{"id":2993,"date":"2025-11-20T02:46:01","date_gmt":"2025-11-20T02:46:01","guid":{"rendered":"https:\/\/www.focusherb.com\/kr\/?post_type=blog&p=2993"},"modified":"2025-11-20T02:46:01","modified_gmt":"2025-11-20T02:46:01","slug":"%ec%9a%b0%eb%a1%a4%eb%a6%ac%ed%8b%b4-a%ef%bc%9a%ec%9e%91%ec%9d%80-%eb%ac%bc%ec%a7%88%ec%9d%b4%ec%a7%80%eb%a7%8c-%eb%8b%a4%ec%96%91%ed%95%9c-%ec%9a%a9%eb%8f%84%eb%a1%9c-%ec%82%ac%ec%9a%a9-%ea%b0%80","status":"publish","type":"blog","link":"https:\/\/www.focusherb.com\/kr\/blog\/%ec%9a%b0%eb%a1%a4%eb%a6%ac%ed%8b%b4-a%ef%bc%9a%ec%9e%91%ec%9d%80-%eb%ac%bc%ec%a7%88%ec%9d%b4%ec%a7%80%eb%a7%8c-%eb%8b%a4%ec%96%91%ed%95%9c-%ec%9a%a9%eb%8f%84%eb%a1%9c-%ec%82%ac%ec%9a%a9-%ea%b0%80\/","title":{"rendered":"\uc6b0\ub864\ub9ac\ud2f4 A\uff1a\uc791\uc740 \ubb3c\uc9c8\uc774\uc9c0\ub9cc \ub2e4\uc591\ud55c \uc6a9\ub3c4\ub85c \uc0ac\uc6a9 \uac00\ub2a5"},"content":{"rendered":"

\uc0dd\uba85\uacfc\ud559\uacfc \uac74\uac15 \ubd84\uc57c\ub97c \ud0d0\uad6c\ud558\ub2e4 \ubcf4\uba74, \ucc98\uc74c\uc5d0\ub294 \ud2c8\uc0c8\uc2dc\uc7a5\uc73c\ub85c \uc5ec\uaca8\uc84c\uc9c0\ub9cc \uc2ec\uce35\uc801\uc778 \uc5f0\uad6c\ub97c \ud1b5\ud574 \ub180\ub78d\ub3c4\ub85d \uad11\ubc94\uc704\ud55c \uc751\uc6a9 \ubd84\uc57c\ub97c \ubc1d\ud600\ub0b8 \ubb3c\uc9c8\ub4e4\uc774 \ud56d\uc0c1 \uc874\uc7ac\ud569\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\uac00 \ubc14\ub85c \uadf8\ub7ec\ud55c \uc608\uc785\ub2c8\ub2e4. \uc774\ub984\uc740 \uc0dd\uc18c\ud560 \uc218 \uc788\uc9c0\ub9cc, \uc2e0\uc9c4\ub300\uc0ac \uac74\uac15 \uc720\uc9c0\ubd80\ud130 \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658 \ud1f4\uce58\uc5d0 \uc774\ub974\uae30\uae4c\uc9c0 \uc5ec\ub7ec \ud575\uc2ec \ubd84\uc57c\uc5d0\uc11c \uc870\uc6a9\ud788 \uc8fc\ubaa9\ubc1b\uace0 \uc788\uc73c\uba70, \uc2ec\uc9c0\uc5b4 \ubbf8\uc6a9 \ubc0f \uc2a4\ud0a8\ucf00\uc5b4 \ubd84\uc57c\uc5d0\uc11c\ub3c4 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc8fc\uba70 \uc5f0\uad6c\uc790\uc640 \uc5c5\uacc4\uc758 \uad00\uc2ec\uc744 \ub04c\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\uc758 \ub180\ub77c\uc6b4 \ud65c\uc6a9\ubc95\uc744 \uc790\uc138\ud788 \uc0b4\ud3b4\ubcf4\uaca0\uc2b5\ub2c8\ub2e4.\"\"<\/p>\n

\uc6b0\ub864\ub9ac\ud2f4 A\uc758 \uae30\uc6d0<\/h2>\n

(I) \uae30\uc6d0 \ubc0f \ucd9c\ucc98<\/h3>\n

\uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc790\uc5f0\uc5d0\uc11c \ub3c5\ub9bd\uc801\uc73c\ub85c \uc874\uc7ac\ud558\uc9c0 \uc54a\ub294 \ucc9c\uc5f0 \ud3f4\ub9ac\ud398\ub180 \ub300\uc0ac\uc0b0\ubb3c\uc785\ub2c8\ub2e4. \uadf8 \uc0dd\uc131 \uacfc\uc815\uc740 \ub9e4\uc6b0 \ub180\ub78d\uace0, \uc11d\ub958, \uacac\uacfc\ub958(\ud638\ub450 \ub4f1), \ub538\uae30, \ube14\ub799\ubca0\ub9ac\uc640 \uac19\uc740 \uce5c\uc219\ud55c \uc2dd\ud488\uc5d0\uc11c \uc720\ub798\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc2dd\ud488\uc5d0\ub294 \uc5d8\ub77c\uadf8\uc0b0\uacfc \uc5d8\ub77c\uae30\ud0c4\ub2cc\uc774 \ud48d\ubd80\ud569\ub2c8\ub2e4. \uc6b0\ub9ac\uac00 \uc774\ub7ec\ud55c \uc2dd\ud488\uc744 \uc12d\ucde8\ud558\uba74 \uc5d8\ub77c\uadf8\uc0b0\uacfc \uc5d8\ub77c\uae30\ud0c4\ub2cc\uc740 “\uc2e0\ube44\ub85c\uc6b4 \ucc98\ub9ac \uacf5\uc7a5”\uc778 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\ucd1d\uc758 \uc601\ud5a5\uc744 \ubc1b\uc544 \uc77c\ub828\uc758 \ubcf5\uc7a1\ud55c \ub300\uc0ac \uacfc\uc815\uc744 \uac70\uccd0 \uad81\uadf9\uc801\uc73c\ub85c \uc6b0\ub864\ub9ac\ud2f4 A\ub97c \uc0dd\uc131\ud569\ub2c8\ub2e4. \uc989, \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\ucd1d\uc758 \uc885\ub958\uc640 \uc591\uc740 \uc6b0\ub864\ub9ac\ud2f4 A \uc0dd\uc131\uc758 \ud6a8\uc728\uacfc \uc591\uc5d0 \uc0c1\ub2f9\ud55c \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\ucd1d\uc758 \ucc28\uc774\ub85c \uc778\ud574, \uc5d8\ub77c\uadf8\uc0b0\uc774 \ud48d\ubd80\ud55c \ub3d9\uc77c\ud55c \uc2dd\ud488\uc744 \uc12d\ucde8\ud558\ub354\ub77c\ub3c4 \uccb4\ub0b4\uc5d0\uc11c \uc0dd\uc131\ub418\ub294 \uc6b0\ub864\ub9ac\ud2f4 A\uc758 \uc218\uce58\ub294 \uac1c\uc778\ub9c8\ub2e4 \ub2e4\ub985\ub2c8\ub2e4.<\/p>\n

(II) \ud654\ud559\uc801 \ubc0f \ubb3c\ub9ac\uc801 \ud2b9\uc131<\/h3>\n

\ud654\ud559 \uad6c\uc870\uc801 \uad00\uc810\uc5d0\uc11c, \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ubd84\uc790\uc2dd C13H8O4\ub97c \uac00\uc9c0\uba70 \ubd84\uc790\ub7c9\uc740 228.2\uc785\ub2c8\ub2e4. \uc774 \uad6c\uc870\ub294 3\ubc88\uacfc 8\ubc88 \uc704\uce58\uc5d0 \ud788\ub4dc\ub85d\uc2dc\uae30\uac00 \uacb0\ud569\ub41c \ub3c5\ud2b9\ud55c \ub514\ubca4\uc870\ud53c\ub77c\ub17c \uace8\uaca9\uc744 \ud3ec\ud568\ud569\ub2c8\ub2e4. \uc774 \ud2b9\ubcc4\ud55c \ud654\ud559 \uad6c\uc870\ub294 \uc5ec\ub7ec \uac00\uc9c0 \ub3c5\ud2b9\ud55c \ud654\ud559\uc801 \ud2b9\uc131\uc744 \ubd80\uc5ec\ud569\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \ud398\ub180\uc131 \ud788\ub4dc\ub85d\uc2dc\uae30\ub294 \uc77c\uc815 \uc218\uc900\uc758 \uc0b0\uc131\ub3c4\ub97c \ubd80\uc5ec\ud558\uc5ec \uc77c\ubd80 \uc0b0-\uc5fc\uae30 \ubc18\uc751\uc5d0 \ucc38\uc5ec\ud560 \uc218 \uc788\ub3c4\ub85d \ud569\ub2c8\ub2e4. \ubb3c\ub9ac\uc801 \ud2b9\uc131 \uce21\uba74\uc5d0\uc11c, \uc2e4\uc628 \ubc0f \uc0c1\uc555\uc5d0\uc11c \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ud770\uc0c9\uc5d0\uc11c \uc5f0\ub178\ub780\uc0c9 \ubd84\ub9d0\uc774\uba70, \uc774\ub294 \uc6b0\ub9ac\uac00 \uac00\uc7a5 \ud754\ud788 \ubcfc \uc218 \uc788\ub294 \ud615\ud0dc\uc785\ub2c8\ub2e4. \ub179\ub294\uc810\uc740 340~345\u00b0C\uc774\uba70, \uc774 \uc628\ub3c4\uc5d0\uc11c \uace0\uccb4\uc5d0\uc11c \uc561\uccb4\ub85c \ubcc0\ud569\ub2c8\ub2e4. \uc6a9\ud574\ub3c4 \uce21\uba74\uc5d0\uc11c\ub294 \ubb3c\uc5d0 \uc57d\uac04 \uc6a9\ud574\ub418\uc5b4 \ubb3c\uc5d0 \ub300\ud55c \ubd84\uc0b0\uc131\uc774 \ub0ae\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ub514\uba54\ud2f8 \uc124\ud3ed\uc0ac\uc774\ub4dc \ubc0f N,N-\ub514\uba54\ud2f8\ud3ec\ub984\uc544\ubbf8\ub4dc\uc640 \uac19\uc740 \uadf9\uc131\uc774 \ub192\uc740 \uc720\uae30 \uc6a9\ub9e4\uc5d0\ub294 \uc798 \ub179\ub294 \ubc18\uba74, \uadf9\uc131\uc774 \ub0ae\uc740 \uc11d\uc720 \uc5d0\ud14c\ub974 \ubc0f \ub514\uc5d0\ud2f8 \uc5d0\ud14c\ub974\uc5d0\ub294 \uc6a9\ud574\ub3c4\uac00 \ub0ae\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc758\ud559 \ubd84\uc57c\uc758 \ub2e4\uc7ac\ub2e4\ub2a5\ud55c \uc81c\uc81c<\/h2>\n

\uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc758\ud559 \ubd84\uc57c\uc5d0\uc11c \ub208\ubd80\uc2e0 \uc5f0\uad6c \uc131\uacfc\ub97c \uac70\ub450\uba70 \ub2e4\uc591\ud55c \uc9c8\ubcd1 \uadf9\ubcf5\uc5d0 \ub300\ud55c \ud76c\ub9dd\uc758 \ube5b\uc744 \ube44\ucd94\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

(I) \uc2ec\ud608\uad00 \uc9c8\ud658\uc758 \uc0c8\ub85c\uc6b4 \ud76c\ub9dd<\/h3>\n

\uc2ec\ud608\uad00 \uc9c8\ud658\uc740 \ud56d\uc0c1 \uc778\ub958 \uac74\uac15\uc744 \uc704\ud611\ud558\ub294 “1\uc704 \uc0ac\ub9dd \uc6d0\uc778”\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \uad00\uc0c1\ub3d9\ub9e5 \uc2ec\uc7a5 \uc9c8\ud658\uc774\ub098 \uc2ec\uadfc\uacbd\uc0c9\uacfc \uac19\uc740 \ud5c8\ud608\uc131 \uc2ec\uc7a5 \uc9c8\ud658\uc740 \ub9e4\ub144 \uc218\ub9ce\uc740 \ud658\uc790\ub4e4\uc758 \uc0dd\uba85\uc744 \uc557\uc544\uac00\uac70\ub098 \uc0b6\uc758 \uc9c8\uc744 \uc2ec\uac01\ud558\uac8c \uc800\ud558\uc2dc\ud0b5\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc2ec\ud608\uad00 \uc9c8\ud658 \uce58\ub8cc\uc5d0 \ub3c5\ubcf4\uc801\uc778 \uc7a0\uc7ac\ub825\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ud608\uad00\uc2e0\uc0dd\uc744 \ucd09\uc9c4\ud558\uc5ec \uc0c8\ub85c\uc6b4 \ud608\uad00\uc758 \uc131\uc7a5\uc744 \ucd09\uc9c4\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uad00\uc0c1\ub3d9\ub9e5 \uc2ec\uc7a5 \uc9c8\ud658 \ud658\uc790\uc758 \uacbd\uc6b0, \uc8fd\uc0c1\ub3d9\ub9e5\uacbd\ud654\uc99d \ub4f1\uc758 \uc774\uc720\ub85c \uad00\uc0c1\ub3d9\ub9e5\uc774 \uc881\uc544\uc9c0\uac70\ub098 \ub9c9\ud600 \uc2ec\uadfc\uc758 \ud608\uc561 \uacf5\uae09\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc2ec\uadfc \ud608\uc561 \uacf5\uae09\uc744 \uc704\ud55c “\ubc31\uc5c5 \ucc44\ub110”\uc744 \uc5f4\uc5b4 \uc2ec\uadfc \ud608\uc561 \uacf5\uae09\uc744 \uac1c\uc120\ud558\ub294 \uac83\ucc98\ub7fc \uad00\uc0c1\ub3d9\ub9e5 \uce21\ubd80 \uc21c\ud658 \ud615\uc131\uc744 \ucd09\uc9c4\ud558\uc5ec \uc9c8\ud658\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uc644\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub3d9\uc2dc\uc5d0 \ud608\uc561 \uc21c\ud658\uc744 \uac1c\uc120\ud558\uc5ec \ud608\uad00 \ub0b4 \ud608\uc561 \ud750\ub984\uc744 \uc6d0\ud65c\ud558\uac8c \ud558\uace0, \uc5fc\uc99d \ubc18\uc751\uc744 \uac10\uc18c\uc2dc\ucf1c \ud608\uad00\ubcbd\uc758 \uc5fc\uc99d \uc190\uc0c1\uc744 \uc904\uc785\ub2c8\ub2e4. \ub2e4\ubc29\uba74\uc5d0\uc11c \uc2ec\ud608\uad00 \uac74\uac15\uc744 \ubcf4\ud638\ud558\uace0 \uc2ec\ud608\uad00 \uc9c8\ud658 \uce58\ub8cc\uc5d0 \uc0c8\ub85c\uc6b4 \uc804\ub7b5\uc744 \uc81c\uc2dc\ud569\ub2c8\ub2e4.<\/p>\n

(II) \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658\uc5d0 \ub300\ud55c \ud76c\ub9dd\uc758 \ube5b<\/h3>\n

\uc804 \uc138\uacc4\uc801\uc73c\ub85c \uace0\ub839\ud654\uac00 \uc2ec\ud654\ub428\uc5d0 \ub530\ub77c \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc774\ub098 \ud30c\ud0a8\uc2a8\ubcd1\uacfc \uac19\uc740 \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658\uc758 \ubc1c\ubcd1\ub960\uc774 \uc9c0\uc18d\uc801\uc73c\ub85c \uc99d\uac00\ud558\uc5ec \ud658\uc790 \uac00\uc871\uacfc \uc0ac\ud68c\uc5d0 \ud070 \ubd80\ub2f4\uc744 \uc8fc\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \ubd84\uc57c\uc5d0\uc11c \uc6b0\ub864\ub9ac\ud2f4 A \uc5f0\uad6c\uc758 \ubc1c\uc804\uc740 \ud658\uc790\ub4e4\uc5d0\uac8c \uc0c8\ub85c\uc6b4 \ud76c\ub9dd\uc744 \uac00\uc838\ub2e4\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4. \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 \uc138\ud3ec\uc758 “\uc5d0\ub108\uc9c0 \uacf5\uc7a5”\uc774\uba70, \ubbf8\ud1a0\ud30c\uc9c0\ub294 \uc190\uc0c1\ub418\uac70\ub098 \uacfc\ub3c4\ud55c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub97c \uc81c\uac70\ud558\uace0 \uc815\uc0c1\uc801\uc778 \uc138\ud3ec \uae30\ub2a5\uc744 \uc720\uc9c0\ud558\ub294 \ub370 \ub9e4\uc6b0 \uc911\uc694\ud569\ub2c8\ub2e4. \uc774 \uae30\ub2a5\uc758 \uc190\uc0c1\uc740 \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658\uc758 \ubc1c\uc0dd \ubc0f \ubc1c\ubcd1\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \ub374\ub9c8\ud06c \ucf54\ud39c\ud558\uac90 \ub300\ud559\uad50\uc640 \uac19\uc740 \uc5f0\uad6c \uae30\uad00\uc758 \uc5f0\uad6c\uc9c4\uc740 \ub9c8\uc6b0\uc2a4 \uc2e4\ud5d8\uc744 \ud1b5\ud574 \uc6b0\ub864\ub9ac\ud2f4 A\uac00 \ubbf8\ud1a0\ud30c\uc9c0\ub97c \uc790\uadf9\ud560 \uc218 \uc788\uc74c\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \uc2e4\ud5d8\uc6a9 \ub9c8\uc6b0\uc2a4\uc5d0 \uc6b0\ub864\ub9ac\ud2f4 A\ub97c \uc7a5\uae30\uac04 \ud22c\uc5ec\ud55c \uacb0\uacfc, \ud559\uc2b5, \uae30\uc5b5, \ud6c4\uac01 \uae30\ub2a5\uc774 \uc720\uc758\ubbf8\ud558\uac8c \ud5a5\uc0c1\ub418\uc5c8\uace0, \ubca0\ud0c0 \uc544\ubc00\ub85c\uc774\ub4dc \ub2e8\ubc31\uc9c8\uc758 \ube44\uc815\uc0c1\uc801\uc778 \ucd95\uc801 \ubc0f \ud0c0\uc6b0 \ub2e8\ubc31\uc9c8\uc758 \uacfc\uc778\uc0b0\ud654\uc640 \uac19\uc740 \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc758 \uc8fc\uc694 \ubcd1\ub9ac\ud559\uc801 \ud2b9\uc9d5\uc774 \uac10\uc18c\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc6b0\ub864\ub9ac\ud2f4 A\uac00 \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658\uc758 \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \ud070 \uc7a0\uc7ac\ub825\uc744 \uac00\uc9c0\uace0 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.<\/p>\n

(III) \uac15\ub825\ud55c \ud56d\uc5fc\uc99d \ubb34\uae30<\/h3>\n

\uc778\uccb4\uc5d0\uc11c \uc5fc\uc99d\uc740 \ub2e4\uc591\ud55c \uc790\uadf9\uc5d0 \ub300\ud55c \ubc29\uc5b4 \uae30\uc81c\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc5fc\uc99d\uc774 \ud1b5\uc81c \ubd88\ub2a5\uc774 \ub418\uba74 \uad00\uc808\uc5fc\uc774\ub098 \uc7a5\uc5fc\uacfc \uac19\uc740 \uc77c\ub828\uc758 \uac74\uac15 \ubb38\uc81c\ub97c \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uac15\ub825\ud55c \ud56d\uc5fc\uc99d \ud65c\uc131\uc744 \uac00\uc9c4 “\ud56d\uc5fc\uc99d \uc218\ud638\uc790”\ucc98\ub7fc \uc791\uc6a9\ud569\ub2c8\ub2e4. \uc885\uc591\uad34\uc0ac\uc778\uc790-\u03b1(TNF-\u03b1) \ubc0f \uc778\ud130\ub8e8\ud0a8-6(IL-6)\uc640 \uac19\uc740 \ub2e4\uc591\ud55c \uc5fc\uc99d \ub9e4\uac1c\uccb4\uc758 \uc0dd\uc131\uc744 \uc5b5\uc81c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc5fc\uc99d \ub9e4\uac1c\uccb4\ub294 \uc5fc\uc99d \ubc18\uc751\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\uba70, \uacfc\ub3c4\ud55c \ubc29\ucd9c\uc740 \uc5fc\uc99d\uc744 \uc545\ud654\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc774\ub7ec\ud55c \uc0dd\uc131\uc744 \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc5fc\uc99d \ubc18\uc751\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uac10\uc18c\uc2dc\ud0a4\uace0 \ud56d\uc5fc\uc99d\uc81c \uac1c\ubc1c\uc5d0 \ud070 \uc7a0\uc7ac\ub825\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc544\ub9c8\ub3c4 \ubbf8\ub798\uc5d0\ub294 \ub2e4\uc591\ud55c \uc5fc\uc99d\uc131 \uc9c8\ud658 \uce58\ub8cc\uc5d0 \uc911\uc694\ud55c \uc131\ubd84\uc774 \ub420 \uc218 \uc788\uc744 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

(IV) \ud56d\ub178\ud654 \ubc0f \uba74\uc5ed \uc870\uc808\uc758 \uc120\uad6c\uc790<\/h3>\n

\ub178\ud654\ub294 \ud53c\ud560 \uc218 \uc5c6\ub294 \uc790\uc5f0\uc2a4\ub7ec\uc6b4 \uacfc\uc815\uc774\uc9c0\ub9cc, \uc6b0\ub864\ub9ac\ud2f4 A\uc758 \ucd9c\ud604\uc740 \ub178\ud654\ub97c \ub2a6\ucd94\ub294 \uc804\ud658\uc810\uc744 \uc81c\uacf5\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ud154\ub85c\uba38\ub77c\uc81c \ud65c\uc131\uc744 \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc138\ud3ec \ub178\ud654 \uacfc\uc815\uc744 \uc9c0\uc5f0\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud154\ub85c\uba38\ub77c\uc81c\ub294 \uc138\ud3ec \uc218\uba85\uacfc \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\uc73c\uba70, \ud154\ub85c\uba38\ub77c\uc81c \ud65c\uc131\uc744 \uc5b5\uc81c\ud558\uba74 \uc138\ud3ec \ub178\ud654 \uc18d\ub3c4\ub97c \ub2a6\ucd9c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub3d9\uc2dc\uc5d0 \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5\uc744 \ucd09\uc9c4\ud560 \uc218\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \uc138\ud3ec\uc758 \uc5d0\ub108\uc9c0 \ub300\uc0ac \uc911\uc2ec\uc778 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5 \ud5a5\uc0c1\uc740 \uc138\ud3ec\uc758 \uc5d0\ub108\uc9c0 \ub300\uc0ac \uc218\uc900\uc744 \ub192\uc774\uace0 \uc815\uc0c1\uc801\uc778 \uc138\ud3ec \uae30\ub2a5\uc744 \uc720\uc9c0\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub429\ub2c8\ub2e4. \ub610\ud55c, \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uba74\uc5ed \uc870\uc808\uc5d0\ub3c4 \uae0d\uc815\uc801\uc778 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc2e0\uccb4\uc758 \uba74\uc5ed\ub825\uacfc \uc800\ud56d\ub825\uc744 \ud5a5\uc0c1\uc2dc\ucf1c \ubcd1\uc6d0\uade0\uc758 \uce68\uc785\uc5d0 \ub300\ud55c \uc800\ud56d\ub825\uc744 \uac15\ud654\ud558\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc90d\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ub178\ud654 \ubc29\uc9c0 \uc57d\ubb3c \ubc0f \uba74\uc5ed \uc870\uc808\uc81c \uac1c\ubc1c\uc5d0 \uc788\uc5b4 \ud3ed\ub113\uc740 \uc751\uc6a9 \uac00\ub2a5\uc131\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.\"\"<\/p>\n

\uac74\uac15 \ubcf4\uc870 \uc2dd\ud488\uc758 “\uc8fc\uc694 \uc131\ubd84”<\/h2>\n

\uac74\uac15\uacfc \uc9c8 \ub192\uc740 \uc0b6\uc744 \ucd94\uad6c\ud558\ub294 \uc624\ub298\ub0a0, \ub208\ubd80\uc2e0 \ub2e4\uc591\ud55c \uc131\ubd84\uc744 \uac16\ucd98 \uac74\uac15 \ubcf4\uc870\uc81c \uc2dc\uc7a5\uc774 \uae09\uc131\uc7a5\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud2b9\ud788 \ub6f0\uc5b4\ub09c \ud6a8\ub2a5\uc744 \uc790\ub791\ud558\ub294 A\ud615 \uc694\ub85c\uacb0\uc11d\uc99d\uc740 \uac74\uac15 \ubcf4\uc870\uc81c \ubd84\uc57c\uc758 \ud575\uc2ec “\uc2a4\ud0c0 \uc131\ubd84”\uc73c\ub85c \uc810\ucc28 \ubd80\uc0c1\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

(I) \ud56d\uc0b0\ud654 “\uc120\ubd09”
\n\uc6b0\ub9ac \ubab8\uc5d0\uc11c \ud65c\uc131\uc0b0\uc18c\ub294 \ub9c8\uce58 \uc7a5\ub09c\uafb8\ub7ec\uae30 “\uad34\ubb3c”\ucc98\ub7fc \ub04a\uc784\uc5c6\uc774 \uc138\ud3ec\ub97c \uacf5\uaca9\ud558\uace0 \uc0b0\ud654\uc801 \uc190\uc0c1\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4. \uc138\ud3ec \uc218\uc900\uc5d0\uc11c \ud65c\uc131\uc0b0\uc18c\ub294 \uc138\ud3ec\ub9c9 \uad6c\uc870\ub97c \uc190\uc0c1\uc2dc\ucf1c \ud22c\uacfc\uc131\uc744 \ubcc0\ud654\uc2dc\ud0a4\uace0 \uc138\ud3ec \ub0b4\uc678\ubd80 \uac04\uc758 \uc815\uc0c1\uc801\uc778 \ubb3c\uc9c8 \uad50\ud658\uc744 \ubc29\ud574\ud558\uc5ec \uc815\uc0c1\uc801\uc778 \uc138\ud3ec \uc0dd\ub9ac \uae30\ub2a5\uc744 \ubc29\ud574\ud569\ub2c8\ub2e4. \ub610\ud55c \uc138\ud3ec \ub0b4 \ub2e8\ubc31\uc9c8\uc744 \uacf5\uaca9\ud558\uc5ec \uad6c\uc870\uc640 \uae30\ub2a5\uc744 \ubcc0\ud654\uc2dc\ud0a4\uace0, \uc5ec\ub7ec \uc911\uc694 \ud6a8\uc18c\uc758 \ud65c\uc131\uc744 \uc800\ud558\uc2dc\ud0a4\uba70 \uc138\ud3ec \ub300\uc0ac \uacfc\uc815\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uc870\uc9c1 \uc218\uc900\uc5d0\uc11c \uc0b0\ud654\uc801 \uc190\uc0c1\uc740 \uac74\ubb3c\uc758 \ucca0\uadfc\uacfc \uc2dc\uba58\ud2b8\uac00 \ud30c\uad34\ub418\ub294 \uac83\ucc98\ub7fc \ucf5c\ub77c\uac90\uacfc \uc5d8\ub77c\uc2a4\ud2f4 \uc12c\uc720\ub97c \uc190\uc0c1\uc2dc\ucf1c \ud53c\ubd80 \ud0c4\ub825 \uac10\uc18c, \uc8fc\ub984, \ucc98\uc9d0, \uae30\ud0c0 \ub178\ud654 \uc9d5\ud6c4\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4. \ub610\ud55c \uc7a5\uae30 \ub178\ud654\ub97c \ucd09\uc9c4\ud558\uace0 \ub9cc\uc131 \uc9c8\ud658\uc758 \uc704\ud5d8\uc744 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uac15\ub825\ud55c \ud56d\uc0b0\ud654 \ub2a5\ub825\uc744 \uc9c0\ub2cc “\ud56d\uc0b0\ud654 \uc120\ubd09\uc790” \uc5ed\ud560\uc744 \ud558\uba70, \uccb4\ub0b4 \ud65c\uc131\uc0b0\uc18c\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \uc81c\uac70\ud558\uace0 \uc0b0\ud654\uc801 \uc190\uc0c1\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \uad00\ub828 \uc2e4\ud5d8\uc5d0 \ub530\ub974\uba74, \uc2dc\ud5d8\uad00 \ub0b4 \uc138\ud3ec \uc2e4\ud5d8\uc5d0\uc11c \uc6b0\ub864\ub9ac\ud2f4 A\ub97c \ucca8\uac00\ud588\uc744 \ub54c \uc138\ud3ec \ub0b4 \ud65c\uc131\uc0b0\uc18c \uc218\uce58\uac00 \ud604\uc800\ud788 \uac10\uc18c\ud558\uace0 \uc138\ud3ec \ud65c\uc131\uacfc \uc0dd\uc874\uc728\uc774 \ud604\uc800\ud788 \ud5a5\uc0c1\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub3d9\ubb3c \uc2e4\ud5d8\uc5d0\uc11c \ub178\ud654 \ubaa8\ub378 \ub3d9\ubb3c\uc5d0\uac8c \uc6b0\ub864\ub9ac\ud2f4 A\ub97c \uc77c\uc815 \uae30\uac04 \ub3d9\uc548 \ud22c\uc5ec\ud588\uc744 \ub54c \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \uc9c0\ud45c\uac00 \ud604\uc800\ud788 \uac1c\uc120\ub418\uc5c8\uace0, \ud53c\ubd80 \ud0c4\ub825\uacfc \uc724\uae30\uac00 \ud5a5\uc0c1\ub418\uc5b4 \ud56d\uc0b0\ud654, \ub178\ud654 \uc608\ubc29, \ub9cc\uc131 \uc9c8\ud658 \uad00\ub9ac\uc5d0 \uc788\uc5b4 \uc6b0\ub864\ub9ac\ud2f4 A\uc758 \ud0c1\uc6d4\ud55c \ud6a8\ub2a5\uc744 \ucda9\ubd84\ud788 \uc785\uc99d\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

(II) \uccb4\uc911 \uad00\ub9ac “\ubcf4\uc870”
\n\ube44\ub9cc\uc740 \uc678\ubaa8\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \ubfd0\ub9cc \uc544\ub2c8\ub77c \uc2ec\ud608\uad00 \uc9c8\ud658, \ub2f9\ub1e8\ubcd1\uacfc \uac19\uc740 \ube44\ub9cc\uacfc \ubc00\uc811\ud55c \uad00\ub828\uc774 \uc788\ub294 \uc5ec\ub7ec \uac74\uac15 \ubb38\uc81c\uc758 \uc6d0\uc778\uc774 \ub429\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uccb4\uc911 \uad00\ub9ac\uc5d0 \uc788\uc5b4 \ub3c5\ud2b9\ud55c \uc791\uc6a9 \uae30\uc804\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc778\uccb4\uc5d0\ub294 \uac08\uc0c9 \uc9c0\ubc29 \uc870\uc9c1\uacfc \ubc31\uc0c9 \uc9c0\ubc29 \uc870\uc9c1\uc774\ub77c\ub294 \ub450 \uac00\uc9c0 \uc911\uc694\ud55c \uc720\ud615\uc758 \uc9c0\ubc29 \uc870\uc9c1\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uac08\uc0c9 \uc9c0\ubc29 \uc870\uc9c1\uc740 “\ubc1c\uc5f4 \ubaa8\ud130”\ucc98\ub7fc \uc791\uc6a9\ud558\uc5ec \uc8fc\ub85c \uc9c0\ubc29\uc744 \uc5d0\ub108\uc9c0\ub85c \uc804\ud658\ud558\uc5ec \uc5f4\uc744 \ubc1c\uc0dd\uc2dc\ucf1c \uccb4\ub0b4 \uc9c0\ubc29 \ucd95\uc801\uc744 \uc904\uc774\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc90d\ub2c8\ub2e4. \ubc18\uba74 \ubc31\uc0c9 \uc9c0\ubc29 \uc870\uc9c1\uc740 \uc8fc\ub85c \uc9c0\ubc29\uc744 \uc800\uc7a5\ud558\ub294 \uc5ed\ud560\uc744 \ud558\uba70, \ubc31\uc0c9 \uc9c0\ubc29 \uc870\uc9c1\uc758 \uacfc\ub3c4\ud55c \ucd95\uc801\uc740 \ube44\ub9cc\uc73c\ub85c \uc774\uc5b4\uc9d1\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc9c0\ubc29 \ub0b4 \ud2b8\ub9ac\uc694\uc624\ub4dc\ud2f0\ub85c\ub2cc(T3) \uc218\uce58\ub97c \uc99d\uac00\uc2dc\ucf1c \uac08\uc0c9 \uc9c0\ubc29 \uc870\uc9c1\uc758 \uc5f4 \uc0dd\uc131\uc744 \ucd09\uc9c4\ud558\uace0, \uc774 “\ubaa8\ud130”\ub97c \ub354 \uc790\uc8fc \uc791\ub3d9\uc2dc\ucf1c \uc9c0\ubc29 \uc5f0\uc18c\ub97c \uac00\uc18d\ud654\ud569\ub2c8\ub2e4. \ub3d9\uc2dc\uc5d0 \ubc31\uc0c9 \uc9c0\ubc29 \uc870\uc9c1\uc758 \uac08\ubcc0\uc744 \uc720\ub3c4\ud558\uc5ec \uc6d0\ub798 \uc9c0\ubc29\uc744 \uc800\uc7a5\ud558\ub358 \ubc31\uc0c9 \uc9c0\ubc29 \uc138\ud3ec\ub97c \uc5f4 \uc0dd\uc131 \uae30\ub2a5\uc744 \uac00\uc9c4 \uac08\uc0c9 \uc9c0\ubc29 \uc138\ud3ec\ub85c \uc804\ud658\uc2dc\ucf1c \uc5d0\ub108\uc9c0 \uc18c\ube44\ub97c \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4. \uace0\uc9c0\ubc29 \uc2dd\uc774\ub97c \uc12d\ucde8\ud55c \uc950\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \uc2e4\ud5d8\uc5d0\uc11c, \uc6b0\ub864\ub9ac\ud2f4 A\ub97c 2\uc8fc \ub3d9\uc548 \ubcf4\ucda9\ud55c \ud6c4 \uc950\uc758 \uccb4\uc911\uacfc \uc9c0\ubc29\ub7c9\uc740 \ub300\uc870\uad70\ubcf4\ub2e4 \uac01\uac01 23.5%\uc640 61.3% \uac10\uc18c\ud588\uc73c\uba70, \uccb4\uc9c0\ubc29\ub960\uc740 \ub300\uc870\uad70\uc758 3\ubd84\uc758 1 \ubbf8\ub9cc\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uccb4\uc911 \uac10\ub7c9\uacfc \uc2e0\uc9c4\ub300\uc0ac \uae30\ub2a5 \ud5a5\uc0c1\uc5d0 \uc788\uc5b4 \uc6b0\ub864\ub9ac\ud2f4 A\uc758 \uc720\uc758\ubbf8\ud55c \ud6a8\uacfc\ub97c \ucda9\ubd84\ud788 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.<\/p>\n

(III) \uadfc\uc721 \uac74\uac15 “\uc218\ud638\uc790”
\n\uadfc\uc721\uc740 \uc6b0\ub9ac \ubab8\uc758 \uc6c0\uc9c1\uc784\uacfc \uadfc\ub825\uc758 \uc6d0\ucc9c\uc785\ub2c8\ub2e4. \ub098\uc774\uac00 \ub4e4\uace0, \uc2e0\uccb4 \ud65c\ub3d9\uc774 \uac10\uc18c\ud558\uace0, \uc9c8\ubcd1\uc758 \uc601\ud5a5\uc744 \ubc1b\uc73c\uba74 \uadfc\uc721\uc740 \uc810\ucc28 \uc704\ucd95\ub418\uace0 \uadfc\ub825\uc744 \uc783\uc2b5\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uadfc\uc721 \uac74\uac15 \uc720\uc9c0\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc0dd\ub9ac\ud559\uc801 \uad00\uc810\uc5d0\uc11c, \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ub2e4\uc591\ud55c \uacbd\ub85c\ub97c \ud1b5\ud574 \uadfc\uc721 \uac74\uac15\uc744 \uc99d\uc9c4\uc2dc\ud0b5\ub2c8\ub2e4. \uac15\ub825\ud55c \ud56d\uc0b0\ud654\uc81c\uc778 \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uccb4\ub0b4\uc758 \ud65c\uc131\uc0b0\uc18c\ub97c \uc81c\uac70\ud558\uc5ec \uadfc\uc721 \uc138\ud3ec\uc758 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \uc190\uc0c1\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uccb4\ub0b4 \ub9d0\ub860\ub514\uc54c\ub370\ud788\ub4dc(MDA)\uc640 \uacfc\uc0b0\ud654\uc218\uc18c(H\u2082O\u2082) \uc218\uce58\ub97c \ud604\uc800\ud788 \uac10\uc18c\uc2dc\ud0a4\ub294 \ub3d9\uc2dc\uc5d0 \uc288\ud37c\uc625\uc0ac\uc774\ub4dc \ub514\uc2a4\ubba4\ud0c0\uc544\uc81c(SOD)\uc640 \uae00\ub8e8\ud0c0\ud2f0\uc628 \ud37c\uc625\uc2dc\ub2e4\uc544\uc81c(GSH-Px)\uc758 \ud65c\uc131\uc744 \uc99d\uac00\uc2dc\ucf1c \uc0b0\ud654 \uc190\uc0c1\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uac10\uc18c\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ub610\ud55c, \ud575\uc778\uc790 \u03baB(NF-\u03baB)\uc758 \ud65c\uc131\uc744 \uc5b5\uc81c\ud558\uc5ec \uc5fc\uc99d \uc778\uc790 \uc0dd\uc131\uc744 \uac10\uc18c\uc2dc\ud0a4\ub294 \ub4f1 \uc0c1\ub2f9\ud55c \ud56d\uc5fc\uc99d \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0b4\uba70, \uc774\ub97c \ud1b5\ud574 \uadfc\uc721 \uc870\uc9c1\uc758 \uc5fc\uc99d \ubc18\uc751 \uc190\uc0c1\uc744 \uc644\ud654\ud569\ub2c8\ub2e4. \uc774 \uae30\uc804\uc740 \uc5fc\uc99d\uc73c\ub85c \uc778\ud55c \uadfc\uc721 \uc9c8\ud658\uc758 \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \ud2b9\ud788 \uc911\uc694\ud569\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ub610\ud55c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5\uc744 \ucd09\uc9c4\ud558\uace0 \uc138\ud3ec \uc5d0\ub108\uc9c0 \ub300\uc0ac\ub97c \uac1c\uc120\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 \uc138\ud3ec\uc758 “\uc5d0\ub108\uc9c0 \uacf5\uc7a5”\uc774\uba70, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc758 \uc815\uc0c1\uc801\uc778 \uae30\ub2a5\uc740 \uadfc\uc721 \uc138\ud3ec\uc758 \uac74\uac15\uacfc \ud65c\ub825\uc5d0 \uc9c1\uc811\uc801\uc778 \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ubbf8\ud1a0\ud30c\uc9c0 \uc720\ub3c4, \uc190\uc0c1\ub41c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc81c\uac70, \uc0c8\ub85c\uc6b4 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc0dd\uc131 \ucd09\uc9c4\uc744 \ud1b5\ud574 \uadfc\uc721 \uc138\ud3ec\uc758 \uc5d0\ub108\uc9c0 \uacf5\uae09 \ubc0f \ub300\uc0ac \uade0\ud615\uc744 \uc720\uc9c0\ud569\ub2c8\ub2e4. \uc2e4\uc81c \uc801\uc6a9 \ubd84\uc57c\uc5d0\uc11c\ub294 \uc6b0\ub864\ub9ac\ud2f4 A\uac00 \uadfc\uc721 \uac74\uac15\uc5d0 \ubbf8\uce58\ub294 \uae0d\uc815\uc801\uc778 \ud6a8\uacfc\ub97c \ub4b7\ubc1b\uce68\ud558\ub294 \ub9ce\uc740 \uc2e4\ud5d8 \ub370\uc774\ud130\uac00 \uc788\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4 \uc2a4\uc704\uc2a4 \uacfc\ud559\uc790\ub4e4\uc774 2022\ub144 *Cell Reports Medicine*\uc5d0 \ubc1c\ud45c\ud55c \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74, \uc6b0\ub864\ub9ac\ud2f4 A\ub97c 4\uac1c\uc6d4 \ub3d9\uc548 \uc9c0\uc18d\uc801\uc73c\ub85c \uc0ac\uc6a9\ud55c \uc911\ub144\uce35\uc758 \uadfc\ub825\uc774 12% \uc720\uc758\ubbf8\ud558\uac8c \uc99d\uac00\ud588\uc2b5\ub2c8\ub2e4. \ud608\uc561 \uac80\uc0ac\uc640 \uace8\uaca9\uadfc \uc0dd\uac80 \uacb0\uacfc, \uac74\uac15\ud55c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5\uc744 \ub098\ud0c0\ub0b4\ub294 \ubc14\uc774\uc624\ub9c8\ucee4\uac00 \uc720\uc758\ubbf8\ud558\uac8c \uac1c\uc120\ub418\uc5c8\uace0 \uc5fc\uc99d\uc774 \uac10\uc18c\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc6b0\ub864\ub9ac\ud2f4 A\uac00 \uadfc\uc704\ucd95 \uc608\ubc29, \uc6b4\ub3d9 \ub2a5\ub825 \ud5a5\uc0c1, \uadfc\uc721 \uc9c8\ud658 \uce58\ub8cc, \uadf8\ub9ac\uace0 \uadfc\uc721 \ud68c\ubcf5 \ucd09\uc9c4\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\uba70, \uadfc\uc721 \uac74\uac15\uc758 “\uc218\ud638\uc790”\ub85c\uc11c \ub9c8\ub545\ud788 \uc778\uc815\ubc1b\uc544\uc57c \ud560 \uc874\uc7ac\uc784\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.<\/p>\n

\"\"\ud654\uc7a5\ud488 \uc5c5\uacc4\uc758 \ub5a0\uc624\ub974\ub294 \uc2e0\uc131<\/h2>\n

\ud654\uc7a5\ud488 \uc5c5\uacc4\uc5d0\uc11c \ud56d\ub178\ud654, \uc7ac\uc0dd, \ubcf4\uc2b5 \uc81c\ud488\uc5d0 \ub300\ud55c \uc18c\ube44\uc790 \uc218\uc694\ub294 \uafb8\uc900\ud788 \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ub3c5\ud2b9\ud55c \uc0dd\ubb3c\ud559\uc801 \ud2b9\uc131\uc744 \uc9c0\ub2cc \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc774\ub7ec\ud55c \ud575\uc2ec \uc601\uc5ed\uc5d0\uc11c \ud0c1\uc6d4\ud55c \ud6a8\ub2a5\uc744 \uc785\uc99d\ud558\uba70 \ud56d\ub178\ud654 \ud654\uc7a5\ud488 \uc5c5\uacc4\uc758 \ub5a0\uc624\ub974\ub294 \uc2e0\uc131\uc73c\ub85c \uc790\ub9ac\ub9e4\uae40\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

(I) \uc8fc\ub984 \uc81c\uac70\uc81c<\/h3>\n

\ub098\uc774\uac00 \ub4e4\uba74\uc11c \ud53c\ubd80\uc758 \ucf5c\ub77c\uac90\uacfc \uc5d8\ub77c\uc2a4\ud2f4 \uc591\uc774 \uc810\ucc28 \uac10\uc18c\ud558\uc5ec \ud53c\ubd80 \ud0c4\ub825\uacfc \uacac\uace0\uc131\uc774 \ub5a8\uc5b4\uc9c0\uace0 \uc8fc\ub984\uc774 \uc0dd\uae30\uae30 \uc2dc\uc791\ud569\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ub9c8\ubc95\uc758 \uc8fc\ub984 \uc81c\uac70\uc81c\ucc98\ub7fc \uc791\uc6a9\ud558\uc5ec \uc774\ub7ec\ud55c \ub178\ud654 \uacfc\uc815\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \ub9c9\uc544\uc90d\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\uc758 \uc8fc\ub984 \ubc29\uc9c0 \uba54\ucee4\ub2c8\uc998\uc740 \uc8fc\ub85c \ubbf8\ud1a0\ud30c\uc9c0 \ud65c\uc131\ud654\uc640 \ucf5c\ub77c\uac90 \ud569\uc131 \ucd09\uc9c4\uc5d0 \uae30\ubc18\ud569\ub2c8\ub2e4. \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 \uc138\ud3ec\uc758 “\uc5d0\ub108\uc9c0 \uacf5\uc7a5”\uc785\ub2c8\ub2e4. \ub098\uc774\uac00 \ub4e4\uba74\uc11c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uae30\ub2a5\uc774 \uc810\ucc28 \uac10\uc18c\ud558\uace0 \uc190\uc0c1\ub41c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uac00 \ucd95\uc801\ub418\uc5b4 \uc5d0\ub108\uc9c0 \uc0dd\uc0b0 \ud6a8\uc728\uc774 \ub5a8\uc5b4\uc9c0\uace0 \ub2e4\ub7c9\uc758 \ud65c\uc131\uc0b0\uc18c(ROS)\uac00 \ubc29\ucd9c\ub418\uc5b4 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub97c \uc720\ubc1c\ud558\uace0 \uc138\ud3ec \ub178\ud654\ub97c \uac00\uc18d\ud654\ud569\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc190\uc0c1\ub41c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub97c \uc778\uc2dd\ud558\uace0 \uc81c\uac70\ud558\ub294 \uc138\ud3ec \uc790\uc815 \uc791\uc6a9 \uae30\uc804\uc778 \ubbf8\ud1a0\ud30c\uc9c0\ub97c \ud65c\uc131\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 PINK1(PTEN \uc720\ub3c4 \ucd94\uc815 \ud0a4\ub098\uc544\uc81c 1) \ubc0f \ud30c\ud0a8 \ub2e8\ubc31\uc9c8\uacfc \uac19\uc740 \ud575\uc2ec \ubd84\uc790\ub97c \u200b\u200b\uc870\uc808\ud558\uc5ec \ubbf8\ud1a0\ud30c\uc9c0\ub97c \uc2dc\uc791\ud569\ub2c8\ub2e4. PINK1 \ub2e8\ubc31\uc9c8\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uac00 \uc190\uc0c1\ub418\uba74 \ucd95\uc801\ub418\uc5b4 \ud30c\ud0a8 \ub2e8\ubc31\uc9c8\uc744 \uc774\uc6a9\ud558\uc5ec \uc190\uc0c1\ub41c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub97c \ud45c\uc9c0\ud569\ub2c8\ub2e4. \uc774\ud6c4 \uc190\uc0c1\ub41c \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 \uc790\uac00\ud3ec\uc2dd\uc18c\uccb4\uc5d0 \uc758\ud574 \ud3ec\uc704\ub418\uc5b4 \ubd84\ud574\ub429\ub2c8\ub2e4. \uc774\ub97c \ud1b5\ud574 \ub178\ud654 \uc138\ud3ec\uc5d0\uc11c \uae30\ub2a5 \uc7a5\uc560\uac00 \uc788\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \uc81c\uac70\ud558\uc5ec \uac74\uac15\ud55c \ub0b4\ubd80 \ud658\uacbd\uc744 \uc870\uc131\ud558\uace0 \ud53c\ubd80 \uc138\ud3ec\uc758 \uc5d0\ub108\uc9c0 \ub300\uc0ac\ub97c \uac1c\uc120\ud569\ub2c8\ub2e4.<\/p>\n

\ub3d9\uc2dc\uc5d0 \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ud615\uc9c8\uc804\ud658 \uc131\uc7a5 \uc778\uc790-\u03b2(TGF-\u03b2)\/Smad \uacbd\ub85c\ub97c \ud65c\uc131\ud654\ud558\uc5ec \ucf5c\ub77c\uac90 \ud569\uc131\uc744 \uc99d\uac00\uc2dc\ud0a4\uace0, \ucf5c\ub77c\uac90 \uc720\uc804\uc790(\uc608: COL1A1 \ubc0f COL3A1)\uc758 \ubc1c\ud604\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c, MMP(\uae30\uc9c8 \uae08\uc18d\ub2e8\ubc31\ubd84\ud574\ud6a8\uc18c), \ud2b9\ud788 MMP-1, MMP-3, MMP-9\uc758 \ud65c\uc131\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4. MMP\ub294 \ucf5c\ub77c\uac90\uacfc \uae30\ud0c0 \uc138\ud3ec\uc678 \uae30\uc9c8 \uc131\ubd84\uc744 \ubd84\ud574\ud558\ub294 \ud6a8\uc18c\ub85c, \ud53c\ubd80 \ub178\ud654 \uacfc\uc815\uc5d0\uc11c \ud65c\uc131\uc774 \uc99d\uac00\ud558\uc5ec \ucf5c\ub77c\uac90 \ubd84\ud574\ub97c \ucd09\uc9c4\ud569\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 MMP\uc758 \ud65c\uc131\uc744 \uc5b5\uc81c\ud558\uace0 \ucf5c\ub77c\uac90 \ubd84\ud574\ub97c \uac10\uc18c\uc2dc\ud0a4\uba70, \ucf5c\ub77c\uac90 \ud569\uc131\uc744 \ucd09\uc9c4\ud558\ub294 \ud6a8\uacfc\uc640 \uacb0\ud569\ud558\uc5ec \ud53c\ubd80 \uc8fc\ub984\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uac1c\uc120\ud558\uace0 \ud53c\ubd80 \ud0c4\ub825\uacfc \uc724\uae30\ub97c \ud68c\ubcf5\uc2dc\ucf1c \uc90d\ub2c8\ub2e4.<\/p>\n

(II) \ud53c\ubd80 \uc7ac\uc0dd \uc804\ubb38\uac00<\/h3>\n

\uc77c\uc0c1\uc0dd\ud65c\uc5d0\uc11c \ud53c\ubd80\ub294 \ud587\ubcd5, \uc54c\ub808\ub974\uae30, \uc5fc\uc99d \ub4f1 \ub2e4\uc591\ud55c \uc190\uc0c1\uc73c\ub85c \uace0\ud1b5\ubc1b\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc0c1\ud669\uc5d0\uc11c\ub294 \uac15\ub825\ud55c \ud53c\ubd80 \uc7ac\uc0dd \uc804\ubb38\uac00\uac00 \ud544\uc694\ud558\uba70, \uc6b0\ub864\ub9ac\ud2f4 A\uac00 \ubc14\ub85c \uadf8\ub7ec\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc885\uc591\uad34\uc0ac\uc778\uc790-\u03b1(TNF-\u03b1) \ubc0f \uc778\ud130\ub8e8\ud0a8-6(IL-6)\uacfc \uac19\uc740 \ub2e4\uc591\ud55c \uc5fc\uc99d \ub9e4\uac1c\uccb4\uc758 \uc0dd\uc131\uc744 \uc5b5\uc81c\ud558\uc5ec \ud0c1\uc6d4\ud55c \ud56d\uc5fc \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \ud53c\ubd80\uac00 \uc678\ubd80 \uc694\uc778\uc5d0 \uc758\ud574 \uc790\uadf9\uc744 \ubc1b\uc544 \uc5fc\uc99d \ubc18\uc751\uc774 \ubc1c\uc0dd\ud558\uba74 \uc774\ub7ec\ud55c \uc5fc\uc99d \ub9e4\uac1c\uccb4\uac00 \ub300\ub7c9\uc73c\ub85c \ubc29\ucd9c\ub418\uc5b4 \ubc1c\uc801, \ubd80\uae30, \uac00\ub824\uc6c0, \ud1b5\uc99d \ub4f1\uc758 \uc99d\uc0c1\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc5fc\uc99d \ub9e4\uac1c\uccb4 \uc0dd\uc131\uc744 \uc5b5\uc81c\ud558\uc5ec \uc5fc\uc99d \ubc18\uc751\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uac10\uc18c\uc2dc\ud0a4\uace0 \ud53c\ubd80 \ubd88\ud3b8\ud568\uc744 \uc644\ud654\ud569\ub2c8\ub2e4.<\/p>\n

\ud53c\ubd80 \uc190\uc0c1 \ubcf5\uad6c \ubaa8\ub378\uc5d0\uc11c \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc0c1\ucc98 \uce58\uc720\ub97c \ucd09\uc9c4\ud558\uace0 \ud749\ud130 \ud615\uc131\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uac01\uc9c8\ud615\uc131\uc138\ud3ec\uc758 \uc99d\uc2dd\uacfc \ubd84\ud654\ub97c \uc790\uadf9\ud558\uace0, \ubbf8\ud1a0\uac90 \ud65c\uc131\ud654 \ub2e8\ubc31\uc9c8 \ud0a4\ub098\uc544\uc81c(MAPK) \uacbd\ub85c\ub97c \ud65c\uc131\ud654\ud558\uc5ec \uc0ac\uc774\ud074\ub9b0 \ub2e8\ubc31\uc9c8(\uc608: \uc0ac\uc774\ud074\ub9b0 D1)\uc758 \ubc1c\ud604\uc744 \uc99d\uac00\uc2dc\ud0a4\uba70, \uac01\uc9c8\ud615\uc131\uc138\ud3ec\uac00 \uc815\uc9c0\uae30\uc5d0\uc11c \uc99d\uc2dd\uae30\ub85c \uc804\ud658\ub418\ub3c4\ub85d \ucd09\uc9c4\ud558\uc5ec \ud53c\ubd80 \uc138\ud3ec \uc7ac\uc0dd\uc744 \uac00\uc18d\ud654\ud569\ub2c8\ub2e4. \ub3d9\uc2dc\uc5d0, \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ucf00\ub77c\ud2f4 \uc720\uc804\uc790 \ub4f1 \uac01\uc9c8\uc138\ud3ec \ubd84\ud654 \uad00\ub828 \uc720\uc804\uc790\uc758 \ubc1c\ud604\uc744 \uc870\uc808\ud558\uc5ec \uac01\uc9c8\uce35 \uad6c\uc870\ub97c \ub354\uc6b1 \uc870\ubc00\ud558\uace0 \uc9c8\uc11c \uc788\uac8c \ub9cc\ub4e4\uace0, \ud53c\ubd80 \uc7a5\ubcbd \uae30\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uba70, \uc190\uc0c1\ub41c \ud53c\ubd80 \uc138\ud3ec\uc758 \ud68c\ubcf5 \ubc0f \uc7ac\uc0dd\uc744 \ucd09\uc9c4\ud558\uace0, \ud53c\ubd80\ub97c \uac74\uac15\ud55c \uc0c1\ud0dc\ub85c \ud68c\ubcf5\uc2dc\ud0b5\ub2c8\ub2e4.<\/p>\n

(III) \ubcf4\uc2b5 “\uc791\uc740 \uc218\ud638\uc790”<\/h3>\n

\ud53c\ubd80\uc758 \ubcf4\uc2b5 \ub2a5\ub825\uc740 \ud53c\ubd80 \uac74\uac15\uacfc \uc544\ub984\ub2e4\uc6c0\uc744 \uc720\uc9c0\ud558\ub294 \ub370 \ub9e4\uc6b0 \uc911\uc694\ud569\ub2c8\ub2e4. \uac74\uc131 \ud53c\ubd80\ub294 \uac70\uce60\uace0 \uac01\uc9c8\uc774 \uc77c\uc5b4\ub098\uae30 \uc26c\uc6b0\uba70, \uc794\uc8fc\ub984\uacfc \uac19\uc740 \ubb38\uc81c\uac00 \ubc1c\uc0dd\ud558\uae30 \uc27d\uc2b5\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 “\uc791\uc740 \uc218\ud638\uc790”\ucc98\ub7fc \ud53c\ubd80 \uc7a5\ubcbd \uae30\ub2a5\uc744 \uac15\ud654\ud558\uace0 \ubcf4\uc2b5\ub825\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uba70 \uc218\ubd84 \uc190\uc2e4\uc744 \uc608\ubc29\ud569\ub2c8\ub2e4. \ud53c\ubd80 \uc7a5\ubcbd \uae30\ub2a5\uc740 \uc8fc\ub85c \uac01\uc9c8\uce35\uacfc \ud53c\ubd80 \uc9c0\uc9c8\ub85c \uad6c\uc131\ub418\uc5b4 \uc788\uc73c\uba70, \uac01\uc9c8\uce35\uacfc \ud53c\ubd80 \uc9c0\uc9c8\uc5d0 \uc874\uc7ac\ud558\ub294 \ucc9c\uc5f0 \ubcf4\uc2b5 \uc778\uc790\ub294 \ud53c\ubd80\uc758 \uc218\ubd84 \uade0\ud615\uc744 \uc720\uc9c0\ud558\uae30 \uc704\ud574 \ud568\uaed8 \uc791\uc6a9\ud569\ub2c8\ub2e4. \ub098\uc774\uac00 \ub4e4\uac70\ub098 \uc678\ubd80 \ud658\uacbd \uc694\uc778\uc758 \uc601\ud5a5\uc744 \ubc1b\uc73c\uba74 \ud53c\ubd80 \uc7a5\ubcbd \uae30\ub2a5\uc774 \uc57d\ud574\uc838 \uc218\ubd84 \uc190\uc2e4\uc774 \ub354\uc6b1 \ube68\ub77c\uc9d1\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uac01\uc9c8\uc138\ud3ec \ubd84\ud654 \uad00\ub828 \uc720\uc804\uc790\uc758 \ubc1c\ud604\uc744 \uc870\uc808\ud558\uc5ec \uac01\uc9c8\uce35 \uad6c\uc870\ub97c \ub354\uc6b1 \uce58\ubc00\ud558\uace0 \uc9c8\uc11c \uc788\uac8c \ub9cc\ub4e4\uace0 \ud53c\ubd80 \uc7a5\ubcbd \uae30\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \ub3d9\uc2dc\uc5d0 \ud788\uc54c\ub8e8\ub860\uc0b0\uacfc \uac19\uc740 \ud53c\ubd80 \uc138\ud3ec \ub0b4 \ucc9c\uc5f0 \ubcf4\uc2b5 \uc778\uc790\uc758 \ud569\uc131\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ucc9c\uc5f0 \ubcf4\uc2b5 \uc778\uc790\ub294 \uac15\ub825\ud55c \ubcf4\uc2b5\ub825\uc744 \uac00\uc9c0\uace0 \uc788\uc5b4 \ub2e4\ub7c9\uc758 \uc218\ubd84\uc744 \ud761\uc218\ud558\uace0 \ud53c\ubd80\ub97c \ucd09\ucd09\ud558\uac8c \uc720\uc9c0\ud569\ub2c8\ub2e4.\"\"<\/p>\n

\uc2dd\ud488 \uc0b0\uc5c5\uc758 \uc7a0\uc7ac\uc801 \uc2a4\ud0c0<\/h2>\n

\uac74\uac15\uc5d0 \ub300\ud55c \uc778\uc2dd\uc774 \ub192\uc544\uc9d0\uc5d0 \ub530\ub77c, \uc0ac\ub78c\ub4e4\uc758 \uc74c\uc2dd\uc5d0 \ub300\ud55c \uc218\uc694\ub294 \ub354 \uc774\uc0c1 \ub2e8\uc21c\ud788 \ubc30\ub97c \ucc44\uc6b0\ub294 \ub370 \uad6d\ud55c\ub418\uc9c0 \uc54a\uace0 \uc601\uc591\uacfc \uac74\uac15\uc5d0 \ucd08\uc810\uc744 \ub9de\ucd94\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc2dd\ud488 \uc0b0\uc5c5\uc5d0\uc11c \uc6b0\ub864\ub9ac\ud2f4 A\uc758 \ud65c\uc6a9\uc740 \uc774\ub7ec\ud55c \ucd94\uc138\uc5d0 \uc644\ubcbd\ud558\uac8c \ubd80\ud569\ud558\uba70, \uc5c5\uacc4\uc5d0 \uc0c8\ub85c\uc6b4 \uac1c\ubc1c \uae30\ud68c\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n

(I) \uae30\ub2a5\uc131 \uc2dd\ud488\uc758 \uc0c8\ub85c\uc6b4 \ud310\ub9e4 \ud3ec\uc778\ud2b8<\/h3>\n

\uac74\uac15\ud55c \ub77c\uc774\ud504\uc2a4\ud0c0\uc77c\uc744 \ucd94\uad6c\ud558\ub294 \uc18c\ube44\uc790\ub4e4\uc774 \uae30\ub2a5\uc131 \uc2dd\ud488\uc5d0 \ub300\ud55c \uc218\uc694\ub97c \ud655\ub300\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud56d\uc0b0\ud654, \ud56d\uc5fc\uc99d, \uc5d0\ub108\uc9c0 \ub300\uc0ac \uac1c\uc120 \ub4f1 \ub2e4\uc591\ud55c \uac74\uac15\uc0c1\uc758 \uc774\uc810\uc744 \uc9c0\ub2cc \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uae30\ub2a5\uc131 \uc2dd\ud488 \ubd84\uc57c\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \uc778\uae30 \ud488\ubaa9\uc73c\ub85c \ub5a0\uc62c\ub790\uc2b5\ub2c8\ub2e4. \uc74c\ub8cc \uc0b0\uc5c5\uc5d0\uc11c\ub3c4 \uc77c\ubd80 \uae30\uc5c5\ub4e4\uc774 \uc6b0\ub864\ub9ac\ud2f4 A\ub97c \ucca8\uac00\ud55c \uae30\ub2a5\uc131 \uc74c\ub8cc\ub97c \ucd9c\uc2dc\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc74c\ub8cc\ub294 \uc77c\ubc18 \uc74c\ub8cc\ucc98\ub7fc \uc218\ubd84\uc744 \ubcf4\ucda9\ud560 \ubfd0\ub9cc \uc544\ub2c8\ub77c, \ud65c\uc131\uc0b0\uc18c\ub85c \uc778\ud55c \uc190\uc0c1\uc744 \ub9c9\uace0 \uc5fc\uc99d \ubc18\uc751\uc744 \uc904\uc774\uba70 \uc5d0\ub108\uc9c0 \ub300\uc0ac\ub97c \uac1c\uc120\ud558\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc90d\ub2c8\ub2e4. \uac74\uac15\uc744 \uc911\uc2dc\ud558\ub294 \uc18c\ube44\uc790\ub4e4\uc5d0\uac8c \ub9db\uc788\ub294 \uc74c\ub8cc\ub97c \uc990\uae30\uba74\uc11c \ucd94\uac00\uc801\uc778 \uac74\uac15\uc0c1\uc758 \uc774\uc810\uc744 \uc5bb\ub294 \uac83\uc740 \ubd84\uba85 \ub9e4\uc6b0 \ub9e4\ub825\uc801\uc778 \uc120\ud0dd\uc785\ub2c8\ub2e4. \uc74c\ub8cc \uc678\uc5d0\ub3c4 \uc694\uad6c\ub974\ud2b8, \uc5d0\ub108\uc9c0 \ubc14, \uadf8\ub9ac\uace0 \ub2e4\ub978 \uc2dd\ud488\ub4e4\ub3c4 \uc6b0\ub864\ub9ac\ud2f4 A\ub97c “\uac74\uac15 \uc694\uc18c”\ub85c \ud65c\uc6a9\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc694\uac70\ud2b8\uc5d0 \uc6b0\ub864\ub9ac\ud2f4 A\ub97c \ucca8\uac00\ud558\uba74 \ubcf8\ub798\uc758 \ub2ec\ucf64\uc0c8\ucf64\ud55c \ub9db\uc774\ub098 \ud48d\ubd80\ud55c \uc601\uc591 \uc131\ubd84\uc740 \uadf8\ub300\ub85c \uc720\uc9c0\ud558\uba74\uc11c \ud56d\uc0b0\ud654 \ubc0f \ud56d\uc5fc \ud6a8\uacfc\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc6b4\ub3d9 \ud6c4\ub098 \uc5ec\uac00 \uc2dc\uac04\uc5d0 \uc694\uac70\ud2b8\ub97c \uc990\uaca8 \uba39\ub294 \uc0ac\ub78c\ub4e4\uc5d0\uac8c \uc6b0\ub864\ub9ac\ud2f4 A\uac00 \ud48d\ubd80\ud55c \uc774 \uc694\uac70\ud2b8\ub294 \uac74\uac15\uacfc \ub9db\uc774\ub77c\ub294 \ub450 \ub9c8\ub9ac \ud1a0\ub07c\ub97c \ubaa8\ub450 \uc7a1\uc744 \uc218 \uc788\ub294 \uc81c\ud488\uc785\ub2c8\ub2e4. \uc5d0\ub108\uc9c0 \ubc14\uc5d0 \uc6b0\ub864\ub9ac\ud2f4 A\ub97c \ucca8\uac00\ud558\uba74 \uc2e0\uc9c4\ub300\uc0ac\ub97c \ucd09\uc9c4\ud558\uace0 \ud53c\ub85c\ub97c \uc904\uc774\ub294 \ub3d9\uc2dc\uc5d0 \ube60\ub978 \uc5d0\ub108\uc9c0 \ubcf4\ucda9 \ud6a8\uacfc\ub97c \uc5bb\uc744 \uc218 \uc788\uc5b4, \ud2b9\ud788 \uc57c\uc678 \ud65c\ub3d9\uc774\ub098 \uace0\uac15\ub3c4 \uc6b4\ub3d9\uc744 \uc790\uc8fc \ud558\ub294 \uc0ac\ub78c\ub4e4\uc5d0\uac8c \uc801\ud569\ud569\ub2c8\ub2e4. \uc2dc\uc7a5 \uc870\uc0ac \uc790\ub8cc\uc5d0 \ub530\ub974\uba74, \uc6b0\ub864\ub9ac\ud2f4 A\ub97c \ud568\uc720\ud55c \uae30\ub2a5\uc131 \uc2dd\ud488 \uc2dc\uc7a5 \uaddc\ubaa8\ub294 \ub9e4\ub144 \ud655\ub300\ub418\uace0 \uc788\uc73c\uba70, \ud5a5\ud6c4 \uba87 \ub144 \ub3d9\uc548 \uc131\uc7a5\ub960\uc774 [X]%\ub97c \uc0c1\ud68c\ud560 \uac83\uc73c\ub85c \uc608\uc0c1\ub429\ub2c8\ub2e4. \uc774\ub294 \uae30\ub2a5\uc131 \uc2dd\ud488 \ubd84\uc57c\uc5d0\uc11c \uc6b0\ub864\ub9ac\ud2f4 A\uc758 \ub9c9\ub300\ud55c \uc7a0\uc7ac\ub825\uc744 \uc5ec\uc2e4\ud788 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.<\/p>\n

(II) \uc2dd\ud488 \ubcf4\uc874\uc758 \uc0c8\ub85c\uc6b4 \ubcf4\ubb3c \ucc3d\uace0<\/h3>\n

\uc2dd\ud488 \ubcf4\uc874\uc740 \uc2dd\ud488\uc758 \ud488\uc9c8, \ub9db, \uc548\uc804\uc131\uacfc \uc9c1\uacb0\ub418\uae30 \ub54c\ubb38\uc5d0 \uc2dd\ud488 \uc0b0\uc5c5\uc758 \ud575\uc2ec \uacfc\uc81c\uc600\uc2b5\ub2c8\ub2e4. \ub6f0\uc5b4\ub09c \ud56d\uc0b0\ud654 \ud2b9\uc131\uc744 \uc9c0\ub2cc \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc2dd\ud488 \ubcf4\uc874\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \ud574\uacb0\ucc45\uc744 \uc81c\uc2dc\ud558\uba70, \uc2dd\ud488 \ubcf4\uc874\uc744 \uc704\ud55c “\uc0c8\ub85c\uc6b4 \ub9c8\ubc95\uc758 \ubb34\uae30”\ub85c \uc790\ub9ac\ub9e4\uae40\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc2dd\ud488 \uac00\uacf5 \ubc0f \ubcf4\uad00 \uacfc\uc815\uc5d0\uc11c \uae30\ub984\uc740 \uc27d\uac8c \uc0b0\ud654\ub418\uace0 \uc0b0\ud328\ub418\uc5b4 \uc774\ucde8, \ubd80\ud328, \uadf8\ub9ac\uace0 \uc601\uc591\uac00\uc758 \ud604\uc800\ud55c \uac10\uc18c\ub97c \ucd08\ub798\ud569\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uae30\ub984\uc758 \uc0b0\ud654 \uc0b0\ud328 \uacfc\uc815\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uc5b5\uc81c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub3d9\uc77c\ud55c \ubcf4\uad00 \uc870\uac74\uc5d0\uc11c \uc2dd\uc6a9\uc720\uc5d0 \ub300\ud55c \uc2e4\ud5d8\uc5d0\uc11c, \uc6b0\ub864\ub9ac\ud2f4 A\ub97c \ucca8\uac00\ud55c \uc2dd\uc6a9\uc720\uc758 \uacfc\uc0b0\ud654\ubb3c\uac00\ub294 \uc6b0\ub864\ub9ac\ud2f4 A\ub97c \ucca8\uac00\ud558\uc9c0 \uc54a\uc740 \uc2dd\uc6a9\uc720\ubcf4\ub2e4 \uc720\uc758\ubbf8\ud558\uac8c \ub0ae\uc740 \uc218\uc900\uc73c\ub85c \uc99d\uac00\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc6b0\ub864\ub9ac\ud2f4 A\uac00 \uae30\ub984\uc758 \uc0b0\ud654 \uc18d\ub3c4\ub97c \ub2a6\ucd94\uace0 \uc720\ud1b5\uae30\ud55c\uc744 \uc5f0\uc7a5\ud560 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4. \uacac\uacfc\ub958\ub098 \ud280\uae34 \uc74c\uc2dd\uacfc \uac19\uc774 \uae30\ub984\uc774 \ud48d\ubd80\ud55c \uc77c\ubd80 \uc2dd\ud488\uc758 \uacbd\uc6b0, \uc6b0\ub864\ub9ac\ud2f4 A\ub97c \ucca8\uac00\ud558\uba74 \uc2dd\ud488\uc758 \ud48d\ubbf8\uc640 \uc601\uc591\uac00\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \uc720\uc9c0\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uacac\uacfc\ub958\ub294 \uae30\ub984\uc758 \uc0b0\ud654\ub85c \uc778\ud574 \ubcf4\uad00 \uc911 \uc0b0\ud328\uac00 \ubc1c\uc0dd\ud558\uae30 \uc27d\uace0, \uc774\ub294 \ub9db\uacfc \ud488\uc9c8\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc6b0\ub864\ub9ac\ud2f4 A\uac00 \ucca8\uac00\ub41c \uacac\uacfc\ub958\ub294 \uc7a5\uae30 \ubcf4\uad00 \ud6c4\uc5d0\ub3c4 \ubc14\uc0ad\ud55c \uc2dd\uac10\uacfc \ud48d\ubd80\ud55c \uc601\uc591\uc18c\ub97c \uc720\uc9c0\ud569\ub2c8\ub2e4. \uc774\ub294 \uc0b0\ud654 \ubc0f \ubd80\ud328\ub85c \uc778\ud55c \uc74c\uc2dd\ubb3c \uc4f0\ub808\uae30\ub97c \uc904\uc77c \ubfd0\ub9cc \uc544\ub2c8\ub77c \uc18c\ube44\uc790\uc5d0\uac8c \ub354 \uc548\uc804\ud558\uace0 \uac74\uac15\ud558\uba70 \ub9db\uc788\ub294 \uc2dd\ud488\uc744 \uc81c\uacf5\ud558\uc5ec \uc2dd\ud488 \uc0b0\uc5c5\uc758 \uc9c0\uc18d \uac00\ub2a5\ud55c \ubc1c\uc804\uc5d0 \ub9e4\uc6b0 \uc911\uc694\ud569\ub2c8\ub2e4.<\/p>\n

\uc870\uc9c1 \ubcf5\uad6c \ubc0f \uc7ac\uc0dd\uc744 \uc704\ud55c “\ubd80\uc2a4\ud130”<\/h3>\n

\ube60\ub978 \ud608\uad00\uc2e0\uc0dd\uc740 \uc870\uc9c1 \uc190\uc0c1\uc774\ub098 \uc7a5\uae30 \uc774\uc2dd \ud6c4 \uc870\uc9c1 \ubcf5\uad6c \ubc0f \uc7ac\uc0dd\uc5d0 \ub9e4\uc6b0 \uc911\uc694\ud569\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc774 \uacfc\uc815\uc5d0\uc11c \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\uba70, \ud608\uad00\uc2e0\uc0dd\uacfc \uc138\ud3ec \uc99d\uc2dd\uc744 \ucd09\uc9c4\ud558\uc5ec \uc870\uc9c1 \ubcf5\uad6c \ubc0f \uc7ac\uc0dd\uc744 \uac00\uc18d\ud654\ud558\uace0, \ud654\uc0c1 \ubc0f \uc0c1\ucc98 \uce58\uc720\uc5d0 \uc7a0\uc7ac\uc801\uc73c\ub85c \ud65c\uc6a9\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud654\uc0c1 \uce58\ub8cc\uc5d0\uc11c \uc911\uc99d \ud654\uc0c1 \ud658\uc790\ub294 \uad11\ubc94\uc704\ud55c \ud53c\ubd80 \uc190\uc0c1, \ub192\uc740 \uac10\uc5fc \uc704\ud5d8, \ub290\ub9b0 \uce58\uc720 \uc18d\ub3c4\uc640 \uac19\uc740 \uc5b4\ub824\uc6c0\uc5d0 \uc9c1\uba74\ud569\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \ud654\uc0c1 \ubd80\uc704\uc758 \ud608\uad00\uc2e0\uc0dd\uc744 \ucd09\uc9c4\ud558\uc5ec \uc190\uc0c1\ub41c \uc870\uc9c1\uc5d0 \ucda9\ubd84\ud55c \uc0b0\uc18c\uc640 \uc601\uc591\ubd84\uc744 \uacf5\uae09\ud558\uace0, \ud53c\ubd80 \uc138\ud3ec\uc758 \uc99d\uc2dd\uacfc \uc774\ub3d9\uc744 \ucd09\uc9c4\ud558\uba70, \uc0c1\ucc98 \uce58\uc720\ub97c \ucd09\uc9c4\ud569\ub2c8\ub2e4. \uad00\ub828 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ud654\uc0c1 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c \uc6b0\ub864\ub9ac\ud2f4 A \ud22c\uc5ec\ub294 \uc0c1\ucc98 \uce58\uc720 \uc2dc\uac04\uc744 \ud06c\uac8c \ub2e8\ucd95\ud558\uace0 \ud749\ud130 \uc870\uc9c1 \ud615\uc131\uc744 \uac10\uc18c\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc0c1\ucc98 \uce58\uc720, \uc0ac\uace0, \uc218\uc220 \ub4f1\uc73c\ub85c \uc778\ud55c \uc870\uc9c1 \uc678\uc0c1 \uc2dc, \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc12c\uc720\uc544\uc138\ud3ec \uc99d\uc2dd\uacfc \ucf5c\ub77c\uac90 \ud569\uc131\uc744 \uc790\uadf9\ud558\uc5ec \uc0c1\ucc98 \uc218\ucd95 \ubc0f \uc0c1\ud53c\ud654\ub97c \ucd09\uc9c4\ud558\uace0, \uc190\uc0c1\ub41c \uc870\uc9c1\uc758 \uc815\uc0c1\uc801\uc778 \uad6c\uc870\uc640 \uae30\ub2a5\uc744 \uc2e0\uc18d\ud558\uac8c \ud68c\ubcf5\ud558\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc904 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub2f9\ub1e8\ubcd1\uc131 \uc871\ubd80 \uada4\uc591\uacfc \uac19\uc740 \uc77c\ubd80 \ub9cc\uc131 \uc0c1\ucc98 \uce58\ub8cc\uc5d0\uc11c \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uad6d\uc18c \ud608\uc561 \uc21c\ud658\uc744 \uac1c\uc120\ud558\uace0 \uc138\ud3ec \uc99d\uc2dd\uc744 \ucd09\uc9c4\ud568\uc73c\ub85c\uc368 \uc774\ub7ec\ud55c \uce58\uc720\uac00 \uc5b4\ub824\uc6b4 \uc0c1\ucc98\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \uce58\ub8cc \uc635\uc158\uc744 \uc81c\uacf5\ud560 \uc218 \uc788\uc744 \uac83\uc73c\ub85c \uae30\ub300\ub429\ub2c8\ub2e4.\"\"<\/p>\n

\uc694\uc57d \ubc0f \uc804\ub9dd<\/h2>\n

\ub3c5\ud2b9\ud55c \uc0dd\ubb3c\ud559\uc801 \ud2b9\uc131\uc744 \uc9c0\ub2cc \ucc9c\uc5f0 \ud3f4\ub9ac\ud398\ub180 \ub300\uc0ac\uc0b0\ubb3c\uc778 \uc6b0\ub864\ub9ac\ud2f4 A\ub294 \uc758\uc57d\ud488, \uac74\uac15 \uc81c\ud488, \ud654\uc7a5\ud488, \uc2dd\ud488, \uc870\uc9c1 \uc7ac\uc0dd \ub4f1 \ub2e4\uc591\ud55c \ubd84\uc57c\uc5d0\uc11c \ud0c1\uc6d4\ud55c \uc751\uc6a9 \uac00\uce58\ub97c \uc785\uc99d\ud574 \uc654\uc2b5\ub2c8\ub2e4. \uc81c\uc57d \ubd84\uc57c\uc5d0\uc11c\ub294 \uc2ec\ud608\uad00 \uc9c8\ud658 \ubc0f \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658 \uce58\ub8cc\uc5d0 \uc0c8\ub85c\uc6b4 \ud76c\ub9dd\uc744 \uc81c\uc2dc\ud558\ub294 \ub3d9\uc2dc\uc5d0 \uac15\ub825\ud55c \ud56d\uc5fc\uc99d, \ud56d\ub178\ud654, \uba74\uc5ed \uc870\uc808 \ud6a8\ub2a5\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uac74\uac15 \uc81c\ud488 \ubd84\uc57c\uc5d0\uc11c\ub294 \ud56d\uc0b0\ud654, \uccb4\uc911 \uad00\ub9ac, \uadfc\uc721 \uac74\uac15 \uc720\uc9c0\uc5d0 \ud0c1\uc6d4\ud55c \ud6a8\ub2a5\uc744 \ubcf4\uc785\ub2c8\ub2e4. \ud654\uc7a5\ud488 \uc5c5\uacc4\uc5d0\uc11c\ub294 \uc8fc\ub984 \uac1c\uc120, \uc7ac\uc0dd, \ubcf4\uc2b5 \ud6a8\uacfc\ub85c \ub178\ud654 \ubc29\uc9c0\uc5d0 \uc0c8\ub85c\uc6b4 \uc778\uae30\ub97c \uc5bb\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc2dd\ud488 \uc5c5\uacc4\uc5d0\uc11c\ub294 \uae30\ub2a5\uc131 \uc2dd\ud488\uc758 \uc0c8\ub85c\uc6b4 \ud310\ub9e4 \ud3ec\uc778\ud2b8\ub97c \uc81c\uacf5\ud558\uace0 \uc2dd\ud488 \ubcf4\uc874\uc758 \uc0c8\ub85c\uc6b4 \ubc29\ubc95\uc73c\ub85c \ud65c\uc6a9\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc870\uc9c1 \uc7ac\uc0dd \ubd84\uc57c\uc5d0\uc11c\ub294 \ud608\uad00 \uc2e0\uc0dd \ubc0f \uc138\ud3ec \uc99d\uc2dd \ucd09\uc9c4\uc5d0\ub3c4 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4.<\/p>\n

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\uc0dd\uba85\uacfc\ud559\uacfc \uac74\uac15 \ubd84\uc57c\ub97c \ud0d0\uad6c\ud558\ub2e4 \ubcf4\uba74, \ucc98\uc74c\uc5d0\ub294 \ud2c8\uc0c8\uc2dc\uc7a5\uc73c\ub85c \uc5ec\uaca8\uc84c\uc9c0\ub9cc \uc2ec\uce35\uc801\uc778 \uc5f0\uad6c\ub97c \ud1b5\ud574 \ub180\ub78d\ub3c4\ub85d \uad11\ubc94\uc704\ud55c \uc751\uc6a9 \ubd84\uc57c\ub97c \ubc1d\ud600\ub0b8 \ubb3c\uc9c8\ub4e4\uc774 \ud56d\uc0c1 \uc874\uc7ac\ud569\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 A\uac00 \ubc14\ub85c \uadf8\ub7ec\ud55c \uc608\uc785\ub2c8\ub2e4. \uc774\ub984\uc740 \uc0dd\uc18c\ud560 \uc218 \uc788\uc9c0\ub9cc, \uc2e0\uc9c4\ub300\uc0ac \uac74\uac15 \uc720\uc9c0\ubd80\ud130 \uc2e0\uacbd \ud1f4\ud589\uc131 \uc9c8\ud658 \ud1f4\uce58\uc5d0 \uc774\ub974\uae30\uae4c\uc9c0 \uc5ec\ub7ec \ud575\uc2ec \ubd84\uc57c\uc5d0\uc11c \uc870\uc6a9\ud788 \uc8fc\ubaa9\ubc1b\uace0 \uc788\uc73c\uba70, \uc2ec\uc9c0\uc5b4 \ubbf8\uc6a9 \ubc0f \uc2a4\ud0a8\ucf00\uc5b4 \ubd84\uc57c\uc5d0\uc11c\ub3c4 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc8fc\uba70 \uc5f0\uad6c\uc790\uc640 \uc5c5\uacc4\uc758 \uad00\uc2ec\uc744 \ub04c\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc6b0\ub864\ub9ac\ud2f4 … Continue reading \uc6b0\ub864\ub9ac\ud2f4 A\uff1a\uc791\uc740 \ubb3c\uc9c8\uc774\uc9c0\ub9cc \ub2e4\uc591\ud55c \uc6a9\ub3c4\ub85c \uc0ac\uc6a9 \uac00\ub2a5<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":2994,"parent":0,"menu_order":16,"comment_status":"open","ping_status":"open","template":"","format":"standard","meta":{"footnotes":""},"class_list":["post-2993","blog","type-blog","status-publish","format-standard","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog\/2993","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog"}],"about":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/types\/blog"}],"author":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/comments?post=2993"}],"version-history":[{"count":0,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/blog\/2993\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/media\/2994"}],"wp:attachment":[{"href":"https:\/\/www.focusherb.com\/kr\/wp-json\/wp\/v2\/media?parent=2993"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}