Herbal Extracts
Berberine
Berberine (Berberine Hydrochloride) is natural alkaloid extracted from Coptis chinensis or Berberis aristata root and stem bark. It is bright yellow crystalline powder with bitter taste, slightly soluble in water, soluble in ethanol. We supply HPLC 97% and 98% two purity grades. Non-GMO, vegan, no artificial additives.
Dietary supplement grade, complying with ISO22000, HACCP, GMP, HALAL & KOSHER, meets FDA dietary ingredient requirements. Widely formulated into hard capsules, tablets and compound herbal blends. Stable batches, factory bulk price, free samples and full COA, heavy metal, pesticide residue & microbial reports available.
HPLC 97% / 98%
Non-GMO Vegan
HALAL & KOSHER Certified
Batch COA & Full Test Report
PRODUCT INTRODUCTION
| Product Name | Berberine (Berberine Hydrochloride) |
| Botanical Source | Coptis chinensis / Berberis aristata, root & stem bark |
| CAS Number | 2086-83-1 |
| Assay & Test Method | 97% / 98% HPLC |
| Appearance | Bright yellow crystalline powder, bitter taste |
| Solubility | Slightly soluble in water, soluble in ethanol |
| Loss on Drying | ≤5.0% |
| Heavy Metals | Pb ≤10ppm, As ≤2ppm, Cd ≤1ppm, Hg ≤0.1ppm, dietary supplement compliant |
| Microbiology | TPC ≤10000cfu/g, Yeast & Mold ≤100cfu/g, E.Coli / Salmonella Negative |
| Special Status | Vegan, Non-GMO, no artificial additives |
| Storage Condition | Sealed, cool, dry, dark warehouse, avoid strong light |
| Shelf Life | 24 months for unopened sealed package, protected from light |
| MOQ | 1kg sample order; bulk minimum 25kg export drum |
Core Benefits & Functional Mechanism
Berberine hydrochloride is a natural plant alkaloid extracted from medicinal herbs Coptis chinensis or Berberis aristata. It is widely used in dietary supplement formulations. Our high-purity berberine maintains stable active content, suitable for hard capsule and tablet pressing.
Two purity grades (97% /98% HPLC) are available to satisfy different formulation requirements. The powder has good flowability, easy to blend with other herbal raw materials for compound supplement formulas.
- High purity HPLC tested, consistent active content between batches.
- Dual botanical source options for different traceability requirements.
- Good powder flow property, ideal for capsule filling & tablet compression.
- Non-GMO and vegan, clean label for dietary supplement brand.
- Compatible with multiple herbal extracts for compound blends.
- Light sensitive, must keep sealed and away from strong light.
Tip: Common dosage for capsule formulation: 500mg berberine per capsule. Store finished supplements away from direct sunlight to prevent color fading and active component degradation.
Berberine Production Process
Complete Manufacturing Steps
- Raw herb sorting and impurity removal.
- Raw material cleaning and crushing.
- Water or ethanol solvent extraction.
- Concentrate the extracting liquid.
- Crystallization and recrystallization purification.
- Drying, grinding and particle size sieving.
- Vacuum light-proof sealed packaging with unique batch trace-code.
The whole production is operated in GMP herbal extract workshop. We strictly control heavy metal and pesticide residues. Every batch will be tested for active berberine content, heavy metal, pesticide residue and microbiology, meeting global dietary supplement raw material standards.
Factory Supply Capacity & Global Certifications
We have stable bulk supply of Berberine HCl, HPLC 97% and 98% grades in stock. Serve dietary supplement brands, tablet & capsule manufacturers and herbal ingredient distributors.
Stable Bulk Supply Advantages
- Custom mesh size:80/100 mesh available.
- Two purity options:97% /98% HPLC.
- Compound herbal pre-blend powder service.
- Tiered pricing for long-term framework bulk orders.

Batch COA & SDS Full Documents
- ISO22000 food safety & HACCP GMP herbal clean workshop.
- HALAL & KOSHER global export certifications.
- Third-party full batch active content, heavy metal & microbial testing.
- Full documents support overseas supplement brand registration and customs clearance.
6 Core Competitive Advantages of Our Berberine
Dual Herbal Source
Available from Coptis chinensis or Berberis aristata for different traceability needs.
High HPLC Purity
97% and 98% HPLC grades, stable active content batch to batch.
Good Flowability
Excellent powder property for capsule filling and tablet compression.
Strict Contaminant Control
Rigorous heavy metal and pesticide residue inspection for dietary supplement.
Vegan & Non-GMO
Clean label ingredient suitable for vegan dietary supplement lines.
Full Export Documents
Complete certificates and batch test reports for US & global market clearance.
Request Free Sample & Bulk Quotation
Looking for a reliable supplier of high purity Berberine raw material for blood sugar support supplements, intestinal wellness capsules, metabolic care and herbal functional formulations?
Contact our team today to receive free samples, full COA specifications, global export certification documents and customized bulk pricing for your natural herbal active raw material project.
Main Industrial Application Fields
Dietary Hard Capsules
Main active raw material for berberine capsule supplements
Compressed Tablets
For berberine tablet dietary supplement formulations
Compound Herbal Blends
Combine with other botanical extracts for complex formulas
Functional Pre-mix Powder
Blend raw material for custom supplement pre-mix powder
Herbal Nutritional Supplements
Botanical active ingredient for nutritional supplement lines
OEM Custom Compound Formula
Custom compound blend service for OEM supplement brands
Strict QC Testing & Official Batch Documents
Every batch of Berberine will be tested for berberine content by HPLC, loss on drying, heavy metal, pesticide residue and full microbiological inspection, complying with international dietary supplement raw material safety standards.
We provide exclusive batch-specific COA, HPLC test report, HALAL/KOSHER/ISO22000 certification copies, supporting factory audit, overseas supplement registration and cross-border customs clearance.
Whole Batch Traceability System
Raw herb source, extraction, purification, testing and packaging fully recorded under unique batch-number.
OEM & Custom Formulation Service
Customizable Service Range
- Custom mesh size:80 /100 mesh adjustable.
- Select purity grade: Berberine HCl 97% or 98%.
- Select botanical source: Coptis chinensis or Berberis aristata.
- Herbal multi-ingredient compound pre-blend powder.
- 1kg foil bag /25kg fiber-drum light-proof export packaging.
- Neutral blank export packaging without Focusherb logo, private-label printing available.
- Technical guidance for light-proof storage and formulation tips.
Long-term framework bulk-order preferential-pricing available. Complete COA, active test report, and certification copies support overseas dietary supplement brand registration and customs-clearance.
What’s Berberine?
Berberine is an alkaloid found in the barks, leaves, twigs, rhizomes, roots, and/or stems of various plants, such as the barberry, Oregon grape, and tree turmeric. Traditionally, berberine has been used as an antimicrobial, antiprotozoal, and antidiarrheal agent in Ayurvedic medicine and traditional Chinese medicine.
How does it work?
Berberine is to activate an enzyme inside cells called AMP-activated protein kinase (AMPK). This enzyme plays a key role in regulating metabolism and energy levels and is found in the cells throughout the body.
Berberine also affects various other molecules inside cells, and may even affect which genes are turned on or off, which could help protect against many chronic conditions.
How to buy Berberine?
Please feel free to contact us for any of your needs. You can send an email to admin@focusherb.com or submit your request at the bottom of the page. We will be happy to assist you!
Have any questions?
Let's get in touch!
Contact us if your are thinking of purchasing highquality ingredients, develop new products, or justsolving a manufacturing challenge in your rawmaterials.



















