Herbal Extracts
Vitamin K2(MK7)
Vitamin K2 MK-7 (Menaquinone-7) is the most bioactive subtype of Vitamin K2, produced via liquid deep fermentation of pure Bacillus subtilis strains without chemical synthesis. Our MK7 series strictly controls ≥99% all-trans active isomer with ultra-long blood half-life, delivering dual benefits for bone mineral density and vascular wall health. Focusherb supplies full industrial grades: 0.1%/0.2%/1% standard powder, 1500ppm MCT soluble oil, and 98% high-purity crystal. Microcapsule and liposomal anti-oxidation modifications are available to solve MK7 photo-degradation defects. All batches are verified by HPLC fluorescence detection, complying with USP, FDA GRAS and EU Novel Food standards.
Our MK7 supports bulk wholesale, D3/calcium compound pre-blend OEM, and full private label customization. It is the core raw material for mainstream D3+K2 bone supplements, vascular wellness tablets, elderly bone care and maternal adolescent nutrition formulas.
ISO22000 GMP FSSC22000
FDA GRAS EU Novel Food
All-Trans ≥99% Low Cis-Isomer
Vegan Non-GMO Gluten Free
Full Batch HPLC COA
FDA GRAS EU Novel Food
All-Trans ≥99% Low Cis-Isomer
Vegan Non-GMO Gluten Free
Full Batch HPLC COA
PRODUCT INTRODUCTION
| Product Name | Vitamin K2 MK-7 (Menaquinone 7) |
| CAS Number | 2124-57-4 |
| Production Source | Pure Bacillus Subtilis Liquid Deep Fermentation |
| Available Purity Grades | 0.1%, 0.2%, 1% Powder; 1500ppm MCT Oil; ≥98% Crystal |
| Isomer Control Standard | All-Trans ≥99%, Cis-Isomer ≤0.1% |
| Biological Half-Life | 6–8 Hours (48x Longer Than MK-4) |
| Modified Optional Versions | Microencapsulated, Liposomal, Anti-Oxidation Powder |
| Bulk Packing | 1kg light-proof aluminum foil bag, 25kg food grade fiber drum, neutral export package |
| Certifications | ISO22000, GMP, FSSC22000, Halal, Kosher, Vegan, FDA GRAS, EU Novel Food, HPLC COA |
| MOQ | 1kg sample order, 25kg formal bulk wholesale |
| Shelf Life | 24 months under sealed, light-proof, constant low temp storage |
Bacillus Subtilis Strain Fermentation & Low-Temp Purification Process
We adopt proprietary pure Bacillus subtilis liquid deep fermentation technology, completely eliminating toxic byproducts from chemical synthesis routes. The full production line operates in a light-shielded GMP clean workshop, using low-temperature supercritical CO2 extraction and macroporous resin gradient chromatography to remove inactive cis-MK7 impurities. Optional microcapsule coating solves the core industry pain point of MK7 photo-oxidation and instability. Zero organic solvent residue, fully matching global clean label brand audit requirements.
- High-purity Bacillus subtilis strain liquid fermentation for natural MK7 biosynthesis
- Low-temperature closed extraction to avoid thermal degradation of active trans-isomer
- Gradient chromatography separation strictly controls cis impurity ≤0.1%
- Optional phospholipid liposomal / microcapsule anti-oxidation modification
- Aseptic oxygen-barrier light-proof sealed packaging
- Independent dedicated production line for MCT oil-soluble MK7 liquid grade
Ultra-stable trans-MK7 content with batch difference ≤1%, perfectly matched with Vitamin D3 and calcium compound bone & cardiovascular formulas.
Factory Qualification, Annual Output & Light-Shield Anti-Oxidation Stock
Our vitamin raw material production workshop fully complies with GMP and FSSC22000 global food safety standards, with an independent dedicated fermentation and MK7 purification production line. Every batch completes full HPLC trans-MK7 content testing, heavy metal screening, solvent residue and microbial inspection before delivery.
Stable Production Capacity & Specialized Anti-Oxidation Storage
- Annual total output: 180 tons full series Vitamin K2 MK7 raw materials
- Permanent ready stock: 9–14 tons mixed purity grades, ship within 3–7 working days
- Independent constant temperature oxygen-barrier warehouse to prevent photooxidation discoloration
- Dual parallel fermentation lines support seasonal large bulk rush orders
- ISO22000 Global Food Safety Management System
- GMP 21 CFR Part 111 Nutraceutical Production Standard
- US FDA GRAS & EU Novel Food Export Compliance Dossier
- Halal & Kosher Global Religious Export Certification
- Independent third-party HPLC full batch traceability test system
Every shipment attached official batch COA, HPLC chromatogram spectrum, heavy metal test report and SDS safety data sheet for customs clearance & brand registration.
HPLC All-Trans MK7 COA Spectrum
Core Biological Advantages & MK7 vs MK4 Superiority
Ultra-Long Half-Life, Low Effective Dose
6–8h blood half-life, 48x longer than MK4; only 100–180μg daily nutritional dose works, greatly reduce formulation raw material cost.
Activate Osteocalcin for Bone Density
Promote osteocalcin carboxylation, guide calcium deposition into bone tissue, improve bone mineral density & reduce fracture risk for elderly population.
Inhibit Vascular Calcification
Activate MGP matrix Gla protein, block abnormal calcium sediment on arterial wall, dual bone & cardiovascular protection single raw material.
Golden Synergy Partner with D3 & Calcium
D3 boosts intestinal calcium absorption, MK7 directs calcium into bone; core ingredient for best-selling D3+K2 compound supplement global market.
Pure Microbe Fermented, Vegan Clean Label
Non-synthetic fermentation source, vegan, gluten-free, no chemical solvent residues, fully meet EU & US clean label brand standards.
Match CoQ10 for Comprehensive Vascular Care
Compound with CoQ10 to strengthen endothelial protection, ideal raw material for high-end multi-target cardiovascular wellness formulas.
Have any questions?Let’s get in touch!
Contact us if your are thinking of purchasing highquality ingredients, develop new products, or justsolving a manufacturing challenge in your rawmaterials.
Main Downstream Application Fields
D3+MK7 Bone Health Capsules
Top-selling compound softgel/hard capsule core raw material for adult & senior bone care
Cardiovascular Wellness Tablets
Vascular protection compound formula blended with CoQ10, multi-vitamin minerals
Elderly Osteoporosis Meal Powder
Multi-mineral calcium supplement granular & instant meal replacement powder raw material
Maternal & Teen Bone Growth Nutrition
Pregnancy multi-vitamin, adolescent bone growth nutritional fortifier
Strict QC Full Item Inspection & Batch COA Documents
Every Vitamin K2 MK7 batch executes full-item laboratory testing before shipment: HPLC all-trans MK7 content assay, cis-isomer impurity control, moisture, loss on drying, heavy metals (Pb, As, Hg, Cd), residual solvent, total aerobic bacteria, yeast & mold, coliform & salmonella negative test.
We supply independent third-party authoritative test reports, full HPLC chromatogram spectrum, official COA specification sheet, MSDS safety data sheet, complete compliance dossier to support customer customs clearance, FDA brand registration & factory supplier audit.
Full Batch Traceable QC System
Exclusive unique batch number for every order, full fermentation & lab test data permanently traceable
OEM & Private Label Customization Service
Full Custom Support Range
- Purity custom: 0.1% / 1% powder, 1500ppm oil, 98% high purity crystal
- Stability modification: microencapsulated / liposomal anti-oxidation MK7
- Compound pre-blend: premix with Vitamin D3, calcium citrate, multi-minerals
- Dosage form customization: water dispersible powder, MCT soluble oil liquid
- Finished processing OEM: capsule, tablet, instant solid drink powder
- Neutral light-proof bulk packaging, private label bag & drum design printing
Provide free formulation technical guidance for brand R&D teams, one-stop bone & heart health compound raw material matching solution, support long-term fixed-volume customized supply cooperation.
What’s Vitamin K2(MK7)?
Vitamin K2 (menaquinones) is a slightly lipid soluble vitamin produced by the helpful microbe of intestines. It is a derivative of naphthoquinone and has similar biological activities as phylloquinone. More importantly, it is one of the indispensable and important vitamins in human body.
There are total 14 forms of vitamin K2 (usually noted as MK), which are MK-4, MK-7, MK-8, MK-9, etc. Among them, the synthetic MK-4 and natural MK-7 are the most common forms of vitamin K2. Both of them play important roles in bone and cardiovascular health.
The bioactivities of vitamin K2 are related to the length of its side chain. The longer the side chain is, the higher the biological activities are. Vitamin K2 with long side chain is also easier to be absorbed and can exists in the blood for a longer time. Vitamin k2-7 (MK-7) is the most unique in the vitamin K2 family and has been proved to have the highest bioavailability. It has a long half-life in the blood after oral intake, thus it can play its benefits for a long period of time.
Product Features
Pure natto fermentation, natural, green and safe
Completely natural trans- vitamin K2 (MK-7)
Reasonable medium formula design, multi factor dynamic control technology to ensure high expression of bacteria
Non-organic solution extraction, physical separation and concentration technology, no secondary pollution
Long lasting and stable activity
Why choose FocusHerb Harpagoside?
Focusherb has been focusing on the production and research and development of plant extracts for many years. With a competitive price, and the price of the test material provided by the strict and strict independent testing, please contact us now.
Just send an email toadmin@xafhbio.com , or ask your needs at the bottom, we are here for you!
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Have any questions?
Let's get in touch!
Contact us if your are thinking of purchasing highquality ingredients, develop new products, or justsolving a manufacturing challenge in your rawmaterials.
