Food and Nutrition Ingredients
DHH-B (Dihydrohonokiol-B) Powder
Dihydrohonokiol-B (CAS:35354-74-6) is a rare high-activity lignan monomer isolated from magnolia officinalis bark, white crystalline powder with strong lipophilicity. It exhibits stronger anti-inflammatory, anti-allergy and bacteriostatic capacity than conventional honokiol and magnolol. Food-grade Dihydrohonokiol-B is widely applied in anxiety relief, sleep improvement, systemic chronic inflammation oral capsules and tablets. Cosmetic grade is used for sensitive skin redness repair, hormone-dependent skin soothing, inflammatory acne and seborrhea control skincare.
We supply 98%/99% high-purity Dihydrohonokiol-B monomer powder and 50% standardized magnolia total lignan powder. Strictly control magnolia pesticide residues, heavy metals, residual solvents and microbiological indicators, compliant with FDA GRAS, CosIng, ISO22716, GMP, HALAL & KOSHER. Free test samples and complete COA & SDS documents are provided for formula development.
Magnolia Bark Lignan
Lipophilic
Anti-Sensitive Raw Material
HALAL & KOSHER Certified
PRODUCT INTRODUCTION
| Product Name | Dihydrohonokiol-B, Magnolia Officinalis Bark Lignan Extract |
| CAS No. | 35354-74-6 |
| Molecular Formula | C₁₈H₂₀O₂ |
| Molecular Weight | 272.35 g/mol |
| Appearance | White to off-white fine crystalline powder, characteristic faint magnolia herbal odor |
| Dihydrohonokiol-B Content (HPLC) | 50% / 98% / 99% |
| Related Lignan Impurities | Single unknown impurity ≤0.1%, total honokiol/magnolol impurities ≤0.5% |
| Solubility | Soluble in ethanol, triglyceride, plant oils; slightly soluble in methanol; insoluble in pure water |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | Pb ≤0.1ppm, As ≤0.1ppm, Cd ≤0.05ppm, Hg ≤0.01ppm |
| Microbiological Index | TPC ≤100cfu/g, Mold & Yeast ≤10cfu/g, Salmonella/E.coli Negative |
| Allergen Status | Non-GMO, Vegan, Gluten-Free, no artificial additives, hormone-free |
| Storage Condition | Nitrogen-filled light-proof vacuum sealed package, store at 2~20℃; avoid light, high heat and air oxidation |
| Unopened Shelf Life | 24 months under standard storage conditions |
| MOQ | 5g sample available; bulk:50g/1kg/5kg/25kg light-proof vacuum packing |
Core Benefits & Functional Mechanism of Dihydrohonokiol-B
Dihydrohonokiol-B is a rare active magnolia lignan with triple core efficacy: potent anti-inflammation, GABA nerve calming, broad-spectrum antibacterial. Orally consumed, it acts on central GABA receptors to calm overactive nerves, relieve chronic anxiety, nervous insomnia and mood irritability; inhibits systemic inflammatory factors to improve long-term low-grade inflammation, joint discomfort and sub-health fatigue. Topically, it blocks histamine release, relieves sensitive skin burning redness, inhibits acne bacteria and malassezia reproduction, controls excess sebum, repairs damaged barrier, improves hormone face, recurring inflammatory acne and oily seborrhea skin.
Native powder is oil-soluble and prone to light oxidation; microcapsule modification achieves water dispersion and better stability. Classic compound schemes: oral Dihydrohonokiol-B + Honokiol + Magnesium Glycinate sleep compound formula; skincare Dihydrohonokiol-B + Panthenol + Glycyrrhetinic acid sensitive acne repair formula.
- Higher anti-inflammatory activity: stronger redness inhibition than conventional magnolia lignans, ideal for severe sensitive inflammation
- GABA nerve soothing: mild sedation without dependence, improves anxiety, light sleep and frequent waking
- Broad-spectrum bacteriostasis: targets acne bacteria and fungi, reduces recurring acne and scalp oiliness
- Dual solubility options: raw crystal for oil formulas; microcapsule adapts to water formulas and oral tablets
- Dual-grade independent production: food grade safe for ingestion, cosmetic grade meets cosmetic filing standards
- Pure plant safe: hormone-free, antibiotic-free, suitable for sensitive groups and long-term daily use

Dihydrohonokiol-B Magnolia Bark Low-Temp Extraction & Purification Process
Full Production Process Steps
- Dried magnolia bark raw material screening, pesticide heavy metal residual pre-inspection
- Dark closed low-temperature ethanol circulating extraction under nitrogen protection
- Macroporous resin staged adsorption to separate Dihydrohonokiol-B from other lignans
- Multiple gradient solvent recrystallization to purify high-purity monomer
- Activated carbon decolorization and membrane filtration to remove plant pigment and macromolecular impurities
- Optional spray drying microcapsule preparation to realize water dispersibility
- HPLC full index inspection, nitrogen-filled light-proof vacuum packaging
GMP herbal extract closed clean workshop, full-process low temperature and light avoidance to prevent lignan oxidation discoloration. Strictly control separation purity, all batches have stable content and solubility, fully comply with global food and cosmetic raw material safety standards.

Factory Supply Capacity & Global Export Certifications
Professional magnolia lignan GMP extraction factory, annual Dihydrohonokiol-B total output reaches 2 tons, regular spot inventory 120kg. Independent constant temperature dark nitrogen storage warehouse prevents oxidative deterioration, stably supplies bulk raw materials to global sleep health oral factories and sensitive acne skincare OEM manufacturers.
Stable Bulk Supply Advantages
- Annual capacity: 2 tons full-spec Dihydrohonokiol-B powder (50%/98%/99%)
- In-stock inventory: 120kg conventional specifications support fast delivery
- Custom water-soluble microcapsule, magnolia multi-lignan compound premix powder
- 4~7 working days bulk delivery, long-term framework order preferential pricing

Batch COA & SDS Full Documents
- ISO22716 & GMP unified production standards for food and cosmetic raw materials
- US FDA GRAS certification, EU food safety + CosIng cosmetic filing eligible
- Dual HALAL & KOSHER certification supporting global religious market exports
- Third-party pesticide residue, heavy metal full testing + complete batch traceability management
- Provide REACH, CPNP documents to support overseas brand registration and customs clearance
6 Core Competitive Advantages of Our Dihydrohonokiol-B
Natural Magnolia Source
Pure magnolia bark extracted, plant-derived, clean label compliant for global natural brands.
Superior Anti-Inflammatory Potency
Higher anti-inflammatory activity than regular honokiol, targeted for severe sensitive redness.
Non-Habit Forming Sleep Aid
GABA gentle calming, no drug dependence, solves anxiety insomnia naturally.
Oil & Water Dual Applicability
Raw crystal for oil phases; microcapsule adapts to water skincare and oral tablets.
Global Dual Compliance
Food/cosmetic dual certification, complete filing materials for EU & US cross-border sales.
Multi-Spec Customization
50%/98%/99% optional, support microcapsule, multi-lignan blended customization.
Request Free Sample & Bulk Quotation
Looking for a reliable supplier of high purity Dihydrohonokiol-B Powder raw material for calming sleep support supplements, anti-anxiety capsules and plant-based functional wellness formulations?
Contact our team today to receive free samples, full COA specifications, global export certification documents and customized bulk pricing for your magnolia bark extract health raw material project.
Main Industrial Application Fields for Dihydrohonokiol-B
Anxiety & Sleep Oral Capsules
Nervous anxiety, insomnia soothing plant nutrition capsules
Chronic Inflammation Nutrient Tablets
Whole-body low inflammation daily conditioning oral tablets
Sensitive Redness Relief Serum
Hormone skin soothing red fading repair essence
Inflammatory Acne Treatment Cream
Recurring inflammatory acne oil control antibacterial cream
Anti-Dandruff Seborrhea Scalp Care
Improve scalp oiliness, itching and flaking care products
Compound Magnolia Lignan Series
Multi-magnolia ingredient internal and external anti-inflammatory system
Strict QC Testing & Official Batch Compliance Documents
Each batch of Dihydrohonokiol-B completes full HPLC monomer content detection, moisture, ignition residue, heavy metals, magnolia pesticide residues, solvent residues and microbial comprehensive testing, fully compliant with ISO22716, FDA GRAS, CosIng global raw material standards.
We provide exclusive batch COA, HPLC chromatogram report, SDS safety data sheet, HALAL/KOSHER/ISO/GMP certification copies, food/cosmetic safety evaluation reports and full batch traceability files, supporting factory audits, global health products and cosmetics registration and customs clearance.
Whole Batch Traceability Management
Unique batch number records all extraction, purification, testing links, permanently traceable for compliance audit
OEM & Custom Formulation Service for Dihydrohonokiol-B
Customizable Service List
- Dihydrohonokiol-B content customization:50%/98%/99%, powder particle fineness adjustment
- Cold water soluble microcapsule powder customization for toner, essence and oral solid drinks
- Magnolia lignan compound premix: Dihydrohonokiol-B + Honokiol + Magnolol blended powder
- Bulk nitrogen-filled light-proof vacuum packaging:50g/1kg/5kg/25kg, customizable private label outer package
- Capsule, tablet, repair cream, essence formula matching guidance and oxidation stability testing
We support long-term framework bulk orders with stable low-impurity indicators. Provide complete compliance documents including batch COA, SDS, safety assessment report, helping cross-border health food and cosmetic brands complete regional filing and customs clearance smoothly.

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