Cosmetic Ingredients
5-ALA Powder
5-ALA (5-Aminolevulinic Acid Hydrochloride, CAS:5451-09-2) is a natural hydrophilic active cosmetic raw material. White crystalline powder, easily soluble in water. After penetrating the epidermis, it participates in skin endogenous porphyrin metabolism and produces mild photobiomodulation effects. It effectively repairs UV-induced photoaging, evens uneven skin tone and refines rough texture, widely applied in brightening essence, anti-photoaging serum, repair mask and mild professional skin renewal products.
We supply cosmetic grade 99% high purity 5-ALA HCl crystal powder, customized stable aqueous solution available upon request. Strict control of related impurities, heavy metals and microbial limits, fully compliant with CosIng, ISO22716, GMP, HALAL & KOSHER cosmetic standards. Free formulation samples and complete COA & SDS documents can be provided for brand R&D.
5-ALA
5-Aminolevulinic Acid HCl
99% Cosmetic Grade
Water Soluble Active
HALAL & KOSHER Certified
5-Aminolevulinic Acid HCl
99% Cosmetic Grade
Water Soluble Active
HALAL & KOSHER Certified
PRODUCT INTRODUCTION
| Product Name | 5-Aminolevulinic Acid Hydrochloride (5-ALA), Cosmetic Grade |
| CAS No. | 5451-09-2 |
| Molecular Formula | C₅H₉NO₃·HCl |
| Molecular Weight | 167.59 g/mol |
| Appearance | White to off-white fine crystalline powder, odorless |
| Assay (HPLC) | ≥99.0% |
| Related Substances | Single unknown impurity ≤0.1%, total impurities ≤0.5%V |
| Solubility | Freely soluble in water; slightly soluble in methanol; insoluble in oil phase |
| pH (1% aqueous solution) | 3.0 ~ 4.5 |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | Pb ≤0.1ppm, As ≤0.1ppm, Cd ≤0.05ppm, Hg ≤0.01ppm, cosmetic grade compliant |
| Microbiology | TPC ≤100cfu/g, Yeast & Mold ≤10cfu/g, Pathogens Negative |
| Allergen Status | Non-GMO, no parabens, no artificial fragrances |
| Storage Condition | Sealed moisture-proof & light-proof vacuum packaging, 2~8℃ cool warehouse, avoid moisture, strong light & high temperature |
| Unopened Shelf Life | 24 months under recommended storage environment |
| MOQ | 5g sample order, 50g / 1kg / 5kg / 25kg bulk moisture-proof vacuum packaging |
Core Benefits & Functional Mechanism of 5-ALA
5-ALA is a hydrophilic endogenous precursor substance. After percutaneous absorption, it participates in heme biosynthesis pathway and generates protoporphyrin IX, producing mild photobiomodulation effects. It activates skin self-repair mechanism against UV damage, accelerates orderly metabolism of aged keratinocytes, promotes microcirculation, fades dull complexion and improves uneven tone caused by photoaging. It strengthens barrier resilience and softens rough, dry skin texture.
5-ALA is water-soluble and acidic; formulators need to control system pH and add antioxidant & chelating agents to improve solution stability. Recommend compounding with panthenol, centella asiatica extract, hyaluronic acid to strengthen barrier repair. Suitable for daytime anti-light aging and nighttime brightening series.
- Anti-photoaging: Activate skin self-repair to relieve UV-induced oxidative damage
- Skin brightening: Improve yellowness, dullness and uneven skin tone
- Refine rough texture: Promote regular keratin turnover, smooth dry bumpy skin
- Support barrier health: Improve microcirculation, enhance skin resistance
- Good water solubility: Easy to formulate into essence, toner, mask, ampoule
- Flexible options: Pure crystal powder & customized stable aqueous solution available
Formulation Tip: Recommended dosage 0.05%–0.3% in finished skincare products; control formula pH 3.5–5.0; add EDTA and suitable antioxidants to enhance stability; finished products adopt amber light-proof bottles, avoid long-term high temperature storage.
5-ALA Low-Temp Synthesis & Multi-Stage Purification Process
Full Manufacturing Steps
- High purity raw material screening, heavy metal and residual solvent pre-inspection
- Closed low-temperature directional synthesis under inert gas protection
- Multi-stage solvent extraction and recrystallization to separate related impurities
- Activated carbon decolorization to remove colored by-products
- Vacuum low-temperature crystallization to obtain high purity 5-ALA crystal powder
- Optional configuration of stable aqueous solution with pH adjustment and stabilizer addition
- HPLC full detection of content and impurities, moisture-proof light-proof vacuum sealed packaging
GMP water-soluble active ingredient closed clean workshop, whole-process low-temperature & light-shielded operation, strictly control related impurities and color stability, batches maintain consistent solubility, fully meet global cosmetic raw material safety standards.
Factory Supply Capacity & Global Export Certifications
Specialized water-soluble cosmetic active ingredient GMP factory, annual 5-ALA total output reaches 6 tons, 500kg regular spot inventory, independent constant temperature moisture-proof dark warehouse to prevent degradation, stable bulk supply for global brightening & anti-photoaging skincare OEM brands.
Stable Bulk Supply Advantages
- Annual production capacity: 6 tons cosmetic grade 99% 5-ALA powder series
- Ready spot stock: 500kg standard grade for fast delivery
- Custom stable aqueous solution concentration, pre-blended repair compound raw material
- 4~7 working days fast delivery for standard bulk orders, long-term framework preferential pricing
Batch COA & SDS Full Official Documents
- ISO22716 / GMP Cosmetic Raw Material Production Specification
- EU CosIng filing compliant, US FDA cosmetic ingredient safety certified
- HALAL & KOSHER dual global religious export certification
- Third-party heavy metal, impurity & safety testing, full batch traceability system
- REACH, CPNP cosmetic registration supporting documents
6 Core Competitive Advantages of Our 5-ALA
99% High Purity Low Impurity
Multi-stage recrystallization purification, strictly control related substances, stable color and dissolution performance.
Targeted Anti-Photoaging Activity
Natural photobiomodulation active, suitable for daytime UV defense & post-sun repair series.
Excellent Water Solubility
Fully soluble in aqueous formula, compatible with essence, toner, mask and ampoule systems.
Dual Supply: Powder & Aqueous Solution
Supply pure crystal powder, support customization of stabilized ready-to-use aqueous solution.
Global Cosmetic Regulatory Compliant
CosIng & FDA compliant, HALAL/KOSHER dual certification, full filing documents for cross-border brands.
Custom Compound Formulation Support
Custom repair premix, moisture-proof packaging, aqueous solution stabilization & formulation technical guidance.
Request Free Sample & Bulk Quotation
Looking for a reliable supplier of high purity 5-ALA Powder raw material for plant growth regulators, skin brightening cosmetics and healthcare nutritional supplements?
Contact our team today to receive free samples, full COA specifications, global export certification documents and customized bulk pricing for your 5-Aminolevulinic Acid raw material project.
Main Industrial Application Fields for 5-ALA
Anti-Photoaging Day Serum
Daytime defense essence against UV oxidative skin damage
Brightening Repair Night Essence
Improve dull yellowness, uniform facial uneven tone
Repair & Brightening Facial Mask
Post-sun recovery, relieve dry and dull skin
Professional Mild Skin Renewal Ampoule
Suitable for beauty salon gentle conditioning line
Moisturizing Brightening Toner
Daily basic care to improve rough and tired skin
Sensitive Skin Barrier Care Series
Match soothing extracts to enhance skin self-repair ability
Strict QC Testing & Official Batch Compliance Documents
Each 5-ALA batch undergoes full HPLC testing for main content, related impurities, loss on drying, ignition residue, heavy metals, residual solvents and complete microbial inspection, fully compliant with ISO22716, CosIng and FDA cosmetic raw material standards.
We provide exclusive batch COA, HPLC spectrum test report, SDS safety data sheet, HALAL/KOSHER/ISO/GMP certification copies, cosmetic safety assessment report, full batch traceability records, supporting cosmetic factory audits, global cosmetic registration and customs clearance.
Full Batch Traceability System
Unique batch number, complete synthesis, purification and testing records, permanent traceability for cosmetic compliance audits
OEM & Custom Formulation Service for 5-ALA
Customizable Service Range
- 99% cosmetic grade 5-ALA crystal powder particle fineness customization
- Custom concentration stable aqueous solution, add stabilizer & pH adjustment
- Pre-blended repair premix: 5-ALA + Panthenol + Centella Asiatica Extract + HA
- Bulk moisture-proof light-proof vacuum packaging: 50g /1kg /5kg /25kg, customizable outer label
- Essence, mask, ampoule formulation technical guidance, stability testing support
Support long-term framework bulk orders with stable purity and low impurity indicators, supply complete regulatory documents including batch COA, SDS, test reports and certification copies to help cross-border cosmetic brands complete regional filing and customs clearance.
How to buy 5-ALA ?
Please feel free to contact us for any of your needs. You can send an email to admin@focusherb.com or submit your request at the bottom of the page. We will be happy to assist you!
Have any questions?
Let's get in touch!
Contact us if your are thinking of purchasing highquality ingredients, develop new products, or justsolving a manufacturing challenge in your rawmaterials.
