Genistein

What Is Genistein?

Genistein is a natural isoflavone compound that is mainly found in soybeans and other legumes. For example, soybeans, clover, kudzu root, locust, genistein (bruce), and broad bean root.

It belongs to the phytoestrogen class of compounds, which are derived from plants and have a chemical structure similar to estrogen (the main female sex hormone). Therefore, genistein can bind to estrogen receptors in the body, although its effect is much weaker than the body’s own estrogen.

In addition, genistein has the effects of inducing programmed cell death, improving anti-cancer efficacy, and inhibiting angiogenesis. It is a potential cancer chemopreventive agent, and its anti-cancer effects and mechanisms have broad application prospects.

Characteristics of Genistein

The Effect of Genistein 

As a phytoestrogen (estrogen-like compounds from plants) and antioxidant, genistein has a variety of potential effects on the human body. The main effects of genistein are as follows:

Balancing hormones
Estrogenic effects: Because genistein’s chemical structure is similar to estrogen, it can bind to estrogen receptors in the body. This may help balance hormone levels, especially in postmenopausal women or women with hormone imbalances. It can relieve some common menopausal symptoms, such as hot flashes, night sweats, and mood swings, by exerting a weak estrogenic effect.

Cancer prevention
Antitumor properties: Genistein has been shown to have the potential to inhibit the growth of certain types of cancer cells, especially breast and prostate cancer, both of which are affected by estrogen. Genistein can inhibit cancer cell proliferation, induce cancer cell death (apoptosis), and prevent tumor formation.

Antioxidant and anti-inflammatory effects
Reducing oxidative stress: Genistein is a powerful antioxidant that can neutralize free radicals that can damage cells and contribute to aging and the development of disease. By reducing oxidative stress, it may help prevent diseases such as cardiovascular disease, Alzheimer’s disease, and certain types of cancer.

Bone health
Preventing Osteoporosis: Genistein may have a positive effect on bone density by mimicking the effects of estrogen on bone metabolism. It may help prevent bone loss, which is especially important for postmenopausal women who are at higher risk for osteoporosis. Genistein may help improve bone density and reduce the risk of fractures in postmenopausal women.

Cardiovascular health
Cholesterol and Blood Pressure: Some research suggests that genistein may help improve heart health by lowering blood pressure, reducing low-density lipoprotein (LDL) cholesterol levels, and raising high-density lipoprotein (HDL) cholesterol levels. These effects can help improve cardiovascular health and reduce the risk of heart disease.

Cognitive health
Neuroprotective Effects: Genistein’s antioxidant properties extend to the brain and may help protect neurons from oxidative damage. Some research suggests that genistein may help reduce the risk of neurodegenerative diseases such as Alzheimer’s disease, but more research is needed to fully understand its effects on brain health.

Metabolic health
Weight Management: Some research suggests that genistein may help regulate metabolism and aid in weight management. By affecting lipid metabolism and insulin sensitivity, it may help reduce the risk of metabolic disorders such as type 2 diabetes.

The Application of Genistein 

Genistein has a wide range of potential applications due to its biological effects, especially its properties as a phytoestrogen, antioxidant and anti-inflammatory agent. The main applications of genistein are as follows:

• Cosmetics and skin care products
• Pharmaceutical raw materials
• Health products

The Advantages of Genistein  

Genistein has many advantages due to its unique properties as a phytoestrogen, antioxidant and anti-inflammatory agent.

FocusHerb has been focusing on the production of plant extracts for more than ten years. We control the quality and stability of raw materials from the source. From the entry of raw materials to the final product, we strictly follow GMP requirements to ensure the product quality of Sophora japonica glycosides.

The company has advanced imported testing equipment to ensure traceability testing from raw materials to production. The professional technical team strictly controls product quality. Low pesticide residues, low solvent residues and high purity are the basis of our products.

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