Cosmetic Ingredients
Sodium Hyaluronate Powder
Sodium Hyaluronate Powder is the sodium salt form of Hyaluronic Acid, fermented from Streptococcus zooepidemicus, featuring ultra-high water-locking capacity and excellent biocompatibility. We supply full molecular weight series and three industrial grades, widely used in cosmetic skin care, oral beauty supplements, joint health products and medical injection filler materials.
All batches comply with USP, EP, FCC, CosIng and FDA standards. Strictly tested for heavy metals, protein residues, endotoxin and microbiological indicators. Support customized molecular weight cutting and provide complete COA, SDS, test reports for global brand filing and customs clearance.
Full MW HA
Water Soluble
Food Safe
Medical Grade Available
PRODUCT INTRODUCTION
| Product Name | Sodium Hyaluronate Powder |
| CAS No. | 9004-61-9 |
| Appearance | White fine powder, odorless, highly hygroscopic |
| Purity | ≥98% / ≥99% HPLC |
| Molecular Weight | 500Da–2000kDa customizable (ULW/LW/MW/HW) |
| Solubility | 100% soluble in purified water, insoluble in oil & ethanol |
| Moisture | ≤10.0% |
| Protein Impurity | Cosmetic ≤0.1%; Food/Medical ≤0.05% |
| Heavy Metal | Pb<1ppm, As<1ppm, Cd<0.1ppm, Hg<0.1ppm |
| Microbiology | TPC<100CFU/g, Mold&Yeast<10CFU/g, Pathogen Negative |
| Endotoxin | Medical grade ≤0.1EU/mg |
| Stable pH Range | 5.0–8.0 |
| Storage | Sealed, moisture-proof, cool dry place, avoid high temperature & strong light |
| Shelf Life | 24 months sealed storage |
| Packaging | 10g sample / 100g / 1kg / 5kg / 25kg aluminum foil vacuum bag |
Molecular Weight Application Matching Table
| HA Molecular Weight | Range | Core Application |
| Ultra Low MW | <10KDa | Deep transdermal absorption, anti-aging, post-sun repair, sensitive skin barrier recovery |
| Low MW | 10–100KDa | Epidermis moisturizing, redness relief, daily skincare essence & lotion |
| Medium MW | 100–1000KDa | Universal moisturizing for cream, toner, mask, stable formula base |
| High MW | 1000–2000KDa | Surface film-forming, long-lasting water locking, medical filler & joint lubrication |
Core Benefits & Action Mechanism
Sodium Hyaluronate is the most widely used hyaluronic acid form with better water solubility and stability than pure HA. Different molecular weights achieve layered skin care: high molecular weight forms a breathable protective film to lock surface moisture; medium molecular weight maintains epidermal hydration; low and ultra-low molecular weight penetrate deep into the dermis, stimulate collagen proliferation, repair damaged skin barrier and fade fine lines.
Orally intake HA replenishes whole-body hyaluronic acid reserves, improves skin dryness, relieves joint friction and soreness, lubricates articular cavities. Medical-grade low-endotoxin sodium hyaluronate is safe for subcutaneous filling, wrinkle removal and ophthalmic lubrication treatment.
- 500x super water-locking capacity, adaptive intelligent moisturizing for dry environment
- DFull-layer skin repair: surface locking, middle hydration, deep anti-aging
- Oral joint lubrication & whole-body skin hydration
- Non-irritating, hypoallergenic, suitable for sensitive skin and pregnant skincare
- High formula compatibility with peptides, vitamins, plant extracts
- Medical-grade low endotoxin, compliant for dermal filler & medical biomaterials
Formula Dosage Guide: Cosmetic addition 0.05%–0.3%; oral supplement 50–200mg per serving; avoid heating over 80℃ and long-term strong acid storage to prevent molecular degradation.

Microbial Fermentation & Purification Process
Full Production Process
- Sterile fermentation tank culture of Streptococcus zooepidemicus strain
- Constant temperature & pH aerobic fermentation to synthesize crude HA liquid
- High-speed centrifugation & ultrafiltration to remove bacteria and protein impurities
- Multi-stage alcohol precipitation & decolorization purification
- Low-temperature vacuum freeze drying to retain molecular activity
- Precision molecular weight cutting & grading screening
- Sterile testing & moisture-proof vacuum packaging
GMP 100,000-class clean workshop, full sterile closed production. Strictly control protein residue, endotoxin and heavy metals to meet cosmetic, food and medical triple standards. Custom molecular weight available.

Factory Supply Capacity & Global Certifications
Professional HA fermentation factory with annual output of 30 tons of sodium hyaluronate powder, 1-ton regular spot inventory covering all molecular weights and grades. Constant temperature moisture-proof warehouse ensures no agglomeration and stable activity, supporting long-term bulk orders for global cosmetic, health food and medical manufacturers.
Stable Supply Advantages
- Annual capacity: 30 tons full-spec Sodium Hyaluronate Powder
- Full molecular weight & three grades in stock
- Custom MW cutting & low endotoxin customization
- 7–10 days fast bulk delivery, long-term order discount

Batch COA & SDS Full Official Documents
- ISO22716, ISO22000, GMP factory certification
- USP/EP/FCC pharmacopoeia compliance for medical grade
- FDA GRAS, EU CosIng listed, HALAL & KOSHER approved
- Provide REACH, CPNP, batch traceability documents
6 Core Competitive Advantages
Full MW Customizable
Ultra-low to high molecular weight adjustable, match all skincare and oral formula needs.
Three-Grade Complete
Cosmetic / Food / Medical injectable grades meet beauty, health and medical scenarios.
Fermented Vegan Source
Microbial fermentation, no animal source, clean label & safe.
Ultra-Low Impurity
Strict control endotoxin, protein and heavy metals, meet pharmacopoeia standard.
Global Compliance
Full certificates support US/EU overseas filing and customs clearance.
Strong Compatibility
Stable matching with peptides, vitamins and plant extracts for complex formulas.
Request Free Sample & Bulk Quotation
Looking for a reliable supplier of multi-molecular weight Sodium Hyaluronate Powder raw material for moisturizing serums, facial masks, skincare creams and food & oral care formulations?
Contact our team today to receive free samples, full COA specifications, global export certification documents and customized bulk pricing for your hyaluronic acid cosmetic & food raw material project.
Multi-Industry Application Scenarios
Hydrating Serum & Toner
Deep moisturizing anti-aging essence formula
Barrier Repair Cream
Sensitive skin soothing & post-sun repair
Oral Beauty Capsules
Skin hydration oral supplement tablets
HA Beauty Drink
Liquid oral beauty & anti-aging beverage
Medical Dermal Filler
Subtle wrinkle removal & volume filling
Joint Health Care
Joint lubrication & osteoarthritis relief
Strict QC Testing & Batch Compliance Documents
Every batch of Sodium Hyaluronate completes full-index testing including HPLC content, viscosity molecular weight, moisture, residue, heavy metals, solvent residue and microbiological detection. Medical grade adds endotoxin testing to meet USP injection standards.
We provide exclusive batch COA, HPLC chromatogram, SDS safety sheet, GMP/ISO/HALAL/KOSHER certificates, safety assessment reports and full batch traceability records.
Full Batch Traceability
All production & testing data permanently archived for compliance audit
OEM & Custom Service
Customizable Items
- Custom molecular weight precision cutting according to formula requirements
- Three-grade customization: cosmetic / food / low endotoxin medical grade
- Compound premix: HA + collagen + VC + glutathione blended powder
- Custom vacuum moisture-proof packaging & private label service
- Formula technical guidance: dissolution method, viscosity adjustment, stability solution
Support long-term framework orders with stable batch consistency. Provide full compliance documents to support overseas brand filing, factory audit and customs clearance.

How to buy Sodium Hyaluronate Powder ?
Please feel free to contact us for any of your needs. You can send an email to admin@focusherb.com or submit your request at the bottom of the page. We will be happy to assist you!
Have any questions?
Let's get in touch!
Contact us if your are thinking of purchasing highquality ingredients, develop new products, or justsolving a manufacturing challenge in your rawmaterials.



















