Products

Cosmetic Ingredients

Cosmetic Ingredients

Retinol


Retinol (Vitamin A Alcohol, CAS:68-26-8) is the gold-standard anti-aging retinoid raw material. It exists as pale yellow crystalline powder, fat-soluble, converts to retinoic acid inside skin cells to activate collagen synthesis and accelerate keratin turnover. It delivers powerful anti-wrinkle, pore refining, light spot fading and skin tightening effects, widely used in high-end anti-aging serums, night creams, pore care and body firming lotions.

We supply 3 standard grades: 99% pure Retinol powder, 10%/20% oil-soluble Retinol stock liquid, microcapsule slow-release Retinol for sensitive skin lines. All batches adopt full low-temperature oxygen-isolated production to control peroxide value & oxidation impurities, fully compliant with CosIng, FDA, ISO22716, GMP, HALAL & KOSHER. Free samples and full COA/SDS documents provided.

Retinol
Vitamin A Alcohol
99% High Purity
Oil Soluble Anti-Aging
HALAL & KOSHER Certified

PRODUCT INTRODUCTION

Complete Technical Specification (Retinol / Vitamin A Alcohol)


Product Name Retinol, Vitamin A Alcohol
CAS No. 68-26-8
Molecular Formula C₂₀H₃₀O
Molecular Weight 286.45 g/mol
Appearance (Pure Powder) Pale yellow fine crystalline powder, characteristic faint vitamin odor
Appearance (Oil Solution) Light yellow transparent oily liquid, stable in plant oil carrier
Retinol Content (HPLC) Powder ≥99.0%; Oil:10% / 20% ±0.5%
Peroxide Value ≤5.0 meq/kg (Strict anti-oxidation control)
Solubility Insoluble in water; soluble in ethanol, vegetable oil, ester cosmetic oil phases
Melting Point 62 ~ 64℃
Moisture Content ≤0.2%
Heavy Metals Pb ≤0.1ppm, As ≤0.1ppm, Cd ≤0.05ppm, Hg ≤0.01ppm, cosmetic grade compliant
Microbiology TPC ≤100cfu/g, Yeast & Mold ≤10cfu/g, Pathogens Negative
Allergen Status No parabens, no artificial fragrances, non-GMO
Storage Condition Sealed light-proof vacuum packaging, -5~15℃ cool warehouse, avoid light, heat & air contact
Unopened Shelf Life 24 months under low temp light-proof storage
MOQ 5g sample order, 50g / 1kg / 5kg / 25kg bulk vacuum packaging

Core Benefits & Functional Mechanism of Retinol


Retinol penetrates epidermis and converts into retinoic acid inside keratinocytes. Two core anti-aging pathways: 1. Activate fibroblast gene expression to boost collagen & elastin synthesis, fill fine lines and lift sagging skin; 2. Accelerate orderly keratin exfoliation, unclog pores, accelerate melanin metabolism to fade post-acne marks and photoaging pigmentation. Long-term use refines rough texture, shrinks enlarged pores and restores smooth translucent skin.

Retinol carries mild irritation risk for sensitive skin; we recommend compounding with panthenol, centella asiatica extract, niacinamide and squalane to soothe barrier irritation. Microcapsule encapsulated Retinol slows release to cut irritation for sensitive skin series. Avoid pairing with high-concentration acid ingredients to prevent over-stimulating skin.

  • Boost collagen & elastin: fill dry lines, static wrinkles, improve sagging loose skin contour
  • Speed up keratin turnover: dissolve blackheads, closed comedones, refine enlarged oily pores
  • Fade light pigmentation: accelerate melanin shedding, fade sun spots, acne marks and dull yellow tone
  • Smooth rough aging texture: improve chicken skin, uneven bumpy skin on face & body
  • Sebum regulation: balance oily secretion, long-term control shine for combination & oily skin
  • Multi-formula compatibility: pure powder, oil stock liquid, slow-release microcapsule 3 options for all anti-aging lines

Formulation Tip: Night skincare only, recommended dosage 0.1%-0.3% (retinol basis); finished products must use amber light-proof bottles, add BHT/Vitamin E antioxidant stabilizers; sensitive skin match centella & panthenol to reduce irritation.

Retinol collagen synthesis keratin renewal mechanism diagram

Retinol Low-Temp Oxygen-Isolated Synthesis & Purification Process


Full Manufacturing Steps

  1. High-purity vitamin precursor raw material screening, heavy metal & impurity pre-inspection
  2. Closed low-temperature catalytic synthesis, full nitrogen protection to block oxidation
  3. Multi-stage recrystallization purification, remove retinal oxidation impurities & residual solvents
  4. Vacuum low-temp drying to obtain 99% pure Retinol crystal powder
  5. Oil dissolution / microcapsule embedding: dissolve in plant oil carrier or wrap with biodegradable shell
  6. HPLC detection for retinol content, peroxide value, full impurity screening
  7. Light-proof vacuum nitrogen-filled packaging, constant temperature dark storage

GMP oil-soluble active ingredient clean production line, whole-process nitrogen anti-oxidation closed operation, strictly control peroxide value, stable batch activity, no discoloration failure during finished product shelf life, meet global cosmetic raw material safety standards.

Factory Supply Capacity & Global Export Certifications


Specialized lipophilic anti-aging active ingredient GMP factory, annual Retinol total output reaches 15 tons, 1.2 tons regular spot inventory, independent constant temperature dark nitrogen warehouse to prevent oxidative failure, stable bulk supply for global high-end anti-aging skincare OEM brands.

Stable Bulk Supply Advantages

  • Annual production capacity: 15 tons 99% Retinol powder & oil solution series
  • Ready spot stock: 1.2 tons standard 3 grades for fast delivery
  • Custom oil carrier, microcapsule wall material, pre-blended soothing anti-aging compound
  • 4~7 working days fast delivery for standard bulk orders, long-term framework preferential pricing
halal

Batch COA & SDS Full Official Documents

  • ISO22716 / GMP Cosmetic Raw Material Production Specification
  • EU CosIng filing compliant, US FDA cosmetic ingredient safety certified
  • HALAL & KOSHER dual global religious export certification
  • Third-party irritation & heavy metal safety testing, full batch traceability system
  • REACH, CPNP cosmetic registration supporting documents

6 Core Competitive Advantages of Our Retinol


99% High Purity Low Oxidation

Full nitrogen closed synthesis, peroxide value strictly controlled ≤5meq/kg, stable activity without discoloration.

3 Grades One-Stop Supply

Pure powder, oil soluble stock liquid, slow-release microcapsule to match regular & sensitive anti-aging lines.

Custom Low-Irritation Formula

Pre-blended compound with centella & panthenol, microcapsule wrapping to reduce skin irritation risk.

Perfect Lipophilic Compatibility

Fully soluble in all cosmetic ester & plant oil phases, no precipitation in cream, serum & night lotion.

Global Cosmetic Regulatory Compliant

CosIng & FDA approved, HALAL/KOSHER certified, full filing docs for EU/US cross-border brands.

Full OEM Custom Support

Custom oil carrier concentration, microcapsule specification, light-proof vacuum packaging & formulation technical guidance.

Request Free Sample & Bulk Quotation

Looking for a reliable supplier of cosmetic grade Retinol raw material for anti-aging serums, anti-wrinkle creams, facial essences and skin renewal skincare formulations?

Contact our team today to receive free samples, full COA specifications, global export certification documents and customized bulk pricing for your anti-aging cosmetic raw material project.

Get Free Sample & Quote

Main Industrial Application Fields for Retinol


Anti-Aging Night Serum

Classic retinol anti-wrinkle essence, fade fine lines & large pores

Repair Night Cream

Overnight collagen boost, improve sagging & dull aging skin

Pore Refining Skin Care

Oil control toner, exfoliating lotion for blackhead & closed acne

Body Firming Lotion

Improve chicken skin, rough arm & leg aging texture

Medical Beauty After-Care

Mild microcapsule retinol for post-peel gentle anti-aging maintenance

Anti-Aging Sleeping Mask

Overnight renewal mask, fade dullness and shallow pigmentation

Strict QC Testing & Official Batch Compliance Documents


Each Retinol batch undergoes full HPLC testing for retinol content, retinal oxidation impurity, peroxide value, moisture, ignition residue, heavy metals, residual solvents and complete microbial inspection, fully compliant with ISO22716, CosIng and FDA cosmetic raw material standards.

We provide exclusive batch COA, HPLC spectrum test report, SDS safety data sheet, HALAL/KOSHER/ISO/GMP certification copies, third-party skin irritation safety evaluation reports, full batch traceability records, supporting cosmetic factory audits, global cosmetic registration and customs clearance.

Full Batch Traceability System

Unique batch number, complete synthesis, purification and testing records, permanent traceability for cosmetic compliance audits

OEM & Custom Formulation Service for Retinol


Customizable Service Range

  • 99% pure Retinol crystal powder fineness customization
  • 10% / 20% Retinol oil solution: customize carrier oil (sunflower / squalane / jojoba oil)
  • Slow-release microcapsule Retinol, adjustable encapsulation rate & irritation degree
  • Pre-blended soothing compound: Retinol + Centella + Panthenol + Vitamin E anti-aging premix
  • Bulk light-proof nitrogen vacuum packaging: 50g /1kg /5kg /25kg, private label outer packaging
  • Night cream & retinol serum formulation technical guidance, stability & irritation testing support

Support long-term framework bulk orders, stable retinol activity and low peroxide indicators, supply full regulatory documents including batch COA, SDS, test reports and certification copies to help cross-border cosmetic brands complete regional filing and customs clearance.

Light-proof vacuum customized Retinol bulk raw material packaging

How to buy Retinol Powder ?

Please feel free to contact us for any of your needs. You can send an email to admin@focusherb.com or submit your request at the bottom of the page. We will be happy to assist you!

Top Frequently Asked Questions about Retinol Powder


1. What is the CAS number, purity and specification of your Retinol Powder?

Our cosmetic-grade Retinol Powder is all-trans retinol (Vitamin A alcohol), CAS: 68-26-8, molecular formula C₂₀H₃₀O.

Standard purity: ≥98% / ≥99% verified by HPLC, pale yellow crystalline powder.

We add proprietary antioxidant stabilizer system inside powder to slow oxidation; full batch COA, HPLC chromatogram, isomer impurity test data are supplied.

Clear differentiation from Retinyl Acetate, Retinyl Palmitate powder (more stable ester derivatives with weaker activity).

2. What full safety & impurity testing is completed per batch?

Every batch conducts comprehensive tests:

Heavy metals (Pb, As, Cd, Hg), residual solvents, total isomer impurities (cis-retinol, anhydroretinol), peroxide value, microbial indicators (TPC, yeast & mold, E.Coli, Pseudomonas aeruginosa, Salmonella), heavy metal catalytic oxidation risk screening.

Comply with EU SCCS, CosIng, FDA, ISO22716, GMP cosmetic raw material standards. Complete test documents support global cosmetic registration, third-party factory audits and customs clearance.

3. What is the recommended dosage, applicable formulations & pH tolerance range?

Global regulatory upper limit for finished skincare: 0.3% retinol in leave-on facial products (follow local regional rules).

Typical formulation dosage: 0.05%–0.3% for anti-aging serums, firming creams, acne treatment gels, eye anti-wrinkle creams.
Stable pH window: 5.0–7.0; avoid strong acid, strong alkali,

long-term UV light & high temperature during production/storage, which trigger isomerization and activity loss.

Compatible with tocopherol, centella asiatica extract, hyaluronic acid, panthenol to reduce irritation; incompatible with metal ions, strong oxidants. Pre-formulation stability testing is mandatory.

4. Extremely critical: Shelf life, storage & packaging requirements

Retinol is highly sensitive to light, oxygen, heat and metal ions:

Unopened sealed powder under 2–8°C cold dark storage: 24 months shelf life

Room temperature sealed storage: only 6–12 months, activity declines rapidly

Liquid retinol formulations: 3–8 months (depends on inert gas filling & antioxidant system)

Packaging must use light-proof aluminum foil bags / opaque metal drums with desiccant, filled with nitrogen/argon inert gas to isolate oxygen.

After opening, seal tightly immediately, finish use within 1 month under refrigeration to prevent oxidation, yellowing and efficacy attenuation.

5. What’s the core difference between Retinol Powder, Retinyl Acetate and Retinyl Palmitate Powder?

Retinol (Vitamin A Alcohol Powder): Highest biological activity, direct skin efficacy; extremely unstable, strict cold storage required, high irritation risk for sensitive skin, used in high-performance anti-aging professional skincare.

Retinyl Acetate: Ester derivative, medium stability, moderate activity, balanced cost & performance.

Retinyl Palmitate: Most stable, lowest irritation, weakest whitening/anti-aging activity, mass-market daily skincare raw material.

Three items have different CAS, activity intensity, storage requirements and cannot substitute each other directly in formulas.

6. Is Retinol Powder vegan, allergen-free & available with HALAL/KOSHER certificates?

Our standard retinol powder is synthetic, vegan, cruelty-free, non-GMO, gluten-free, no parabens or artificial fragrances.
HALAL, KOSHER compliance documents can be provided for export brands upon request.

Retinol may trigger dryness, peeling or redness on sensitive skin at high concentrations; patch testing is compulsory for sensitive skin finished formulas.

7. What is MOQ, packaging and delivery timeline?

Sample MOQ: 5g for formulation stability testing

Bulk export packaging: 1kg / 5kg light-proof aluminum foil bags, 25kg opaque metal drums with inert gas filling

In-stock standard powder orders: 3–7 working days delivery (cold chain transport available)

Custom stabilized retinol liquid / microencapsulated retinol

powder: 7–14 working days production lead time

Long-term framework bulk orders supported with consistent

batch purity & stable activity retention.

8. Can I get free test samples and full compliance documents?

Qualified bulk buyers can apply for 5g free samples for compatibility & stability trials.

We supply batch COA, SDS/MSDS, HPLC test reports, GMP/ISO22716 certificates, full batch traceability records, SCCS safety evaluation materials, supporting REACH, CPNPF and overseas cosmetic filing & import clearance.

9. Why does retinol powder turn yellow/brown and lose efficacy? How to avoid it?

Discoloration and activity loss are mainly caused by three factors:

UV/light exposure, oxygen contact, high temperature + metal ion contamination.

Solutions:

Adopt nitrogen-filled inert gas sealed packaging; store at 2–8°C dark cold warehouse

Add tocopherol/BHT antioxidant in finished formulas

Use opaque raw material storage tanks, avoid stainless steel metal containers during production

Control workshop temperature below 30°C, shorten open-air operation time

We provide stability acceleration test reports for reference.

10. Do you support factory audit, third-party independent testing & customized stabilized grades?

Our production line operates under GMP & ISO22716 clean cosmetic workshop standards, with full temperature-controlled cold storage warehouse for retinol stock.

We welcome on-site factory audits, third-party independent lab testing; customized stabilized retinol powder with enhanced antioxidant system and microencapsulated retinol are available to improve formula stability.

Have any questions?
Let's get in touch!

Contact us if your are thinking of purchasing highquality ingredients, develop new products, or justsolving a manufacturing challenge in your rawmaterials.

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