Cosmetic Ingredients
Spermidine Trihydrochloride
Spermidine Trihydrochloride (CAS: 334-50-9) is a natural endogenous polyamine substance presented in human cells. White crystalline powder with excellent water solubility. Its core function is activating cellular autophagy, clearing senescent damaged organelles and redundant metabolic waste. Food grade is widely used in oral anti-aging capsules, tablets and solid drinks; cosmetic grade applies to anti-wrinkle essence, firming lotion and anti-photoaging skincare products.
We provide 99% high-purity spermidine trihydrochloride powder with food/cosmetic dual specifications, customized stable aqueous solution available on demand. Strict control of related impurities, heavy metals and microorganisms, compliant with FDA GRAS, CosIng, ISO22716, GMP, HALAL and KOSHER. Free samples and full COA & SDS documents are provided for brand formula development.
Spermidine TriHCl
99% High Purity
Water Soluble
Food & Cosmetic Dual Use
HALAL & KOSHER Certified
99% High Purity
Water Soluble
Food & Cosmetic Dual Use
HALAL & KOSHER Certified
PRODUCT INTRODUCTION
| Product Name | Spermidine Trihydrochloride, Spermidine 3HCl |
| CAS No. | 334-50-9 |
| Molecular Formula | C₇H₁₉N₃·3HCl |
| Molecular Weight | 254.63 g/mol |
| Appearance | White to off-white fine crystalline powder, odorless, hygroscopic |
| Assay (HPLC) | ≥99.0% (Food Grade & Cosmetic Grade unified standard) |
| Related Impurities | Single individual impurity ≤0.1%, total related impurities ≤0.5% |
| Solubility | Freely soluble in water; soluble in methanol; insoluble in grease & oils |
| pH (1% aqueous solution) | 2.8 ~ 4.2 |
| Loss on Drying | ≤0.4% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | Pb ≤0.1ppm, As ≤0.1ppm, Cd ≤0.05ppm, Hg ≤0.01ppm |
| Microbiological Index | TPC ≤100cfu/g, Mold & Yeast ≤10cfu/g, Pathogens Absent |
| Allergen Description | Non-GMO, Vegan, Gluten-Free, No artificial additives |
| Storage Requirements | Sealed moisture-proof & light-proof vacuum packaging, 2-15℃ cool storage; keep away from humidity, high temperature, sunlight |
| Unopened Shelf Life | 24 months under specified storage environment |
| MOQ | 5g sample support; bulk: 50g/1kg/5kg/25kg vacuum moisture-proof packing |
Core Benefits & Functional Mechanism of Spermidine Trihydrochloride
Spermidine is a key polyamine autophagy activator inside human cells. It induces cellular autophagy flow, accelerates lysosome digestion and clearance of aging mitochondria, damaged cell membranes and accumulated metabolic waste. Internally taken, it delays systemic aging, improves cell vitality, relieves chronic fatigue, and supports cardiovascular and nerve health. Topically applied on skin, it accelerates epidermal cell renewal, reduces fine lines caused by aging and UV damage, tightens loose texture, repairs photoaging, and improves dull tired skin.
Spermidine is highly hygroscopic and acidic; formulas need to control pH range and add stabilizers to prevent discoloration and degradation. Classic compound combinations: Spermidine + NAD+ + Resveratrol oral anti-aging set; Spermidine + Panthenol + Centella Asiatica topical repair anti-aging formula.
- Core autophagy activation: clear aging garbage, realize cell rejuvenation fundamentally
- Oral multi-system anti-aging: improve fatigue, maintain organ vitality, delay age decline
- Dermal anti-aging: fade fine lines, firm skin, repair UV damage, brighten tired dullness
- Excellent water solubility: compatible with tablets, drinks, essence, toner, mask all water-phase formulas
- Dual-grade design: food for oral use, cosmetic grade strictly controlled for skincare compliance
- Strong compound synergy: match mainstream anti-aging ingredients to build multi-dimensional anti-aging system
Formulation Operation Tips: Oral finished products conventional daily dosage 1-3mg; skincare recommended addition amount 0.01%~0.08%. Strictly control finished product pH 3.0~5.0, adopt amber opaque bottles, avoid high temperature processing and humid environment. Pregnant & breastfeeding people need doctor consultation before oral intake.
Spermidine Trihydrochloride Low-Temp Synthesis & Purification Process
Complete Production Steps
- High-purity raw material inspection, heavy metal & residual solvent pre-detection
- Closed low-temperature catalytic synthesis under nitrogen inert gas protection
- Multi-stage gradient recrystallization to separate polyamine miscellaneous impurities
- Activated carbon decolorization and membrane filtration to remove tiny by-products
- Vacuum low-temperature drying to obtain 99% spermidine trihydrochloride crystal powder
- Custom preparation of stabilized aqueous solution with pH adjustment and anti-hygroscopic additives
- Full HPLC testing, moisture-proof light-proof nitrogen vacuum sealed packaging
GMP water-soluble active closed clean workshop, full-process low temperature, low-humidity and light-shielded production, strictly control impurity content and moisture absorption index. Batches have stable solubility and color, fully meet global food and cosmetic raw material safety standards.
Factory Supply Capacity & Global Export Certifications
Professional GMP production base focusing on autophagy anti-amine raw materials. Annual total output of spermidine trihydrochloride reaches 5 tons, with 300kg conventional spot inventory. Constant temperature, low humidity and dark independent warehouse prevents moisture absorption and light degradation, stably supplies bulk goods to global long-life anti-aging health food and anti-wrinkle skincare OEM brands.
Stable Bulk Supply Advantages
- Annual capacity: 5 tons of food & cosmetic grade spermidine powder
- In-stock inventory: 300kg standard specification for fast shipment
- Custom liquid concentration, autophagy multi-ingredient blended premix powder
- 4~7 working days delivery for bulk orders, long-term framework exclusive preferential price/li>
Batch COA & SDS Full Official Documents
- ISO22716 / GMP unified production standards for food & cosmetic raw materials
- US FDA GRAS qualified, EU food safety + CosIng cosmetic filing compliant
- Dual HALAL & KOSHER certification for global religious market export
- Third-party full safety testing + complete batch traceability management system
- Support REACH, CPNP and overseas health food registration supporting documents
6 Core Competitive Advantages of Our Spermidine Trihydrochloride
99% High Purity Strict Low Impurity
Multi-step recrystallization purification, total impurities controlled below 0.5%, suitable for high-end formula.
Unique Autophagy Anti-Aging Mechanism
Different from common antioxidants, remove aging garbage from cell source to realize rejuvenation.
Excellent Water Solubility
All water-based formulas are compatible, covering oral drinks and all aqueous skincare products.
Food & Cosmetic Dual Grades
Separate production and testing of two grades to meet oral and cosmetic compliance requirements respectively.
Global Multi-Country Compliance
FDA GRAS & CosIng compliant, dual religious certification, complete cross-border filing materials.
Custom Compound & Formulation Support
Custom liquid concentration, compound anti-aging powder, packaging customization and formula technical service.
Request Free Sample & Bulk Quotation
Looking for a reliable supplier of high purity Spermidine Trihydrochloride raw material for longevity anti-aging supplements, cellular autophagy capsules and premium wellness nutritional formulations?
Contact our team today to receive free samples, full COA specifications, global export certification documents and customized bulk pricing for your anti-aging longevity health raw material project.
Main Industrial Application Fields for Spermidine Trihydrochloride
Autophagy Anti-Aging Capsules
Middle-aged and elderly longevity maintenance oral capsules
Anti-Aging Solid Beverage
Water-soluble spermidine instant powder drink
Anti-Fatigue Nourishing Tablets
Improve sub-health fatigue, cell vitality oral tablets
Anti-Wrinkle Firming Facial Serum
Anti-aging essence to smooth fine lines and firm sagging skin
Anti-Aging Repair Facial Mask
Water-phase mask for light aging dull skin repair
Compound Autophagy Anti-Aging Series
Spermidine + NAD+/Resveratrol high-end compound anti-aging line
Strict QC Testing & Official Batch Compliance Documents
Each batch of spermidine trihydrochloride undergoes full HPLC detection of main content and impurities, moisture, ignition residue, heavy metals, residual solvents and microbial full inspection, fully complying with ISO22716, FDA GRAS, CosIng global raw material standards.
We provide exclusive batch COA, HPLC spectrum, SDS safety data sheet, copies of HALAL/KOSHER/ISO/GMP certificates, food/cosmetic safety evaluation reports and full batch traceability files, supporting factory audits, global registration and customs clearance of health products and cosmetics.
Whole Batch Traceability System
Unique batch number records synthesis, purification, testing all links, permanently traceable for compliance audit
OEM & Custom Formulation Service for Spermidine Trihydrochloride
Customizable Service List
- 99% spermidine powder particle fineness customization
- Custom concentration stable aqueous solution, pH adjusted anti-hygroscopic liquid formula
- Autophagy compound premix: Spermidine + NAD+ + Resveratrol + Zinc blended powder
- Bulk moisture-proof nitrogen vacuum packaging: 50g/1kg/5kg/25kg, private label outer packaging
- Capsule, tablet, essence, mask formula guidance, stability testing support
We support long-term framework bulk orders with stable purity and low impurity indicators. Provide complete certification documents such as batch COA, SDS, safety assessment report to help cross-border health food and cosmetic brands complete regional filing and customs clearance smoothly.
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