Food and Nutrition Ingredients
Tudca
Tudca (Full name: Tauroursodeoxycholic Acid, CAS:14605-22-2) is a high-purity conjugated bile acid, white crystalline powder with excellent water solubility. It activates bile secretion, accelerates liver toxin metabolism, relieves endoplasmic reticulum stress and chronic inflammation. Food-grade Tudca is widely used in liver detox, hangover relief, fatty liver care, anti-fatigue oral capsules and solid drinks. Cosmetic-grade Tudca is popular for oil control, acne reduction, sebum regulation, sensitive inflamed skin barrier repair skincare.
We supply 98%/99% high-purity Tudca monomer powder and 60% compound bile acid powder. Strictly control animal-derived impurities, heavy metals, residual solvents, protein allergens and microbiology, compliant with FDA GRAS, CosIng, ISO22716, GMP, HALAL & KOSHER. Free testing samples and complete COA & SDS documents are available for brand formula development.
Tauroursodeoxycholic Acid
Water Soluble
Liver Detox Raw Material
HALAL & KOSHER Certified
PRODUCT INTRODUCTION
| Product Name | Tudca, Tauroursodeoxycholic Acid |
| CAS No. | 14605-22-2 |
| Molecular Formula | C₂₆H₄₅NO₇S |
| Molecular Weight | 511.70 g/mol |
| Appearance | White to off-white fine crystalline powder, slight faint special odor, hygroscopic |
| Tudca Assay (HPLC) | 60% / 98% / 99% |
| Related Impurities | Single miscellaneous bile acid ≤0.1%, total impurities ≤0.5% |
| Solubility | Freely soluble in water, methanol; soluble in ethanol; insoluble in vegetable oils |
| pH (1% aqueous solution) | 3.0 ~ 5.0 |
| Loss on Drying | ≤0.4% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | Pb ≤0.1ppm, As ≤0.1ppm, Cd ≤0.05ppm, Hg ≤0.01ppm |
| Microbiological Index | TPC ≤100cfu/g, Mold & Yeast ≤10cfu/g, Pathogens Negative |
| Allergen Description | Low animal protein residue, Non-GMO, Gluten-Free, no artificial additives |
| Storage Condition | Sealed nitrogen-filled light-proof vacuum packaging, store at 2~18℃; avoid high temperature, moisture, light exposure |
| Unopened Shelf Life | 24 months under specified storage environment |
| MOQ | 5g sample order available; bulk:50g/1kg/5kg/25kg moisture-proof vacuum packing |
Core Benefits & Functional Mechanism of Tudca
Tudca is a bioactive conjugated bile acid with triple core effects: liver metabolism promotion, endoplasmic reticulum stress relief, broad-spectrum anti-inflammation. Orally taken, it stimulates liver bile flow, accelerates alcohol, grease and metabolic waste excretion, alleviates hangover discomfort, improves fatty liver burden, repairs liver cell damage caused by staying up late and high oil diet; meanwhile reduces systemic chronic inflammation and delays cell aging. Externally applied, Tudca regulates sebaceous gland lipid secretion, blocks inflammatory factors that trigger acne, improves closed comedones, inflammatory pimples and seborrhea redness, repairs damaged skin barrier, suitable for oily sensitive acne-prone skin.
Tudca is hygroscopic and acid-sensitive; finished products need pH control and sealed preservation. Classic compound collocation: oral Tudca + Silymarin + Glutathione liver protection formula; skincare Tudca + Centella Asiatica + Zinc PCA oil-control anti-acne combination.
- Cholagogue liver detox: boost bile excretion, clear liver toxins, relieve alcohol and greasy liver damage
- ER stress repair: reduce chronic inflammation, improve sub-health fatigue, anti-aging cell maintenance
- Dermatological oil control & acne removal: adjust sebum output, calm inflammatory acne, soothe red sensitive skin
- High water solubility: fully compatible with oral drinks, tablets, essence, toner, mask all water-phase formulas
- Dual-grade independent production: food for oral ingestion, cosmetic grade with stricter allergen limits
- Strong compound synergy: match mainstream liver and skincare ingredients to create multi-effect compound formulas

Tudca Low-Temperature Purification & Refining Manufacturing Process
Full Production Steps
- Qualified bile raw material incoming inspection, heavy metal, microorganism, allergen pre-test
- Closed low-temperature enzymatic hydrolysis reaction under nitrogen inert gas protection
- Multi-step macroporous resin adsorption separation to remove miscellaneous bile acids and protein impurities
- Gradient solvent recrystallization multiple times to enrich high-purity Tudca monomer
- Activated carbon decolorization, ultrafiltration membrane removal of macromolecular allergens
- Vacuum low-temperature freeze drying to obtain crystalline powder, avoid thermal hydrolysis
- HPLC full index testing, moisture-proof light-proof nitrogen vacuum sealed packaging
GMP closed low-humidity purification workshop, full-process low temperature, light shielding and anaerobic operation to prevent Tudca hydrolysis and degradation. Strictly control animal-derived impurities, all batches have stable solubility and purity, fully meet global food and cosmetic raw material safety standards.

Factory Supply Capacity & Global Export Certifications
Specialized bile acid GMP purification production factory, annual Tudca total output reaches 2.8 tons, regular spot inventory 150kg. Independent constant temperature low-humidity dark warehouse prevents moisture absorption and decomposition, stably supplies bulk raw materials to global liver detox health food and oil-acne skincare OEM factories.
Stable Bulk Supply Advantages
- Annual capacity: 2.8 tons full-spec Tudca (60%/98%/99%) powder
- In-stock inventory: 150kg standard specifications support fast shipment
- Custom stable aqueous solution, liver compound blended premix powder
- 4~7 working days bulk delivery, long-term framework order exclusive pricing

Batch COA & SDS Full Documents
- ISO22716 & GMP unified production standards for food and cosmetic raw materials
- US FDA GRAS approved, EU food safety compliance + CosIng cosmetic filing available
- Dual HALAL & KOSHER certification for cross-border religious market exports
- Third-party allergen, heavy metal, solvent full testing + complete batch traceability
- Provide REACH, CPNP supporting documents for overseas brand registration & customs clearance
6 Core Competitive Advantages of Our Tudca
High Purity Low Impurity
Multiple recrystallization purification, miscellaneous bile acids strictly controlled, low animal protein residue.
Dual Liver & Skin Value
Unique two-way application, internal liver detox, external oil-control anti-acne, differentiated advantage.
Multi-Target Anti-Inflammation
Relieve systemic chronic inflammation and skin inflammatory acne, dual anti-inflammatory effect.
Excellent Water Solubility
All water-based formulas compatible, easy to formulate oral liquids, aqueous skincare essence.
Global Cross-Border Compliance
Food/cosmetic dual certification, complete filing documents meet EU & US regulatory requirements.
Multi-Spec Custom Service
60%/98%/99% optional, customized liquid concentration, compound liver raw material blends.
Request Free Sample & Bulk Quotation
Looking for a reliable supplier of high purity Tudca Powder raw material for liver support supplements, detox capsules and daily wellness nutritional formulations?
Contact our team today to receive free samples, full COA specifications, global export certification documents and customized bulk pricing for your liver care health raw material project.
Main Industrial Application Fields for Tudca
Liver Detox Daily Capsules
Stay up late, drinking crowd liver maintenance oral capsules
Fatty Liver Care Nutrient Tablets
High-fat diet crowd bile metabolism conditioning tablets
Hangover Relief Solid Beverage
Water-soluble Tudca instant hangover protection powder drink
Oil Control Anti-Acne Facial Serum
Oily acne skin oil regulating anti-inflammatory essence
Seborrhea Repair Facial Mask
Improve oily redness, closed pores soothing mask
Compound Liver Antioxidant Series
Tudca+Silymarin multi-ingredient liver protection compound line
Strict QC Testing & Official Batch Compliance Documents
Each batch of Tudca undergoes full HPLC content detection, moisture, ignition residue, heavy metals, residual solvents, animal protein allergens and microbial full inspection, fully compliant with ISO22716, FDA GRAS, CosIng global raw material standards.
We provide exclusive batch COA, HPLC chromatogram, SDS safety data sheet, HALAL/KOSHER/ISO/GMP certification copies, food/cosmetic safety evaluation reports and full batch traceability archives, supporting factory audits, global health products and cosmetics registration and customs clearance.
Full Batch Traceability System
Unique batch number records all purification, testing processes, permanently traceable for compliance audit
OEM & Custom Formulation Service for Tudca
Customizable Service List
- Tudca content customization:60%/98%/99%, powder particle fineness adjustment
- Custom concentration stable aqueous solution, pH-adjusted anti-hydrolysis liquid formula
- Liver health compound premix: Tudca + Silymarin + Glutathione blended powder
- Bulk nitrogen-filled light-proof vacuum packaging:50g/1kg/5kg/25kg, customizable private label
- Capsule, tablet, essence, mask formula guidance and stability testing service
We support long-term framework bulk orders with stable purity and controlled allergens. Provide complete compliance documents including batch COA, SDS, safety assessment report, helping cross-border health food and cosmetic brands complete regional filing and customs clearance smoothly.

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