub2c8\ub2e4.<\/p>\n

\uc2e0\uacbd \ubcf4\ud638:<\/strong> \uc2e0\uacbd \ubcf4\ud638 \ubd84\uc57c\uc5d0\uc11c NMN\uc758 \uc791\uc6a9 \uae30\uc804\uc740 \ub178\uc778\uc758 \uc778\uc9c0 \uae30\ub2a5\uc744 \uc2ec\uac01\ud558\uac8c \uc190\uc0c1\uc2dc\ud0a4\ub294 \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658\uc778 \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc5d0 \ub300\ud55c \uc5f0\uad6c\uc758 \ud070 \uad00\uc2ec\uc0ac\uc785\ub2c8\ub2e4. \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc758 \uc8fc\uc694 \ubcd1\ub9ac\ud559\uc801 \ud2b9\uc9d5 \uc911 \ud558\ub098\ub294 \ub1cc\uc5d0 \ubca0\ud0c0 \uc544\ubc00\ub85c\uc774\ub4dc \ub2e8\ubc31\uc9c8\uc774 \ube44\uc815\uc0c1\uc801\uc73c\ub85c \ucd95\uc801\ub418\ub294 \uac83\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud50c\ub77c\ud06c\ub294 \ub274\ub7f0 \uac04\uc758 \uc5f0\uacb0\uc744 \ubc29\ud574\ud558\uace0 \uc2e0\uacbd \uc2e0\ud638 \uc804\ub2ec\uc744 \ubc29\ud574\ud558\uba70 \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4. NMN\uc740 \uad00\ub828 \ub300\uc0ac \uacbd\ub85c\uc640 \uc720\uc804\uc790 \ubc1c\ud604\uc744 \uc870\uc808\ud558\uc5ec \ubca0\ud0c0 \uc544\ubc00\ub85c\uc774\ub4dc \ub2e8\ubc31\uc9c8\uc758 \ubd84\ud574 \ubc0f \uc81c\uac70\ub97c \ucd09\uc9c4\ud558\uace0 \ub1cc\uc5d0 \ucd95\uc801\ub418\ub294 \uac83\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c, NMN\uc740 \uc2dc\ub0c5\uc2a4 \uac00\uc18c\uc131\uc744 \ud5a5\uc0c1\uc2dc\ucf1c \ub274\ub7f0 \uac04\uc758 \uc5f0\uacb0\uc744 \uac15\ud654\ud558\uace0 \uc2e0\ud638 \uc804\ub2ec \ud6a8\uc728\uc744 \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc2dc\ub0c5\uc2a4 \uac00\uc18c\uc131\uc740 \ud559\uc2b5\uacfc \uae30\uc5b5\uc758 \uc2e0\uacbd\uc0dd\ubb3c\ud559\uc801 \uae30\ucd08\uc785\ub2c8\ub2e4. NMN\uc740 \uad00\ub828 \uc2e0\ud638 \uc804\ub2ec \ubd84\uc790\uc640 \ub2e8\ubc31\uc9c8 \ud0a4\ub098\uc544\uc81c\ub97c \ud65c\uc131\ud654\uc2dc\ucf1c \uc2dc\ub0c5\uc2a4\uc758 \uc131\uc7a5, \ubc1c\ub2ec \ubc0f \uc720\uc9c0\ub97c \ucd09\uc9c4\ud558\uace0, \uc2e0\uacbd \uc804\ub2ec\uc744 \uac1c\uc120\ud558\uc5ec \uc778\uc9c0 \ub2a5\ub825\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. Nature Neuroscience\uc5d0 \uac8c\uc7ac\ub41c \uc774 \uc5f0\uad6c \uacb0\uacfc\ub294 \uc2e0\uacbd \ubcf4\ud638 \ubc0f \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc758 \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \uc788\uc5b4 NMN\uc758 \uc5ed\ud560\uc5d0 \ub300\ud55c \uac15\ub825\ud55c \uc774\ub860\uc801 \uadfc\uac70\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \ub610\ud55c \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \uce58\ub8cc \uc804\ub7b5 \uac1c\ubc1c\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \ud76c\ub9dd\uc744 \uc81c\uc2dc\ud569\ub2c8\ub2e4. \uc544\ub9c8\ub3c4 \ubbf8\ub798\uc5d0 NMN\uc740 \uc54c\uce20\ud558\uc774\uba38\ubcd1\uacfc \uac19\uc740 \uc2e0\uacbd \uc9c8\ud658\uc758 \uc608\ubc29 \ubc0f \uc644\ud654\ub97c \uc704\ud55c \uc911\uc694\ud55c \ub3c4\uad6c\uac00 \ub420 \uc218 \uc788\uc744 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

(III) \uc7a0\uc7ac\uc801 \uc704\ud5d8 \ubc0f \ub17c\ub780<\/h3>\n

NMN\uc740 \uc218\ub9ce\uc740 \uae0d\uc815\uc801\uc778 \uac74\uac15\uc0c1\uc758 \uc774\uc810\uc744 \uc785\uc99d\ud588\uc9c0\ub9cc, \uc7a5\uae30\uac04 \uc12d\ucde8\uc5d0\ub294 \uc7a0\uc7ac\uc801 \uc704\ud5d8\uc774 \ub530\ub985\ub2c8\ub2e4. \ub300\uc0ac\uc0b0\ubb3c\uacfc \uad00\ub828\ud558\uc5ec, NMN\uc740 \ub300\uc0ac \uacfc\uc815\uc5d0\uc11c \ub2c8\ucf54\ud2f4\uc544\ub9c8\uc774\ub4dc(NAM)\ub97c \uc0dd\uc131\ud569\ub2c8\ub2e4. \uc7a5\uae30\uac04 \uace0\uc6a9\ub7c9 NMN \ubcf4\ucda9\uc81c\ub294 NAM \ucd95\uc801\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub3d9\ubb3c \uc5f0\uad6c\uc5d0\uc11c \uc774\uc5d0 \ub300\ud55c \uac15\ub825\ud55c \uc99d\uac70\uac00 \uc81c\uc2dc\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uace0\uc6a9\ub7c9 NMN \ubcf4\ucda9\uc81c(1000mg\/kg\/\uc77c \uc774\uc0c1)\ub294 \uc2e4\ud5d8 \ub3d9\ubb3c\uc5d0\uc11c \uac04 \uc9c0\ubc29\uc99d\uc744 \uc720\ubc1c\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uacfc\ub3c4\ud55c NAM\uc774 \uac04\uc758 \uc9c0\uc9c8 \ub300\uc0ac \uacbd\ub85c\ub97c \ubc29\ud574\ud558\uc5ec \uac04\uc138\ud3ec \ub0b4 \ube44\uc815\uc0c1\uc801\uc778 \uc9c0\ubc29 \ucd95\uc801\uc744 \uc720\ubc1c\ud558\uace0 \uc815\uc0c1\uc801\uc778 \uac04 \uae30\ub2a5\uc744 \uc190\uc0c1\uc2dc\ud0a4\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \uc7a5\uae30\uac04 \ucd95\uc801\uc740 \ube44\uc54c\ucf54\uc62c\uc131 \uc9c0\ubc29\uac04\uacfc \uac19\uc740 \uac04 \uc9c8\ud658\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uac1c\uc778\ucc28 \ub610\ud55c \uc911\uc694\ud55c \ubb38\uc81c\uc785\ub2c8\ub2e4. \uc778\uccb4\uc758 NMN \ud761\uc218 \ubc0f \uc774\uc6a9 \ud6a8\uc728\uc740 NMNAT \ud6a8\uc18c \ud65c\uc131\uc758 \ucc28\uc774\ub85c \uc778\ud574 \ud06c\uac8c \ub2e4\ub985\ub2c8\ub2e4. NMNAT \ud6a8\uc18c\ub294 NMN\uc744 NAD+\ub85c \uc804\ud658\ud558\ub294 \ucd09\ub9e4 \uc791\uc6a9\uc744 \ud569\ub2c8\ub2e4. \uc720\uc804\uc801 \ub2e4\ud615\uc131 \ubc0f \uae30\ud0c0 \uc694\uc778\uc73c\ub85c \uc778\ud574 \uc77c\ubd80 \uc0ac\ub78c\ub4e4\uc740 \uccb4\ub0b4 NMNAT \ud6a8\uc18c \ud65c\uc131\uc774 \ub0ae\uc544 NMN\uc744 NAD+\ub85c \uc804\ud658\ud558\ub294 \ud6a8\uc728\uc774 \ub5a8\uc5b4\uc9c0\uace0 \ud761\uc218 \ud6a8\uc728\uc774 \ub5a8\uc5b4\uc9d1\ub2c8\ub2e4. \uc774\ub85c \uc778\ud574 \ub3d9\uc77c\ud55c \uc6a9\ub7c9\uc758 NMN \ubcf4\ucda9\uc81c\ub97c \uc12d\ucde8\ud558\ub354\ub77c\ub3c4 \uac1c\uc778\ub9c8\ub2e4 \ud6a8\uacfc\uac00 \ud06c\uac8c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4. \uc5b4\ub5a4 \uc0ac\ub78c\ub4e4\uc740 NMN\uc73c\ub85c \uc778\ud574 \uc0c1\ub2f9\ud55c \uac74\uac15 \uac1c\uc120\uc744 \uacbd\ud5d8\ud558\ub294 \ubc18\uba74, \uc5b4\ub5a4 \uc0ac\ub78c\ub4e4\uc740 \ubbf8\ubbf8\ud55c \ud6a8\uacfc\ub97c \uacbd\ud5d8\ud558\uac70\ub098, \uc2ec\uc9c0\uc5b4 \ud6a8\uacfc \uc5c6\ub294 \ubcf4\ucda9\uc81c \uc12d\ucde8\ub85c \uc778\ud574 \uc624\ud574\ub098 \ubd88\ub9cc\uc871\uc744 \ub290\ub07c\uae30\ub3c4 \ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubb38\uc81c\ub294 NMN\uc758 \uad11\ubc94\uc704\ud55c \uc801\uc6a9\uacfc \uc815\ud655\ud55c \uac1c\uc785\uc5d0 \uc5b4\ub824\uc6c0\uc744 \uc57c\uae30\ud569\ub2c8\ub2e4. \uac1c\uc778\uc758 \ub300\uc0ac \ucc28\uc774\uc5d0 \uae30\ubc18\ud55c \ub9de\ucda4\ud615 NMN \ubcf4\ucda9\uc81c \uc694\ubc95 \uac1c\ubc1c\uc740 \ud5a5\ud6c4 \uc5f0\uad6c\uc758 \ud575\uc2ec \ubd84\uc57c\uc785\ub2c8\ub2e4.<\/p>\n

\uc2dc\uc7a5 \ud604\ud669 \ubc0f \uc0b0\uc5c5 \uc0dd\ud0dc\uacc4: \ubb34\uc81c\ud55c \uc131\uc7a5\uc5d0\uc11c \uaddc\uc81c\ub41c \ubc1c\uc804\uc73c\ub85c<\/h2>\n

\"\"<\/p>\n

\uae00\ub85c\ubc8c \uc2dc\uc7a5 \ud658\uacbd \ubc0f \uae30\uc220 \ubc1c\uc804 \ubc29\ud5a5<\/h3>\n

\uc804 \uc138\uacc4\uc801\uc73c\ub85c NMN \uc2dc\uc7a5\uc740 \uae09\uc131\uc7a5\ud558\uace0 \uc788\uc73c\uba70 \ub9c9\ub300\ud55c \uc7a0\uc7ac\ub825\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \uc804\ubb38 \uc2dc\uc7a5 \uc870\uc0ac \uae30\uad00\uc758 \uc608\uce21\uc5d0 \ub530\ub974\uba74, \uae00\ub85c\ubc8c NMN \uc2dc\uc7a5\uc740 2025\ub144\uae4c\uc9c0 120\uc5b5 \ub2ec\ub7ec \uaddc\ubaa8\ub85c \uae09\uc131\uc7a5\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uae09\uc18d\ud55c \uc131\uc7a5\uc740 \uac74\uac15 \ubd84\uc57c\uc5d0\uc11c NMN\uc758 \uc778\uae30\uac00 \ub192\uc544\uc9c0\uace0 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \uc2dc\uc7a5 \ubd84\ud3ec \uce21\uba74\uc5d0\uc11c\ub294, \ub6f0\uc5b4\ub09c \uacfc\ud559 \uc5f0\uad6c \uc5ed\ub7c9\uacfc \uc131\uc219\ud55c \uac74\uac15 \uc0b0\uc5c5 \uc2dc\uc2a4\ud15c\uc744 \uac16\ucd98 \uc77c\ubcf8\uacfc \ubbf8\uad6d\uc774 \uace0\uae09 NMN \uc2dc\uc7a5\uc744 \uc7a5\uc545\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc77c\ubcf8 \uae30\uc5c5\ub4e4\uc740 \uc81c\ud488 \ud488\uc9c8\uacfc R&D \ud601\uc2e0\uc5d0 \uc9d1\uc911\ud558\uace0 \uc788\uc73c\uba70, \uc774\ub4e4\uc758 NMN \uc81c\ud488\uc740 \ub192\uc740 \ud488\uc9c8\uacfc \uc21c\ub3c4\ub85c \uc815\ud3c9\uc774 \ub098 \uc788\uc5b4 \uc18c\ube44\uc790\uc758 \uc2e0\ub8b0\ub97c \uc5bb\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ubbf8\uad6d\uc740 \uacfc\ud559 \uc5f0\uad6c \ubc0f \ub9c8\ucf00\ud305 \uc5ed\ub7c9\uc5d0 \ub300\ud55c \uc801\uadf9\uc801\uc778 \ud22c\uc790\ub97c \ud1b5\ud574 NMN \uae30\uc220 \uac1c\ubc1c \ubc0f \uc2dc\uc7a5 \ud655\ub300\uc5d0 \uc0c1\ub2f9\ud55c \uc131\uacf5\uc744 \uac70\ub450\uc5c8\uc73c\uba70, \uc218\ub9ce\uc740 \uc720\uba85 \ube0c\ub79c\ub4dc\uac00 \ubbf8\uad6d \uc2dc\uc7a5\uc5d0 \uc9c4\ucd9c\ud558\uc5ec \uc804 \uc138\uacc4\ub85c \ud655\uc7a5\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.
\n\ud604\uc7ac NMN \uc0dd\uc0b0\uc744 \uc704\ud55c \uc138 \uac00\uc9c0 \uc8fc\uc694 \uae30\uc220 \uacbd\ub85c\uac00 \ub4f1\uc7a5\ud588\uc73c\uba70, \uac01\uac01 \uace0\uc720\ud55c \uc7a5\uc810\uacfc \ud2b9\uc131\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc8fc\ub958 \uae30\uc220 \uc911 \ud558\ub098\uc778 \uc0dd\ud6a8\uc18c\ubc95\uc740 \uc0c1\ub2f9\ud55c \uc7a5\uc810\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc774\uc169\ud558\uc624 21000\uc740 99.9% \uc774\uc0c1\uc758 \ub9e4\uc6b0 \ub192\uc740 \uc21c\ub3c4\ub97c \uc790\ub791\ud558\uba70, \ucd5c\uace0\uc758 \ud488\uc9c8\uacfc \uc548\uc804\uc131\uc744 \ubcf4\uc7a5\ud569\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uc774\uc169\ud558\uc624 21000\uc740 \ubc14\uc774\uc624 \ud6a8\uc18c\ubc95\uc744 \uc0ac\uc6a9\ud558\uc5ec \uc0dd\uc0b0\ub418\uba70, \uc21c\ub3c4 99.99%\ub97c \ub2ec\uc131\ud558\uace0 \uc5c4\uaca9\ud55c \uc81c3\uc790 \uc778\uc99d\uc744 \ud1b5\uacfc\ud588\uc2b5\ub2c8\ub2e4. \ub610\ud55c, \uc0dd\uc0b0 \uacfc\uc815\uc5d0\uc11c \ucca8\ub2e8 \ud6a8\uc18c \uc720\ub3c4 \uc9c4\ud654 \uae30\uc220\uc744 \uc0ac\uc6a9\ud558\uc5ec \uc2e0\uccb4\uc758 NMN \uc790\uc5f0 \ud569\uc131 \uacfc\uc815\uc744 \ubaa8\ubc29\ud558\uc5ec \ud761\uc218 \ubc0f \ud65c\uc6a9\uc744 \uc6a9\uc774\ud558\uac8c \ud558\uace0, NMN\uc758 \uc0dd\ubb3c\ud559\uc801 \ud65c\uc131\uacfc \ud6a8\ub2a5\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \ud654\ud559\uc801 \ud569\uc131\uc740 \uc800\ube44\uc6a9\uc774\ub77c\ub294 \uc7a5\uc810\uc744 \uc81c\uacf5\ud558\uc5ec \uc81c\ud488 \uac00\uaca9\uc744 \ub0ae\ucd94\uace0 \uc2dc\uc7a5 \uacbd\uc7c1\ub825\uc744 \uac15\ud654\ud560 \uc218 \uc788\uc9c0\ub9cc, \uc774 \ubc29\ubc95\uc73c\ub85c \uc0dd\uc0b0\ub41c NMN\uc740 \ub192\uc740 \uc218\uc900\uc758 \ubd88\uc21c\ubb3c\uc744 \ud568\uc720\ud558\uace0 \uc788\uc5b4 \uc81c\ud488\uc758 \uc548\uc804\uc131\uacfc \ud6a8\ub2a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubd88\uc21c\ubb3c\uc740 \uccb4\ub0b4\uc5d0\uc11c \ubd80\uc791\uc6a9\uc744 \uc720\ubc1c\ud558\uace0, NMN\uc758 \uc21c\ub3c4\uc640 \ud65c\uc131\uc744 \uac10\uc18c\uc2dc\ucf1c \uccb4\ub0b4 \ub300\uc0ac \ubc0f \ud6a8\ub2a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ubc1c\ud6a8\ub294 \uc9c0\uc18d \uac00\ub2a5\ud55c \uac1c\ubc1c\uc774\ub77c\ub294 \uac1c\ub150\uc5d0 \ubd80\ud569\ud558\ub294 \uce5c\ud658\uacbd\uc801\uc778 \uc0dd\uc0b0 \ubc29\uc2dd\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc774 \ubc29\ubc95\uc740 \ud604\uc7ac \uc218\uc728\uc774 \uc81c\ud55c\uc801\uc774\uc5b4\uc11c \uc0dd\uc0b0 \ube44\uc6a9\uc774 \uc0c1\ub300\uc801\uc73c\ub85c \ub192\uace0 \ub300\uaddc\ubaa8 \uc2dc\uc7a5 \uc218\uc694\ub97c \ucda9\uc871\ud558\ub294 \ub370 \uc5b4\ub824\uc6c0\uc744 \uacaa\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ubc1c\ud6a8 \uacfc\uc815\uc5d0\uc11c \ubbf8\uc0dd\ubb3c\uc758 \uc131\uc7a5\uacfc \ub300\uc0ac\ub294 \ub2e4\uc591\ud55c \uc694\uc778\uc758 \uc601\ud5a5\uc744 \ubc1b\uc544 NMN \uc0dd\uc0b0\ub7c9\uc744 \ud06c\uac8c \ub298\ub9ac\uae30 \uc5b4\ub824\uc6cc \uad11\ubc94\uc704\ud55c \uc2dc\uc7a5 \uc801\uc6a9\uc774 \uc81c\ud55c\ub429\ub2c8\ub2e4.<\/p>\n

\uc911\uad6d \uae30\uc5c5\ub4e4\uc740 NMN \ubd84\uc57c\uc5d0 \ub300\ud55c R&D \ud22c\uc790\ub97c \uc9c0\uc18d\uc801\uc73c\ub85c \ub298\ub9ac\uace0 \uc788\uc73c\uba70, \uae30\uc220 \ud601\uc2e0\uc744 \ud1b5\ud574 \ud68d\uae30\uc801\uc778 \ubc1c\uc804\uc744 \uc774\ub8e8\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ubc14\uc774\uc624 \ud6a8\uc18c \uae30\uc220 \ubd84\uc57c\uc5d0\uc11c \uc0c1\ub2f9\ud55c \uc9c4\uc804\uc744 \uc774\ub8e8\uc5b4 \uc6d0\uc790\uc7ac \ube44\uc6a9\uc744 37% \uc808\uac10\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ube44\uc6a9 \uc808\uac10\uc73c\ub85c NMN \uc81c\ud488\uc758 \uc2dc\uc7a5 \uac00\uaca9 \uacbd\uc7c1\ub825\uc774 \uac15\ud654\ub418\uc5b4 \ub354 \ub9ce\uc740 \uc18c\ube44\uc790\uc5d0\uac8c \ud61c\ud0dd\uc744 \uc81c\uacf5\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc911\uad6d \uae30\uc5c5\ub4e4\uc758 \uc774\ub7ec\ud55c \uae30\uc220\uc801 \ud601\uc2e0\uc740 \uc138\uacc4 NMN \uc2dc\uc7a5\uc5d0\uc11c\uc758 \uc785\uc9c0\ub97c \uac15\ud654\ud588\uc744 \ubfd0\ub9cc \uc544\ub2c8\ub77c, NMN \uc81c\ud488\uc758 \uad11\ubc94\uc704\ud55c \ucc44\ud0dd \ubc0f \uc801\uc6a9\uc744 \ucd09\uc9c4\ud558\uc5ec \uc0b0\uc5c5 \uc804\uccb4\uc758 \ubc1c\uc804\uc744 \ucd09\uc9c4\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uacfc\ud559\uc801 \uc0ac\uc6a9 \uac00\uc774\ub4dc: \ubcf5\uc6a9\ub7c9, \uc870\ud569 \ubc0f \uad6c\ub9e4 \uc804\ub7b5<\/h2>\n

\"\"<\/p>\n

(I) \uc548\uc804\ud55c \ubcf5\uc6a9\ub7c9 \ubc0f \uc801\ud569\ud55c \ub300\uc0c1<\/h3>\n

\uac74\uac15\ud55c \uc131\uc778\uc758 \uacbd\uc6b0, NMN \ubcf4\ucda9\uc81c\uc758 \uad8c\uc7a5 \uc77c\uc77c \ubcf5\uc6a9\ub7c9\uc740 200~500mg\uc785\ub2c8\ub2e4. \uc774 \ubcf5\uc6a9\ub7c9 \ubc94\uc704\ub294 \uad11\ubc94\uc704\ud55c \uacfc\ud559\uc801 \uc5f0\uad6c\uc640 \uc784\uc0c1 \uc2dc\ud5d8\uc744 \uae30\ubc18\uc73c\ub85c \ud569\ub2c8\ub2e4. \uc2e4\uc81c\ub85c NMN\uc758 \ud761\uc218 \ubc0f \ud65c\uc6a9\uc744 \ub192\uc774\uae30 \uc704\ud574 \uc2dd\uc0ac\uc640 \ud568\uaed8 1\ud68c \ub610\ub294 2\ud68c\ub85c \ub098\ub204\uc5b4 \ubcf5\uc6a9\ud558\ub294 \uac83\uc774 \uc88b\uc2b5\ub2c8\ub2e4. \uc2dd\uc0ac\uc640 \ud568\uaed8 NMN\uc744 \ubcf5\uc6a9\ud558\uba74 \uc704\uc7a5\uad00 \ub0b4 \ud658\uacbd\uc744 \ubd80\ub4dc\ub7fd\uac8c \uc870\uc131\ud558\uc5ec \uc704\uc0b0\uc73c\ub85c \uc778\ud55c NMN \uc190\uc0c1\uc744 \uc644\ud654\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c NMN\uc774 \uc74c\uc2dd\uc758 \uc601\uc591\uc18c\uc640 \uc0c1\uc2b9\uc801\uc73c\ub85c \uc0c1\ud638 \uc791\uc6a9\ud558\uc5ec \uc0dd\uccb4 \uc774\uc6a9\ub960\uc744 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4.<\/p>\n

NMN\uc758 \uc801\ud569\uc131\uc740 \ub300\uc0c1\uad70\uc5d0 \ub530\ub77c \ub2e4\ub974\ubbc0\ub85c \uc8fc\uc758\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \uc784\uc0b0\ubd80\uc640 \uc218\uc720\ubd80\ub294 \ud2b9\ubcc4\ud55c \uc0dd\ub9ac\uc801 \uc0c1\ud0dc\uc5d0 \uc788\uc73c\uba70, \ud0dc\uc544\ub098 \uc720\uc544\uc5d0\uac8c NMN\uc774 \ubbf8\uce60 \uc218 \uc788\ub294 \uc7a0\uc7ac\uc801 \uc601\ud5a5\uc740 \uc54c\ub824\uc838 \uc788\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc7a0\uc7ac\uc801 \uc704\ud5d8\uc744 \ud53c\ud558\uae30 \uc704\ud574 NMN \uc12d\ucde8\ub97c \uc5c4\uaca9\ud788 \ud53c\ud574\uc57c \ud569\ub2c8\ub2e4. \ubbf8\uc131\ub144\uc790\ub294 \uc131\uc7a5\uacfc \ubc1c\ub2ec\uc5d0 \uc911\uc694\ud55c \uc2dc\uae30\ub97c \uacaa\uace0 \uc788\uc73c\uba70, NAD+ \uc218\uce58\uac00 \ube44\uad50\uc801 \ucda9\ubd84\ud558\uace0 \uc790\uccb4 \ub300\uc0ac \uccb4\uacc4\uac00 \uc815\uc0c1\uc801\uc778 \uc131\uc7a5 \uc694\uad6c\ub97c \ucda9\uc871\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c NMN \ubcf4\ucda9\uc81c\ub294 \uc544\ubb34\ub7f0 \ud6a8\uacfc\ub97c \uc81c\uacf5\ud558\uc9c0 \ubabb\ud560 \ubfd0\ub9cc \uc544\ub2c8\ub77c \uc815\uc0c1\uc801\uc778 \uc131\uc7a5\uacfc \ubc1c\ub2ec\uc744 \ubc29\ud574\ud558\uc5ec \uc801\ud569\ud558\uc9c0 \uc54a\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uac04 \ubc0f \uc2e0\uc7a5 \uc9c8\ud658 \ud658\uc790\uc758 \uacbd\uc6b0, \uac04\uacfc \uc2e0\uc7a5 \ub300\uc0ac \uae30\ub2a5 \uc7a5\uc560\ub85c \uc778\ud574 NMN \ub300\uc0ac \ubc0f \ubc30\uc124\uc5d0 \uc601\ud5a5\uc744 \ubc1b\uc544 \uac04\uacfc \uc2e0\uc7a5\uc758 \ubd80\ub2f4\uc774 \uc99d\uac00\ud558\uace0 \uc0c1\ud0dc\uac00 \uc545\ud654\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c NMN \ub610\ud55c \ud53c\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\ub2f9\ub1e8\ubcd1 \ud658\uc790\ub294 NMN \ubcf4\ucda9\uc81c \uc12d\ucde8\ub97c \uace0\ub824\ud560 \ub54c \ub9e4\uc6b0 \uc8fc\uc758\ud574\uc57c \ud569\ub2c8\ub2e4. NMN\uc740 \uc5b4\ub290 \uc815\ub3c4 \uc2e0\uc9c4\ub300\uc0ac\ub97c \uc870\uc808\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\uc9c0\ub9cc, \ud608\ub2f9\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. NMN \ubcf4\ucda9\uc81c \uc12d\ucde8 \uc2dc \ub2f9\ub1e8\ubcd1 \ud658\uc790\ub294 \ud608\ub2f9 \uc218\uce58\ub97c \uba74\ubc00\ud788 \ubaa8\ub2c8\ud130\ub9c1\ud558\uc5ec \uce58\ub8cc \uacc4\ud68d\uc744 \uc2e0\uc18d\ud558\uac8c \uc870\uc815\ud574\uc57c \ud569\ub2c8\ub2e4. \ub610\ud55c, \uba54\ud2b8\ud3ec\ub974\ubbfc\uacfc \uac19\uc740 \ud608\ub2f9 \uac15\ud558\uc81c\ub97c \ubcf5\uc6a9\ud558\ub294 \ub2f9\ub1e8\ubcd1 \ud658\uc790\ub294 NMN\uacfc \ubcd1\uc6a9 \ud22c\uc5ec\ub97c \ud53c\ud574\uc57c \ud569\ub2c8\ub2e4. \uba54\ud2b8\ud3ec\ub974\ubbfc\uc740 \uc8fc\ub85c \uac04\uc758 \ud3ec\ub3c4\ub2f9 \uc0dd\uc131\uc744 \uc5b5\uc81c\ud558\uace0 \ub9d0\ucd08 \uc870\uc9c1\uc758 \ud3ec\ub3c4\ub2f9 \ud761\uc218 \ubc0f \uc774\uc6a9\uc744 \uc99d\uac00\uc2dc\ucf1c \ud608\ub2f9\uc744 \ub0ae\ucda5\ub2c8\ub2e4. NMN\uc758 \ub300\uc0ac \uacbd\ub85c \uc870\uc808\uc740 \uba54\ud2b8\ud3ec\ub974\ubbfc\uc758 \uc791\uc6a9 \uae30\uc804\uc744 \ubc29\ud574\ud558\uc5ec \ud6a8\ub2a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\uace0 \uc800\ud608\ub2f9\uacfc \uac19\uc740 \ubd80\uc791\uc6a9\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. 2025\ub144 Frontiers in Nutrition\uc5d0 \ubc1c\ud45c\ub41c 6\uac1c\uc6d4 \ucd94\uc801 \uc5f0\uad6c\ub294 NMN\uc758 \uc548\uc804\uc131\uc5d0 \ub300\ud55c \uac15\ub825\ud55c \uc99d\uac70\ub97c \uc81c\uc2dc\ud588\uc2b5\ub2c8\ub2e4. \uc774 \uc5f0\uad6c\ub294 \ub9e4\uc77c 500mg\uc758 NMN\uc744 \ubcf5\uc6a9\ud558\ub294 \uac74\uac15\ud55c \ud53c\ud5d8\uc790 \uadf8\ub8f9\uc744 \ub300\uc0c1\uc73c\ub85c \ud588\uc2b5\ub2c8\ub2e4. \ucd94\uc801 \uae30\uac04 \ub3d9\uc548 \ud53c\ud5d8\uc790\uc758 \uc2e0\uccb4 \uc9c0\ud45c\ub97c \uc885\ud569\uc801\uc73c\ub85c \ubaa8\ub2c8\ud130\ub9c1\ud55c \uacb0\uacfc, 500mg\/\uc77c \ubcf5\uc6a9 \uadf8\ub8f9\uc5d0\uc11c \ud2b8\ub79c\uc2a4\uc544\ubbf8\ub098\uc81c \uc0c1\uc2b9\uacfc \uac19\uc740 \ub3c5\uc131 \ubc18\uc751\uc774 \ubc1c\uc0dd\ud558\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc774 \uc6a9\ub7c9\uc5d0\uc11c NMN\uc758 \uc548\uc804\uc131\uc744 \uc785\uc99d\ud558\uba70, \uc18c\ube44\uc790\uac00 NMN \uc6a9\ub7c9\uc744 \uc120\ud0dd\ud560 \ub54c \uc911\uc694\ud55c \uc9c0\uce68\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n

(II) \uac15\ud654 \uacc4\ud68d \ubc0f \uc131\ubd84 \ud638\ud658\uc131<\/h3>\n

\ud761\uc218 \ucd5c\uc801\ud654:<\/strong> \uc7a5\uc6a9 \ucf54\ud305 \uc81c\ud615\uc744 \uc120\ud0dd\ud558\ub294 \uac83\uc740 NMN \ud761\uc218\ub97c \ud5a5\uc0c1\uc2dc\ud0a4\ub294 \ud575\uc2ec \uc804\ub7b5\uc785\ub2c8\ub2e4. \uc7a5\uc6a9 \ucf54\ud305 \uc81c\ud615\uc740 \uc704\uc0b0\uc758 \uc190\uc0c1\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \ubc29\uc9c0\ud558\ub294 \ud2b9\uc218 \ucf54\ud305 \uae30\uc220\uc744 \uc0ac\uc6a9\ud569\ub2c8\ub2e4. \uc5f0\uad6c \ub370\uc774\ud130\uc5d0 \ub530\ub974\uba74 \uace0\ud488\uc9c8 \uc7a5\uc6a9 \ucf54\ud305 \uc81c\ud615\uc758 \uc704\uc0b0 \ubd84\ud574\uc728\uc740 5% \ubbf8\ub9cc\uc73c\ub85c \uc81c\uc5b4\ub418\uc5b4 \ub354 \ub9ce\uc740 NMN\uc774 \uc704\ub97c \ud1b5\uacfc\ud558\uc5ec \uc18c\uc7a5\uc5d0 \ub3c4\ub2ec\ud558\uc5ec \ud761\uc218\ub420 \uc218 \uc788\uc74c\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. \uc18c\uc7a5\uc740 \uc601\uc591\uc18c \ud761\uc218\uc758 \uc8fc\uc694 \ubd80\uc704\uc774\uba70, NMN\uc740 \uc18c\uc7a5\uc5d0\uc11c \ud608\ub958\ub85c \ub354 \ud6a8\uc728\uc801\uc73c\ub85c \ud761\uc218\ub418\uc5b4 \uc0dd\uccb4\uc774\uc6a9\ub960\uc744 \ub192\uc785\ub2c8\ub2e4. \uc7a5\uc6a9 \ucf54\ud305 \uc81c\ud615 \uc678\uc5d0\ub3c4, \ud751\ud6c4\ucd94 \ucd94\ucd9c\ubb3c\uacfc \ud568\uaed8 \uc0ac\uc6a9\ud558\ub294 \uac83\ub3c4 \ud6a8\uacfc\uc801\uc778 \ud761\uc218 \ucd5c\uc801\ud654 \ubc29\ubc95\uc785\ub2c8\ub2e4. \ud751\ud6c4\ucd94 \ucd94\ucd9c\ubb3c\uc5d0\ub294 \ud53c\ud398\ub9b0\uc774 \ud568\uc720\ub418\uc5b4 \uc788\uc5b4 NMN \ud761\uc218\ub97c \ud06c\uac8c \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ud53c\ud398\ub9b0\uc740 NMN \ud761\uc218\ub97c 30%\uae4c\uc9c0 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud53c\ud398\ub9b0\uc740 \uc7a5 \uc138\ud3ec \ub0b4 \uc218\uc1a1 \ub2e8\ubc31\uc9c8\uc758 \ud65c\uc131\uc744 \uc870\uc808\ud558\uc5ec NMN\uacfc \uc774\ub7ec\ud55c \uc218\uc1a1\uccb4\uc758 \uacb0\ud569\uc744 \uc99d\uac00\uc2dc\ud0a4\uace0 \ub9c9 \ud1b5\uacfc\ub97c \ucd09\uc9c4\ud558\uc5ec NMN\uc758 \ud761\uc218 \ubc0f \ud65c\uc6a9\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4.<\/p>\n

\uc2dc\ub108\uc9c0 \ud6a8\uacfc:<\/strong> NMN\uacfc \ub2e4\ub978 \uc131\ubd84\uc758 \uc2dc\ub108\uc9c0 \ud6a8\uacfc\ub97c \ud1b5\ud574 \ub354\uc6b1 \uac15\ub825\ud55c \uac74\uac15 \ud6a8\uacfc\ub97c \uc81c\uacf5\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. NMN\uacfc PQQ(\ud53c\ub864\ub85c\ud034\ub180\ub9b0\ud034\ub17c)\uc758 \uc870\ud569\uc740 \ub9ce\uc740 \uad00\uc2ec\uc744 \ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4. PQQ\ub294 \uc138\ud3ec \ub300\uc0ac\uc640 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \uc870\uc808\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \uc0c8\ub85c\uc6b4 \uc218\uc6a9\uc131 \ube44\ud0c0\ubbfc\uc785\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 NMN\uacfc PQQ\ub97c \ubcd1\uc6a9\ud558\uba74 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc0dd\ud569\uc131\uc744 40%\uae4c\uc9c0 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 PQQ\uac00 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc0dd\ud569\uc131\uacfc \uad00\ub828\ub41c \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \ud65c\uc131\ud654\ud558\uc5ec \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc99d\uc2dd\uacfc \uae30\ub2a5 \ud5a5\uc0c1\uc744 \ucd09\uc9c4\ud558\uace0, NMN\uc774 \uc81c\uacf5\ud558\ub294 NAD+\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc5d0\ub108\uc9c0 \ub300\uc0ac\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \uc774 \ub450 \uac00\uc9c0\uac00 \ud568\uaed8 \uc791\uc6a9\ud558\uba74 \uc138\ud3ec \uc5d0\ub108\uc9c0 \uacf5\uae09\uacfc \ub300\uc0ac \ud65c\ub3d9\uc774 \ud5a5\uc0c1\ub429\ub2c8\ub2e4. NMN\uacfc \ucf54\uc5d4\uc790\uc784 Q10\uc758 \ubcd1\uc6a9 \ub610\ud55c \uc0c1\ub2f9\ud55c \uc774\uc810\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \ucf54\uc5d4\uc790\uc784 Q10\uc740 \uc778\uac04 \uc138\ud3ec\uc5d0\uc11c \ubc1c\uacac\ub418\ub294 \ucc9c\uc5f0 \ud56d\uc0b0\ud654\uc81c\uc774\uba70 \uc2ec\uc7a5 \uc5d0\ub108\uc9c0 \ub300\uc0ac\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. NMN\uacfc \ucf54\uc5d4\uc790\uc784 Q10\uc744 \ubcd1\uc6a9\ud558\uba74 \uc2ec\uc7a5 \uc5d0\ub108\uc9c0 \uacf5\uae09\uc744 25%\uae4c\uc9c0 \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc2ec\uc7a5 \uc138\ud3ec\uc5d0\uc11c \ucf54\uc5d4\uc790\uc784 Q10\uc740 \uc804\uc790 \uc804\ub2ec\uc5d0 \uad00\uc5ec\ud569\ub2c8\ub2e4 \uc0ac\uc2ac\uc744 \ud65c\uc131\ud654\ud558\uc5ec ATP \uc0dd\uc131\uc744 \ucd09\uc9c4\ud558\ub294 \ub3d9\uc2dc\uc5d0, NMN\uc758 NAD+ \uc218\uce58 \uc99d\uac00\ub294 \uc5d0\ub108\uc9c0 \ub300\uc0ac\ub97c \ub354\uc6b1 \ucd5c\uc801\ud654\ud569\ub2c8\ub2e4. \uc774 \ub450 \uc131\ubd84\uc740 \uc2dc\ub108\uc9c0 \ud6a8\uacfc\ub97c \ubc1c\ud718\ud558\uc5ec \uc2ec\uc7a5\uc5d0 \ub354 \ub9ce\uc740 \uc5d0\ub108\uc9c0\ub97c \uacf5\uae09\ud558\uace0, \uc815\uc0c1\uc801\uc778 \uc2ec\uc7a5 \uae30\ub2a5\uc744 \uc720\uc9c0\ud558\uba70 \uc2ec\ud608\uad00 \uc9c8\ud658 \uc704\ud5d8\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \ud604\uc7ac NMN\uacfc \uc774\ub7ec\ud55c \uc131\ubd84\uc758 \uc870\ud569\uc740 \uc5ec\ub7ec \ud2b9\ud5c8\ub97c \ubc1b\uc558\uc73c\uba70, \uc774\ub294 \uacfc\ud559\uc801\uc774\uace0 \ud601\uc2e0\uc801\uc778 \ud2b9\uc131\uc744 \uc778\uc815\ubc1b\uc558\uc744 \ubfd0\ub9cc \uc544\ub2c8\ub77c \uc18c\ube44\uc790\uc5d0\uac8c \ub354\uc6b1 \uac80\uc99d\ub41c \uace0\ud488\uc9c8 \uc81c\ud488 \uc635\uc158\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n

\uae08\uae30 \uc0ac\ud56d:<\/strong> NMN \ubcf5\uc6a9 \uc2dc \ub2c8\uc544\uc2e0(\ube44\ud0c0\ubbfc B3)\uacfc \ud568\uaed8 \ubcf5\uc6a9\ud558\uc9c0 \uc54a\ub3c4\ub85d \uc8fc\uc758\ud558\uc2ed\uc2dc\uc624. \ub2c8\uc544\uc2e0\uc740 \uccb4\ub0b4 NAD+ \ud569\uc131\uc5d0\ub3c4 \uad00\uc5ec\ud569\ub2c8\ub2e4. NMN\uacfc \ub2c8\uc544\uc2e0\uc744 \ud568\uaed8 \ubcf5\uc6a9\ud558\uba74 NAD+ \ud569\uc131 \uacbd\ub85c\uc758 \uacbd\uc7c1\uc801 \uc5b5\uc81c\uac00 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ub450 \uc131\ubd84\uc774 NAD+ \ud569\uc131 \uacfc\uc815\uc5d0\uc11c \ub3d9\uc77c\ud55c \ud6a8\uc18c\uc640 \uae30\uc9c8\uc5d0 \ub300\ud574 \uacbd\uc7c1\ud558\uc5ec NAD+ \ud569\uc131\uc758 \uc815\uc0c1\uc801\uc778 \ud6a8\uc728\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc0c1\ud638 \uc791\uc6a9\uc744 \ubc29\uc9c0\ud558\ub824\uba74 \ub450 \uc131\ubd84\uc744 \ucd5c\uc18c 2\uc2dc\uac04 \uac04\uaca9\uc744 \ub450\uace0 \ubcf5\uc6a9\ud574\uc57c \ud569\ub2c8\ub2e4. \uc774\ub97c \ud1b5\ud574 \uc2e0\uccb4\ub294 NMN\uacfc \ub2c8\uc544\uc2e0\uc744 \uac01\uac01 \ub300\uc0ac\ud558\uace0 \ud65c\uc6a9\ud560 \ucda9\ubd84\ud55c \uc2dc\uac04\uc744 \ud655\ubcf4\ud558\uc5ec \uc6d0\ud65c\ud55c NAD+ \ud569\uc131 \uacbd\ub85c\ub97c \ud655\ubcf4\ud558\uace0 NMN\uacfc \ub2c8\uc544\uc2e0\uc758 \uac74\uac15\uc0c1\uc758 \uc774\uc810\uc744 \uc628\uc804\ud788 \ub204\ub9b4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

(III) \ud65c\uc131\ud615 \uad6c\ub9e4\ub97c \uc704\ud55c \ud575\uc2ec \uc9c0\ud45c<\/h3>\n

\ud65c\uc131\ud615:<\/strong> NMN \uc81c\ud488\uc744 \uad6c\ub9e4\ud560 \ub54c \uac00\uc7a5 \uba3c\uc800 \uace0\ub824\ud574\uc57c \ud560 \uac83\uc740 \ud65c\uc131\ud615\uc785\ub2c8\ub2e4. “\u03b2-NMN”\uc774\ub77c\uace0 \ud45c\uc2dc\ub41c \uc81c\ud488\ub9cc \uc0dd\ubb3c\ud559\uc801 \ud65c\uc131\uc744 \uac00\uc9c0\uba70 \uc2e0\uccb4\uc5d0\uc11c \ud6a8\uacfc\uc801\uc73c\ub85c \ud65c\uc6a9\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \u03b2-NMN\uc740 NMN\uc758 \ud65c\uc131 \uc774\uc131\uc9c8\uccb4\uc785\ub2c8\ub2e4. \u03b2-NMN\uc758 \ubd84\uc790 \uad6c\uc870\ub294 \uc778\uac04 \uc138\ud3ec \ub0b4 \uad00\ub828 \ud6a8\uc18c \ubc0f \uc218\uc1a1\uccb4\uc5d0 \ud2b9\uc774\uc801\uc73c\ub85c \uacb0\ud569\ud558\uc5ec \ub300\uc0ac \uacfc\uc815\uc5d0 \ucc38\uc5ec\ud558\uace0 NAD+ \uc218\uce58\ub97c \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4. \ubc18\uba74, \u03b1-NMN\uc740 \uc774\ub7ec\ud55c \uc0dd\ubb3c\ud559\uc801 \ud65c\uc131\uc774 \ubd80\uc871\ud558\uc5ec NMN\uc758 \uc774\uc810\uc744 \uc81c\uacf5\ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4. \uc77c\ubd80 \uc545\ub355 \ud310\ub9e4\uc790\ub4e4\uc740 \u03b1-NMN\uc744 \uc81c\ud488\uc5d0 \uc11e\uc5b4 \ud310\ub9e4\ud569\ub2c8\ub2e4. \uc18c\ube44\uc790\ub294 \uc774\ub7ec\ud55c \ube44\ud6a8\uacfc\uc801\uc778 \uc81c\ud488\uc744 \uad6c\ub9e4\ud558\uc9c0 \uc54a\ub3c4\ub85d \uc81c\ud488 \ub77c\ubca8\uc744 \uc8fc\uc758 \uae4a\uac8c \ud655\uc778\ud558\uace0, \uad6c\ub9e4\ud558\ub294 NMN\uc774 \uc9c4\uc815\ud55c \ud65c\uc131\ud615 \u03b2-NMN\uc778\uc9c0 \ud655\uc778\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\uc21c\ub3c4 \uc778\uc99d:<\/strong> \uc81c\ud488 \uc21c\ub3c4\ub294 NMN \ud488\uc9c8\uc758 \ud575\uc2ec \uc9c0\ud45c\uc785\ub2c8\ub2e4. SGS\/HPLC \uc2dc\ud5d8 \uc131\uc801\uc11c\uc640 99% \uc774\uc0c1\uc758 \uc21c\ub3c4\ub97c \ubcf4\uc720\ud55c \uc81c\ud488\uc774 \uc120\ud638\ub429\ub2c8\ub2e4. SGS\ub294 \uad6d\uc81c\uc801\uc73c\ub85c \uc778\uc815\ubc1b\ub294 \uac80\uc0ac, \uc2dd\ubcc4, \uc2dc\ud5d8 \ubc0f \uc778\uc99d \uae30\uad00\uc774\uba70, SGS\uc758 \uc2dc\ud5d8 \uc131\uc801\uc11c\ub294 \ub9e4\uc6b0 \uad8c\uc704 \uc788\uace0 \uc2e0\ub8b0\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. HPLC(\uace0\uc131\ub2a5 \uc561\uccb4 \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c)\ub294 NMN \uc81c\ud488\uc758 \uc21c\ub3c4\ub97c \uc815\ud655\ud558\uac8c \uce21\uc815\ud558\ub294 \ucca8\ub2e8 \ubd84\uc11d \uae30\uc220\uc785\ub2c8\ub2e4. \uace0\uc21c\ub3c4 NMN \uc81c\ud488\uc740 \uc77c\ubc18\uc801\uc73c\ub85c 0.1% \ubbf8\ub9cc\uc758 \ub9e4\uc6b0 \ub0ae\uc740 \ubd88\uc21c\ubb3c \ud568\ub7c9\uc744 \uac00\uc9c0\uace0 \uc788\uc5b4 \uc778\uccb4\uc5d0 \ub300\ud55c \uc7a0\uc7ac\uc801\uc778 \uc720\ud574\uc131\uc744 \ud06c\uac8c \uc904\uc785\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uace0\ud488\uc9c8 NMN \uc81c\ud488\uc740 \uc911\uae08\uc18d \ud568\ub7c9\uc774 1ppm \uc774\ud558\uc774\uc5b4\uc57c \ud569\ub2c8\ub2e4. \uc81c\ud488 \uc548\uc804\uacfc \uc18c\ube44\uc790 \uc2e0\ub8b0\ub97c \ubcf4\uc7a5\ud558\uae30 \uc704\ud574 \uc911\uae08\uc18d \ubc0f \uae30\ud0c0 \uc720\ud574 \ubb3c\uc9c8\uc758 \uc794\ub958 \uc218\uc900\uc744 \uc5c4\uaca9\ud558\uac8c \uad00\ub9ac\ud569\ub2c8\ub2e4.<\/p>\n

\uc0dd\uc0b0 \uacf5\uc815:<\/strong> \uc0dd\uc0b0 \uacf5\uc815\uc740 NMN \uc81c\ud488\uc758 \ud488\uc9c8\uacfc \uc548\uc804\uc131\uc5d0 \uc9c1\uc811\uc801\uc778 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \ud6a8\uc18c\ubc95\uc740 \ud654\ud559 \ud569\uc131\uc5d0 \ube44\ud574 \uc0c1\ub2f9\ud55c \uc774\uc810\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \ud6a8\uc18c\ubc95\uc740 \uc2e0\uccb4\uc758 \uc790\uc5f0\uc801\uc778 NMN \ud569\uc131 \uacfc\uc815\uc744 \ubaa8\ubc29\ud558\uc5ec \ud2b9\uc815 \ud6a8\uc18c\ub97c \ucd09\ub9e4\ub85c \uc0ac\uc6a9\ud558\uace0 \uc628\ud654\ud55c \uc870\uac74\uc5d0\uc11c \ubc18\uc751\uc744 \uc9c4\ud589\ud569\ub2c8\ub2e4. \uc774 \ubc29\ubc95\uc73c\ub85c \uc0dd\uc0b0\ub41c NMN\uc740 \uace0\uc21c\ub3c4, \uace0\ud65c\uc131, \uadf8\ub9ac\uace0 \ud654\ud559 \uc794\ub958\ubb3c\uc774 \uac70\uc758 \uc5c6\uc5b4 \uc778\uccb4\uc758 \uc0dd\ub9ac\uc801 \uc694\uad6c\uc5d0 \ub354\uc6b1 \ubd80\ud569\ud569\ub2c8\ub2e4. \uc81c\ud488\uc744 \uc120\ud0dd\ud560 \ub54c\ub294 “\ud640\ub85c\uc5d4\uc790\uc784 \ucd09\ub9e4” \ubc0f “\uc9c0\uc2dc \uc9c4\ud654”\uc640 \uac19\uc740 \ucca8\ub2e8 \ubc14\uc774\uc624 \ud6a8\uc18c \uae30\uc220 \ud0a4\uc6cc\ub4dc\ub97c \ud65c\uc6a9\ud558\ub294\uc9c0 \ud655\uc778\ud558\uc2ed\uc2dc\uc624. \ud640\ub85c\uc5d4\uc790\uc784 \ucd09\ub9e4 \uae30\uc220\uc740 \ubc18\uc751 \uacfc\uc815\uc744 \ub354\uc6b1 \uc815\ubc00\ud558\uac8c \uc81c\uc5b4\ud558\uc5ec NMN \ud569\uc131\uc758 \ud6a8\uc728\uc131\uacfc \ud488\uc9c8\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \uc9c0\uc2dc \uc9c4\ud654 \uae30\uc220\uc740 \ud6a8\uc18c\ub97c NMN \uc0dd\uc0b0\uc5d0 \ub354\uc6b1 \uc801\ud569\ud558\ub3c4\ub85d \ubcc0\ud615 \ubc0f \ucd5c\uc801\ud654\ud558\uc5ec \uc81c\ud488 \ud488\uc9c8\uc744 \ub354\uc6b1 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \ud654\ud559 \ud569\uc131\uc740 \ube44\uc6a9\uc774 \uc800\ub834\ud558\uc9c0\ub9cc, \uc0dd\uc0b0 \uacfc\uc815\uc5d0\uc11c \ub9ce\uc740 \uc591\uc758 \ud654\ud559 \uc2dc\uc57d\uc744 \uc0ac\uc6a9\ud560 \uc218 \uc788\uc5b4 \ud654\ud559 \uc794\ub958\ubb3c\uc774 \uc27d\uac8c \uc0dd\uc131\ub418\uace0 \uc778\uccb4 \uac74\uac15\uc5d0 \ud2b9\uc815 \uc704\ud5d8\uc744 \ucd08\ub798\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c NMN \uc81c\ud488\uc744 \uad6c\ub9e4\ud560 \ub54c\ub294 \ud654\ud559 \ud569\uc131 \uc0ac\uc6a9\uc744 \ud53c\ud558\uc2ed\uc2dc\uc624.<\/p>\n

\ubbf8\ub798 \uc804\ub9dd: \ub17c\ub780\uc758 \uc5ec\uc9c0\uac00 \uc788\ub294 \uae30\uc220 \ud601\uc2e0\uacfc \uc0b0\uc5c5 \uc5c5\uadf8\ub808\uc774\ub4dc\"\"<\/h2>\n

(I) \ucd5c\ucca8\ub2e8 \uae30\uc220 \ubc29\ud5a5<\/h3>\n

\uc804\ub2ec \uc2dc\uc2a4\ud15c \ud601\uc2e0:<\/strong> \ub9ac\ud3ec\uc880 \ucea1\uc290\ud654 \uae30\uc220\uc740 NMN \uc804\ub2ec \uc2dc\uc2a4\ud15c \ud601\uc2e0\uc5d0 \uc0c1\ub2f9\ud55c \uc7a0\uc7ac\ub825\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \ub9ac\ud3ec\uc880\uc740 \uc778\uc9c0\uc9c8 \uc774\uc911\uce35\uc73c\ub85c \uad6c\uc131\ub41c \ub098\ub178\uc785\uc790\ub85c, \ub6f0\uc5b4\ub09c \uc0dd\uccb4\uc801\ud569\uc131\uacfc \ud45c\uc801 \ud2b9\uc131\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \ub9ac\ud3ec\uc880 \ub0b4\uc5d0 NMN\uc744 \ucea1\uc290\ud654\ud558\uba74 \uc704\uc0b0\uc5d0 \uc758\ud55c NMN\uc758 \ud30c\uad34\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \ubc29\uc9c0\ud558\uc5ec \uc704\uc7a5\uad00 \ub0b4 \uc548\uc815\uc131\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ub9ac\ud3ec\uc880 \ucea1\uc290\ud654\ub97c \uc0ac\uc6a9\ud55c NMN \uc81c\ud488\uc740 \uae30\uc874 \uc81c\ud488\ubcf4\ub2e4 \ud608\uc911 \ub18d\ub3c4\uac00 5\ubc30 \uc99d\uac00\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ub354 \ub9ce\uc740 NMN\uc774 \ud608\ub958\ub85c \ud761\uc218\ub418\uc5b4 \uc0dd\ubb3c\ud559\uc801 \ud65c\uc131\uc744 \ub354\uc6b1 \ud6a8\uacfc\uc801\uc73c\ub85c \ubc1c\ud718\ud560 \uc218 \uc788\uc74c\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. \ub098\ub178\uc785\uc790\ub97c \ud45c\uc801\uc73c\ub85c \ud558\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc804\ub2ec \uae30\uc220 \ub610\ud55c \uc0c1\ub2f9\ud55c \ubc1c\uc804\uc744 \uc774\ub8e8\uc5c8\uc2b5\ub2c8\ub2e4. \uc138\ud3ec\uc758 “\uc5d0\ub108\uc9c0 \ubc1c\uc804\uc18c”\uc778 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 NMN \ud65c\uc131\uc758 \ud575\uc2ec \ud45c\uc801\uc785\ub2c8\ub2e4. \ub098\ub178\uc785\uc790\ub97c \uc0ac\uc6a9\ud558\uc5ec NMN\uc744 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc5d0 \uc9c1\uc811 \uc804\ub2ec\ud558\uba74 NMN \uc804\ub2ec \ud6a8\uc728\uc744 \ud06c\uac8c \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \uc5f0\uad6c \uacb0\uacfc\ub294 Advanced Science\uc5d0 \uac8c\uc7ac\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc2e4\ud5d8 \ub370\uc774\ud130\uc5d0 \ub530\ub974\uba74 \uc774 \uae30\uc220\uc740 90% \uc774\uc0c1\uc758 \uc804\ub2ec \ud6a8\uc728\uc744 \ub2ec\uc131\ud558\uc5ec NMN\uc774 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub97c \ub354\uc6b1 \uc815\ud655\ud558\uac8c \ud45c\uc801\ud654\ud558\uace0, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5\uc744 \uac1c\uc120\ud558\uba70, \uc138\ud3ec\uc5d0 \ub354 \ub9ce\uc740 \uc5d0\ub108\uc9c0\ub97c \uacf5\uae09\ud558\uc5ec NMN\uc758 \ub178\ud654 \ubc29\uc9c0 \ubc0f \uac74\uac15 \uc720\uc9c0 \ud6a8\uacfc\ub97c \ub354\uc6b1 \ud5a5\uc0c1\uc2dc\ucf30\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud569\uc131 \uc0dd\ubb3c\ud559 \ud601\uc2e0:<\/strong> \uc911\uad6d \uacfc\ud559 \uc544\uce74\ub370\ubbf8\ub294 NMN \ud569\uc131 \uc0dd\ubb3c\ud559 \ubd84\uc57c\uc5d0\uc11c \ud68d\uae30\uc801\uc778 \ubc1c\uc804\uc744 \uc774\ub8e8\uc5c8\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\ud300\uc740 \ucca8\ub2e8 \uc720\uc804\uc790 \ud3b8\uc9d1 \uae30\uc220\uc744 \uc0ac\uc6a9\ud558\uc5ec \ub300\uc7a5\uade0\uc744 \uccb4\uacc4\uc801\uc73c\ub85c \uc870\uc791\ud558\uace0, \uc774 \uc138\uade0\uc5d0\uc11c \uc0c8\ub85c\uc6b4 NMN \ud569\uc131 \uacbd\ub85c\ub97c \uc131\uacf5\uc801\uc73c\ub85c \uac1c\ubc1c\ud588\uc2b5\ub2c8\ub2e4. \uc774 \ud601\uc2e0\uc801\uc778 \uae30\uc220\uc740 NMN \uc0dd\uc0b0\uc744 100\ubc30 \uc774\uc0c1 \uc99d\uac00\uc2dc\ucf1c NMN \uc0dd\uc0b0 \ud6a8\uc728\uc744 \ud06c\uac8c \ud5a5\uc0c1\uc2dc\ucf30\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \uc720\uc804\uc790 \ud3b8\uc9d1\uc744 \ud1b5\ud574 pncC \ubc0f nadR \uc720\uc804\uc790\ub97c \uc81c\uac70\ud588\uc2b5\ub2c8\ub2e4. \uc774 \uc911\uc694\ud55c \ub2e8\uacc4\ub294 NMN \ud569\uc131\uc5d0\uc11c \uacbd\uc7c1 \uacbd\ub85c\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \ucc28\ub2e8\ud558\uc5ec \ub354 \ub9ce\uc740 \uae30\uc9c8\uc774 NMN \ud569\uc131\uc5d0 \uc0ac\uc6a9\ub420 \uc218 \uc788\ub3c4\ub85d \ud558\uc5ec \uc0dd\uc0b0\uc744 \ud06c\uac8c \uc99d\uac00\uc2dc\ucf30\uc2b5\ub2c8\ub2e4. \uc774\ud6c4, \uc0c8\ub85c\uc6b4 NMN \ud569\uc131 \uacbd\ub85c\ub97c \ucd5c\uc801\ud654\ud558\uace0 NadV \ub9e4\uac1c NMN \uc0dd\ud569\uc131 \uacbd\ub85c\uc640 \ud1b5\ud569\ud558\uc5ec NMN \ud569\uc131 \ud6a8\uc728\uc744 \ub354\uc6b1 \ud5a5\uc0c1\uc2dc\ucf30\uc2b5\ub2c8\ub2e4. \ub450 \uac00\uc9c0 \uc218\uc1a1\uccb4\uc758 \ub3c4\uc785\uc73c\ub85c NAM \ud761\uc218\uc640 NMN \uc720\ucd9c\uc774 \ud5a5\uc0c1\ub418\uc5b4 NMN \uc0dd\uc0b0\ub7c9\uc774 \uc57d 1300\u03bcM\uc73c\ub85c \uc99d\uac00\ud588\uc2b5\ub2c8\ub2e4. PRPP \ud569\uc131\ud6a8\uc18c\ub97c \ucd5c\uc801\ud654\ud558\uace0 \ubcc0\ud615\ud568\uc73c\ub85c\uc368, 24\uc2dc\uac04 \uc9c4\ud0d5 \ud50c\ub77c\uc2a4\ud06c \ubc1c\ud6a8 \ud6c4 NMN \uc0dd\uc0b0\ub7c9\uc774 3000\u03bcM\uc744 \ucd08\uacfc\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud68d\uae30\uc801\uc778 \ubc1c\uc804\uc740 NMN \uc0dd\uc0b0\ub7c9\uc744 \ud06c\uac8c \uc99d\uac00\uc2dc\ucf30\uc744 \ubfd0\ub9cc \uc544\ub2c8\ub77c, \ud604\uc7ac \uc218\uc900\uc758 3\ubd84\uc758 1\ub85c \uac10\uc18c\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub418\ub294 \uc6d0\uc790\uc7ac \ube44\uc6a9\ub3c4 \ud06c\uac8c \uc808\uac10\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ube44\uc6a9 \uc808\uac10\uc740 NMN \uc81c\ud488\uc758 \uac00\uaca9\uc744 \ub354\uc6b1 \uc800\ub834\ud558\uac8c \ub9cc\ub4e4\uc5b4 NMN\uc758 \uad11\ubc94\uc704\ud55c \ub3c4\uc785\uc744 \uc704\ud55c \ud0c4\ud0c4\ud55c \uae30\ubc18\uc744 \ub9c8\ub828\ud558\uace0 \ub354 \ub9ce\uc740 \uc18c\ube44\uc790\uac00 NMN\uc758 \uac74\uac15\uc0c1\uc758 \uc774\uc810\uc744 \ub204\ub9b4 \uc218 \uc788\ub3c4\ub85d \ud560 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

(II) \uaddc\uc81c \ubc0f \uc0b0\uc5c5 \ud45c\uc900\ud654<\/h3>\n

\uc804 \uc138\uacc4\uc801\uc73c\ub85c \ubbf8\uad6d FDA\ub294 NMN\uc5d0 GRAS \uc548\uc804 \uc778\uc99d\uc744 \ubd80\uc5ec\ud558\uc5ec \ubbf8\uad6d \uc2dc\uc7a5\uc5d0\uc11c\uc758 \uac1c\ubc1c\uc744 \uac15\ub825\ud558\uac8c \uc9c0\uc6d0\ud558\uace0 NMN \uc81c\ud488\uc744 \uac74\uac15 \ubcf4\uc870 \uc2dd\ud488\uc73c\ub85c \ud569\ubc95\uc801\uc73c\ub85c \ud310\ub9e4\ud560 \uc218 \uc788\ub3c4\ub85d \ud588\uc2b5\ub2c8\ub2e4. \uc911\uad6d\uc5d0\uc11c\ub3c4 NMN \uc2dc\uc7a5\uc774 \uc9c0\uc18d\uc801\uc73c\ub85c \uc131\uc7a5\ud568\uc5d0 \ub530\ub77c \uaddc\uc81c \ub2f9\uad6d\uc740 \uc0b0\uc5c5 \uaddc\uc81c \ubc0f \ud45c\uc900\ud654\ub97c \uc801\uadf9\uc801\uc73c\ub85c \ucd94\uc9c4\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud604\uc7ac \uc911\uad6d\uc740 “NMN \uc6d0\ub8cc \ud488\uc9c8 \uae30\uc900” \uac1c\ubc1c\uc744 \uac00\uc18d\ud654\ud558\uace0 \uc788\uc73c\uba70, 2026\ub144\uc5d0\ub294 \uac74\uac15\uc2dd\ud488 \ub4f1\ub85d \uc81c\ub3c4\ub97c \ub3c4\uc785\ud560 \uc608\uc815\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc870\uce58\ub294 NMN \uc2dc\uc7a5\uc5d0 \ub300\ud55c \uac10\ub3c5\uc744 \uac15\ud654\ud558\uace0, \uc81c\ud488 \uc0dd\uc0b0 \ubc0f \ud310\ub9e4\ub97c \ud45c\uc900\ud654\ud558\uba70, \uc18c\ube44\uc790 \uad8c\ub9ac\ub97c \ubcf4\ud638\ud558\ub294 \uac83\uc744 \ubaa9\ud45c\ub85c \ud569\ub2c8\ub2e4. \uaddc\uc81c \uac15\ud654\ub97c \ud1b5\ud574 NMN \uc0b0\uc5c5\uc740 \uaddc\uc815 \uc900\uc218\uc640 \uae30\uc220 \ud601\uc2e0\uc744 \ub3d9\uc2dc\uc5d0 \uc911\uc2dc\ud558\ub294 \ub2e8\uacc4\ub85c \uc811\uc5b4\ub4e4 \uac83\uc785\ub2c8\ub2e4. \uaddc\uc815 \uc900\uc218\ub294 \uae30\uc5c5\uc758 \uc2dc\uc7a5 \uc9c4\uc785\uc5d0 \uadfc\ubcf8\uc801\uc778 \uc7a5\ubcbd\uc774 \ub420 \uac83\uc774\uba70, \uad00\ub828 \uae30\uc900\uacfc \uaddc\uc815\uc744 \ucda9\uc871\ud558\ub294 \uc81c\ud488\ub9cc\uc774 \uc2dc\uc7a5\uc5d0 \ucd9c\uc2dc\ub420 \uac83\uc785\ub2c8\ub2e4. \uae30\uc220 \ud601\uc2e0 \ub610\ud55c \uae30\uc5c5\uc758 \ud575\uc2ec \uacbd\uc7c1 \uc694\uc18c\ub85c \uc791\uc6a9\ud558\uc5ec \uc18c\ube44\uc790 \uc218\uc694\uc5d0 \ub9de\ucdb0 \uc81c\ud488\uc758 \ud488\uc9c8\uacfc \ud6a8\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uae30 \uc704\ud55c \uc9c0\uc18d\uc801\uc778 R&D \ud22c\uc790\ub97c \uc694\uad6c\ud560 \uac83\uc785\ub2c8\ub2e4. \uc774 \uacfc\uc815\uc5d0\uc11c \uc5c5\uacc4 \ub3c4\ud0dc\uc728\uc740 40%\uc5d0 \ub2ec\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4. \uae30\uc900\uc744 \ucda9\uc871\ud558\uc9c0 \ubabb\ud558\uace0 \uae30\uc220\uc774 \ub099\ud6c4\ub41c \uae30\uc5c5\uc740 \uc2dc\uc7a5\uc5d0\uc11c \ub3c4\ud0dc\ub418\ub294 \ubc18\uba74, \uaddc\uc815 \uc900\uc218\uc640 \uae30\uc220 \ud601\uc2e0\uc744 \uc911\uc2dc\ud558\ub294 \uae30\uc5c5\uc740 \ub3c4\ud0dc\ub418\uc5b4 \uc5c5\uacc4\uac00 \ub354\uc6b1 \uac74\uac15\ud558\uace0 \uc9c8\uc11c \uc788\ub294 \ubc1c\uc804\uc744 \uc774\ub8f0 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

(III) \uacfc\ud559\uc801 \ub17c\ub780\uacfc \ud569\ub9ac\uc801 \uc704\uce58<\/h3>\n

NMN\uc740 \ub3d9\ubb3c \uc5f0\uad6c\uc5d0\uc11c \uc218\uba85 \uc5f0\uc7a5, \ub300\uc0ac \uae30\ub2a5 \uac1c\uc120, \uc778\uc9c0 \ub2a5\ub825 \ud5a5\uc0c1 \ub4f1 \uc0c1\ub2f9\ud55c \ub178\ud654 \ubc29\uc9c0 \ud6a8\uacfc\ub97c \uc785\uc99d\ud588\uc9c0\ub9cc, \uc778\uac04(>5\ub144)\uc5d0 \ub300\ud55c \uc7a5\uae30\uc801\uc778 \uc548\uc804\uc131\uc5d0 \ub300\ud55c \ucd94\uac00 \ub370\uc774\ud130\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \ud604\uc7ac \uc778\uac04\uc5d0 \ub300\ud55c NMN\uc758 \uc7a5\uae30\uc801\uc778 \ud6a8\uacfc\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub294 \ube44\uad50\uc801 \uc81c\ud55c\uc801\uc774\uba70, \uc7a0\uc7ac\uc801\uc778 \uc704\ud5d8\uacfc \ubd80\uc791\uc6a9\uc740 \uc644\uc804\ud788 \uc774\ud574\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4. \uc7a5\uae30\uac04 \uace0\uc6a9\ub7c9 NMN \uc0ac\uc6a9\uc774 \uc778\uac04\uc758 \uba74\uc5ed \uccb4\uacc4, \uc0dd\uc2dd\uacc4 \ubc0f \uae30\ud0c0 \uae30\uad00\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294\uc9c0 \uc5ec\ubd80\ub294 \ucd94\uac00\uc801\uc778 \uc784\uc0c1 \uc5f0\uad6c\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \uc6b0\ub9ac\ub294 NMN\uc758 \uc5ed\ud560\uc5d0 \ud569\ub9ac\uc801\uc73c\ub85c \uc811\uadfc\ud574\uc57c \ud569\ub2c8\ub2e4. \ud575\uc2ec \uac00\uce58\ub294 NAD+ \uc218\uce58\ub97c \ub192\uc774\uace0, \uad00\ub828 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc640 \ub2e8\ubc31\uc9c8\uc744 \ud65c\uc131\ud654\ud558\uace0, \uc138\ud3ec \ub178\ud654\ub97c \uc9c0\uc5f0\uc2dc\ud0a4\uace0, \uc2e0\uccb4 \uae30\ub2a5\uc744 \uac1c\uc120\ud558\uc5ec “\ub178\ud654 \uacfc\uc815\uc5d0 \uac1c\uc785”\ud558\ub294 \uac83\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc9c8\ubcd1\uc744 \uce58\ub8cc\ud560 \uc218 \uc788\ub294 \uc57d\ubb3c\uc740 \uc544\ub2d9\ub2c8\ub2e4. \uac74\uac15\uacfc \ub178\ud654 \ubc29\uc9c0\ub97c \uc704\ud574 NMN\uc740 \uac74\uac15\ud55c \uc2dd\ub2e8\uacfc \uc801\ub2f9\ud55c \uc6b4\ub3d9\uacfc \uac19\uc740 \uc0dd\ud65c \uc2b5\uad00 \uad00\ub9ac\uc640 \uacb0\ud569\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4. \uade0\ud615 \uc7a1\ud78c \uc2dd\ub2e8\uc740 \uc2e0\uccb4\uc5d0 \ud544\uc218 \uc601\uc591\uc18c\ub97c \uacf5\uae09\ud558\uace0 \uc815\uc0c1\uc801\uc778 \uc2e0\uc9c4 \ub300\uc0ac\ub97c \uc720\uc9c0\ud569\ub2c8\ub2e4. \uc801\ub2f9\ud55c \uc6b4\ub3d9\uc740 \uc2ec\ud3d0 \uae30\ub2a5\uc744 \uac15\ud654\ud558\uace0 \uba74\uc5ed\ub825\uacfc \uc2e0\uc9c4\ub300\uc0ac \uc218\uc900\uc744 \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. NMN\uacfc \uc774\ub7ec\ud55c \uc0dd\ud65c \uc2b5\uad00 \uc694\uc18c\ub97c \uc720\uae30\uc801\uc73c\ub85c \uacb0\ud569\ud574\uc57c\ub9cc \uc885\ud569\uc801\uc778 \ud56d\ub178\ud654 \ud6a8\uacfc\ub97c \uadf9\ub300\ud654\ud560 \uc218 \uc788\uc73c\uba70, NMN\uc774 \uac00\uc838\ub2e4\uc8fc\ub294 \uac74\uac15\uc0c1\uc758 \uc774\uc810\uc744 \ub204\ub9ac\uba74\uc11c \uc88b\uc740 \uc0dd\ud65c \uc2b5\uad00\uc744 \uc720\uc9c0\ud558\uace0, \uc2e0\uccb4 \uac74\uac15\uc744 \uc99d\uc9c4\ud558\uba70 \ub178\ud654\ub97c \uc9c0\uc5f0\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uacfc\ud559\uc801 \ud56d\ub178\ud654\uc758 \uc0c8\ub85c\uc6b4 \uae30\ud68c\ub97c \ud569\ub9ac\uc801\uc73c\ub85c \uc218\uc6a9\ud558\uc138\uc694\"\"<\/h2>\n

NMN\uc758 \ubd80\uc0c1\uc740 \uc774\ub860\uc801 \ud0d0\uad6c\uc5d0\uc11c \uc784\uc0c1 \uc801\uc6a9\uc73c\ub85c \ub098\uc544\uac00\ub294 \ud56d\ub178\ud654 \uc5f0\uad6c\uc758 \uc911\uc694\ud55c \uc9c4\uc804\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. NMN\uc758 \uac00\uce58\ub294 \uc138\ud3ec \uc218\uc900\uc5d0\uc11c\uc758 \ud68d\uae30\uc801\uc778 \ubc1c\uc804\ubfd0\ub9cc \uc544\ub2c8\ub77c, \uc0c1\uc6a9\ud654 \uacfc\uc815\uc5d0\uc11c\uc758 \uaddc\uc81c\uc801 \uc5b4\ub824\uc6c0\uc5d0\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \uc18c\ube44\uc790\ub294 \uacfc\ud559\uc801 \uadfc\uac70\ub97c \ubc14\ud0d5\uc73c\ub85c \ud569\ub9ac\uc801\uc778 \uc120\ud0dd\uc744 \ud574\uc57c \ud558\uba70, \uaddc\uc815\uc744 \uc900\uc218\ud558\ub294 \uc720\ud1b5 \ucc44\ub110\uc744 \ud1b5\ud574 \uacf5\uae09\ub418\ub294 \uace0\uc21c\ub3c4 \uc81c\ud488\uc5d0 \uc9d1\uc911\ud558\uace0, \uac1c\uc778 \ub9de\ucda4\ud615 \uac74\uac15 \uad00\ub9ac \uacc4\ud68d\uc5d0 NMN\uc744 \ud3ec\ud568\uc2dc\ucf1c\uc57c \ud569\ub2c8\ub2e4. \uae30\uc220 \ubc1c\uc804\uacfc \uaddc\uc81c \uac1c\uc120\uc744 \ud1b5\ud574 NMN\uc740 \uc815\ubc00 \ud56d\ub178\ud654 \ubd84\uc57c\uc758 \ud575\uc2ec \ub3c4\uad6c\uac00 \ub418\uc5b4 \uc778\uac04\uc758 \uac74\uac15\ud55c \uc218\uba85\uc744 \uc9c0\uc18d\uc801\uc73c\ub85c \uc5f0\uc7a5\ud558\ub294 \ub370 \uae30\uc5ec\ud560 \uac83\uc73c\ub85c \uae30\ub300\ub429\ub2c8\ub2e4.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

NMN \ub610\ub294 \u03b2-\ub2c8\ucf54\ud2f4\uc544\ubbf8\ub4dc \ubaa8\ub178\ub274\ud074\ub808\uc624\ud0c0\uc774\ub4dc\ub294 NAD+\uc758 \uc9c1\uc811\uc801\uc778 \uc804\uad6c\uccb4\uc774\uba70 \uc778\uccb4\uc5d0\uc11c \uc790\uc5f0\uc801\uc73c\ub85c \uc0dd\uc131\ub418\ub294 \uc0dd\ub9ac\ud65c\uc131 \ub274\ud074\ub808\uc624\ud0c0\uc774\ub4dc\uc785\ub2c8\ub2e4. \ubd84\uc790 \uad6c\uc870\ub294 \ub2c8\ucf54\ud2f4\uc544\ubbf8\ub4dc\uae30, \ub9ac\ubcf4\uc2a4\ub2f9, \uadf8\ub9ac\uace0 \uc778\uc0b0\uae30\ub85c \uad6c\uc131\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4. \u03b2-\uc774\uc131\uc9c8\uccb4\ub9cc\uc774 \uc0dd\ubb3c\ud559\uc801 \ud65c\uc131\uc744 \uac16\uc2b5\ub2c8\ub2e4. \ubb3c\uc5d0 \uc798 \ub179\uace0 \uc57d\uc0b0\uc131(pH 3-4)\uc774\ubbc0\ub85c \ud65c\uc131\uc744 \uc720\uc9c0\ud558\ub824\uba74 \ube5b\uacfc \ubb3c\uc744 \ud53c\ud574 \ubcf4\uad00\ud574\uc57c \ud569\ub2c8\ub2e4. NMN\uc740 \uc544\ubcf4\uce74\ub3c4\ub098 \uc5d0\ub2e4\ub9c8\uba54\uc640 \uac19\uc740 \uacfc\uc77c\uacfc \ucc44\uc18c\uc5d0 \ud48d\ubd80\ud558\uac8c \ud568\uc720\ub418\uc5b4 \uc788\uc73c\uba70, \uc778\uccb4\uc5d0\uc11c\ub3c4 \ud569\uc131\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ub178\ud654\uac00 \uc9c4\ud589\ub428\uc5d0 \ub530\ub77c \uc2e0\uccb4\uc758 NMN … Continue reading NMN: \ubd84\uc790 \uba54\ucee4\ub2c8\uc998\ubd80\ud130 \ud56d\ub178\ud654 \uc2e4\ucc9c\uae4c\uc9c0 \uacfc\ud559\uc801 \ubd84\uc11d<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":2816,"parent":0,"menu_order":34,"comment_status":"open","ping_status":"open","template":"","format":"standard","meta":{"footnotes":""},"class_list":["post-2815","blog","type-blog","status-publish","format-standard","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog\/2815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog"}],"about":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/types\/blog"}],"author":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/comments?post=2815"}],"version-history":[{"count":0,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog\/2815\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/media\/2816"}],"wp:attachment":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/media?parent=2815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}