Food and Nutrition Ingredients
Reduced Nicotinamide Mononucleotide (NMNH)
Reduced Nicotinamide Mononucleotide (NMNH, CAS:108347-85-9) is the reduced form of β-NMN, a next-generation water-soluble NAD+ precursor synthesized via full enzymatic bioreduction. Compared with regular NMN, NMNH skips intracellular enzymatic reduction steps, raises cellular NAD+ levels 5-10 times faster, maintains high NAD+ concentration for up to 24 hours, greatly improving bioavailability for aging cells with low enzyme activity.
We supply HPLC 98%/99% standard NMNH disodium salt powder and liposome encapsulated stable NMNH. Strictly control oxidation impurities, heavy metals, residual solvents and microbes, compliant with FDA GRAS, CosIng, ISO22716, GMP, HALAL & KOSHER. Free test samples and complete COA & SDS documents are provided for formula development and overseas filing.
NMNH
Reduced NMN
Water Soluble NAD Precursor
FDA GRAS Certified
Anti-photoaging Cosmetic Ingredient
Reduced NMN
Water Soluble NAD Precursor
FDA GRAS Certified
Anti-photoaging Cosmetic Ingredient
PRODUCT INTRODUCTION
| Product Name | Reduced Nicotinamide Mononucleotide (NMNH), Disodium Salt |
| CAS No. | 108347-85-9 |
| Molecular Formula | C₁₁H₁₈N₂NaO₈P |
| Molecular Weight | 360.23 g/mol |
| Appearance | Light yellow to off-white fine powder, odorless |
| NMNH Content (HPLC) | ≥98.0% / ≥99.0% |
| Oxidized NMN Impurity | ≤1.0% |
| Solubility | Freely soluble in water; slightly soluble in methanol; insoluble in oils |
| Loss on Drying | ≤8.0% |
| Residue on Ignition | ≤1.0% |
| Heavy Metals | Pb ≤0.1ppm, As ≤0.1ppm, Cd ≤0.05ppm, Hg ≤0.01ppm |
| Microbiological Index | TPC ≤100cfu/g, Mold & Yeast ≤10cfu/g, Salmonella/E.coli Negative |
| Allergen Status | Non-GMO, Vegan, Gluten-Free, no artificial additives |
| Stable pH Range | pH 4.0~8.0 stable; degrade rapidly under strong alkaline, high temperature & light exposure |
| Storage Condition | Nitrogen-filled light-proof vacuum sealed package, store at -20~20℃; strictly avoid light, oxygen & high humidity |
| Unopened Shelf Life | 24 months under standard cold dark sealed storage |
| MOQ | 10g sample; bulk:100g/1kg/5kg/25kg vacuum package |
Core Benefits & Functional Mechanism of NMNH
NMNH is the direct precursor of NADH/NAD+, eliminating the cellular reduction step required for regular NMN conversion. It enters cells via ENT transporters rapidly, drastically boosting intracellular NAD+ within 15 minutes. High NAD+ optimizes mitochondrial ATP energy generation, accelerates DNA damage repair, inhibits chronic inflammation, supports neuronal metabolism and sleep cycle regulation. For topical skincare, NMNH elevates epidermal NAD+, repairs UV photodamage, accelerates barrier recovery, reduces fine dry lines, brightens dull skin and alleviates sensitive inflammation after medical beauty treatments.
Conventional NMNH powder is water-soluble yet sensitive to oxidation; liposome modification solves light/oxygen instability and achieves oil-water amphipathic solubility. Classic compound formulas: oral NMNH + PQQ + Resveratrol full anti-aging stack; skincare NMNH + Nicotinamide + Ceramide photo-repair sensitive skin formula.
- Higher NAD+ efficiency: 5~10 times faster NAD elevation vs NMN, long-lasting efficacy for 24 hours
- Bypasses NAMPT limitation: works well for older populations with low NAMPT enzyme activity
- Dual oral & topical value: cellular anti-aging internally; photo damage & barrier repair externally
- Liposome customization available: stable for cream, oil serum, soft capsules
- Endogenous safe nutrient: human native metabolite, long-term oral safe without dependency
Formulation Tips: Oral daily dosage 200–1000mg; skincare recommended addition 0.05%~0.2%. Final products must use opaque oxygen-block packaging; avoid heating over 60℃ and alkaline formula systems. Long-term storage requires low-temperature sealed preservation.
NMNH Full Enzymatic Synthesis & Purification Process
Full Production Process Steps
- High-purity β-NMN raw material incoming inspection, heavy metal & solvent pre-test
- Closed nitrogen-protected enzymatic reduction reaction under low temperature, strict pH control
- Membrane ultrafiltration removes enzyme protein macromolecular impurities
- Multi-step reversed-phase chromatography separation to remove oxidized NMN impurities
- Low-temperature vacuum freeze drying to avoid thermal oxidation degradation
- Optional liposome embedding process for light/oxygen stability improvement
- HPLC full index inspection, nitrogen-filled opaque vacuum packaging
GMP clean closed workshop, full-process nitrogen protection, low temperature and light avoidance to prevent NMNH oxidative degradation. Strict impurity control ensures consistent purity across batches, meeting global food and cosmetic raw material safety standards.
Factory Supply Capacity & Global Export Certifications
Professional nucleotide GMP production factory, annual NMNH total output reaches 3 tons, regular spot inventory 180kg. Independent constant-temperature dark nitrogen sealed warehouse prevents oxidation deterioration, stably supplies bulk raw materials to global anti-aging oral factories and photo-repair skincare OEM manufacturers.
Stable Bulk Supply Advantages
- Annual capacity: 3 tons full-spec NMNH powder (98%/99%) + liposome customized batches
- In-stock inventory: 180kg conventional specifications support fast delivery
- Custom liposome stabilization, NAD+ multi-ingredient compound premix powder
- 5~8 working days bulk delivery, long-term framework order volume discount pricing
Batch COA & SDS Full Official Documents
- ISO22716 & GMP unified production standards for food and cosmetic raw materials
- US FDA GRAS certification, EU food safety + CosIng cosmetic filing eligible
- Dual HALAL & KOSHER certification supporting global religious market exports
- Third-party full testing for oxidation impurities, heavy metals, solvents + complete batch traceability
- Provide REACH, CPNP documents to support overseas brand registration and customs clearance
6 Core Competitive Advantages of Our NMNH
Ultra-Fast NAD+ Activation
5-10 times higher NAD boosting efficiency than regular NMN, faster onset and 24-hour long effect
Bypass NAMPT Enzyme Barrier
No enzyme conversion required, suitable for aging groups with insufficient NAMPT activity.
Natural Water Solubility
Easy to formulate into oral drinks, toners, essences; liposome version matches oil formulas.
Oral & Topical Dual Use
Internal anti-aging energy support; external UV repair, barrier recovery and anti-wrinkle.
Global Dual Compliance
Food/cosmetic dual certification, complete documents for US & EU cross-border filing.
Stability Customization
98%/99% raw powder available; liposome anti-oxidation customization for unstable formulas.
Request Free Sample & Bulk Quotation
Looking for a reliable supplier of high purity Reduced Nicotinamide Mononucleotide (NMNH) raw material for cellular energy supplements, anti-aging longevity capsules and premium nutritional formulations?
Contact our team today to receive free samples, full COA specifications, global export certification documents and customized bulk pricing for your high-efficiency NAD-boosting health raw material project.
Main Industrial Application Fields for NMNH
Anti-Aging NAD+ Capsules
High-end longevity anti-aging oral hard/soft capsules
Energy & Metabolism Tablets
Fatigue relief, mitochondrial energy nutritional tablets
Sleep & Nerve Support Oral
Improve deep sleep, brain focus & nervous relaxation
UV Repair Facial Serum
Photodamage DNA repair, anti-dull brightening essence
Medical Beauty Repair Cream
Post-laser sensitive barrier repair anti-inflammatory cream
Oral Beauty Drinks
Anti-aging oral liquid, effervescent solid beverage
Strict QC Testing & Official Batch Compliance Documents
Each batch of NMNH completes full HPLC content detection, oxidized impurity assay, moisture, ignition residue, heavy metals, solvent residues and microbial comprehensive testing, fully compliant with ISO22716, FDA GRAS, CosIng global raw material standards. Special oxidation stability test is added for batch screening.
We provide exclusive batch COA, HPLC chromatogram report, SDS safety data sheet, HALAL/KOSHER/ISO/GMP certification copies, food/cosmetic safety evaluation reports and full batch traceability files, supporting factory audits, global health products and cosmetics registration and customs clearance.
Whole Batch Traceability Management
Unique batch number records synthesis, purification, testing links, permanently traceable for compliance audit
OEM & Custom Formulation Service for NMNH
Customizable Service List
- NMNH purity customization:98%/99%, powder particle fineness adjustment
- Liposome encapsulated NMNH customization for anti-oxidation and oil-water dual solubility
- NAD compound premix: NMNH + NMN + PQQ + Resveratrol customized blending ratio
- Bulk nitrogen oxygen-barrier vacuum packaging:50g/1kg/5kg/25kg, private label outer package available
- Formula technical guidance for oral tablets/capsules, serums, creams, plus oxidation stability testing
We support long-term framework bulk orders with stable low oxidation impurity indicators. Provide complete compliance documents including batch COA, SDS, safety assessment report, helping cross-border health food and cosmetic brands complete regional filing and customs clearance smoothly.
How to buy Reduced Nicotinamide Mononucleotide ?
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