Food and Nutrition Ingredients
Pantethine
Pantethine (CAS:16816-67-4), also known as D-Pantethine, is the active metabolite of vitamin B5 (pantothenic acid) and a key component of Coenzyme A (CoA). It is a white to off-white crystalline powder with high water solubility and excellent biological activity, widely used in health products, pharmaceuticals, functional foods and cosmetics.
Our Pantethine is available in customizable purity (98%-99.5%) tested by HPLC, fully compliant with USP, EP, BP, FCC, HALAL, KOSHER, ISO22000 and GMP standards. It has high bioavailability, no side effects, and is perfect for cardiovascular health supplements, lipid-lowering products, energy metabolism boosters, natural cosmetics and pharmaceutical intermediates. Stable batch quality, bulk factory price, complete COA & export documents available.
Vitamin B5 Derivative
High Purity Pantethine
HPLC Tested
HALAL & KOSHER Certified
Multi-Industry Application
High Purity Pantethine
HPLC Tested
HALAL & KOSHER Certified
Multi-Industry Application
PRODUCT INTRODUCTION
| Product Name | Pantethine / D-Pantethine / Bis-pantethine |
| CAS No. | 16816-67-4 |
| Molecular Formula | C₂₂H₄₂N₄O₈S₂ |
| Molecular Weight | 554.72 g/mol |
| Source | Synthetic active metabolite of Vitamin B5 (Pantothenic Acid) |
| Pantethine Content (HPLC) | 98% / 99% / 99.5% (Customizable for high purity needs) |
| Solubility | Easily soluble in ethanol, methanol; slightly soluble in water |
| Moisture | ≤3.0% |
| Ash Content | ≤0.5% |
| pH (1% aqueous solution) | 5.0 ~ 7.0 |
| Heavy Metals | Pb≤0.5ppm, As≤0.3ppm, Cd≤0.1ppm, Hg≤0.01ppm |
| Microbiology | TPC≤500cfu/g, Yeast&Mold≤50cfu/g, Salmonella/E.Coli Negative |
| Impurity Content | Single impurity ≤0.5%, total impurities ≤1.0% (HPLC) |
| Allergen Status | Vegan, Gluten-Free, Non-GMO, Animal-Free, No Allergens |
| Storage Condition | Sealed, cool dry & dark warehouse (2-8℃ recommended for long-term storage), avoid moisture, high temperature and direct sunlight |
| Shelf Life | 24 months unopened original packaging (2-8℃ storage), 18 months at room temperature |
| MOQ | 1kg sample order, 25kg bulk export bag/drum; 100kg+ for long-term framework orders |
Core Benefits & Functional Mechanism
Pantethine is the biologically active form of vitamin B5, which is rapidly converted into Coenzyme A (CoA) in the human body. CoA is a key coenzyme involved in hundreds of metabolic reactions, including carbohydrate, lipid and protein metabolism, making Pantethine an essential raw material for maintaining human health.
Unlike ordinary vitamin B5, Pantethine has higher bioavailability and can directly participate in metabolic processes, exerting multiple health benefits. It has good compatibility with other functional ingredients, and can be compounded with vitamins, minerals and plant extracts to enhance product efficacy, adapting to various production processes such as tablet pressing, granulation, and liquid formulation.
- Lipid regulation: Inhibit cholesterol synthesis, reduce triglyceride and LDL (bad cholesterol) levels, increase HDL (good cholesterol) levels, protect cardiovascular health
- Cardiovascular protection: Improve blood circulation, reduce the risk of cardiovascular diseases, support heart health
- Energy metabolism: Promote the metabolism of carbohydrates, lipids and proteins, convert nutrients into energy, relieve fatigue and improve physical strength
- Neuroprotection: Support nerve cell health, improve nerve conduction function, and may help relieve symptoms of neurological diseases such as Alzheimer’s and Parkinson’s
- Skin care: Promote skin cell metabolism, enhance skin elasticity, reduce dryness and wrinkles, and improve skin state
- Natural safety: As a vitamin derivative, it has high safety, no obvious side effects, and is suitable for long-term use by adults and the elderly
Pantethine Production & Purification Process
Full Manufacturing Steps
- Raw material selection: Select high-purity vitamin B5 (pantothenic acid) and other auxiliary materials, strictly control impurity content
- Catalytic synthesis: Under specific temperature and pressure conditions, use advanced catalytic technology to synthesize Pantethine from raw materials
- Primary purification: Remove unreacted raw materials and by-products through solvent extraction and filtration
- High-precision purification: Use high-performance liquid chromatography (HPLC) for further purification to ensure purity reaches 98%+
- Crystallization: Control crystallization conditions to obtain high-quality Pantethine crystals with good fluidity
- Drying & grinding: Use vacuum freeze-drying technology to remove moisture, then grind to uniform particle size
- Testing & packaging: Conduct full-item testing (HPLC purity, heavy metals, microbiology), classify by specification, and seal in moisture-proof packaging
GMP closed production workshop, 100,000-class clean production environment, strict raw material control and multi-step purification process, ensuring high Pantethine content, stable activity, no harmful impurities, meeting pharmaceutical, health product and food-grade raw material requirements and global regulatory standards.
Factory Supply Capacity & Global Certifications
Specialized vitamin derivative production base, annual Pantethine output reaches 150 tons, multiple purity grades (98%, 99%) in regular stock, 8-12 tons spot inventory for fast small orders and large framework orders. Constant temperature (2-8℃) storage warehouse to avoid activity variation and moisture clumping.
Stable Bulk Supply Advantages
- Annual production capacity: 150 tons pharmaceutical/health/food grade Pantethine
- Regular spot inventory: 8~12 tons standard purity (98%, 99%) grades
- Custom high purity (99.5%) & particle size available
- 3~7 working days fast bulk delivery after deposit confirmation; 10~15 days for custom specifications
Batch COA & SDS Full Documents
- ISO22000 / FSSC22000 Global Food Safety Management System
- GMP 100,000 class vitamin derivative production workshop certification
- USP, EP, BP, FCC, JECFA & FDA GRAS Approval
- HALAL & KOSHER global religious export certification
- Third-party full batch testing & permanent traceability system
- Compliant with EU REACH, US FDA, Japan JHFA regulations
6 Core Competitive Advantages of Our Pantethine
High Purity & High Bioavailability
Advanced synthesis and multi-step purification process, HPLC tested purity ≥99%, high bioavailability, can be rapidly converted into CoA in the human body, exerting fast and significant efficacy.
Multi-functional Health Benefits
Integrate lipid regulation, cardiovascular protection, energy metabolism, neuroprotection and skin care effects, suitable for multiple product categories and market demands.
Strict Quality Control
Full-process quality monitoring, from raw material selection to finished product testing, no heavy metal pollution, no harmful impurities, compliant with global safety standards for pharmaceuticals and foods.
Global Regulatory Compliance
FDA, JECFA, FCC, EP, BP, HALAL, KOSHER certified, meets EU, US, Japan, Asia market pharmaceutical, health product and food raw material regulations.
Customized Service
Customizable purity (98%-99.5%), particle size, compound formulations, bulk & private label packaging to match different industry and customer needs.
Stable Bulk Supply
Annual output of 150 tons, large spot inventory, fast delivery (3-7 working days for standard products), support long-term framework orders with stable price and quality.
Request Free Sample & Bulk Quotation
Looking for a reliable supplier of high purity D-Pantethine raw material for nutritional supplements, sports nutrition, liver support and anti-fatigue health products?
Contact our team today to receive free samples, full COA specifications, global export certification documents and customized bulk pricing for your vitamin & cellular nutrition project.
Main Industrial Application Fields
Cardiovascular Health Products
Lipid-lowering capsules, tablets, regulate cholesterol, protect heart and blood vessel health
Energy Supplements
Sports nutrition products, energy drinks, promote metabolism, relieve fatigue and improve physical strength
Neurological Health Products
Nerve health supplements, support nerve cell function, suitable for middle-aged and elderly health care
Pharmaceutical Intermediates
Raw material for lipid-lowering, neuroprotective drugs, with high purity and stable activity
Natural Cosmetics
Facial creams, serums, promote skin metabolism, enhance elasticity and reduce wrinkles
Feed Additives
Livestock and poultry feed, improve animal metabolism, enhance immunity and growth performance
Strict QC Testing & Official Batch Documents
Every batch of Pantethine is tested for purity (HPLC), moisture, ash, heavy metals, microbial counts, impurity content and solubility, complying with USP, EP, BP, FCC specifications, to meet pharmaceutical, health product and food-grade raw material standards.
We provide official batch COA, HPLC purity test reports, SDS safety data sheets, HALAL/KOSHER/ISO/GMP certificates, third-party inspection reports, full batch traceability data, supporting import customs clearance, supplier audits and finished product registration in global markets.
Full Batch Traceability System
Unique batch number for each shipment, raw material source records, production process & test data permanently traceable for 5 years
OEM & Custom Formulation Service
Customizable Service Range
- Purity customization: 98% / 99% / 99.5% high purity grades for different application scenarios
- Particle size adjustment: Fine powder (80-120 mesh), ultrafine powder for tablet, capsule and liquid formulation needs
- Compound premix: Pantethine + Coenzyme Q10 / Fish Oil / Vitamin B Complex blend formulations
- Solubilization treatment: Improve water solubility for liquid beverage and oral liquid production
- 25kg bulk bags/drums, neutral packaging, private label custom bags/bottles/softgels
- Formulation technical guidance & application support for different industries, including dosage recommendation
Support long-term framework bulk orders, consistent purity & activity batch control, provide full regulatory documents (COA, SDS, certification copies) for global health product manufacturers and food brands to complete market registration and customs clearance.
How to buy Pantethine Powder?
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