Alpha-Ketoglutarate

What is Alpha-Ketoglutarate?

Alpha-Ketoglutarate (AKG) is an important organic compound and a key intermediate product in the TCA cycle (also known as the Krebs cycle). It plays an important role in cellular metabolism, energy production, and various physiological processes.

1. Metabolic Functions

Energy Production: Alpha-Ketoglutarate is part of the tricarboxylic acid (TCA) cycle, which plays a role in energy production within cells. During this process, it is reduced to succinate, releasing energy.

Nitrogen Metabolism: Alpha-Ketoglutarate plays a key role in the transport and metabolism of nitrogen. It is the product of glutamate dehydrogenase and can convert ammonia into glutamine, which is the main form of ammonia transport.

2. Antioxidant Functions

Clearing Free Radicals: Alpha-Ketoglutarate has a certain antioxidant capacity, which can help clear free radicals in the body and reduce oxidative stress damage to cells.

Protecting Cells: Through its antioxidant functions, Alpha-Ketoglutarate helps protect cells from oxidative damage and maintain normal cell function.

3. Muscle and Bone Health

Promoting Muscle Synthesis: Alpha-Ketoglutarate can promote the synthesis of muscle proteins, helping with muscle growth and repair. This is especially important for athletes and the elderly.

Reducing Muscle Fatigue: Alpha-Ketoglutarate can reduce muscle fatigue caused by exercise, improving athletic performance.

4. Immune Support

Enhancing Immune Function: Alpha-Ketoglutarate can enhance the function of the immune system,