{"id":2823,"date":"2025-10-16T02:36:30","date_gmt":"2025-10-16T02:36:30","guid":{"rendered":"https:\/\/www.focusherb.com\/kr\/?post_type=blog&p=2823"},"modified":"2025-10-16T02:36:30","modified_gmt":"2025-10-16T02:36:30","slug":"%ec%a0%9c%eb%8b%88%ec%8a%a4%ed%85%8c%ec%9d%b8%ef%bc%9a%eb%8b%a4%ec%9e%ac%eb%8b%a4%eb%8a%a5%ed%95%9c-%ec%8b%9d%eb%ac%bc%ec%84%b1-%ec%97%90%ec%8a%a4%ed%8a%b8%eb%a1%9c%ea%b2%90%ea%b3%bc-%ea%b7%b8","status":"publish","type":"blog","link":"https:\/\/www.focusherb.com\/kr\/blog\/%ec%a0%9c%eb%8b%88%ec%8a%a4%ed%85%8c%ec%9d%b8%ef%bc%9a%eb%8b%a4%ec%9e%ac%eb%8b%a4%eb%8a%a5%ed%95%9c-%ec%8b%9d%eb%ac%bc%ec%84%b1-%ec%97%90%ec%8a%a4%ed%8a%b8%eb%a1%9c%ea%b2%90%ea%b3%bc-%ea%b7%b8\/","title":{"rendered":"\uc81c\ub2c8\uc2a4\ud14c\uc778\uff1a\ub2e4\uc7ac\ub2e4\ub2a5\ud55c \uc2dd\ubb3c\uc131 \uc5d0\uc2a4\ud2b8\ub85c\uac90\uacfc \uadf8 \uac74\uac15 \uc7a0\uc7ac\ub825"},"content":{"rendered":"

\uc81c\ub2c8\uc2a4\ud14c\uc778 \ud654\ud559\uc801\uc73c\ub85c 5,7-\ub514\ud558\uc774\ub4dc\ub85d\uc2dc-3-(4-\ud558\uc774\ub4dc\ub85d\uc2dc\ud398\ub2d0)-4H-1-\ubca4\uc870\ud53c\ub780-4-\uc628\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc73c\uba70, \ubd84\uc790\uc2dd\uc740 C\u2081\u2085H\u2081\u2080O\u2085\uc774\uace0 \ubd84\uc790\ub7c9\uc740 270.24\uc785\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \ubd84\uc790 \uad6c\uc870\ub294 \uc774\uc18c\ud50c\ub77c\ubcf4\ub178\uc774\ub4dc \uacc4\uc5f4 \ud654\ud569\ubb3c\uacfc \uc77c\uce58\ud558\uba70, \ud398\ub180\uc131 \uc218\uc0b0\uae30, \ud53c\ub860 \uace0\ub9ac, \ubca4\uc820 \uace0\ub9ac\ub85c \uad6c\uc131\ub41c \ub3c5\ud2b9\ud55c \ud654\ud559 \uad6c\uc870\ub97c \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uad6c\uc870\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \ud3f4\ub9ac\ud398\ub180\uc758 \uc804\ud615\uc801\uc778 \ub2e4\uc591\ud55c \ud654\ud559\uc801 \ud2b9\uc131\uc744 \ubd80\uc5ec\ud558\uc5ec \ud56d\uc0b0\ud654 \ud65c\uc131\uc744 \ub098\ud0c0\ub0bc \uc218 \uc788\ub3c4\ub85d \ud569\ub2c8\ub2e4. \uc218\uc18c \uc6d0\uc790\ub098 \uc804\uc790\ub97c \uc81c\uacf5\ud568\uc73c\ub85c\uc368, \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc288\ud37c\uc625\uc0ac\uc774\ub4dc \uc74c\uc774\uc628 \ub77c\ub514\uce7c\uacfc \ud558\uc774\ub4dc\ub85d\uc2e4 \ub77c\ub514\uce7c\uacfc \uac19\uc740 \uccb4\ub0b4 \uc790\uc720 \ub77c\ub514\uce7c\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uc81c\uac70\ud558\uc5ec \uc138\ud3ec\uc640 \uc870\uc9c1\uc758 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \uc190\uc0c1\uc744 \uc904\uc774\uace0 \uc2e0\uccb4\uc758 \uc0b0\ud654\ud658\uc6d0 \uade0\ud615\uc744 \uc720\uc9c0\ud558\ub294 \ub370 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \ub610\ud55c, \uc5d0\uc2a4\ud2b8\ub85c\uac90\uacfc \uad6c\uc870\uc801\uc73c\ub85c \uc720\uc0ac\ud558\uc5ec \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uc6a9\uccb4(ER\u03b1\/ER\u03b2)\uc5d0 \uacb0\ud569\ud558\uc5ec \uc591\ubc29\ud5a5 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc870\uc808 \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uce58\uac00 \ub0ae\uc744 \ub54c\ub294 \uc5d0\uc2a4\ud2b8\ub85c\uac90\uc758 \ud6a8\uacfc\ub97c \ubaa8\ubc29\ud558\uc5ec \uc218\uc6a9\uccb4\uc5d0 \uacb0\ud569\ud558\uc5ec \uc57d\ud55c \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc720\uc0ac \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uce58\uac00 \ub192\uc744 \ub54c\ub294 \uc218\uc6a9\uccb4\uc5d0 \uacbd\uc7c1\uc801\uc73c\ub85c \uacb0\ud569\ud558\uc5ec \uc5d0\uc2a4\ud2b8\ub85c\uac90\uc758 \ud6a8\uacfc\ub97c \ucc28\ub2e8\ud568\uc73c\ub85c\uc368 \uccb4\ub0b4 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uce58\ub97c \ube44\uad50\uc801 \uc548\uc815\uc801\uc73c\ub85c \uc720\uc9c0\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ub3c5\ud2b9\ud55c \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc870\uc808 \ud2b9\uc131\uc740 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uad00\ub828 \uc0dd\ub9ac\uc801 \ubc0f \ubcd1\ub9ac\uc801 \uacfc\uc815\uc5d0 \uc7a0\uc7ac\uc801\uc73c\ub85c \uc801\uc6a9\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\"\"<\/p>\n

\ucc9c\uc5f0 \uc790\uc6d0 \ubc0f \uc81c\uc870 \uacbd\ub85c<\/h2>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778<\/strong><\/a> \uc8fc\ub85c \ub300\ub450\uc640 \uadf8 \uac00\uacf5\ud488\uc5d0\uc11c \ubc1c\uacac\ub418\uba70 \ub300\ub450 \uc774\uc18c\ud50c\ub77c\ubcf8\uc758 \uc8fc\uc694 \ud65c\uc131 \uc778\uc790\uc785\ub2c8\ub2e4. \ub300\ub450 \uc0dd\uc7a5 \uacfc\uc815\uc5d0\uc11c \ub2e4\uc591\ud55c \uc774\uc18c\ud50c\ub77c\ubcf8\uc774 \uc0dd\uc131\ub418\uba70, \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc8fc\ub85c \ub300\ub450\uc5d0\uc11c \ubc30\ub2f9\uccb4(\uc81c\ub2c8\uc2a4\ud2f4)\ub85c \uc874\uc7ac\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud615\ud0dc\uc758 \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc7a5\ub0b4 \uc7a5\ub0b4 \uc138\uade0\ucd1d\uc5d0 \uc758\ud574 \uc720\ub9ac \uc544\uae00\ub9ac\ucf58\uc73c\ub85c \uac00\uc218\ubd84\ud574\ub418\uc5b4 \uccb4\ub0b4\uc5d0 \ud761\uc218\ub418\uace0 \ud65c\uc6a9\ub429\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uc6b0\ub9ac\uac00 \ub300\ub450 \uac00\uacf5\ud488\uc744 \uc12d\ucde8\ud558\uba74 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uc774 \uc81c\ub2c8\uc2a4\ud2f4\uc744 \ubd84\ud574\ud558\uc5ec \uc720\ub9ac \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \ubc29\ucd9c\ud558\uace0, \uc774 \uc720\ub9ac \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc0dd\ub9ac \ud65c\uc131\uc744 \ubc1c\ud718\ud569\ub2c8\ub2e4.<\/p>\n

\uc0b0\uc5c5 \uc0dd\uc0b0\uc5d0\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \uc81c\uc870\ud558\ub294 \uc8fc\uc694 \ubc29\ubc95\uc740 \uc2dd\ubb3c \ucd94\ucd9c\uacfc \ud654\ud559 \ud569\uc131\uc785\ub2c8\ub2e4. \uc2dd\ubb3c \ucd94\ucd9c\ubc95\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \ub300\ub450\ubc15\uc744 \uc6d0\ub8cc\ub85c \uc0ac\uc6a9\ud569\ub2c8\ub2e4. \uc774\ub294 \ub300\ub450 \uac00\uacf5 \ud6c4 \uc794\ub958\ubb3c\uc778 \ub300\ub450\ubc15\uc5d0\ub3c4 \uc77c\uc815\ub7c9\uc758 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \ud568\uc720\ub418\uc5b4 \uc788\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \uc801\uc808\ud55c \uc6a9\ub9e4\ub97c \uc774\uc6a9\ud55c \ucd94\ucd9c \ubc0f \uace0\uc131\ub2a5 \uc561\uccb4 \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c\uc640 \uac19\uc740 \uae30\uc220\uc744 \uc774\uc6a9\ud55c \uc815\uc81c \ub4f1 \uc77c\ub828\uc758 \ubcf5\uc7a1\ud55c \ucd94\ucd9c \uacf5\uc815\uc744 \ud1b5\ud574 \uace0\uc21c\ub3c4 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \uc5bb\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \ubc29\ubc95\uc740 \ucc9c\uc5f0\uc801\uc774\uace0 \uc548\uc804\ud55c \uc81c\ud488\uc774\ub77c\ub294 \uc7a5\uc810\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ucd94\ucd9c \uacf5\uc815\uc740 \ube44\uad50\uc801 \ubcf5\uc7a1\ud558\uace0 \ube44\uc6a9\uc774 \ub9ce\uc774 \ub4e4\uba70, \uc6d0\ub8cc\uc758 \uac00\uc6a9\uc131\uc5d0 \ub530\ub77c \uc218\uc728\uc774 \uc81c\ud55c\ub429\ub2c8\ub2e4. \ud654\ud559 \ud569\uc131\uc740 \ud50c\ub77c\ubcf4\ub178\uc774\ub4dc \uace8\uaca9\uc744 \uad6c\ucd95\ud558\uc5ec \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \uc0dd\uc0b0\ud558\ub294 \ud654\ud559 \ud569\uc131 \uae30\uc220\uc744 \ud65c\uc6a9\ud569\ub2c8\ub2e4. \uc774 \ubc29\ubc95\uc740 \ubc18\uc751 \uc870\uac74\uc744 \uc815\ubc00\ud558\uac8c \uc81c\uc5b4\ud558\uc5ec \ub300\ub7c9 \uc0dd\uc0b0\uc774 \uac00\ub2a5\ud558\uba70 \uc99d\uac00\ud558\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc2dc\uc7a5 \uc218\uc694\ub97c \ucda9\uc871\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ud654\ud559 \ud569\uc131 \uacf5\uc815\uc740 \ubcf5\uc7a1\ud55c \ud654\ud559 \ubc18\uc751\uacfc \uc5ec\ub7ec \ud654\ud559 \uc2dc\uc57d\uc758 \uc0ac\uc6a9\uc744 \uc218\ubc18\ud560 \uc218 \uc788\uc73c\ubbc0\ub85c \uc81c\ud488\uc758 \uc21c\ub3c4\uc640 \uc548\uc804\uc131\uc5d0 \ub300\ud55c \uc5c4\uaca9\ud55c \uad00\ub9ac\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \ud604\uc7ac \uace0\uc21c\ub3c4(\u226598%) \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc81c\ud488\uc740 \uae30\ub2a5\uc131 \uc2dd\ud488 \ubc0f \uc758\uc57d\ud488\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\uc5b4 \uacf5\uc911 \ubcf4\uac74 \ubc0f \uad00\ub828 \uc9c8\ubcd1\uc758 \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \ud070 \ub3c4\uc6c0\uc744 \uc8fc\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud575\uc2ec \uc0dd\ubb3c\ud559\uc801 \ud65c\uc131 \ubc0f \uac74\uac15 \ud6a8\uacfc<\/h2>\n

\"\"<\/p>\n

(I) \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc870\uc808 \ubc0f \uc0dd\ub9ac \uae30\ub2a5<\/h3>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778 \ub3c5\ud2b9\ud55c \ubd84\uc790 \uad6c\uc870\ub85c \uc778\ud574 \uc778\uccb4\uc758 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uc6a9\uccb4\uc5d0 \uacb0\ud569\ud558\uc5ec \uc5d0\uc2a4\ud2b8\ub85c\uac90\uc744 \ubaa8\ubc29\ud558\uac70\ub098 \uae38\ud56d\ud558\uc5ec \uc778\uccb4 \ub0b4\ubd84\ube44\uacc4 \uc870\uc808\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4.<\/p>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778 \ud3d0\uacbd \uad00\ub9ac\uc5d0 \ud0c1\uc6d4\ud55c \ud6a8\uacfc\ub97c \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uc5ec\uc131\uc774 \ub098\uc774\uac00 \ub4e4\uba74\uc11c \ub09c\uc18c \uae30\ub2a5\uc774 \uc810\ucc28 \uac10\uc18c\ud558\uc5ec \uc5d0\uc2a4\ud2b8\ub85c\uac90 \ubd84\ube44\uac00 \ud06c\uac8c \uac10\uc18c\ud569\ub2c8\ub2e4. \uc774\ub294 \uc548\uba74\ud64d\uc870\ub098 \uc57c\uac04 \ubc1c\ud55c\uacfc \uac19\uc740 \uc77c\ub828\uc758 \ud3d0\uacbd \uc99d\uc0c1\uc744 \uc720\ubc1c\ud558\uc5ec \uc5ec\uc131\uc758 \uc0b6\uc758 \uc9c8\uc5d0 \uc2ec\uac01\ud55c \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uc6a9\uccb4 \ubc1c\ud604\uc744 \uc870\uc808\ud558\uc5ec \uc2dc\uc0c1\ud558\ubd80 \uccb4\uc628 \uc870\uc808 \uc911\ucd94\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc784\uc0c1 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \ud48d\ubd80\ud55c \uc74c\uc2dd\uc774\ub098 \ubcf4\ucda9\uc81c\ub97c \uc12d\ucde8\ud558\uba74 \ub9ce\uc740 \uc5ec\uc131\uc758 \uc548\uba74\ud64d\uc870\uc640 \uc57c\uac04 \ubc1c\ud55c\uc774 \ud06c\uac8c \uc644\ud654\ub418\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ud3d0\uacbd \uc5ec\uc131\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c \ud55c \uc5f0\uad6c\uc5d0\uc11c\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778 \ubcf4\ucda9\uc81c\ub97c 12\uc8fc \ub3d9\uc548 \uc9c0\uc18d\uc801\uc73c\ub85c \uc12d\ucde8\ud55c \ud6c4 \uc548\uba74\ud64d\uc870\uc758 \ube48\ub3c4\uc640 \uc2ec\uac01\ub3c4\uac00 \ud604\uc800\ud788 \uac10\uc18c\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \ud608\uc911 \uc9c0\uc9c8 \uc218\uce58\uc5d0\ub3c4 \uae0d\uc815\uc801\uc778 \uc601\ud5a5\uc744 \ubbf8\uccd0 \uc800\ubc00\ub3c4 \uc9c0\ub2e8\ubc31 \ucf5c\ub808\uc2a4\ud14c\ub864(LDL-C) \uc218\uce58\ub97c \ub0ae\ucd94\uace0 \uace0\ubc00\ub3c4 \uc9c0\ub2e8\ubc31 \ucf5c\ub808\uc2a4\ud14c\ub864(HDL-C) \uc218\uce58\ub97c \uc99d\uac00\uc2dc\ucf1c \uc2ec\ud608\uad00 \uc9c8\ud658 \uc704\ud5d8\uc744 \uc904\uc774\uace0 \ud3d0\uacbd\uae30 \uc5ec\uc131\uc758 \uac74\uac15\uc744 \ubcf4\ud638\ud558\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc90d\ub2c8\ub2e4.<\/p>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778 \ubf08 \uac74\uac15\uc5d0\ub3c4 \uc911\uc694\ud569\ub2c8\ub2e4. \ud3d0\uacbd\uae30 \uc5ec\uc131\uc758 \uacbd\uc6b0, \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uce58\uac00 \uae09\uaca9\ud788 \uac10\uc18c\ud558\uba74 \ud30c\uace8\uc138\ud3ec \ud65c\ub3d9\uc774 \uc99d\uac00\ud558\uace0 \uc870\uace8\uc138\ud3ec \uae30\ub2a5\uc774 \uc5b5\uc81c\ub418\uc5b4 \uae09\uaca9\ud55c \uace8 \uc190\uc2e4\uacfc \uace8\ub2e4\uacf5\uc99d \uc704\ud5d8\uc774 \ud06c\uac8c \uc99d\uac00\ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \ud30c\uace8\uc138\ud3ec \ud65c\ub3d9\uc744 \uc5b5\uc81c\ud558\uc5ec \uace8 \uc870\uc9c1\uc758 \uc7ac\ud761\uc218 \ubc0f \ud30c\uad34\ub97c \uc904\uc785\ub2c8\ub2e4. \ub610\ud55c \uc870\uace8\uc138\ud3ec\uc758 \ubd84\ud654 \ubc0f \uc99d\uc2dd\uc744 \ucd09\uc9c4\ud558\uc5ec \uc870\uace8\uc138\ud3ec \uae30\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \uc0c8\ub85c\uc6b4 \ubf08 \ud615\uc131\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \ud568\uc720\ub41c \uc2dd\ud488\uc774\ub098 \ubcf4\ucda9\uc81c\ub97c \uc7a5\uae30\uac04 \uc12d\ucde8\ud558\uba74 \ud3d0\uacbd\uae30 \uc5ec\uc131\uc758 \uace8\ubc00\ub3c4\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \uac1c\uc120\ud560 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ub784\ub85d\uc2dc\ud39c\uacfc \uac19\uc740 \uc120\ud0dd\uc801 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uc6a9\uccb4 \uc870\uc808\uc81c(SERM)\uc640 \ube44\uad50\ud588\uc744 \ub54c, \uc81c\ub2c8\uc2a4\ud14c\uc778 \uace8\ubc00\ub3c4 \uac1c\uc120 \ud6a8\uacfc\uac00 \ube44\uc2b7\ud558\uc9c0\ub9cc, \ucc9c\uc5f0 \uc131\ubd84\uc774\uba70 \ubd80\uc791\uc6a9\uc774 \uc0c1\ub300\uc801\uc73c\ub85c \uc801\ub2e4\ub294 \uc7a5\uc810\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ud3d0\uacbd \ud6c4 \uc5ec\uc131\uc758 \uace8\ub2e4\uacf5\uc99d \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \uc548\uc804\ud558\uace0 \ud6a8\uacfc\uc801\uc778 \ub300\uc548\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n

(II) \uc9c8\ubcd1 \uc608\ubc29 \ubc0f \uce58\ub8cc \uac00\ub2a5\uc131<\/h3>\n

1. \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658 \uc911\uc7ac<\/h4>\n

\ud3f4\ub780\ub4dc \uadf8\ub2e8\uc2a4\ud06c \ub300\ud559\uad50\uc758 \uc5f0\uad6c\ub294 \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658 \uc911\uc7ac, \ud2b9\ud788 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \uce58\ub8cc\uc5d0 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \uc5ed\ud560\uc5d0 \ub300\ud55c \uac15\ub825\ud55c \uc99d\uac70\ub97c \uc81c\uc2dc\ud588\uc2b5\ub2c8\ub2e4. \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc740 \ub1cc\uc5d0 \uc544\ubc00\ub85c\uc774\ub4dc \ubca0\ud0c0 \ub2e8\ubc31\uc9c8(A\u03b2)\uc774 \ube44\uc815\uc0c1\uc801\uc73c\ub85c \ucd95\uc801\ub418\uace0 \uc2e0\uacbd \uc5fc\uc99d\uacfc \uc2e0\uacbd \uc138\ud3ec \uc0ac\uba78\uc774 \ub098\ud0c0\ub098\ub294 \ud754\ud55c \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658\uc73c\ub85c, \uc810\uc9c4\uc801\uc778 \uc778\uc9c0 \uc7a5\uc560\uc640 \uae30\uc5b5 \uc0c1\uc2e4\uc744 \ucd08\ub798\ud569\ub2c8\ub2e4.<\/p>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778 \ub2e4\uc591\ud55c \uae30\uc804\uc744 \ud1b5\ud574 \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc758 \ubcd1\ub9ac\ud559\uc801 \uc9c4\ud589\uc744 \uc644\ud654\ud569\ub2c8\ub2e4. \uccab\uc9f8, \uc544\ubc00\ub85c\uc774\ub4dc \uc804\uad6c\uccb4 \ub2e8\ubc31\uc9c8(APP)\uc744 \ubd84\ud574\ud558\uc5ec A\u03b2\ub97c \uc0dd\uc131\ud558\ub294 \ud575\uc2ec \ud6a8\uc18c\uc778 \u03b2-\uc138\ud06c\ub808\ud0c0\uc81c\ub97c \uc5b5\uc81c\ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \u03b2-\uc138\ud06c\ub808\ud0c0\uc81c \uc5b5\uc81c \ud6a8\uacfc\ub294 A\u03b2 \uc0dd\uc131\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uac10\uc18c\uc2dc\ucf1c \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc758 \uc9c4\ud589\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4. \ub458\uc9f8, \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc9c0\uc9c8 \ub300\uc0ac \ubc0f \uc5fc\uc99d \uc870\uc808\uc744 \ud3ec\ud568\ud55c \uc2e0\uccb4\uc758 \ub2e4\uc591\ud55c \uc0dd\ub9ac \uacfc\uc815\uc5d0 \uad00\uc5ec\ud558\ub294 \ud575 \uc218\uc6a9\uccb4\uc778 \ud37c\uc625\uc2dc\uc880 \uc99d\uc2dd\uccb4 \ud65c\uc131\ud654 \uc218\uc6a9\uccb4 \u03b3(PPAR\u03b3)\ub97c \ud65c\uc131\ud654\ud569\ub2c8\ub2e4. PPAR\u03b3\uc758 \ud65c\uc131\ud654\ub294 \ub1cc\uc5d0\uc11c \uc911\uc694\ud55c \uc2e0\uacbd \ubcf4\ud638 \uc5ed\ud560\uc744 \ud558\ub294 \uc544\ud3f4\ub9ac\ud3ec\ub2e8\ubc31\uc9c8 E(ApoE)\uc758 \ubc1c\ud604\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4. ApoE\ub294 A\u03b2\uc5d0 \uacb0\ud569\ud558\uc5ec A\u03b2\uc758 \uc81c\uac70 \ubc0f \ub300\uc0ac\ub97c \ucd09\uc9c4\ud558\uace0, \ub1cc \ub0b4 \ucd95\uc801\uc744 \uac10\uc18c\uc2dc\ucf1c \uc2e0\uacbd \uc138\ud3ec\uc5d0 \ub300\ud55c \ub3c5\uc131 \ud6a8\uacfc\ub97c \uc644\ud654\ud569\ub2c8\ub2e4.<\/p>\n

\ub354 \ub098\uc544\uac00, \ucd5c\uadfc \uc5f0\uad6c\uc5d0\uc11c\ub294 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70\uacfc \ub1cc \uac74\uac15, \uc989 \uc7a5-\ub1cc \ucd95(gut-brain axis) \uc0ac\uc774\uc758 \ubc00\uc811\ud55c \uc5f0\uad00\uc131\uc774 \ubc1d\ud600\uc84c\uc2b5\ub2c8\ub2e4. \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ud658\uc790\ub294 \uc885\uc885 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c \ubd88\uade0\ud615\uc744 \uacbd\ud5d8\ud558\uba70, \uc774\ub294 \uc2e0\uacbd \uc5fc\uc99d\uacfc \uc9c8\ubcd1 \uc9c4\ud589\uc744 \ub354\uc6b1 \uc545\ud654\uc2dc\ud0b5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70\uc744 \uc870\uc808\ud558\ub294 \ub2a5\ub825\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70\uc744 \uc7ac\uade0\ud615\ud654\ud558\uace0, \uc7a5-\ub1cc \ucd95\uc744 \ud68c\ubcf5\ud558\uace0, \uc2e0\uacbd \uc5fc\uc99d \ubc18\uc751\uc744 \uac10\uc18c\uc2dc\ud0a4\uace0, \uc2e0\uacbd \uc138\ud3ec\uc5d0 \ub354 \uac74\uac15\ud55c \ubbf8\uc138\ud658\uacbd\uc744 \uc81c\uacf5\ud558\uc5ec \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ud658\uc790\uc758 \uc778\uc9c0 \uae30\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uacb0\uacfc\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \uce58\ub8cc\ub97c \uc704\ud55c \uc2e0\uc57d \ub610\ub294 \ubcf4\uc870 \uc694\ubc95\uc73c\ub85c \ud65c\uc6a9\ub420 \uac00\ub2a5\uc131\uc774 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud558\uba70, \ub9ce\uc740 \ud658\uc790\uc5d0\uac8c \uc0c8\ub85c\uc6b4 \ud76c\ub9dd\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n

2. \uc885\uc591 \uc5b5\uc81c \ud6a8\uacfc<\/h4>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778 \uc8fc\ub85c \ud2f0\ub85c\uc2e0 \ud0a4\ub098\uc81c \uc5b5\uc81c\uc81c \uc5ed\ud560\uc744 \ud1b5\ud574 \uc885\uc591 \uc5b5\uc81c\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \ud2f0\ub85c\uc2e0 \ud0a4\ub098\uc81c\ub294 \uc138\ud3ec \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc5d0\uc11c \ud575\uc2ec\uc801\uc778 \uc5ed\ud560\uc744 \ud558\uba70, \uc138\ud3ec \uc99d\uc2dd, \ubd84\ud654, \uc774\ub3d9, \uc0dd\uc874\uacfc \uac19\uc740 \uc911\uc694\ud55c \uc0dd\ub9ac\uc801 \uacfc\uc815\uc744 \uc870\uc808\ud569\ub2c8\ub2e4. \uc885\uc591 \uc138\ud3ec\uc5d0\uc11c \ud2f0\ub85c\uc2e0 \ud0a4\ub098\uc81c \ud65c\uc131\uc740 \uc885\uc885 \ube44\uc815\uc0c1\uc801\uc73c\ub85c \uc99d\uac00\ud558\uc5ec \ud1b5\uc81c\ub418\uc9c0 \uc54a\ub294 \uc99d\uc2dd\uacfc \uc804\uc774\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4.<\/p>\n

\uc0c1\ud53c\uc138\ud3ec \uc131\uc7a5\uc778\uc790 \uc218\uc6a9\uccb4(EGFR) \uc2e0\ud638\uc804\ub2ec \uacbd\ub85c\ub294 \uc885\uc591 \ubc1c\uc0dd \ubc0f \uc9c4\ud589\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. EGFR\uc774 \ud574\ub2f9 \ub9ac\uac04\ub4dc\uc640 \uacb0\ud569\ud558\uba74 \ud65c\uc131\ud654\ub429\ub2c8\ub2e4 \uc77c\ub828\uc758 \ud558\ub958 \uc2e0\ud638\uc804\ub2ec \ubd84\uc790\ub294 \uc885\uc591 \uc138\ud3ec\uc758 \uc99d\uc2dd\uacfc \uc774\ub3d9\uc744 \ucd09\uc9c4\ud558\uace0 \ud608\uad00\uc2e0\uc0dd\uc744 \uc720\ub3c4\ud558\uc5ec \uc885\uc591 \uc131\uc7a5 \ubc0f \uc804\uc774\uc5d0 \ud544\uc218\uc801\uc778 \uc601\uc591\uc18c\uc640 \uc0b0\uc18c\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 EGFR \uc2e0\ud638\uc804\ub2ec \uacbd\ub85c\ub97c \ud2b9\uc774\uc801\uc73c\ub85c \ucc28\ub2e8\ud558\uc5ec \ud2f0\ub85c\uc2e0 \ud0a4\ub098\uc544\uc81c \ud65c\uc131\uc744 \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc885\uc591 \uc138\ud3ec\uc758 \uc99d\uc2dd \ubc0f \uc0dd\uc874 \uc2e0\ud638\ub97c \ucc28\ub2e8\ud558\uace0 \uc885\uc591 \uc138\ud3ec\uc758 \uc99d\uc2dd\uacfc \ud608\uad00\uc2e0\uc0dd\uc744 \uc5b5\uc81c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uad11\ubc94\uc704\ud55c \uc804\uc784\uc0c1 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \ub2e4\uc591\ud55c \uc885\uc591 \uc138\ud3ec \uc720\ud615, \ud2b9\ud788 \uc720\ubc29\uc554 \ubc0f \uc804\ub9bd\uc120\uc554\uacfc \uac19\uc740 \ud638\ub974\ubaac \uc758\uc874\uc131 \uc554\uc5d0 \uc720\uc758\ubbf8\ud55c \uc5b5\uc81c \ud6a8\uacfc\ub97c \ubcf4\uc600\uc73c\uba70, \uc774\ub294 \uc608\ubc29\uc5d0 \uc0c1\ub2f9\ud55c \uc7a0\uc7ac\ub825\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4. \uc720\ubc29\uc554 \uc138\ud3ec\uc8fc \uc5f0\uad6c\uc5d0\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778 G1 \ub610\ub294 G2\/M \ub2e8\uacc4\uc5d0\uc11c \uc138\ud3ec\uc8fc\uae30 \uc815\uc9c0\ub97c \uc720\ub3c4\ud558\uc5ec \uc554\uc138\ud3ec\uac00 \uc138\ud3ec \ubd84\uc5f4\uae30\ub85c \uc9c4\uc785\ud558\ub294 \uac83\uc744 \ubc29\uc9c0\ud558\uace0 \uc99d\uc2dd\uc744 \uc5b5\uc81c\ud560 \uc218 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4. \ub610\ud55c \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc138\ud3ec\uc790\uba78\uc0ac\ub97c \uc720\ub3c4\ud558\uc5ec \uc138\ud3ec \ub0b4 \uc138\ud3ec\uc790\uba78\uc0ac \uc2e0\ud638\uc804\ub2ec \uacbd\ub85c\ub97c \ud65c\uc131\ud654\ud558\uace0 \uc554\uc138\ud3ec\uc758 \uc790\uae30\ud30c\uad34 \ud504\ub85c\uadf8\ub7a8\uc744 \uc2dc\uc791\ud558\ub3c4\ub85d \uc720\ub3c4\ud558\uc5ec \uc554\uc138\ud3ec\uc758 \uc218\ub97c \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub3d9\ubb3c \uc5f0\uad6c\uc5d0\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \ud48d\ubd80\ud55c \uc2dd\uc774 \ub610\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc9c1\uc811 \uc8fc\uc0ac\ub294 \uc720\ubc29\uc554 \ubc0f \uc804\ub9bd\uc120\uc554 \uc885\uc591 \uc131\uc7a5\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uc5b5\uc81c\ud558\uace0 \uc885\uc591 \ubc1c\uc0dd\ub960\uacfc \uc804\uc774\ub97c \uac10\uc18c\uc2dc\ucf30\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uacb0\uacfc\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \uc554 \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \uc801\uc6a9\ud558\ub294 \ub370 \uc788\uc5b4 \ud0c4\ud0c4\ud55c \uc774\ub860\uc801 \ubc0f \uc2e4\ud5d8\uc801 \uadfc\uac70\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \ud604\uc7ac \uc804\uc784\uc0c1 \uc5f0\uad6c \ub2e8\uacc4\uc5d0 \uc788\uc9c0\ub9cc, \uad11\ubc94\uc704\ud55c \uc801\uc6a9 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.<\/p>\n

3. \uc2ec\ud608\uad00 \ubcf4\ud638 \uae30\uc804<\/h4>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778 \ud56d\uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\uc640 \ud56d\uc5fc\uc99d \ud6a8\uacfc\ub77c\ub294 \ub450 \uac00\uc9c0 \uc8fc\uc694 \uae30\uc804\uc744 \ud1b5\ud574 \uc0c1\ub2f9\ud55c \uc2ec\ud608\uad00 \ubcf4\ud638 \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \uc815\uc0c1\uc801\uc778 \uc0dd\ub9ac \uc870\uac74\uc5d0\uc11c\ub294 \uc2e0\uccb4\uc758 \uc0b0\ud654 \ubc0f \ud56d\uc0b0\ud654 \uc2dc\uc2a4\ud15c\uc774 \uc5ed\ub3d9\uc801\uc778 \uade0\ud615\uc744 \uc720\uc9c0\ud569\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uace0\uc9c0\ud608\uc99d, \uace0\ud608\ub2f9, \ud761\uc5f0, \ud658\uacbd \uc624\uc5fc\uacfc \uac19\uc740 \ub2e4\uc591\ud55c \ub0b4\uc678\ubd80 \uc694\uc778\uc5d0 \uc758\ud574 \uc2e0\uccb4\uac00 \uc790\uadf9\uc744 \ubc1b\uc73c\uba74 \ub9ce\uc740 \uc591\uc758 \uc790\uc720 \ub77c\ub514\uce7c\uc774 \uc0dd\uc131\ub418\uc5b4 \uc774\ub7ec\ud55c \uade0\ud615\uc744 \uae68\ub728\ub9ac\uace0 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4. \uacfc\ub3c4\ud55c \uc790\uc720 \ub77c\ub514\uce7c\uc740 \ud608\uad00 \ub0b4\ud53c \uc138\ud3ec\ub97c \uacf5\uaca9\ud558\uc5ec \uc138\ud3ec\ub9c9 \uc9c0\uc9c8\uc758 \uacfc\uc0b0\ud654\uc640 \ub2e8\ubc31\uc9c8 \ubc0f \ud575\uc0b0 \uc190\uc0c1\uc744 \uc720\ubc1c\ud558\uc5ec \ub0b4\ud53c \uc138\ud3ec\uc758 \uc815\uc0c1\uc801\uc778 \uae30\ub2a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\uace0 \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\uc99d\uc758 \ubc1c\uc0dd\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4.<\/p>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778 \uac15\ub825\ud55c \ud56d\uc0b0\ud654 \uc791\uc6a9\uc744 \ud558\uba70, \uc288\ud37c\uc625\uc0ac\uc774\ub4dc \ub514\uc2a4\ubba4\ud0c0\uc81c(SOD)\uc640 \uac19\uc740 \ud56d\uc0b0\ud654 \ud6a8\uc18c\uc758 \ud65c\uc131\uc744 \uc99d\uc9c4\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. SOD\ub294 \uccb4\ub0b4\uc758 \uc8fc\uc694 \ud56d\uc0b0\ud654 \ud6a8\uc18c\ub85c, \uc288\ud37c\uc625\uc0ac\uc774\ub4dc \uc74c\uc774\uc628 \ub77c\ub514\uce7c\uc744 \uc0b0\uc18c\uc640 \uacfc\uc0b0\ud654\uc218\uc18c\ub85c \ubd84\ud574\ud558\uc5ec \uacfc\ub3c4\ud55c \uc790\uc720 \ub77c\ub514\uce7c\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uc81c\uac70\ud558\uace0 \ub0b4\ud53c \uc138\ud3ec\uc758 \uc0b0\ud654\uc801 \uc190\uc0c1\uc744 \uc904\uc774\uba70 \uc138\ud3ec\uc758 \uc628\uc804\uc131\uacfc \uc815\uc0c1\uc801\uc778 \uae30\ub2a5\uc744 \ubcf4\ud638\ud569\ub2c8\ub2e4.<\/p>\n

\uc5fc\uc99d\uc740 \ub610\ud55c \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\uc99d\uc758 \ubc1c\uc0dd \ubc0f \uc9c4\ud589\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \ud575\uc778\uc790 \u03baB(NF-\u03baB)\ub294 \uc5fc\uc99d \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\uc5d0\uc11c \uc911\ucd94\uc801\uc778 \uc5ed\ud560\uc744 \ud558\ub294 \uc911\uc694\ud55c \uc804\uc0ac \uc778\uc790\uc785\ub2c8\ub2e4. \uc2e0\uccb4\uac00 \uc5fc\uc99d\uc5d0 \uc758\ud574 \uc790\uadf9\uc744 \ubc1b\uc73c\uba74 NF-\u03baB\uac00 \ud65c\uc131\ud654\ub418\uc5b4 \uc138\ud3ec\ud575\uc73c\ub85c \ub4e4\uc5b4\uac00 \uc77c\ub828\uc758 \uc5fc\uc99d \uad00\ub828 \uc720\uc804\uc790\uc758 \ubc1c\ud604\uc744 \uc870\uc808\ud569\ub2c8\ub2e4. \uc774\ub85c \uc778\ud574 \uc885\uc591\uad34\uc0ac\uc778\uc790 \u03b1(TNF-\u03b1) \ubc0f \uc778\ud130\ub8e8\ud0a8-6(IL-6)\uc640 \uac19\uc740 \uc5fc\uc99d \uc778\uc790\uac00 \ub300\ub7c9\uc73c\ub85c \ubc29\ucd9c\ub418\uc5b4 \uc5fc\uc99d \ubc18\uc751\uc774 \uc720\ubc1c\ub429\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 NF-\u03baB \uacbd\ub85c\uc758 \ud65c\uc131\ud654\ub97c \uc5b5\uc81c\ud558\uace0, \uc5fc\uc99d \uc778\uc790\uc758 \ubc29\ucd9c\uc744 \uc904\uc774\uba70, C-\ubc18\uc751\uc131 \ub2e8\ubc31\uc9c8(CRP)\uacfc \uac19\uc740 \uc5fc\uc99d \ud45c\uc9c0\uc790 \uc218\uce58\ub97c \ub0ae\ucd9c \uc218 \uc788\uc2b5\ub2c8\ub2e4. CRP\ub294 \uae09\uc131\uae30 \ub2e8\ubc31\uc9c8\uc774\uba70, \uc218\uce58\uac00 \ub192\uc744\uc218\ub85d \uc2ec\ud608\uad00 \uc9c8\ud658 \uc704\ud5d8\uacfc \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc5fc\uc99d \ubc18\uc751\uc744 \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \ud608\uad00\ubcbd\uc758 \uc5fc\uc99d\uc131 \uc190\uc0c1\uc744 \uc904\uc774\uace0 \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\uc99d\uc758 \uc9c4\ud589\uc744 \ub2a6\ucda5\ub2c8\ub2e4.
\n\uad00\ub828 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc81c\ub2c8\uc2a4\ud14c\uc778 \uace0\uc9c0\ud608\uc99d\uc758 \ubcf4\uc870 \uce58\ub8cc\uc5d0\ub3c4 \uc5ed\ud560\uc744 \ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uace0\uc9c0\ud608\uc99d\uc740 \ud608\uc561 \ub0b4 \uc9c0\uc9c8 \uc218\uce58\ub97c \ube44\uc815\uc0c1\uc801\uc73c\ub85c \ub192\uac8c \uc720\uc9c0\ud558\ub294\ub370, \uc774\ub7ec\ud55c \uc9c0\uc9c8\uc740 \ud608\uad00\ubcbd\uc5d0 \uce68\ucc29\ub418\uc5b4 \ud50c\ub77c\ud06c\ub97c \ud615\uc131\ud558\uae30 \uc27d\uace0, \uc774\ub294 \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\uc99d \ubc0f \uc2ec\ud608\uad00 \uc9c8\ud658\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc9c0\uc9c8 \ub300\uc0ac\ub97c \uc870\uc808\ud558\uc5ec \ud608\uc911 \ucf5c\ub808\uc2a4\ud14c\ub864, \uc911\uc131\uc9c0\ubc29, \uc800\ubc00\ub3c4\uc9c0\ub2e8\ubc31 \ucf5c\ub808\uc2a4\ud14c\ub864 \uc218\uce58\ub97c \ub0ae\ucd94\ub294 \ub3d9\uc2dc\uc5d0 \uace0\ubc00\ub3c4\uc9c0\ub2e8\ubc31 \ucf5c\ub808\uc2a4\ud14c\ub864 \uc218\uce58\ub97c \uc99d\uac00\uc2dc\ud0a4\uace0 \uc9c0\uc9c8 \ud504\ub85c\ud30c\uc77c\uc744 \uac1c\uc120\ud558\uc5ec \uc2ec\ud608\uad00 \uc9c8\ud658 \uc704\ud5d8\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc2ec\ud608\uad00 \uc9c8\ud658\uc758 \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \uc7a0\uc7ac\uc801\uc73c\ub85c \uc720\uc6a9\ud558\uba70, \uc2ec\ud608\uad00 \uac74\uac15\uc744 \uc704\ud55c \ub2e4\uac01\uc801\uc778 \ubcf4\ud638 \uae30\ub2a5\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n

\uc801\uc6a9 \ubd84\uc57c: \uae30\ub2a5\uc131 \uc2dd\ud488\ubd80\ud130 \uc815\ubc00 \uc758\ud559\uae4c\uc9c0<\/h2>\n

\"\"<\/p>\n

(I) \uc2dd\ud488 \ubc0f \uc601\uc591 \ubcf4\ucda9\uc81c<\/h3>\n

\uae30\ub2a5\uc131 \uc2dd\ud488 \ubd84\uc57c\uc5d0\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778 \ub180\ub77c\uc6b4 \uac74\uac15\uc0c1\uc758 \uc774\uc810\uc73c\ub85c \ud070 \uc8fc\ubaa9\uc744 \ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \ucf69\uacfc \uace1\ubb3c \uc81c\ud488\uc758 \uc601\uc591\uac00\ub97c \ub192\uc774\uae30 \uc704\ud574 \uc885\uc885 \ucca8\uac00\ub429\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uc77c\ubd80 \uac15\ud654 \ucf69 \ub2e8\ubc31\uc9c8 \ubd84\ub9d0\uc5d0\ub294 \uc77c\uc815\ub7c9\uc758 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \ud568\uc720\ub418\uc5b4 \uc788\uc5b4 \uc18c\ube44\uc790\ub294 \uace0\ud488\uc9c8 \ub2e8\ubc31\uc9c8\uc744 \ubcf4\ucda9\ud558\ub294 \ub3d9\uc2dc\uc5d0 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc870\uc808 \ubc0f \ud56d\uc0b0\ud654 \ud6a8\uacfc\ub97c \ud65c\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c, \uc815\uc81c \ub610\ub294 \ucea1\uc290 \ud615\ud0dc\ub85c \uc81c\uacf5\ub418\ub294 \uac74\uac15 \ubcf4\ucda9\uc81c\uc758 \ud575\uc2ec \uc131\ubd84\uc73c\ub85c, \uc815\ud655\ud558\uace0 \uc9d1\uc911\uc801\uc778 \ubcf4\ucda9\uc774 \uac00\ub2a5\ud569\ub2c8\ub2e4. \uc2dc\uc911\uc5d0 \ud310\ub9e4\ub418\ub294 \uc77c\ubc18\uc801\uc778 \uc81c\ub2c8\uc2a4\ud14c\uc778 \uac74\uac15 \ubcf4\ucda9\uc81c\uc758 \uc815\uc81c \ub610\ub294 \ucea1\uc290\ub2f9 \uc81c\ub2c8\uc2a4\ud14c\uc778 \ud568\ub7c9\uc740 \ub2e4\uc591\ud558\uc9c0\ub9cc, \uc131\uc778\uc758 \uad8c\uc7a5 \uc77c\uc77c \uc12d\ucde8\ub7c9\uc740 \uc548\uc804\ud55c \ubc94\uc704 \ub0b4\uc5d0\uc11c \ucd5c\uc801\uc758 \uac74\uac15\uc0c1\uc758 \uc774\uc810\uc744 \ubcf4\uc7a5\ud558\uae30 \uc704\ud574 \uc720\ub9ac \uc544\uae00\ub9ac\ucf58\uc73c\ub85c\uc11c 50~100mg\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uac11\uc0c1\uc120 \uc57d\ubb3c\uc744 \ubcf5\uc6a9\ud558\ub294 \uc0ac\ub78c\uc740 \uc8fc\uc758\ud574\uc57c \ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uac11\uc0c1\uc120 \uc57d\ubb3c\uacfc \uc0c1\ud638\uc791\uc6a9\ud558\uc5ec \uc57d\ubb3c\uc758 \ud6a8\uacfc\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\uac70\ub098 \ubd80\uc791\uc6a9 \uc704\ud5d8\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778 \ubcf4\ucda9\uc81c\ub97c \ubcf5\uc6a9\ud558\uae30 \uc804\uc5d0 \uc801\uc808\ud55c \ubcf5\uc6a9\ub7c9\uc744 \uacb0\uc815\ud558\uae30 \uc704\ud574 \uc758\uc0ac \ub610\ub294 \uc804\ubb38 \uc601\uc591\uc0ac\uc640 \uc0c1\ub2f4\ud558\uc2ed\uc2dc\uc624. \uc81c\ub2c8\uc2a4\ud14c\uc778 \ud2b9\uc815 \uc9d1\ub2e8\uc5d0 \ub300\ud55c \uad6c\uccb4\uc801\uc778 \uc6a9\ub3c4\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \ud3d0\uacbd\uae30 \uc5ec\uc131\uc758 \uacbd\uc6b0, \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uce58\uc758 \uae09\uaca9\ud55c \ubcc0\ub3d9\uc740 \uc548\uba74\ud64d\uc870, \uc57c\uac04 \ubc1c\ud55c, \uace8\ub2e4\uacf5\uc99d\uacfc \uac19\uc740 \uc5ec\ub7ec \uac00\uc9c0 \ubd88\ud3b8\ud55c \uc99d\uc0c1\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubb38\uc81c\ub97c \ud574\uacb0\ud558\uae30 \uc704\ud574 \uc81c\ub2c8\uc2a4\ud14c\uc778\uacfc \uce7c\uc298, \ube44\ud0c0\ubbfc D \ubc0f \uae30\ud0c0 \uc601\uc591\uc18c\ub97c \uacb0\ud569\ud55c \ud3d0\uacbd\uae30 \uc5ec\uc131\uc744 \uc704\ud55c \uc885\ud569 \uc601\uc591 \ubcf4\ucda9\uc81c\uac00 \ucd9c\uc2dc\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uce7c\uc298\uc740 \ubf08 \uac74\uac15 \uc720\uc9c0\uc5d0 \ud544\uc218\uc801\uc774\uba70, \ube44\ud0c0\ubbfc D\ub294 \uce7c\uc298 \ud761\uc218 \ubc0f \ud65c\uc6a9\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uce58\ub97c \uc870\uc808\ud558\uace0 \ud3d0\uacbd\uae30 \uc99d\uc0c1\uc744 \uc644\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \uc885\ud569 \uc601\uc591 \ubcf4\ucda9\uc81c\ub294 \ud3d0\uacbd\uae30 \uc5ec\uc131\uc758 \uac74\uac15 \uc694\uad6c\ub97c \ub2e4\uac01\uc801\uc73c\ub85c \ucda9\uc871\ud558\uc5ec \uc774 \uc5b4\ub824\uc6b4 \uc2dc\uae30\ub97c \uc21c\uc870\ub86d\uac8c \ud5e4\uccd0\ub098\uac08 \uc218 \uc788\ub3c4\ub85d \ub3c4\uc640\uc90d\ub2c8\ub2e4.<\/p>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778 \uc2a4\ud3ec\uce20 \uc601\uc591\uc5d0\ub3c4 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uace0\uac15\ub3c4 \uc6b4\ub3d9\uc740 \uadfc\uc721 \uc190\uc0c1\uacfc \uc5fc\uc99d\uc744 \uc27d\uac8c \uc720\ubc1c\ud558\uc5ec \uc6b4\ub3d9\uc120\uc218\uc758 \ud6c8\ub828 \ud6a8\uacfc\uc640 \ud68c\ubcf5\uc744 \uc800\ud574\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \ud568\uc720\ud55c \uc2a4\ud3ec\uce20 \uc601\uc591 \uc81c\ud488\uc740 \uac15\ub825\ud55c \ud56d\uc0b0\ud654 \ubc0f \ud56d\uc5fc\uc99d \ud6a8\uacfc\ub97c \ud65c\uc6a9\ud558\uc5ec \uc6b4\ub3d9 \uc911 \uc0dd\uc131\ub418\ub294 \ud65c\uc131\uc0b0\uc18c\ub85c \uc778\ud55c \uadfc\uc721 \uc138\ud3ec \uc190\uc0c1\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uc904\uc774\uace0, \uc5fc\uc99d\uc744 \uc904\uc774\uba70, \uadfc\uc721 \ud68c\ubcf5 \ubc0f \uc131\uc7a5\uc744 \ucd09\uc9c4\ud558\uace0, \uc6b4\ub3d9\uc120\uc218\uc758 \ube60\ub978 \ud68c\ubcf5\uacfc \uacbd\uae30\ub825 \ud5a5\uc0c1\uc5d0 \ub3c4\uc6c0\uc744 \uc904 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud6a8\uacfc\ub85c \uc778\ud574 \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc2a4\ud3ec\uce20 \uc601\uc591 \uc2dc\uc7a5\uc5d0\uc11c \ud070 \uc778\uae30\ub97c \uc5bb\uc73c\uba70 \uc6b4\ub3d9\uc120\uc218\uc640 \ud53c\ud2b8\ub2c8\uc2a4 \uc560\ud638\uac00\ub4e4\uc758 \uad00\uc2ec\uc744 \ub04c\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

(II) \uc81c\uc57d \ubc0f \ud654\uc7a5\ud488 \uac1c\ubc1c<\/h3>\n

1. \uc81c\uc57d \ubd84\uc57c<\/h4>\n

\uc81c\uc57d \ubd84\uc57c\uc5d0\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778 \ud2b9\ud788 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \uce58\ub8cc \uc5f0\uad6c\uc5d0\uc11c \uc0c1\ub2f9\ud55c \uc751\uc6a9 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4. \ud604\uc7ac \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \ub2e4\uc911 \ud45c\uc801 “\uce75\ud14c\uc77c \uba54\ucee4\ub2c8\uc998”\uc744 \uae30\ubc18\uc73c\ub85c \ud55c \uc5f0\uad6c\uac00 \ud65c\ubc1c\ud788 \uc9c4\ud589\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774 “\uce75\ud14c\uc77c \uba54\ucee4\ub2c8\uc998”\uc740 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \uc5ec\ub7ec \ud45c\uc801\uacfc \uacbd\ub85c\ub97c \ud1b5\ud574 \uc791\uc6a9\ud558\uc5ec \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc758 \ubcd1\ub9ac\ud559\uc801 \uc9c4\ud589\uc5d0 \ud3ec\uad04\uc801\uc73c\ub85c \uac1c\uc785\ud560 \uc218 \uc788\uc74c\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \u03b2-\uc2dc\ud06c\ub808\ud0c0\uc81c \ud65c\uc131\uc744 \uc5b5\uc81c\ud558\uace0 \uc544\ubc00\ub85c\uc774\ub4dc \u03b2 \ub2e8\ubc31\uc9c8(A\u03b2) \uc0dd\uc131\uc744 \uac10\uc18c\uc2dc\ud0ac \ubfd0\ub9cc \uc544\ub2c8\ub77c, \ud37c\uc625\uc2dc\uc880 \uc99d\uc2dd\uc778\uc790 \ud65c\uc131\ud654 \uc218\uc6a9\uccb4 \u03b3(PPAR\u03b3)\ub97c \ud65c\uc131\ud654\uc2dc\ucf1c \uc544\ud3f4\ub9ac\ud3ec\ub2e8\ubc31\uc9c8 E(ApoE) \ubc1c\ud604\uc744 \ucd09\uc9c4\ud558\uace0 A\u03b2 \uc81c\uac70 \ubc0f \ub300\uc0ac\ub97c \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \ub610\ud55c \ud56d\uc0b0\ud654 \ubc0f \ud56d\uc5fc\uc99d \ud6a8\uacfc\ub97c \uac00\uc9c0\uace0 \uc788\uc5b4 \uc2e0\uacbd \uc5fc\uc99d\uacfc \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub85c \uc778\ud55c \uc2e0\uacbd \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4. 2\uc0c1 \uc784\uc0c1\uc2dc\ud5d8\uc740 \ucd08\uae30 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ud658\uc790\uc758 \uc778\uc9c0 \uae30\ub2a5 \uac1c\uc120\uc5d0 \ub300\ud55c \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \ud6a8\ub2a5\uc744 \uc8fc\ub85c \ud3c9\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc77c\ub828\uc758 \uc5c4\uaca9\ud55c \uc778\uc9c0 \uae30\ub2a5 \uac80\uc0ac\uc640 \uc601\uc0c1 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc81c\ub2c8\uc2a4\ud14c\uc778 \ubcf5\uc6a9 \ud6c4 \uc778\uc9c0 \ub2a5\ub825, \uae30\uc5b5\ub825, \uc2e4\ud589 \uae30\ub2a5\uc758 \ubcc0\ud654\ub97c \uad00\ucc30\ud560 \uc608\uc815\uc785\ub2c8\ub2e4. \uc774 \uc784\uc0c1\uc2dc\ud5d8\uc774 \uc131\uacf5\ud55c\ub2e4\uba74, \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc5d0 \ub300\ud55c \uc0c8\ub86d\uace0 \uc548\uc804\ud558\uba70 \ud6a8\uacfc\uc801\uc778 \uce58\ub8cc \uc635\uc158\uc744 \uc81c\uacf5\ud558\uc5ec \ub9ce\uc740 \ud658\uc790\uc758 \uc0b6\uc758 \uc9c8\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \uac00\uc871\uacfc \uc0ac\ud68c\uc758 \ubd80\ub2f4\uc744 \ub35c\uc5b4\uc904 \uc218 \uc788\uc744 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

\uc554 \uce58\ub8cc\uc5d0\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778\uacfc \ud654\ud559\uc694\ubc95 \uc57d\ubb3c\uc758 \ubcd1\uc6a9 \ud22c\uc5ec \uc2dc \uc2dc\ub108\uc9c0 \ud6a8\uacfc\uc640 \ub3c5\uc131 \uac10\uc18c \ud6a8\uacfc\uc5d0 \ub300\ud55c \uc5f0\uad6c \ub610\ud55c \uc778\uc0c1\uc801\uc778 \uacb0\uacfc\ub97c \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uc2dc\uc2a4\ud50c\ub77c\ud2f4\uc740 \ub09c\uc18c\uc554 \uce58\ub8cc\uc5d0 \ud754\ud788 \uc0ac\uc6a9\ub418\ub294 \ud654\ud559\uc694\ubc95 \uc57d\ubb3c\uc774\uc9c0\ub9cc, \uc7a5\uae30\uac04 \uc0ac\uc6a9\ud558\uba74 \uc57d\ubb3c \ub0b4\uc131\uacfc \uc2ec\uac01\ud55c \ubd80\uc791\uc6a9\uc744 \ucd08\ub798\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc2dc\uc2a4\ud50c\ub77c\ud2f4\uacfc \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \ubcd1\uc6a9 \ud22c\uc5ec\ub294 \ub09c\uc18c\uc554 \uc138\ud3ec\uc758 \uc2dc\uc2a4\ud50c\ub77c\ud2f4\uc5d0 \ub300\ud55c \ubbfc\uac10\ub3c4\ub97c \ud06c\uac8c \ud5a5\uc0c1\uc2dc\ucf1c \ud654\ud559\uc694\ubc95\uc758 \ud6a8\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc554\uc138\ud3ec\uc5d0\uc11c P-\ub2f9\ub2e8\ubc31\uc9c8\uacfc \uac19\uc740 \ub0b4\uc131 \uad00\ub828 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604\uc744 \uc5b5\uc81c\ud558\uc5ec \uc554\uc138\ud3ec\uac00 \ud654\ud559\uc694\ubc95 \uc57d\ubb3c\uc744 \uc138\ud3ec \ubc16\uc73c\ub85c \ubc30\ucd9c\ud558\ub294 \uac83\uc744 \ubc29\uc9c0\ud568\uc73c\ub85c\uc368 \uc138\ud3ec \ub0b4 \ud654\ud559\uc694\ubc95 \uc57d\ubb3c \ub18d\ub3c4\ub97c \uc99d\uac00\uc2dc\ud0a4\uace0 \ud56d\uc554 \ud6a8\uacfc\ub97c \uac15\ud654\ud569\ub2c8\ub2e4. \ub610\ud55c \uc81c\ub2c8\uc2a4\ud14c\uc778 \uba54\uc2a4\uaebc\uc6c0\uacfc \uac19\uc740 \uc2dc\uc2a4\ud50c\ub77c\ud2f4 \uc720\ubc1c \ubd80\uc791\uc6a9\uc744 \uc644\ud654\ud558\ub294 \ub370\uc5d0\ub3c4 \ud6a8\uacfc\uc801\uc785\ub2c8\ub2e4, \uad6c\ud1a0, \uace8\uc218 \uc5b5\uc81c. \uc2e0\uccb4\uc758 \uba74\uc5ed \uccb4\uacc4\uc640 \ud56d\uc0b0\ud654 \uccb4\uacc4\ub97c \uc870\uc808\ud558\uc5ec \ud56d\uc554 \ud654\ud559 \uc694\ubc95 \uc57d\ubb3c\uc5d0 \ub300\ud55c \ub0b4\uc131\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \uc815\uc0c1 \uc870\uc9c1\uacfc \uc138\ud3ec\uc758 \uc190\uc0c1\uc744 \uc904\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \ubcd1\uc6a9 \uc694\ubc95\uc740 \uc554 \ud658\uc790\uc5d0\uac8c \uc0c8\ub85c\uc6b4 \ud76c\ub9dd\uc744 \uc81c\uacf5\ud558\uba70, \uce58\ub8cc \ud6a8\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \ud1b5\uc99d\uc744 \uc904\uc774\uba70 \uc0b6\uc758 \uc9c8\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4.<\/p>\n

2. \ud654\uc7a5\ud488 \uc751\uc6a9 \ubd84\uc57c<\/h4>\n

\ud654\uc7a5\ud488 \ubd84\uc57c\uc5d0\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778 \ud0c1\uc6d4\ud55c \ub178\ud654 \ubc29\uc9c0 \ubc0f \ud56d\uc5fc\uc99d \ud6a8\uacfc \ub355\ubd84\uc5d0 \uc218\ub9ce\uc740 \uc2a4\ud0a8\ucf00\uc5b4 \uc81c\ud488\uc758 \ud575\uc2ec \ud65c\uc131 \uc131\ubd84\uc774 \ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub178\ud654\uc640 \ud658\uacbd\uc801 \uc694\uc778\uc73c\ub85c \uc778\ud574 \ud53c\ubd80\uc758 \ucf5c\ub77c\uac90\uc774 \uc810\ucc28 \ubd84\ud574\ub418\uc5b4 \ud53c\ubd80 \ucc98\uc9d0\uacfc \uc8fc\ub984 \uc99d\uac00\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uac15\ub825\ud55c \ub178\ud654 \ubc29\uc9c0 \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \ud568\uc720\ud55c \uc2a4\ud0a8\ucf00\uc5b4 \uc81c\ud488\uc5d0 \uad6d\uc18c\uc801\uc73c\ub85c \ub3c4\ud3ec\ud558\uba74 UVA\/UVB\uc5d0 \uc758\ud574 \uc720\ub3c4\ub418\ub294 \uae30\uc9c8 \uae08\uc18d\ub2e8\ubc31\ubd84\ud574\ud6a8\uc18c(MMP)\uc758 \ubc1c\ud604\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uc5b5\uc81c\ud569\ub2c8\ub2e4. MMP\ub294 \uc138\ud3ec\uc678 \uae30\uc9c8 \uc131\ubd84\uc744 \ubd84\ud574\ud558\ub294 \ud6a8\uc18c\uc785\ub2c8\ub2e4. \uc790\uc678\uc120 \uc870\uc0ac \uc2dc MMP\uc758 \ubc1c\ud604\uc774 \ud06c\uac8c \uc99d\uac00\ud558\uc5ec \ucf5c\ub77c\uac90\uacfc \uae30\ud0c0 \uc138\ud3ec\uc678 \uae30\uc9c8 \uc131\ubd84\uc758 \uacfc\ub3c4\ud55c \ubd84\ud574\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 MMP\uc758 \ubc1c\ud604\uc744 \uc5b5\uc81c\ud558\uace0 \ucf5c\ub77c\uac90 \ubd84\ud574\ub97c \uac10\uc18c\uc2dc\ucf1c \ud53c\ubd80 \ud0c4\ub825\uacfc \uacac\uace0\ud568\uc744 \uc720\uc9c0\ud558\uace0 \uc8fc\ub984\uc744 \ucd5c\uc18c\ud654\ud569\ub2c8\ub2e4. \ub9ce\uc740 \uc8fc\ub984 \uac1c\uc120 \ud06c\ub9bc\uc5d0 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \ud568\uc720\ub418\uc5b4 \uc788\uc73c\uba70, \uc7a5\uae30\uac04 \uc0ac\uc6a9 \uc2dc \uc8fc\ub984\uc774 \uac10\uc18c\ud558\uace0 \ud53c\ubd80\uac00 \ub208\uc5d0 \ub744\uac8c \ub9e4\ub048\ud574\uc9c0\uace0 \uc724\uae30\uac00 \ub098\ub294 \uac83\uc744 \uacbd\ud5d8\ud558\uac8c \ub429\ub2c8\ub2e4.<\/p>\n

\ubbfc\uac10\uc131 \ud53c\ubd80\ub97c \uac00\uc9c4 \uc0ac\ub78c\ub4e4\uc5d0\uac8c\ub294 \uc5fc\uc99d\uc774 \ud754\ud55c \uc99d\uc0c1\uc73c\ub85c, \ubc1c\uc801, \ubd80\uae30, \uac00\ub824\uc6c0, \ub530\ub054\uac70\ub9bc \ub4f1\uc774 \ub098\ud0c0\ub0a9\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \ud0c1\uc6d4\ud55c \ud56d\uc5fc\uc99d \ubc0f \ud68c\ubcf5 \ud6a8\uacfc\ub97c \uac00\uc9c0\uace0 \uc788\uc5b4 \ubbfc\uac10\uc131 \ud53c\ubd80\uc758 \uc5fc\uc99d \ubc18\uc751\uc744 \uc644\ud654\ud558\uace0 \ud53c\ubd80 \ub9c8\uc774\ud06c\ub85c\ubc14\uc774\uc634\uc758 \uade0\ud615\uc744 \uc870\uc808\ud569\ub2c8\ub2e4. \ud53c\ubd80 \ub9c8\uc774\ud06c\ub85c\ubc14\uc774\uc634\uc740 \ud53c\ubd80 \ud45c\uba74\uc5d0 \uc874\uc7ac\ud558\ub294 \ubbf8\uc0dd\ubb3c \uad70\uc9d1\uc73c\ub85c, \ud53c\ubd80 \uac74\uac15\uacfc \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ud53c\ubd80 \ub9c8\uc774\ud06c\ub85c\ubc14\uc774\uc634\uc758 \ubd88\uade0\ud615\uc740 \ub2e4\uc591\ud55c \ud53c\ubd80 \ubb38\uc81c\ub97c \uc27d\uac8c \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \ud53c\ubd80 \ub9c8\uc774\ud06c\ub85c\ubc14\uc774\uc634\uc758 \uad6c\uc131\uacfc \uae30\ub2a5\uc744 \uc870\uc808\ud558\uc5ec \uc720\ud574 \ubbf8\uc0dd\ubb3c\uc758 \uc131\uc7a5\uc744 \uc5b5\uc81c\ud558\uace0 \uc720\uc775 \ubbf8\uc0dd\ubb3c\uc758 \uc99d\uc2dd\uc744 \ucd09\uc9c4\ud558\uc5ec \ud53c\ubd80\uc758 \ubbf8\uc138 \uc0dd\ud0dc \ud658\uacbd\uc744 \uac1c\uc120\ud558\uace0 \ud53c\ubd80 \uc7a5\ubcbd \uae30\ub2a5\uc744 \uac15\ud654\ud569\ub2c8\ub2e4. \ub610\ud55c, \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc5fc\uc99d \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc870\uc808\ud558\uc5ec \uc5fc\uc99d \uc778\uc790\uc758 \ubd84\ube44\ub97c \uac10\uc18c\uc2dc\ud0a4\uace0 \uc5fc\uc99d \uc99d\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc5ec\ub4dc\ub984\uacfc \uc8fc\uc0ac(rosacea) \ud658\uc790\uc5d0\uac8c\ub3c4 \uae0d\uc815\uc801\uc778 \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \ud53c\uc9c0\uc120 \ubd84\ube44\ub97c \uac10\uc18c\uc2dc\ud0a4\uace0, \ud504\ub85c\ud53c\uc624\ub2c8\ubc15\ud14c\ub9ac\uc6c0 \uc544\ud06c\ub124\uc2a4(Propionibacterium acnes)\uc758 \uc99d\uc2dd\uc744 \uc5b5\uc81c\ud558\uba70, \uc5ec\ub4dc\ub984 \uc99d\uc0c1\uc744 \uac1c\uc120\ud558\ub294 \ud6a8\uacfc\uac00 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c \uc8fc\uc0ac \ud658\uc790\uc758 \ud53c\ubd80 \uc5fc\uc99d\uacfc \ud64d\ubc18\uc744 \uac10\uc18c\uc2dc\ucf1c \ud53c\ubd80 \uc7ac\uc0dd \ubc0f \ud68c\ubcf5\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud6a8\uacfc\ub85c \uc778\ud574 \uc81c\ub2c8\uc2a4\ud14c\uc778 \ubbfc\uac10\uc131 \ud53c\ubd80 \uad00\ub9ac \ubc0f \ubb38\uc81c\uc131 \ud53c\ubd80 \uc7ac\uc0dd\uc744 \uc704\ud55c \ud654\uc7a5\ud488\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\uc5b4 \ub9ce\uc740 \uc18c\ube44\uc790\uc758 \ud53c\ubd80 \uace0\ubbfc\uc744 \ud574\uacb0\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc548\uc804\uc131 \ud3c9\uac00 \ubc0f \uc704\ud5d8 \uacbd\uace0<\/h2>\n

\"\"<\/p>\n

(I) \ub3c5\uc131\ud559 \ub370\uc774\ud130 \ubc0f \uc801\uc808\ud55c \uc6a9\ub7c9<\/h3>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \uc548\uc804\uc131 \ud3c9\uac00\ub294 \uc0ac\uc6a9 \uc2dc \uc911\uc694\ud55c \uace0\ub824 \uc0ac\ud56d\uc785\ub2c8\ub2e4. \uae09\uc131 \ub3c5\uc131 \uc2dc\ud5d8\uc740 \uc548\uc804\uc131 \ud3c9\uac00\uc758 \ud575\uc2ec \ub2e8\uacc4\uc785\ub2c8\ub2e4. \ub9c8\uc6b0\uc2a4\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \uae09\uc131 \ub3c5\uc131 \uc2dc\ud5d8 \uacb0\uacfc, \uc911\uac04 \uce58\uc0ac\ub7c9(LD\u2085\u2080)\uc774 5,000mg\/kg\uc744 \ucd08\uacfc\ud588\uc2b5\ub2c8\ub2e4. \uad00\ub828 \ub3c5\uc131 \ubd84\ub958 \uae30\uc900\uc5d0 \ub530\ub974\uba74, \uc774\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \uc0ac\uc2e4\uc0c1 \ubb34\ub3c5\uc131 \ubb3c\uc9c8\ub85c \ubd84\ub958\ub428\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. \uc989, \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \ub2e8\ud68c \uace0\uc6a9\ub7c9\uc73c\ub85c \uc12d\ucde8\ud560 \uacbd\uc6b0 \uae09\uc131 \ub3c5\uc131 \ubc0f \uc0ac\ub9dd \uc704\ud5d8\uc774 \ub0ae\uc74c\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \uc7a5\uae30\uac04 \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc12d\ucde8\uc758 \uc548\uc804\uc131\uc744 \uac04\uacfc\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc7a5\uae30\uac04(6\uac1c\uc6d4 \uc774\uc0c1) \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc12d\ucde8\ub294 \uac11\uc0c1\uc120 \uae30\ub2a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \uac11\uc0c1\uc120 \ud638\ub974\ubaac \ud569\uc131\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\ub294 \ud6a8\uc18c\uc778 \uac11\uc0c1\uc120 \uacfc\uc0b0\ud654\ud6a8\uc18c\uc758 \ud65c\uc131\uc744 \uc5b5\uc81c\ud558\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \uac11\uc0c1\uc120 \uacfc\uc0b0\ud654\ud6a8\uc18c \ud65c\uc131 \uc5b5\uc81c\ub294 \uc815\uc0c1\uc801\uc778 \uac11\uc0c1\uc120 \ud638\ub974\ubaac \ud569\uc131\uc744 \ubc29\ud574\ud558\uc5ec \uac11\uc0c1\uc120 \uae30\ub2a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uac11\uc0c1\uc120 \uae30\ub2a5\uc774 \uc774\ubbf8 \ube44\uc815\uc0c1\uc778 \uac11\uc0c1\uc120 \uc9c8\ud658 \ud658\uc790\uc758 \uacbd\uc6b0, \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc12d\ucde8 \uc2dc \uc8fc\uc758\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c \uac11\uc0c1\uc120 \uc9c8\ud658 \ud658\uc790\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \ud558\ub8e8 50mg \ubbf8\ub9cc\uc73c\ub85c \uc12d\ucde8\ud558\uace0 \uac11\uc0c1\uc120 \uc790\uadf9 \ud638\ub974\ubaac(TSH) \uc218\uce58\ub97c \uc815\uae30\uc801\uc73c\ub85c \ubaa8\ub2c8\ud130\ub9c1\ud558\ub294 \uac83\uc774 \uc88b\uc2b5\ub2c8\ub2e4. TSH\ub294 \uac11\uc0c1\uc120 \uae30\ub2a5\uc758 \ud575\uc2ec \uc9c0\ud45c\uc785\ub2c8\ub2e4. TSH \uc218\uce58\ub97c \uc815\uae30\uc801\uc73c\ub85c \ubaa8\ub2c8\ud130\ub9c1\ud558\uba74 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \uac11\uc0c1\uc120 \uae30\ub2a5\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc744 \uc2dc\uae30\uc801\uc808\ud558\uac8c \ud30c\uc545\ud560 \uc218 \uc788\uc73c\uba70, \uc774\ub97c \ud1b5\ud574 \ud658\uc790\uc758 \uac74\uac15\uacfc \uc548\uc804\uc744 \ubcf4\uc7a5\ud558\uae30 \uc704\ud574 \uc12d\ucde8\ub7c9\uc744 \uc870\uc808\ud558\uac70\ub098 \uc801\uc808\ud55c \uce58\ub8cc \ubc29\ubc95\uc744 \uacb0\uc815\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

(II) \uae08\uae30\uc99d \ubc0f \uc0c1\ud638\uc791\uc6a9<\/h3>\n

1. \uc784\uc2e0 \ubc0f \uc218\uc720<\/h4>\n

\uc784\uc2e0 \ubc0f \uc218\uc720 \uc911 \uc5ec\uc131\uc758 \uc2e0\uccb4\ub294 \ub3c5\ud2b9\ud55c \uc0dd\ub9ac\uc801 \uc0c1\ud0dc\uc5d0 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \uae30\uac04 \ub3d9\uc548 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \uc12d\ucde8\ud558\uba74 \ud0dc\uc544 \ub610\ub294 \uc601\uc544 \ubc1c\ub2ec\uc5d0 \uc7a0\uc7ac\uc801\uc778 \uc704\ud5d8\uc744 \ucd08\ub798\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub3d9\ubb3c \uc2e4\ud5d8 \uacb0\uacfc, \uc81c\ub2c8\uc2a4\ud14c\uc778 \ud0dc\ubc18\uc744 \ud1b5\uacfc\ud558\uc5ec \ubaa8\uccb4\ub85c\ubd80\ud130 \ud0dc\uc544\ub85c \uc720\uc785\ub420 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ud604\uc7ac \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \ud0dc\uc544 \uae30\ud615\uc744 \uc720\ubc1c\ud55c\ub2e4\ub294 \uba85\ud655\ud55c \uc99d\uac70\ub294 \uc5c6\uc9c0\ub9cc, \ud0dc\uc544 \ub0b4\ubd84\ube44\uacc4 \ubc0f \uae30\ud0c0 \ubc1c\ub2ec \uacfc\uc815\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc73c\ubbc0\ub85c \uc784\uc0b0\ubd80\ub294 \uac74\uac15\ud55c \ud0dc\uc544 \ubc1c\ub2ec\uc744 \uc704\ud574 \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc12d\ucde8\ub97c \ud53c\ud558\ub294 \uac83\uc774 \uc88b\uc2b5\ub2c8\ub2e4. \ubaa8\uc720 \uc218\uc720 \uc911\uc778 \uc5ec\uc131\uc758 \uacbd\uc6b0, \ubaa8\uc720\ub97c \ud1b5\ud574 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \uc601\uc544\uc5d0\uac8c \uc804\ub2ec\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc601\uc544\uc758 \uc2e0\uccb4 \uae30\ub2a5\uc740 \uc544\uc9c1 \uc644\uc804\ud788 \ubc1c\ub2ec\ub418\uc9c0 \uc54a\uc558\uace0 \ub2e4\uc591\ud55c \ubb3c\uc9c8\uc744 \ub300\uc0ac\ud558\uace0 \ub0b4\uc57d\ud558\ub294 \ub2a5\ub825\uc774 \ubd80\uc871\ud558\ubbc0\ub85c, \ubaa8\uc720 \uc218\uc720 \uc911\uc778 \uc5ec\uc131\uc740 \uc601\uc544\uc758 \uac74\uac15\uc5d0 \uc545\uc601\ud5a5\uc744 \ubbf8\uce58\uc9c0 \uc54a\ub3c4\ub85d \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc12d\ucde8\ub97c \ud53c\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

2. \uc57d\ubb3c \uc0c1\ud638\uc791\uc6a9<\/h4>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778 \uc77c\ubd80 \uc57d\ubb3c\uacfc \uc0c1\ud638\uc791\uc6a9\ud558\ubbc0\ub85c \uc784\uc0c1 \uc0ac\uc6a9 \uc2dc \ud2b9\ubcc4\ud55c \uc8fc\uc758\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc640\ud30c\ub9b0\uacfc \uac19\uc740 \ud56d\uc751\uace0\uc81c\uc758 \ud6a8\uacfc\ub97c \uc99d\uac15\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc640\ud30c\ub9b0\uc740 \ube44\ud0c0\ubbfc K \uc758\uc874\uc131 \uc751\uace0 \uc778\uc790\uc758 \ud569\uc131\uc744 \uc5b5\uc81c\ud558\uc5ec \uc791\uc6a9\ud558\ub294 \uc77c\ubc18\uc801\uc778 \ud56d\uc751\uace0\uc81c\uc785\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc640\ud30c\ub9b0\uc758 \ub300\uc0ac\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\uac70\ub098 \uc751\uace0 \uc778\uc790\uc5d0 \ub300\ud55c \uc5b5\uc81c \ud6a8\uacfc\ub97c \uc99d\uac15\uc2dc\ucf1c \ucd9c\ud608 \uc704\ud5d8\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc640\ud30c\ub9b0\uacfc \uac19\uc740 \ud56d\uc751\uace0\uc81c\ub97c \ubcf5\uc6a9\ud558\ub294 \ud658\uc790\ub294 \uc758\uc0ac\uc758 \uc5c4\uaca9\ud55c \uc9c0\ub3c4 \ud558\uc5d0 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \ubcf5\uc6a9\ud574\uc57c \ud569\ub2c8\ub2e4. \uc758\uc0ac\ub294 \ud658\uc790\uc758 \uc751\uace0 \uae30\ub2a5 \ubc0f \uc57d\ubb3c \uc6a9\ub7c9\uacfc \uac19\uc740 \ud2b9\uc815 \uc0c1\ud669\uc5d0 \ub530\ub77c \uc704\ud5d8\uc744 \uc2e0\uc911\ud558\uac8c \ud3c9\uac00\ud558\uace0 \uc548\uc804\ud55c \uc0ac\uc6a9\uc744 \uc704\ud574 \uc57d\ubb3c \uc694\ubc95\uc744 \uc870\uc815\ud560 \uac83\uc785\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \ub300\uccb4 \uc694\ubc95\uacfc \ubcd1\uc6a9\ud558\uba74 \uc790\uad81\ub0b4\ub9c9 \uc99d\uc2dd\uc99d\uc758 \uc704\ud5d8\uc774 \uc99d\uac00\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc5d0\uc2a4\ud2b8\ub85c\uac90 \ub300\uccb4 \uc694\ubc95\uc740 \ud3d0\uacbd \uc99d\ud6c4\uad70\uacfc \uac19\uc740 \uc9c8\ud658\uc5d0 \ub300\ud55c \uce58\ub8cc\ubc95\uc73c\ub85c, \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uce58 \uac10\uc18c\ub85c \uc778\ud55c \ubd88\ud3b8\ud568\uc744 \uc644\ud654\ud558\uae30 \uc704\ud574 \uc678\uc778\uc131 \uc5d0\uc2a4\ud2b8\ub85c\uac90\uc744 \uc0ac\uc6a9\ud569\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc790\uccb4\ub294 \uc5d0\uc2a4\ud2b8\ub85c\uac90\uacfc \uc720\uc0ac\ud55c \ud6a8\uacfc\ub97c \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc5d0\uc2a4\ud2b8\ub85c\uac90 \ub300\uccb4 \uc694\ubc95\uacfc \ubcd1\uc6a9\ud558\uba74 \uccb4\ub0b4 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uce58\uac00 \uc99d\uac00\ud558\uc5ec \uc790\uad81\ub0b4\ub9c9\uc744 \uacfc\ub3c4\ud558\uac8c \uc790\uadf9\ud558\uc5ec \uc790\uad81\ub0b4\ub9c9 \uc99d\uc2dd\uc99d\uc744 \uc720\ubc1c\ud558\uace0 \uc2ec\uc9c0\uc5b4 \uc790\uad81\ub0b4\ub9c9\uc554\uc758 \uc704\ud5d8\uae4c\uc9c0 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc704\ud5d8\uc744 \ud53c\ud558\uae30 \uc704\ud574 \uc81c\ub2c8\uc2a4\ud14c\uc778\uacfc \uc5d0\uc2a4\ud2b8\ub85c\uac90 \ub300\uccb4 \uc694\ubc95\uc740 \uc0c1\ud638\uc791\uc6a9\uc744 \ucd5c\uc18c\ud654\ud558\uae30 \uc704\ud574 \ucd5c\uc18c 2\uc2dc\uac04 \uac04\uaca9\uc744 \ub450\uace0 \ubcf5\uc6a9\ud558\ub294 \uac83\uc774 \uc88b\uc2b5\ub2c8\ub2e4. \uce58\ub8cc \uae30\uac04 \ub3d9\uc548 \uc758\uc0ac\ub294 \uc815\uae30\uc801\uc778 \ubd80\uc778\uacfc \uac80\uc9c4\uacfc \ucd08\uc74c\ud30c \uac80\uc0ac\ub97c \ud1b5\ud574 \ud658\uc790\uc758 \uc790\uad81\ub0b4\ub9c9 \uc0c1\ud0dc\ub97c \uba74\ubc00\ud788 \ubaa8\ub2c8\ud130\ub9c1\ud558\uc5ec \uc7a0\uc7ac\uc801\uc778 \ubb38\uc81c\ub97c \uc2e0\uc18d\ud558\uac8c \ud30c\uc545\ud558\uace0 \ud574\uacb0\ud558\uba70 \ud658\uc790\uc758 \uac74\uac15\uc744 \ubcf4\ud638\ud569\ub2c8\ub2e4.<\/p>\n

\uc5f0\uad6c \uc9c4\ud589 \uc0c1\ud669 \ubc0f \ud5a5\ud6c4 \uc804\ub9dd\"\"<\/h2>\n

(I) \ucd5c\ucca8\ub2e8 \uae30\uc220 \ud601\uc2e0<\/h3>\n

\ub9ac\ud3ec\uc880 \ucea1\uc290\ud654 \uae30\uc220\uc740 \uc804\ub2ec \uc2dc\uc2a4\ud15c \ucd5c\uc801\ud654\uc5d0 \uc788\uc5b4 \uc0c1\ub2f9\ud55c \uc9c4\uc804\uc744 \uc774\ub8e8\uc5c8\uc2b5\ub2c8\ub2e4. \uae30\uc874\uc758 \uc81c\ub2c8\uc2a4\ud14c\uc778 \uace0\uc720\ud55c \ubb3c\ub9ac\ud654\ud559\uc801 \ud2b9\uc131\uc73c\ub85c \uc778\ud574 \uccb4\ub0b4 \uc0dd\uccb4\uc774\uc6a9\ub960\uc774 \ub0ae\uc544 \uadf8 \uc7a0\uc7ac\ub825\uc774 \uc81c\ud55c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ub9ac\ud3ec\uc880 \ucea1\uc290\ud654\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \ub9ac\ud3ec\uc880 \ub0b4\uc5d0 \ucea1\uc290\ud654\ud558\uc5ec \ub098\ub178 \ud06c\uae30\uc758 \uc6b4\ubc18\uccb4 \uc2dc\uc2a4\ud15c\uc744 \ud615\uc131\ud558\uc5ec \uc6a9\ud574\ub3c4\uc640 \uc548\uc815\uc131\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \ud5a5\uc0c1\uc2dc\ucf1c \uc0dd\uccb4\uc774\uc6a9\ub960\uc744 \ud06c\uac8c \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc774 \ucca8\ub2e8 \ub9ac\ud3ec\uc880 \ucea1\uc290\ud654 \uae30\uc220\uc744 \uc0ac\uc6a9\ud558\uba74 \ucea1\uc290\ud654\ub418\uc9c0 \uc54a\uc740 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc5d0 \ube44\ud574 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \uc0dd\uccb4\uc774\uc6a9\ub960\uc774 3\ubc30 \uc99d\uac00\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc774\ub97c \ud1b5\ud574 \uccb4\ub0b4\uc5d0\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \ud761\uc218 \ubc0f \ud65c\uc6a9 \ud6a8\uc728\uc774 \ub354\uc6b1 \ud5a5\uc0c1\ub418\uc5b4 \uc758\ud559 \ubc0f \uc601\uc591\ud559 \ubd84\uc57c\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \uac00\ub2a5\uc131\uc744 \uc5f4\uc5c8\uc2b5\ub2c8\ub2e4.
\n\uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70\uc9d1\uc744 \ud45c\uc801\uc73c\ub85c \ud558\ub294 \ub9c8\uc774\ud06c\ub85c\ucea1\uc290 \uc81c\ud615 \ub610\ud55c \uace0\uc720\ud55c \uc7a5\uc810\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4. \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70\uc9d1\uc740 \uc778\uccb4 \uac74\uac15\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\uba70 \uc218\ub9ce\uc740 \uc9c8\ubcd1\uc758 \ubc1c\ubcd1 \ubc0f \uc9c4\ud589\uacfc \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \ub9c8\uc774\ud06c\ub85c\ucea1\uc290 \uc81c\ud615\uc740 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70\uc744 \uc815\ubc00\ud558\uac8c \ud45c\uc801\ud654\ud558\uc5ec \uad6c\uc870\uc640 \uae30\ub2a5\uc744 \uc870\uc808\ud558\uc5ec \uac74\uac15\uc0c1\uc758 \uc774\uc810\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \ub9c8\ube48\ube0c\ub77c\uc774\uc5b8\ud2f0\uc544 \ud3ec\ub974\ud14d\uc2dc\uac90\uc2a4(Marvinbryantia formatexigens)\ub77c\ub294 \ubc15\ud14c\ub9ac\uc544\uc758 \uc874\uc7ac\ube44\ub97c \ud2b9\uc774\uc801\uc73c\ub85c \uc870\uc808\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc5fc\uc99d \uc0c1\ud0dc\uc5d0\uc11c\ub294 \ub9c8\ube48\ube0c\ub77c\uc774\uc5b8\ud2f0\uc544 \ud3ec\ub974\ud14d\uc2dc\uac90\uc2a4\uc758 \uc874\uc7ac\ube44\uac00 \uc885\uc885 \ubcc0\ud569\ub2c8\ub2e4. \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70\uc744 \ud45c\uc801\uc73c\ub85c \ud558\ub294 \ub9c8\uc774\ud06c\ub85c\ucea1\uc290\ud654 \uc81c\ud615\uc740 \uc874\uc7ac\ube44\ub97c \uc815\uc0c1 \uc218\uc900\uc73c\ub85c \ud68c\ubcf5\uc2dc\ucf1c \ud56d\uc5fc\uc99d \ud6a8\uacfc\ub97c \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \uc5fc\uc99d\uc131 \uc9c8\ud658 \uce58\ub8cc\uc5d0 \uc0c8\ub85c\uc6b4 \uc804\ub7b5\uc744 \uc81c\uc2dc\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud569\uc131\uc0dd\ubb3c\ud559\uc758 \uc751\uc6a9\uc740 \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc0dd\uc0b0\uc5d0 \ud601\uba85\uc744 \uc77c\uc73c\ucf30\uc2b5\ub2c8\ub2e4. \uc720\uc804\uc790 \uc870\uc791 \ud6a8\ubaa8\ub97c \uc774\uc6a9\ud55c \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \uc774\uc885 \ud569\uc131\uc740 \ud569\uc131\uc0dd\ubb3c\ud559\uc758 \uc911\uc694\ud55c \ubc1c\uc804\uc785\ub2c8\ub2e4. \uc804\ud1b5\uc801\uc73c\ub85c \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc8fc\ub85c \uc2dd\ubb3c\uc5d0\uc11c \ucd94\ucd9c\ub418\ub294\ub370, \uc774\ub294 \uacc4\uc808 \ubc0f \uc9c0\uc5ed\uc801 \uc81c\uc57d\uacfc \ubd88\uc548\uc815\ud55c \uc218\ud655\ub7c9\uacfc \uac19\uc740 \uc0c1\ub2f9\ud55c \ud55c\uacc4\ub97c \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc720\uc804\uc790 \uc870\uc791 \ud6a8\ubaa8\ub97c \uc774\uc6a9\ud55c \uc774\uc885 \ud569\uc131\uc740 \uc774\ub7ec\ud55c \ud55c\uacc4\ub97c \uadf9\ubcf5\ud569\ub2c8\ub2e4. \uacc4\uc808\uc801 \uc758\uc874\uc131\uc774 \uc5c6\uc73c\uba70 \uc5b8\uc81c\ub4e0\uc9c0 \ub300\ub7c9 \uc0dd\uc0b0\uc774 \uac00\ub2a5\ud569\ub2c8\ub2e4. \ud6a8\ubaa8 \uc138\ud3ec\uc758 \uc720\uc804\uc790 \ud3b8\uc9d1 \ubc0f \ub300\uc0ac \uacf5\ud559\uc744 \ud1b5\ud574 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \ud6a8\uc728\uc801\uc778 \ud569\uc131\uc774 \uac00\ub2a5\ud569\ub2c8\ub2e4. \uc774 \ubc29\ubc95\uc740 \uae30\uc874 \uc2dd\ubb3c \ucd94\ucd9c\ubc95\uc5d0 \ube44\ud574 \uc0dd\uc0b0 \ube44\uc6a9\uc744 40% \uc808\uac10\ud569\ub2c8\ub2e4. \uc774\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \uc2dc\uc7a5 \uacbd\uc7c1\ub825\uc744 \uac15\ud654\ud560 \ubfd0\ub9cc \uc544\ub2c8\ub77c \ub300\uaddc\ubaa8 \uc801\uc6a9\uc744 \uc704\ud55c \ud0c4\ud0c4\ud55c \uae30\ubc18\uc744 \ub9c8\ub828\ud569\ub2c8\ub2e4.<\/p>\n

(II) \ub17c\ub780\uacfc \uacfc\uc81c<\/h3>\n

\uac1c\uc778\ucc28\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \ub300\uc0ac \ubc0f \ud6a8\uacfc\uc5d0 \uc0c1\ub2f9\ud55c \uc601\ud5a5\uc744 \ubbf8\uce58\uba70, \ud2b9\ud788 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\ucd1d\uc758 \ub300\uc0ac \ub2a5\ub825 \ucc28\uc774\uac00 \ud575\uc2ec \uc694\uc778\uc785\ub2c8\ub2e4. \ub300\uc0ac \uacfc\uc815\uc5d0\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\ucd1d\uc5d0 \uc758\ud574 \uc5d0\ucfe0\uc62c\ub85c \uc804\ud658\ub418\ub294\ub370, \uc5d0\ucfe0\uc62c\uc740 \uc0dd\ubb3c\ud559\uc801 \ud65c\uc131\uc774 \ub354 \uac15\ud558\uace0 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \uac74\uac15 \ud6a8\ub2a5\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\ucd1d\uc758 \uad6c\uc131\uacfc \ub300\uc0ac \ub2a5\ub825\uc740 \uac1c\uc778\ub9c8\ub2e4 \uc0c1\ub2f9\ud55c \ucc28\uc774\ub97c \ubcf4\uc774\uba70, \uc774\ub85c \uc778\ud574 \uc5d0\ucfe0\uc62c \uc0dd\uc131\ub7c9\uc5d0\ub3c4 \uc0c1\ub2f9\ud55c \ucc28\uc774\uac00 \ubc1c\uc0dd\ud569\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc778\uad6c\uc758 \uc57d 30%\ub294 “\ube44\uc804\ud658\uc790” \ud45c\ud604\ud615\uc744 \ubcf4\uc774\ub294\ub370, \uc774\ub294 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\ucd1d\uc774 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc744 \uc5d0\ucfe0\uc62c\ub85c \ud6a8\uacfc\uc801\uc73c\ub85c \uc804\ud658\ud558\uc9c0 \ubabb\ud558\uc5ec \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \ud6a8\ub2a5\uc774 \uc81c\ud55c\ub428\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. \uc774 \ubb38\uc81c\ub97c \ud574\uacb0\ud558\uae30 \uc704\ud574 \uc720\uc804\uc790 \uac80\uc0ac\uac00 \ud6a8\uacfc\uc801\uc778 \ub3c4\uad6c\uac00 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uac1c\uc778\uc758 \uc720\uc804 \uc815\ubcf4\ub97c \ubd84\uc11d\ud568\uc73c\ub85c\uc368 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70\uc758 \ub300\uc0ac \ub2a5\ub825\uc744 \ud30c\uc545\ud558\uace0, \uc774\ub97c \ud1b5\ud574 \ubaa9\ud45c \uc81c\ub2c8\uc2a4\ud14c\uc778 \ubcf4\ucda9\uc744 \uc704\ud55c \uc9c0\uce68\uc744 \uc81c\uacf5\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc720\uc804\uc790 \uac80\uc0ac \uacb0\uacfc\ub97c \ubc14\ud0d5\uc73c\ub85c, \uc81c\ub2c8\uc2a4\ud14c\uc778 \ube44\uc804\ud658\uc790\uc758 \uacbd\uc6b0, \uc81c\ub2c8\uc2a4\ud14c\uc778 \ubcf4\ucda9 \uc6a9\ub7c9\uc744 \uc870\uc808\ud558\uac70\ub098 \ub2e4\ub978 \ubcf4\ucda9 \ubc29\ubc95\uc744 \ud65c\uc6a9\ud558\uc5ec \uccb4\ub0b4 \ub300\uc0ac \ubc0f \ud65c\uc6a9 \ud6a8\uc728\uc744 \uac1c\uc120\ud558\uace0 \ucd5c\uc801\uc758 \uac74\uac15 \ud6a8\uacfc\ub97c \ubcf4\uc7a5\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud604\uc7ac \uc7a5\uae30\uc801\uc778 \ud6a8\uacfc\uc5d0 \ub300\ud55c \ub370\uc774\ud130\uc5d0\ub294 \uc0c1\ub2f9\ud55c \ucc28\uc774\uac00 \uc788\uc2b5\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778 \ub9ce\uc740 \uc5f0\uad6c\uc5d0\uc11c \uc720\ub9dd\ud55c \ub2e8\uae30 \uac74\uac15\uc0c1\uc758 \uc774\uc810\uc744 \uc785\uc99d\ud588\uc9c0\ub9cc, \uc7a5\uae30\uc801\uc778 \ud6a8\uacfc\ub97c \uc870\uc0ac\ud55c \uc5f0\uad6c\ub294 \uc0c1\ub300\uc801\uc73c\ub85c \uc801\uc2b5\ub2c8\ub2e4. \uae30\uc874\uc758 \uc784\uc0c1 \uc5f0\uad6c\ub294 \ub300\ubd80\ubd84 \ub2e8\uae30\uc801\uc774\uba70, \uc77c\ubc18\uc801\uc73c\ub85c 2\ub144 \ubbf8\ub9cc\uc758 \uae30\uac04\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc720\ubc29 \ubc00\ub3c4, \uc790\uad81\ub0b4\ub9c9 \ubc0f \uae30\ud0c0 \uc694\uc778\uc5d0 \ub300\ud55c \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \uc7a5\uae30\uc801\uc778 \ud6a8\uacfc\ub294 \uc720\ubc29\uc554 \ubc0f \uc790\uad81\ub0b4\ub9c9\uc554 \uc704\ud5d8\uacfc \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\uc744 \uc218 \uc788\uc73c\ubbc0\ub85c \ud2b9\ud788 \uc8fc\ubaa9\uc744 \ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ub370\uc774\ud130 \ucc28\uc774\ub97c \uba54\uc6b0\uae30 \uc704\ud574\uc11c\ub294 \uc7a5\uae30\uac04\uc5d0 \uac78\uccd0 \ub300\uaddc\ubaa8 \uc9d1\ub2e8\uc744 \ucd94\uc801\ud558\uace0, \uc0c1\uc138\ud55c \ub370\uc774\ud130\ub97c \uc218\uc9d1\ud558\uba70, \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \uc7a5\uae30\uc801\uc778 \uc548\uc804\uc131 \ubc0f \ud6a8\ub2a5\uc5d0 \ub300\ud55c \uc2ec\uce35 \ubd84\uc11d\uc744 \uc218\ud589\ud558\ub294 \ub300\uaddc\ubaa8 \ucf54\ud638\ud2b8 \uc5f0\uad6c\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc5f0\uad6c\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \uc791\uc6a9 \uae30\uc804\uacfc \uc7a0\uc7ac\uc801 \uc704\ud5d8\uc5d0 \ub300\ud55c \ubcf4\ub2e4 \ud3ec\uad04\uc801\uc778 \uc774\ud574\ub97c \uc81c\uacf5\ud558\uace0, \uc801\uc808\ud55c \uc0ac\uc6a9\uc744 \uc704\ud55c \ubcf4\ub2e4 \uacfc\ud559\uc801\uc774\uace0 \uc2e0\ub8b0\ud560 \uc218 \uc788\ub294 \uae30\ubc18\uc744 \uc81c\uacf5\ud558\uba70, \uc7a5\uae30\uac04 \uc0ac\uc6a9 \uc2dc \ubc1c\uc0dd\ud560 \uc218 \uc788\ub294 \ubd80\uc791\uc6a9\uc744 \uc608\ubc29\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\"\"<\/p>\n

\ub300\ud45c\uc801\uc778 \ucc9c\uc5f0 \uc2dd\ubb3c\uc131 \uc5d0\uc2a4\ud2b8\ub85c\uac90\uc778 \uc81c\ub2c8\uc2a4\ud14c\uc778 \ub2e4\uc911 \ud45c\uc801 \uc0dd\ub9ac\ud65c\uc131\uc744 \ud1b5\ud574 \ud3d0\uacbd \uad00\ub9ac, \uc2e0\uacbd \ubcf4\ud638, \uadf8\ub9ac\uace0 \ub300\uc0ac \uc9c8\ud658 \uc608\ubc29\uc5d0 \uc0c8\ub85c\uc6b4 \uae38\uc744 \uc5f4\uc5b4\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4. \ud3d0\uacbd \uad00\ub9ac\uc5d0\uc11c \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc548\uba74\ud64d\uc870, \uc57c\uac04 \ubc1c\ud55c\uacfc \uac19\uc740 \uc99d\uc0c1\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uc644\ud654\ud558\uace0, \uc9c0\uc9c8 \uc218\uce58\ub97c \uc870\uc808\ud558\uba70, \uc2ec\ud608\uad00 \uc9c8\ud658 \uc704\ud5d8\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc2e0\uacbd \ubcf4\ud638 \uce21\uba74\uc5d0\uc11c\ub294 \uc54c\uce20\ud558\uc774\uba38\ubcd1\uacfc \uac19\uc740 \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658\uc5d0 \ub300\ud55c \uc911\uc7ac\uc801 \uce58\ub8cc\ub85c\uc11c \uc7a0\uc7ac\ub825\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4. \ub300\uc0ac \uc9c8\ud658 \uc608\ubc29\uc5d0\uc11c\ub294 \uc9c0\uc9c8 \ub300\uc0ac \uc870\uc808\uacfc \uac19\uc740 \uae30\uc804\uc744 \ud1b5\ud574 \uae0d\uc815\uc801\uc778 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uad70\uc744 \ud45c\uc801\uc73c\ub85c \ud558\ub294 \ub9ac\ud3ec\uc880 \ucea1\uc290\ud654 \ubc0f \ubbf8\uc138 \ucea1\uc290\ud654 \uc81c\ud615\uacfc \uac19\uc740 \uc804\ub2ec \uae30\uc220\uc758 \uc9c0\uc18d\uc801\uc778 \ud601\uc2e0\uacfc \ucd95\uc801\ub418\ub294 \uc784\uc0c1\uc801 \uc99d\uac70\ub97c \ud1b5\ud574 \uc81c\ub2c8\uc2a4\ud14c\uc778 \ub2e8\uc21c\ud55c \uac74\uac15 \ubcf4\uc870 \uc2dd\ud488\uc5d0\uc11c \uc815\ubc00 \uc758\ub8cc \uc911\uc7ac\ub85c \ubc1c\uc804\ud560 \uc7a0\uc7ac\ub825\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \uc0ac\uc6a9\uc740 \uac1c\uc778\uc758 \uac74\uac15 \uc0c1\ud0dc\uc5d0 \ub530\ub77c \uacfc\ud559\uc801\uc73c\ub85c \ud3c9\uac00\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4. \uac1c\uc778\ucc28\uac00 \uc788\ub294 \ub300\uc0ac \ubc0f \ud6a8\uacfc\uc758 \uc601\ud5a5\uacfc \uc7a5\uae30\uc801\uc778 \ub370\uc774\ud130 \ubd80\uc871\uc744 \uace0\ub824\ud560 \ub54c, \ub9f9\uac80 \ubcf4\ucda9\uc740 \uc7a0\uc7ac\uc801 \uc704\ud5d8\uc744 \uc218\ubc18\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\ucd1d\uc758 \ub300\uc0ac \ub2a5\ub825\uc774 \ub2e4\ub978 \uac1c\uc778\ub9c8\ub2e4 \ubcf4\ucda9 \ud6a8\uacfc\uac00 \ub2e4\ub97c \uc218 \uc788\uc73c\uba70, \uc7a5\uae30\uac04 \ubcf5\uc6a9 \uc2dc \uc720\ubc29 \ubc00\ub3c4 \ubc0f \uc790\uad81\ub0b4\ub9c9\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc740 \uc544\uc9c1 \uba85\ud655\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \ubcf5\uc6a9 \uc804\uc5d0 \uc790\uc2e0\uc758 \uac74\uac15 \uc0c1\ud0dc\ub97c \ucda9\ubd84\ud788 \uc774\ud574\ud558\uace0 \uc804\ubb38 \uc758\uc0ac \ub610\ub294 \uc601\uc591\uc0ac\uc640 \uc0c1\ub2f4\ud558\uc2dc\uae30 \ubc14\ub78d\ub2c8\ub2e4.<\/p>\n

\uc81c\ub2c8\uc2a4\ud14c\uc778\uc5d0 \ub300\ud55c \ud5a5\ud6c4 \uc5f0\uad6c\ub294 \uc7a5\uae30\uc801\uc778 \uc548\uc804\uc131\uacfc \uc791\uc6a9 \uae30\uc804\uc5d0 \ub300\ud55c \uc2ec\uce35 \ubd84\uc11d\uc5d0 \uc911\uc810\uc744 \ub450\uc5b4\uc57c \ud569\ub2c8\ub2e4. \ub300\uaddc\ubaa8 \ucf54\ud638\ud2b8 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc7a5\uae30\uc801\uc778 \uc548\uc804\uc131\uc744 \uba85\ud655\ud788 \ud558\uace0, \uc720\uc804\uc790 \uac80\uc0ac, \ub2e8\ubc31\uc9c8\uccb4\ud559, \ub300\uc0ac\uccb4\ud559 \ub4f1\uc758 \ucca8\ub2e8 \uae30\uc220\uc744 \ud65c\uc6a9\ud558\uc5ec \uccb4\ub0b4 \uc791\uc6a9 \uae30\uc804\uc744 \uc644\uc804\ud788 \uaddc\uba85\ud560 \uac83\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubc29\ubc95\uc744 \ud1b5\ud574\uc11c\ub9cc \uc774 “\uc2dd\ubb3c\uc758 \ud669\uae08”\uc758 \uac00\uce58\ub97c \ucd5c\ub300\ud55c \ud65c\uc6a9\ud558\uc5ec \uc778\ub958 \uac74\uac15\uc5d0 \uae30\uc5ec\ud558\uace0 \ub2e4\uc591\ud55c \uac74\uac15 \ubb38\uc81c\uc5d0 \ub300\ud55c \ub354\uc6b1 \ud6a8\uacfc\uc801\uc778 \ud574\uacb0\ucc45\uc744 \uc81c\uacf5\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n","protected":false},"excerpt":{"rendered":"

\uc81c\ub2c8\uc2a4\ud14c\uc778 \ud654\ud559\uc801\uc73c\ub85c 5,7-\ub514\ud558\uc774\ub4dc\ub85d\uc2dc-3-(4-\ud558\uc774\ub4dc\ub85d\uc2dc\ud398\ub2d0)-4H-1-\ubca4\uc870\ud53c\ub780-4-\uc628\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc73c\uba70, \ubd84\uc790\uc2dd\uc740 C\u2081\u2085H\u2081\u2080O\u2085\uc774\uace0 \ubd84\uc790\ub7c9\uc740 270.24\uc785\ub2c8\ub2e4. \uc81c\ub2c8\uc2a4\ud14c\uc778\uc758 \ubd84\uc790 \uad6c\uc870\ub294 \uc774\uc18c\ud50c\ub77c\ubcf4\ub178\uc774\ub4dc \uacc4\uc5f4 \ud654\ud569\ubb3c\uacfc \uc77c\uce58\ud558\uba70, \ud398\ub180\uc131 \uc218\uc0b0\uae30, \ud53c\ub860 \uace0\ub9ac, \ubca4\uc820 \uace0\ub9ac\ub85c \uad6c\uc131\ub41c \ub3c5\ud2b9\ud55c \ud654\ud559 \uad6c\uc870\ub97c \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uad6c\uc870\ub294 \uc81c\ub2c8\uc2a4\ud14c\uc778\uc774 \ud3f4\ub9ac\ud398\ub180\uc758 \uc804\ud615\uc801\uc778 \ub2e4\uc591\ud55c \ud654\ud559\uc801 \ud2b9\uc131\uc744 \ubd80\uc5ec\ud558\uc5ec \ud56d\uc0b0\ud654 \ud65c\uc131\uc744 \ub098\ud0c0\ub0bc \uc218 \uc788\ub3c4\ub85d \ud569\ub2c8\ub2e4. \uc218\uc18c \uc6d0\uc790\ub098 \uc804\uc790\ub97c \uc81c\uacf5\ud568\uc73c\ub85c\uc368, \uc81c\ub2c8\uc2a4\ud14c\uc778 \uc288\ud37c\uc625\uc0ac\uc774\ub4dc \uc74c\uc774\uc628 \ub77c\ub514\uce7c\uacfc \ud558\uc774\ub4dc\ub85d\uc2e4 \ub77c\ub514\uce7c\uacfc \uac19\uc740 \uccb4\ub0b4 … Continue reading \uc81c\ub2c8\uc2a4\ud14c\uc778\uff1a\ub2e4\uc7ac\ub2e4\ub2a5\ud55c \uc2dd\ubb3c\uc131 \uc5d0\uc2a4\ud2b8\ub85c\uac90\uacfc \uadf8 \uac74\uac15 \uc7a0\uc7ac\ub825<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":2824,"parent":0,"menu_order":32,"comment_status":"open","ping_status":"open","template":"","format":"standard","meta":{"footnotes":""},"class_list":["post-2823","blog","type-blog","status-publish","format-standard","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog\/2823","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog"}],"about":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/types\/blog"}],"author":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/comments?post=2823"}],"version-history":[{"count":0,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog\/2823\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/media\/2824"}],"wp:attachment":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/media?parent=2823"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}