Cosmetic Ingredients
Climbazole Powder
Climbazole (INCI) is imidazole anti-fungal crystalline powder, specialized cosmetic-only raw material targeting Malassezia fungus. It inhibits ergosterol synthesis to remove dandruff and relieve scalp itch, with excellent stability against metal ions & no yellow discoloration. Double function as anti-dandruff active + mild preservative. HPLC purity 98%-99.2%, strictly tested for impurities, heavy metals and microorganisms, fully compliant with EU CosIng & SCCS cosmetic regulations.
We supply bulk wholesale, anti-dandruff compound blending and neutral OEM packaging. Widely applied in anti-dandruff shampoo, scalp essence, seborrhea repair hair care products. Complete SDS, COA and CPNP/REACH registration documents provided for cross-border cosmetic brands.
Cosmetic Only Grade
ISO22716 GMP
EU CosIng SCCS Approved
CPNP REACH Support
Batch COA & SDS Attached
Non-Yellow Formula Stable
ISO22716 GMP
EU CosIng SCCS Approved
CPNP REACH Support
Batch COA & SDS Attached
Non-Yellow Formula Stable
PRODUCT INTRODUCTION
| Product Name | Climbazole Powder – Cosmetic Anti-Dandruff Active |
| CAS No. | 38083-17-9 |
| Molecular Formula | C₁₅H₁₇ClN₂O₂ |
| Molecular Weight | 292.76 |
| Appearance | White to off-white fine crystalline powder, odorless |
| Assay (HPLC) | 98% / 99% / 99.2% (customizable) |
| Impurity Control | Heavy metals below USP/EP limits; residual solvents within ICH Q3C; p-chlorophenol ≤100ppm |
| Solubility | Slightly soluble in ethanol, propylene glycol & surfactants; pre-dissolution SOP available |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | Pb ≤10ppm, As ≤2ppm, Cd ≤1ppm, Hg ≤0.1ppm (EU cosmetic compliant) |
| Microbiological Index | TPC ≤1000cfu/g, Yeast & Mold ≤100cfu/g; |
| Storage | Sealed, cool & dark place; avoid prolonged high temperature |
| Shelf Life (unopened) | 24 months under proper storage |
| MOQ | 1kg R&D sample; 25kg bulk wholesale |
| Source | Synthetic (non-plant, consistent batch-to-batch) |
| Particle Size | 100 mesh / 200 mesh crystalline powder (custom) |
| Available Grade | Cosmetic Grade only (for topical formulations) |
| Certifications | ISO22716, GMP, EU CosIng, SCCS assessed, REACH/CPNP support, Halal, Kosher |
| Packaging Options | 1kg foil bag, 25kg fiber drum, neutral private labeling available |
Formulation Benefits: Why Climbazole Belongs in Your Anti-Dandruff Line
Targeted efficacy in rinse-off systems. Climbazole inhibits ergosterol synthesis in Malassezia yeasts, making it a trusted active for anti-dandruff shampoos. Its metal-ion stability prevents yellowing – a common headache with other imidazoles – preserving formula aesthetics in clear and pearlescent systems.
Synergistic compounding: Works exceptionally well with Piroctone Olamine (broad-spectrum boost), Salicylic Acid (for seborrhea scalp serums), and Zinc Pyrithione (cost-effective blends). We provide compatibility data upon request.
- Non-yellowing: Purified to remove trace metals – transparent formulas stay clear.
- Dual function: Active anti-dandruff + mild preservative – reduce your raw material SKUs.
- Mild profile: Lower irritation compared to Ketoconazole – suitable for frequent-use shampoos.
- Easy processing: Dissolves in surfactants with our pre-mix SOP (40-60°C PG/Ethanol).
- Globally accepted: EU CosIng listed, SCCS assessed – supports your international filings.
Formulation Tips: For optimal dissolution, pre-mix Climbazole with Propylene Glycol (1:2 ratio) at 50°C before adding to the surfactant phase. Avoid prolonged heating above 80°C to maintain active integrity.
Consistent Quality via Controlled Synthetic Process
Manufacturing Highlights
- Closed-loop synthesis with precise temp/pressure control for high yield
- Multi-stage solvent extraction to eliminate intermediate impurities
- Recrystallization purification achieving ≥99% HPLC purity
- Low-temperature vacuum drying – prevents thermal decomposition
- Vibratory sieving for uniform particle size (100/200 mesh)
- 100% batch testing (HPLC, heavy metals, residual solvents) before release
- Aseptic light-proof packaging with unique batch traceability code
Operated under ISO22716 GMP guidelines. Every batch delivers consistent dissolution and color performance, critical for large-scale shampoo production.
Supply Chain Stability & Export Readiness
55 tons annual capacity with 1.8–5 tons ready stock ensures you never face production halts. We maintain dedicated dark warehouses to preserve active potency. Bulk tier pricing available for long-term framework agreements.
Logistics & Compliance Advantages
- Lead time: 3–7 working days (sample & bulk)
- Non-hazardous classification – smooth customs clearance
- Full dossier package: COA, MSDS, SCCS, Stability data
- REACH / CPNP filing support documentation
- Neutral or private-label packaging options
Batch COA, SDS & SCCS
Full Documentation Ready
- ISO22716 GMP certified cosmetic workshop
- EU CosIng listed & SCCS safety assessed
- Halal & Kosher certified for global brand acceptance
- Third-party testing available upon request
6 Reasons to Source Climbazole from Focusherb
55T Capacity + 5T Stock
No supply gaps. We ship bulk orders within 3–7 days, keeping your production line running.
Zero Yellowing Guarantee
Proprietary metal-ion removal ensures crystal-clear shampoos – no customer complaints about discoloration.
Full Dossier Per Batch
COA, SDS, and SCCS attached. Avoid customs delays and regulatory fines with our documentation.
R&D Formulation Support
Free dissolution SOPs and compatibility data for ZPT/PO/Salicylic acid blends – save weeks of lab work.
Non-Hazardous Shipping
Not DG-classified. Standard air/sea freight with simple customs paperwork – lower logistics costs.
Compliance Risk Mitigation
We provide a “Claim Compliance Checklist” to keep your Shopify/FDA listings safe from “medical claim” bans.
Request Free Sample & Bulk Quotation
Looking for a reliable supplier of high purity Climbazole Powder raw material for anti-dandruff shampoo, scalp care lotion, anti-fungal skincare and cosmetic preservative formulations?
Contact our team today to receive free samples, full COA specifications, global export certification documents and customized bulk pricing for your anti-fungal cosmetic raw material project.
Where Cosmetic Manufacturers Use Climbazole
Anti-Dandruff Shampoos
Core active for rinse-off hair care
Scalp Serums (Leave-on)
≤0.2% for seborrhea care
Oil-Control Conditioners
Long-lasting anti-itch formulas
Anti-Flaking Body Washes
Skin microbiome-friendly additives
Batch Traceability & Full Documentation Package
Every batch of Climbazole undergoes rigorous QC: HPLC assay, drying loss, residue on ignition, heavy metals (Pb/As/Cd/Hg), residual solvents, and microbial limits. All results meet or exceed EU cosmetic standards.
With every shipment, you receive:
- Batch-specific COA (Certificate of Analysis)
- 16-section MSDS (Material Safety Data Sheet)
- SCCS safety assessment summary
- Stability data (accelerated & long-term)
- EU CPNP / REACH filing support documents
Whole Batch Traceability System
Synthesis, purification, testing, packaging all recorded by unique batch number
Tailored OEM Solutions for Your Brand
Customization Options
- Particle size: 100/200 mesh crystal (adjustable)
- Purity grades: 98% / 99% / 99.2% HPLC
- Premix blends: Climbazole + Piroctone Olamine / ZPT / Salicylic Acid
- Packaging: 1kg foil bag / 25kg drum with private label
- Neutral export packaging (no brand logo) available
- Formula troubleshooting: Our lab assists with dissolution and stability trials
Long-term supply agreements with fixed pricing available. We support your overseas brand registration with full regulatory documentation.
Why Cosmetic Manufacturers Choose Focusherb Climbazole
For Purchasing Managers:
Worried about supply gaps? Our 55-ton annual capacity + 5-ton ready stock ensures 24/7 availability. We ship within 3–7 working days. Climbazole is classified as non-hazardous chemical (not in DG catalog) – smooth DHL/UPS air freight with proper shipping docs.
For R&D Chemists:
Tired of yellowing shampoos? Our proprietary purification process removes trace metal ions, ensuring zero discoloration in transparent systems even after 6 months. We provide pre-dissolution SOPs (PG/Ethanol 40-60°C) and compatibility data with ZPT/Piroctone Olamine/Salicylic Acid.
For Brand & Compliance Teams:
Avoid FDA/Amazon bans. Every batch includes SCCS safety assessment, COA, and MSDS. We also supply a “Claim Compliance Checklist” to help you navigate EU CPNP, FDA MOCRA, and ASEAN labeling requirements.
How to buy Climbazole Powder ?
Please feel free to contact us for any of your needs. You can send an email to admin@focusherb.com or submit your request at the bottom of the page. We will be happy to assist you!
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