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Cosmetic Ingredients

Cosmetic Ingredients

Wheat Germ Extract Spermidine


  • Product Name: Spermidine from wheat germ powder
  • Specs: 0.2%, 0.5%, 1%
  • Original Country: China
  • Quality: 100% vegan & without additives
  • Shelf Life: 24 months

PRODUCT INTRODUCTION

What’s Spermidine?

Spermidine is a naturally occurring polyamine characterized by the presence of two or more primary amino groups. It is widely found in ribosomes and living tissues and plays a vital role in cellular function and survival. Studies have shown that spermidine can extend lifespan in fungi, nematodes, insects, and rodents, highlighting its potential longevity benefits.

In humans, spermidine is synthesized from its precursor putrescine and is a key component in the production of spermine, another essential polyamine. It supports cellular health, growth, and maintenance and is essential for overall biological processes.

One of the most notable functions of spermidine is its role as a potent activator of autophagy – a natural cellular process that removes damaged components and promotes cell renewal. By stimulating autophagy, spermidine helps restore cellular activity and extend lifespan. Recent studies suggest that increasing dietary spermidine intake may reduce all-cause mortality, particularly by supporting cardiovascular health.

The Specification of Spermidine

Product Name Spermidine
Botanical Source Triticum aestivum
Part Used Germ
Specs 0.2%, 0.5%, 1% GC
Appearance Light yellow to yellow powder
Packaging By 25kgs/Drum, inner by plastic bag
Odor Characteristic
Storage Stored in cool and dry places. Keep away from strong light and heat
Shelf Life 24 months
Spermidine is a natural polyamine

The Benefits of Spermidine

Spermidine has gained significant attention in recent years due to its potential health benefits. As a naturally occurring polyamine, it has been extensively studied for its role in various aspects of human health. However, while research is promising, it remains in the early stages, and many potential benefits have yet to be fully confirmed in humans.

Emerging evidence suggests that spermidine may support cardiovascular health, enhance fertility, and slow the aging process. It is known to activate autophagy, a cellular renewal process that helps extend lifespan, combat cellular aging, and maintain healthy cells, skin, and brain function.

Spermidine itself is the active ingredient in spermidine supplements.

Extend Life and Reduce Risk of Disease

Spermidine, much like fasting, activates protein deacetylation and autophagy, promoting healthy DNA function and the removal of senescent and toxic cells. Research suggests that spermidine supplementation may help lower the risk of various health conditions, including cancer, cardiovascular disease, metabolic disorders, and neurodegenerative diseases.

Notably, strong evidence links spermidine to improved cardiovascular health. Studies on aged mice have shown that spermidine supplementation enhances heart structure and function, contributing to better overall heart health. These benefits are further associated with metabolic improvements, as spermidine helps restore mitochondrial structure and function, optimizing energy production and cellular efficiency.

Anti-inflammatory and Immune-boosting Properties

Preclinical laboratory trials suggest that spermidine reduces inflammation and slows cellular and tissue aging. A 2017 study further demonstrated its antioxidant properties, showing that spermidine protects against oxidative stress by reducing the accumulation of reactive oxygen species (ROS) within cells. These harmful free radicals contribute to chronic inflammatory conditions such as rheumatoid arthritis, ischemic heart disease, and various lung, kidney, and liver diseases.

While autophagy activation remains spermidine’s primary mechanism for promoting longevity, research suggests additional benefits. Studies indicate that spermidine also exhibits anti-inflammatory properties and plays a role in lipid metabolism, cell growth, proliferation, and apoptosis (programmed cell death), further contributing to overall health and longevity.

spermidine autophagy

Why Choose Focusherb Spermine Capsules?

Your cellular health directly impacts your overall well-being and disease risk. Incorporating spermidine-rich foods—such as wheat germ, whole grains, soybeans, cruciferous vegetables, nuts, beans, and peas—into your diet is a natural way to support cell function and longevity.

For additional support, spermidine supplements can help protect cells from age-related decline, promoting optimal energy levels and overall vitality as part of a healthy lifestyle.

GREEN LABEL

Green Label

Vegan & cruelty-free
Maximum avoidance of any additives and excipients
If additives are used, only valuable natural substances
Maximum avoidance of chemical solvents in extracts
Filled in in pharmaceutical quality (GMP, ISO 22000:2018 and HACCP)
Only vegan capsule shells: 100% free of carrageenan and PEG
Packaging is free of plasticizers
Free of any unwanted additives such as magnesium stearate, gelatin, titanium dioxide, silicon dioxide, nanoparticles (without legal exceptions), genetic engineering, artificial colors and flavors, added sugar & sweeteners
Each batch is laboratory tested

Quality & Purity

Focusherb spermine capsules contain an ideal dose of a special wheat germ powder (Triticum sativum) and are produced in a pharmaceutical factory in Germany. These capsules are ultra-pure and 100% plant-based.

At Focusherb, we care deeply about the quality of our products. Our products are manufactured in carefully, rigorously tested facilities and meet the highest quality standards. When developing our products, we pay special attention to their tolerability and bioavailability.

QUALITY & PURITY

Our Promise

VEGAN & HYPOALLERGENIC
RAW MATERIALS & MANUFACTURING

Vegan& Hypoallergenic 

We focus on the essentials, process only premium raw materials, and completely avoid unnecessary additives. All of our products are vegan and hypoallergenic. All raw materials are filled into vegan cellulose shells.

Raw Materials & Manufacturing

For our products, we search the world for the highest quality raw materials – free from contamination, rich in ingredients, and optimal in their effect. Only when our demands are fully met do we include a product in our range?

Pharmacy Quality

We do everything every day to ensure the product quality, purity, and safety of our products for you. Our products are carefully manufactured in strictly tested facilities in China. At all steps, we adhere to the strict HACCP quality standards.

FAQs

What is spermidine?

Spermidine is a natural polyamine found in all cells in the body.

What does autophagy mean?

Autophagy is the term used to describe the process in which old/damaged cells are broken down and reused to create new, healthy cells.

Does Spermidine contain actual sperm?

No – although it’s a common question. That being said, Spermidine is found in semen, as it is present in all body cells.

What is it good for?

Spermidine has been linked with multiple health benefits including prolonged lifespan due to its anti-inflammatory and antioxidant properties, as well as its ability to boost cell renewal and autophagy.

Which foods are highest in Spermidine?

There are many plant-derived foods with moderate to high levels of Spermidine; these include Soya beans, Wheatgerm, Vegetables (peas and mushrooms are both excellent sources) as well as cruciferous veg such as cauliflower or broccoli, Cheese (particularly cheddar, brie, parmesan, and gouda), Fruits (mangos and bananas particularly so).

Should I supplement with Spermidine?

Spermidine is a naturally occurring product so there are minimal risks associated with taking it in supplement form. Given the benefits it can have on the body and boosts cell renewal, immunity, and promotes antiaging, it’s certainly a recommended supplement on our list! That being said, if you have any doubts or existing health conditions, please check with your health provider first.

What is the recommended dosage for Spermidine?

6mg per day is an average dose, but it would be best to check with your health provider if you aren’t sure.

Does Spermidine have side effects?

There are no known side effects associated with taking Spermidine supplements.

Is Spermidine vegan friendly?

Yes, Spermidine is vegan-friendly.

How does spermidine work?

Spermidine has been characterized as a natural autophagy inducer. Autophagy is a process by which cells get rid of parts that are no longer needed or don’t work right, helping cells stay healthy and promoting longevity. Spermidine has been shown to block several enzymes that negatively control autophagy and may be as powerful as rapamycin, an FDA-approved immunosuppressant with strong autophagy-stimulating effects.

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