Cosmetic Ingredients
GHK-Cu(Copper Peptide)
GHK-Cu (Copper Peptide / Tripeptide-1 Copper, CAS:49557-75-7) is a glycyl histidyl lysine copper chelate complex, a classic signal peptide cosmetic raw material with blue appearance. It stimulates skin repair, boosts collagen synthesis, reduces inflammation, fades fine lines, and soothes sensitive & damaged skin.
Our GHK-Cu is available in 99% pure powder and custom concentration solutions (0.1%~5%), tested by HPLC, compliant with CosIng, FDA, ISO22716, GMP, HALAL & KOSHER standards. Ideal for anti-aging serums, repair masks, post-procedure skincare, sensitive skin formulations, clean beauty & vegan formulas. Stable batches, bulk factory price, full COA & SDS available, free samples offered.
Copper Peptide
Tripeptide-1 Copper
HPLC Verified
Clean Beauty Raw Material
HALAL & KOSHER Certified
Tripeptide-1 Copper
HPLC Verified
Clean Beauty Raw Material
HALAL & KOSHER Certified
PRODUCT INTRODUCTION
| Product Name | GHK-Cu / Copper Peptide / Tripeptide-1 Copper / Glycyl Histidyl Lysine Copper |
| CAS No. | 49557-75-7 |
| Molecular Formula | C₁₄H₂₄CuN₆O₄ |
| Appearance (Pure Powder) | Blue to blue-violet fine crystalline powder, slight characteristic odor |
| Appearance (Solution) | Clear blue aqueous/glycerin solution |
| Purity (HPLC) | 99% (pure powder), custom concentrations: 0.1%, 0.5%, 1%, 5% solution |
| Solubility | Freely soluble in water, water-glycerin systems; slightly soluble in ethanol |
| pH (1% aqueous solution) | 4.5 ~ 6.5 |
| Moisture | ≤3.0% |
| Heavy Metals | Pb ≤0.1ppm, As ≤0.1ppm, Cd ≤0.05ppm, Hg ≤0.01ppm, compliant with cosmetic raw material standards |
| Microbiology | TPC ≤100cfu/g, Yeast & Mold ≤10cfu/g, E.Coli / Salmonella / Pseudomonas aeruginosa: Negative |
| Impurity Content | Single impurity ≤0.5%, total impurities ≤1.0% (HPLC) |
| Allergen Status | Vegan, Gluten-Free, Non-GMO, No added parabens / fragrances |
| Storage Condition | Sealed, cool dry dark warehouse (2-8℃ recommended), avoid direct sunlight, high temperature & alkaline environments |
| Shelf Life | 24 months unopened (2-8℃), 12 months at room temperature; solution: 6-12 months (preserved system) |
| MOQ | 10g sample order, 1kg / 5kg / 25kg bulk export packaging |
Core Benefits & Functional Mechanism
GHK-Cu is a copper chelate of the tripeptide Glycyl-L-Histidyl-L-Lysine. The peptide acts as a cell signal to regulate skin regeneration, while copper is an essential trace mineral for enzyme function, collagen synthesis, and skin repair processes. It stimulates fibroblasts to produce collagen, elastin, and glycosaminoglycans, accelerating wound repair and barrier recovery, while inhibiting inflammatory cytokines and scavenging free radicals.
Unlike many high-potency anti-aging ingredients (e.g., retinol), GHK-Cu has very low irritation, making it suitable for sensitive skin, post-laser/chemical peel repair formulas, long-term daily anti-aging formulations, and clean beauty products. It works synergistically with hyaluronic acid, centella asiatica extract, and ectoin for barrier repair and anti-redness formulas.
- Skin barrier repair: boost collagen & elastin synthesis, restore damaged barrier, reduce transepidermal water loss
- Anti-aging & anti-wrinkle: improve skin elasticity, reduce fine lines, sagging, and photoaging damage
- Anti-inflammatory & soothing: relieve redness, sensitive skin, rosacea discomfort, post-procedure inflammation, and acne marks
- Antioxidant protection: neutralize free radicals, reduce oxidative stress, slow premature aging
- Wound healing support: accelerate microdamage repair, ideal for medical beauty & regenerative skincare
- Mild & compatible: non-irritating, adaptable to most aqueous cosmetic formulations, vegan & clean label friendly
GHK-Cu Peptide Synthesis & Chelation Process
Full Manufacturing Steps
- Amino acid raw material selection: L-Glycine, L-Histidine, L-Lysine of high purity cosmetic grade
- Solid-phase peptide synthesis: assemble GHK tripeptide via controlled peptide coupling reactions
- Cleavage & purification: remove protecting groups, purify crude tripeptide via chromatography
- Copper chelation: controlled pH chelation with copper salts to form stable GHK-Cu complex
- Purification & desalting: remove residual salts, impurities and unreacted raw materials
- Drying / formulation: vacuum freeze-drying to obtain pure blue powder OR dissolve into specified solvent for liquid formulations
- Quality testing & packaging: HPLC purity test, microbial & heavy metal inspection, sealed moisture-proof packaging
GMP cosmetic peptide clean workshop, strictly controlled chelation pH & temperature to ensure stable copper chelate structure, consistent blue color, high purity, low impurities, meeting global cosmetic raw material standards and ISO22716 requirements.
Factory Supply Capacity & Global Certifications
Professional cosmetic peptide GMP production base, annual GHK-Cu output reaches 500kg pure powder, multiple solution formulations in regular stock, 50kg+ spot inventory for fast sample & bulk orders, temperature-controlled dark storage to prevent color shift and peptide degradation.
Stable Bulk Supply Advantages
- Annual production capacity: 500kg 99% pure GHK-Cu powder, custom liquid batches available
- Regular spot inventory: 50kg standard pure powder, pre-made 0.1%/1% stock solutions
- Custom concentration, solvent (water/glycerin/butylene glycol) and preservative systems
- 3~7 working days fast delivery for standard orders, 7-14 days for custom formulations
Batch COA & SDS Full Documents
- ISO22716 / GMP Cosmetic Good Manufacturing Practice
- CosIng EU cosmetic raw material compliance, FDA cosmetic ingredient compliance
- HALAL & KOSHER global religious export certification
- Third-party cosmetic safety testing & permanent batch traceability
- REACH, CPNPF & regional cosmetic filing support documents
6 Core Competitive Advantages of Our GHK-Cu Copper Peptide
High Purity Stable Chelate
99% HPLC verified GHK-Cu, complete copper chelation, consistent blue color, minimal free copper ions, no color shift, reliable long-term formulation stability.
Dual Repair & Anti-Aging
Combines barrier repair, anti-inflammatory soothing, anti-wrinkle & antioxidant effects; perfect for sensitive skin, post-procedure repair and daily anti-aging skincare lines.
Clean Beauty & Vegan Friendly
Vegan, gluten-free, non-GMO, no parabens/animal-derived ingredients, fully aligned with clean beauty, natural & sustainable cosmetic trends
Mild Low-Irritation Formula
Far gentler than retinol & acid actives, suitable for sensitive, rosacea-prone and fragile skin, reduces adverse reactions in repair & medical beauty formulations.
Global Cosmetic Compliance
Compliant with EU CosIng, US FDA, ISO22716, HALAL & KOSHER, supports global cosmetic registration, filing and customs clearance documents.
Flexible Custom Formulation
Custom powder grades, multiple solvent solutions, preservative systems, private labeling, formulation guidance & dosage recommendations for OEM skincare brands.
Request Free Sample & Bulk Quotation
Looking for a reliable supplier of cosmetic grade GHK-Cu copper peptide raw material for anti-aging skincare serums, facial creams, essence and beauty ampoules?
Contact our team today to receive free samples, full COA specifications, global export certification documents and customized bulk pricing for your anti-aging cosmetic raw material project.
Main Industrial Application Fields
Anti-Aging Serums & Essences
Anti-wrinkle serums, ampoules, essence water, improve elasticity & reduce fine lines
Repair Masks & Sheet Masks
Barrier repair masks, soothing masks, relieve redness & sensitive skin discomfort
Eye Creams & Anti-Aging Creams
Eye creams, firming face creams, reduce under-eye lines and sagging skin
Medical Beauty Repair Products
Post-laser / peel repair gels, sprays, soothe inflammation and speed skin recovery
Sensitive Skin & Rosacea Care
Redness relief creams, calming toners, chronic sensitive skin daily care formulas
Clean Beauty & Vegan Skincare
Natural clean formulas, vegan skincare, organic cosmetic lines
Strict QC Testing & Official Batch Documents
Every batch of GHK-Cu is tested via HPLC for peptide purity, chelation ratio, pH, color, moisture, heavy metals, full microbiology and cosmetic safety testing, complying with ISO22716, CosIng, FDA cosmetic raw material specifications.
We provide official batch COA, HPLC test reports, SDS safety data sheets, HALAL/KOSHER/ISO/GMP certificates, third-party cosmetic safety assessment reports, full batch traceability records, supporting cosmetic factory audits, global cosmetic registration and customs clearance.
Full Batch Traceability System
Unique batch number, full peptide synthesis & testing records, permanent batch traceability for cosmetic compliance audits
OEM & Custom Formulation Service
Customizable Service Range
- Pure powder: 99% standard powder, ultra-fine mesh customization
- Liquid formulations: 0.1% / 0.5% / 1% / 5% concentration, water/glycerin/butylene glycol solvent systems
- Preservative system customization (preservative-free / gentle preservative options)
- Blend pre-mixes: GHK-Cu + hyaluronic acid / centella asiatica / ectoin repair blends
- Bulk packaging: 10g / 100g / 1kg / 5kg / 25kg, neutral drums/bags, private label custom packaging
- Cosmetic formulation technical support, dosage guide, stability testing guidance
Support long-term framework bulk orders, consistent batch color & purity, provide full cosmetic regulatory documents (COA, SDS, test reports, certification copies) for global cosmetic brands to complete regional filing and compliance verification.
How to buy GHK-Cu?
Please feel free to contact us for any of your needs. You can send an email to admin@focusherb.com or submit your request at the bottom of the page. We will be happy to assist you!
GHK-Cu Copper Peptide Wholesale & B2B Procurement FAQ
What is the MOQ for GHK-Cu bulk orders?
Our standard MOQ is 10g for sample evaluation, 1kg for regular bulk orders, and larger quantities such as 5kg / 25kg are available for industrial production. We also support long-term supply agreements for cosmetic brands and formulation manufacturers.
Can we provide free samples before bulk purchase?
Yes. We provide free GHK-Cu samples for qualified customers to test purity, color, solubility, formulation compatibility and stability before placing bulk orders. Sample size and shipping method can be discussed with our sales team.
What documents can my provide for cosmetic compliance and quality verification?
For every batch, we can provide complete documentation including:
- COA (Certificate of Analysis)
- HPLC purity test report
- SDS (Safety Data Sheet)
- Specification sheet
- Microbiology & heavy metal test reports
- GMP / ISO22716 certificates
- HALAL & KOSHER certificates
- Batch traceability records
These documents support cosmetic factory audits, regulatory filing and global import requirements.
Due to the large number of quality inspection records and compliance documents available for different markets and customer requirements, we do not display all testing materials publicly. Please contact us, and we will provide the specific documents and reports required for your project evaluation.
Can we support OEM and custom formulation requirements?
Yes. We provide flexible customization services including:
- 99% pure GHK-Cu powder
- 0.1% / 0.5% / 1% / 5% liquid solutions
- Water, glycerin or butylene glycol solvent systems
- Preservative system customization
- GHK-Cu blended ingredients (such as HA, Centella asiatica, Ectoin)
- Private label and customized packaging
Our technical team can assist with formulation recommendations and stability evaluation.
Why choose Focusherb GHK-Cu supplier instead of other peptide manufacturers?
Our advantages include:
- 99% HPLC verified purity
- Stable copper peptide chelation structure
- GMP cosmetic production environment
- Reliable bulk supply capacity
- Complete compliance documentation
- Flexible OEM customization
- Long-term batch consistency support
We help cosmetic brands, OEM manufacturers and distributors build stable GHK-Cu supply chains worldwide.
What is the typical lead time for bulk orders?
For standard products in stock:
- Samples: usually shipped within 3–5 working days
- Bulk orders: approximately 3–7 working days
For customized concentrations, packaging or special formulations, production normally requires 7–14 working days depending on order requirements.
How do ensure batch-to-batch quality consistency?
Each production batch undergoes strict quality control, including:
- HPLC purity verification
- Copper chelation ratio testing
- pH testing
- Moisture analysis
- Microbial testing
- Heavy metal analysis
- Appearance and color inspection
All batches are recorded with unique batch numbers for full traceability.
GHK-Cu suitable for sensitive skin and medical beauty repair products?
Yes. GHK-Cu is widely used in sensitive skin care, barrier repair products and post-procedure skincare formulations due to its mild profile and skin repair benefits. It is commonly applied in:
- Post-laser repair products
- Soothing serums
- Barrier creams
- Anti-aging formulas
- Medical beauty aftercare products
What packaging options are available for bulk export?
We provide export-standard packaging options including:
- 10g laboratory sample packaging
- 100g small batch packaging
- 1kg / 5kg aluminum foil bags
- 25kg export drums
Customized labeling and private packaging are available for qualified B2B customers.
Can we support international shipping and customs clearance?
Yes. We support worldwide export shipments and provide necessary commercial documents, including:
- Commercial invoice
- Packing list
- COA
- SDS
- Certificate documents
- Shipping support documents
Our team can assist customers with import compliance requirements.
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